This collection of discussions is marked by a collective stance that grains and gluten are toxic to human health, with posts referencing the role of zonulin to explain how grains may increase intestinal permeability and cause autoimmune reactions. Words like 'toxic,' 'harmful,' and 'junk' reflect a tone of alarm and conviction, emphasizing the perceived significance and impact of the research on dietary habits.
AgreementStrong agreement
Most discussions strongly support the article’s premise that grains and gluten trigger increased intestinal permeability via zonulin, emphasizing the toxicity of grains.
InterestHigh interest
The community shows high curiosity and concern, with many posts discussing potential health risks and autoimmune implications.
EngagementHigh engagement
Users delve into detailed arguments, citing scientific concepts, and referencing related research, indicating deep engagement.
ImpactHigh impact
The conversations suggest a significant influence on beliefs about diet and health, potentially prompting behavioral changes towards grain consumption.
Abstract in brief
The intestine has a crucial role beyond digestion, specifically in regulating immune responses by controlling the movement of environmental antigens through tight junctions (TJs) in the mucosal barrier.
TJs are dynamic structures that must be quickly and precisely regulated to maintain nutrient absorption and immune balance, but much about how they are controlled under normal and disease conditions remains unknown.
The discovery of zonulin, a natural modulator of TJs, has provided insight into how TJ regulation can influence autoimmune diseases, especially in genetically predisposed individuals, by affecting intestinal permeability.
“There are at least 50 toxic epitopes in gluten peptides exerting cytotoxic, immunomodulatory, and gut permeating activities”
Zonulin, regulation of tight junctions, and autoimmune diseases https://t.co/Ddgh1fEa5c
Oct 8, 2021 · 6 likes · 2 shares · 5,568 followersView post →
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thalesnemo
@thalesnemo · X
@ElieJarrougeMD Grains have ZERO place in the human diet irrespective of any overt symptoms!
Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/ilzYZgbVx7
Feb 18, 2024 · 3 likes · 1 share · 1,107 followersView post →
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thalesnemo
@thalesnemo · X
@marhashtrashisu @shashiiyengar Daily Bread- Can any human body handle Gluten - Dr Rodney Ford
https://t.co/v22R15gLs6
Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/ilzYZgbVx7
https://t.co/TrMpytwrvM
Jan 10, 2024 · 2 likes · 1 share · 1,107 followersView post →
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thalesnemo
@thalesnemo · X
@lindy_lou_j @Sayers_MA Zonulin, regulation of tight junctions, and autoimmune diseases
https://t.co/ilzYZgbVx7
New-onset celiac disease in children during COVID-19 pandemic
https://t.co/8Ik8cDniZr
Risk of autoimmune diseases in patients with COVID-19 https://t.co/ZSfpWwHa9o. https://t.co/8Lk16db7vd
The video discusses how emotional states can influence gut bacteria, increase intestinal permeability, and contribute to acne through systemic inflammation, highlighting the importance of gut microbiome and probiotics…
This video explains what leaky gut is, its causes, symptoms, and how it affects autoimmune diseases. Learn about the role of tight junctions, zonulin, and dietary factors in managing and healing leaky gut for improved…
@alexflorias @rightwingnutrs @JoshRainerGold Modern breads and ALL GRAIN PRODUCTS are an acute GI TOXIN and liver toxin too!
Why wheat and grains are toxic to humans
Dr William Davis
https://t.co/S7Cf7og7kJ
Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/ilzYZgbVx7 https://t.co/hPoV3dNVle
Aug 17, 2025 · 1 like · 1,107 followersView post →
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thalesnemo
@thalesnemo · X
@socialrallyceo @GigaBasedDad No it’s the GLUTEN !
Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/ilzYZgbVx7
https://t.co/wt63Zq7KVR
https://t.co/2yBDV8M1Sh
https://t.co/BYMDmE2cGu
Jul 28, 2025 · 1 like · 1,107 followersView post →
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thalesnemo
@thalesnemo · X
@GigaBasedDad Why wheat and grains are toxic to humans
Dr William Davis
https://t.co/S7Cf7og7kJ
Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/ilzYZgbVx7
https://t.co/v22R15gLs6
https://t.co/TrMpytwrvM https://t.co/EFRymkeUth
#Carnivore #Ernährung und Leaky gut
Carnivore College
https://t.co/NAsvYSHJdA
#Gluten #Protein #Zonulin #InnereEntzündungen #Balaststoffe
Feb 24, 2025 · 1 like · 6,651 followersView post →
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thalesnemo
@thalesnemo · X
@mjdgehri @robertlufkinmd @CaryKelly11 Grains are a GI toxin !
"Pure, white and deadly" by John Yudkin and Robert H Lustig- https://t.co/VbKqZ8owqa
https://t.co/v22R15hjhE
Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/ilzYZgbVx7
@Manderville_RD Daily Bread- Can any human body handle Gluten - Dr Rodney Ford
https://t.co/v22R15gLs6
Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/ilzYZgbVx7
@LucianTritt @terkelsenn68 @SamaHoole Why wheat and grains are toxic to humans
Dr William Davis
https://t.co/S7Cf7og7kJ
Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/ilzYZgbVx7 https://t.co/fOIq8sjopX
@9250Robin @nishantkr_18 All grains are toxic whether there any symptoms!
Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/ilzYZgbVx7
@Autisticatheis3 @ThePOTSPostman ALL GRAINS ARE TOXIC !
Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/ilzYZgbVx7
@NorCalRoe78 @CaryKelly11 But ALL GRAINS ARE A TOXIN TO THE HUMAN GI TRACK!
Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/ilzYZgbVx7
https://t.co/v22R15gLs6
@robertlufkinmd ANY GLUTEN IS TOXIC !
The level 20 ppm aka a crumb !
Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/AtDATFmgmP
https://t.co/VKgMaFnVng
@ajaydayal1 @shashiiyengar ALL GRAINS ARE TOXIC TO THE HUMAN GI TRACK ! Just stop eating that rubbish ! ➡️ Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/ilzYZgbVx7 ➡️ https://t.co/v22R15gLs6 ➡️ https://t.co/8Ik8cDniZr
RT @thalesnemo: @ElieJarrougeMD Grains have ZERO place in the human diet irrespective of any overt symptoms!
Zonulin, regulation of tight…
Feb 18, 2024 · 1 share · 1,418 followersView post →
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thalesnemo
@thalesnemo · X
@ElieJarrougeMD Grains have ZERO place in the human diet irrespective of any overt symptoms!
Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/ilzYZgbVx7
Feb 18, 2024 · 3 likes · 1 share · 1,107 followersView post →
T
thalesnemo
@thalesnemo · X
@BiggestComeback @1718106J @Koltaine11 ALL GRAINS ARE A TOXIN TO
THE HUMAN GI TRACK!
Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/ilzYZgbVx7 ➡️ https://t.co/v22R15gLs6
eagleeye192020 Proud Hindu &Indian-Modi Ka Parivar
@eagleeye192020 · X
RT @thalesnemo: @marhashtrashisu @shashiiyengar Daily Bread- Can any human body handle Gluten - Dr Rodney Ford
https://t.co/v22R15gLs6
Zo…
Jan 11, 2024 · 1 share · 1,373 followersView post →
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thalesnemo
@thalesnemo · X
@marhashtrashisu @shashiiyengar Daily Bread- Can any human body handle Gluten - Dr Rodney Ford
https://t.co/v22R15gLs6
Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/ilzYZgbVx7
https://t.co/TrMpytwrvM
Jan 10, 2024 · 2 likes · 1 share · 1,107 followersView post →
T
thalesnemo
@thalesnemo · X
@shashiiyengar All grains are a human GI toxin unfit for human consumption!
Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/ilzYZgbVx7
https://t.co/v22R15gLs6
@shashiiyengar You did not listen carefully to what the video had out lined . Once the body gets triggered by WHEAT the proteins of other grains ARE SIMILAR to mimic the same type of reactions . ➡️ Zonulin, regulation of tight junctions, and autoimmune diseases
https://t.co/ilzYZgbVx7
@aCarnivoreDiet Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/ilzYZgbVx7 Associations with tight junction genes PARD3 and MAGI2 in Dutch patients point to a common barrier defect for coeliac disease and ulcerative colitis.
https://t.co/Zfx2EX5gOJ
Aug 13, 2023 · 1 like · 1,107 followersView post →
KT
KanLi NDn - Holistic Approach, Learn & Teach
@CalinNadasan · X
RT @thalesnemo: @markeatsmeat Zonulin, regulation of tight junctions, and autoimmune diseases-Alessio Fasano
https://t.co/ilzYZgbVx7 ➡️
htt…
Aug 9, 2023 · 1 like · 1 share · 1,107 followersView post →
T
thalesnemo
@thalesnemo · X
@lindy_lou_j @Sayers_MA Zonulin, regulation of tight junctions, and autoimmune diseases
https://t.co/ilzYZgbVx7
New-onset celiac disease in children during COVID-19 pandemic
https://t.co/8Ik8cDniZr
Risk of autoimmune diseases in patients with COVID-19 https://t.co/ZSfpWwHa9o. https://t.co/8Lk16db7vd
@saaiyer Zonulin, regulation of tight junctions, and autoimmune diseases Alessio Fasano
https://t.co/ilzYZgbVx7 ➡️ Daily Bread- Can any human body handle Gluten - Dr Rodney Ford
https://t.co/v22R15gLs6 ➡️ Peter Ballerstedt-When Protein is not protein [1:04]
https://t.co/q3fLEHXRHN
RT @wellbalanceND: “There are at least 50 toxic epitopes in gluten peptides exerting cytotoxic, immunomodulatory, and gut permeating activi…
Nov 14, 2021 · 2 shares · 1,200 followersView post →
MD
Michelle Dowker
@wellbalanceND · X
RT @wellbalanceND: “There are at least 50 toxic epitopes in gluten peptides exerting cytotoxic, immunomodulatory, and gut permeating activi…
Nov 14, 2021 · 2 shares · 5,568 followersView post →
MD
Michelle Dowker
@wellbalanceND · X
“There are at least 50 toxic epitopes in gluten peptides exerting cytotoxic, immunomodulatory, and gut permeating activities”
Zonulin, regulation of tight junctions, and autoimmune diseases https://t.co/Ddgh1fEa5c
Oct 8, 2021 · 6 likes · 2 shares · 5,568 followersView post →
MS
M Susan
@MSmeowsie · X
@CheriJacobus @LaurelCoons
You may find this (tedious) read interesting/helpful
I started with gut health/candida/autoimmune disease research ended up here
@ScepticalDoctor Grains are toxic ! Grains are anti-nutrients! Daily Bread- Can any human body handle Gluten - Dr Rodney Ford
https://t.co/jFLs53XJhV Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/ilzYZgbVx7
Zonulin, regulation of tight junctions, and autoimmune diseases https://t.co/XiBE6nkGud
May 2, 2021 · 1 like · 10,746 followersView post →
T
thalesnemo
@thalesnemo · X
@Freewheal @fleroy1974 Pure rubbish! Humans have no ability to fully digest grains. 1️⃣ Daily Bread- Can any human body handle Gluten - Dr Rodney Ford
https://t.co/ltPpj5781y️⃣ Zonulin, regulation of tight junctions, and autoimmune diseases
Alessio Fasano
https://t.co/ilzYZgbVx7
@AlexFerentinos7 @drjamesdinic It is indigestible, triggers auto-immunity through binding to glycoproteins, and is the strongest zonulin stimulator... Zonulin stimulators open holes in your intestines.
https://t.co/jrdlR6RfDH
"Zonulin, regulation of tight junctions, and autoimmune diseases"
... J, Nowak-Węgrzyn A. Intestinal permeability in children with food ... doi: 10.1111/j. 1749-6632.2012.06538.x k. Kauki Mori , Y Nakagawa, H Ozaki ...
doi: 10.1111/j. 1749-6632.2012.06538.x k. Kauki Mori , Y Nakagawa, H Ozaki ... x. Oleh itu BERHATI-HATILAH dengan TIPU MUSLIHAT mereka yang kita tidak ...
পুষ্টিবিদ এ বি সিদ্দিক (@nutritionistabsiddique) • Facebook
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doi:10.1111/j. 1749-6632.2012.06538.x Ohlsson, B.; Orho-Melander, M.; Nilsson, P.M. Higher Levels of Serum Zonulin May Rather Be Associated with Increased ...
... x beli dah kot mayonis. Dah la aku ni hantu garlic. Peminat nasi arab ... doi: 10.1111/j. 1749-6632.2012.06538.x k. Kauki Mori , Y Nakagawa, H Ozaki ...
Journal: Annals of the New York Academy of Sciences, 1258(1), 25–33. https://doi.org/10.1111/j.1749-6632.2012.06538.x 3. Mu, Q., Kirby, J., Reilly, C. M., & Luo ...
Role of Gut Microbiota in Cardiovascular Diseases | PDF ...
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25-33 [PMID: 22731712 DOI: 10.1111/j.1749-6632.2012.06538.x] 30 Nouri M, Bredberg A, Weström B, Lavasani S. Intestinal barrier dysfunction develops at the ...
WJG-28-449 gastroenterology | PDF | Epigenetics | Regulation Of ...
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... 10.1111/j.1749-6632.2012.06538.x] 46 Jauregi-Miguel A, Santin I, Garcia-Etxebarria K, Olazagoitia-Garmendia A, Romero-Garmendia I, Sebastian-delaCruz M ...