Front Genet October 2012 PMID 22833755

What is Aging?

Michael R Rose, Thomas Flatt, Joseph L Graves, Lee F Greer, Daniel E Martinez, Margarida Matos, Laurence D Mueller, Robert J Shmookler Reis, Parvin Shahrestani

Mentions

90
Peak: 14 in Dec 2025
across 6 sources since Nov 2014

Extended reach

3,367,345
potential audience

Total likes

24,934

Video views

3,344,444

Mentions per month

Nov 2014 – Jan 2026

Where it's discussed

  • Bluesky48 posts
  • X / Twitter24 posts
  • Facebook12 posts
  • News3 articles
  • YouTube2 videos
  • Reddit1 posts

AI synopsis

What people are saying

The overall sentiments demonstrate a high interest in understanding aging, exemplified by posts asking 'What is aging?' and referencing ongoing scientific debates about its causes and definitions, while tone varies from curiosity to humor, reflecting varied levels of engagement and perceived significance of the topic.

AgreementModerate agreement

Most discussions show curiosity and some support for exploring what aging is, with a few posts questioning basic assumptions or highlighting the complexity of the topic.

InterestHigh interest

Many posts express high curiosity, with questions like 'What is aging?' and references to scientific debates, indicating strong interest.

EngagementModerate engagement

Posts involve diverse perspectives, including personal observations and scientific inquiries, pointing to moderate engagement levels.

ImpactModerate impact

The discussions touch on the fundamental nature of aging, societal implications, and scientific research, suggesting a moderate but meaningful impact.

Abstract in brief

  • AgingBR is a platform focused on providing information and resources related to aging and elderly care in Brazil.
  • It aims to support seniors, caregivers, and families by sharing relevant news, health tips, and social programs.
  • The platform seeks to improve the quality of life for older adults through education and community engagement.]

Top posts

Most liked on X and Bluesky
muscular baby jeb lund
@mobute.bsky.social · Bluesky

what is aging but the victory of entropy, of chaos? [raises flute of beef tallow]

Oct 5, 2025 · 172 likes · 7 shares View post →
Bilu Huang
@biluhuang · X

Honored to have co-authored the chapter “What is Aging and Healthy Longevity?” as part of an International Longevity Alliance initiative. Big thanks to @ILAISRLA for the invitation and incredible work in promoting healthy longevity globally. Can’t wait to share it! https://t.co/c3382z2Wx6

Jan 10, 2026 · 18 likes · 1 share · 749 followers View post →
Helscom
@helscom · X

[me drinking three days in a row over the weekend]: i am GOD. what is aging even [me at the end of next tuesday]: wait, no

Nov 25, 2025 · 10 likes · 2,213 followers View post →
Doc Jerr
@docjerr.bsky.social · Bluesky

Dr. Jerry Goebel Most presidents are aged by threats to global peace or economic stability, but Trump has no empathy. What is aging him is the fear that the Epstein Files will be released. Keep up the pressure; demand the files! www.communitiesoftrust-jerrygoebel.com/youthadvocacy

Sep 2, 2025 · 8 likes · 1 share View post →
Khyenpa
@khyenpa · X

@IAintMadAtCha1 @JoeyFinley18 @acdmma_ @MisfitsBoxing What is aging?

Dec 21, 2025 · 6 likes · 14 followers View post →
Peter Lidsky
@LidskyPeter · X

@jpsenescence Here I am totally with @jpsenescence . We do not know what is aging and why do we age. Damage accumulation accompanies aging, but has never been demonstrated to be its cause. Surely, the fundamental understanding of aging will likely dive a start to the development of the cure.

Dec 10, 2025 · 5 likes · 1 share · 2,018 followers View post →

All mentions

Tribe Two
@TribeTwo2 · X

@ErnstRoets @grok what is aging this man so drastically

Jan 11, 2026 · 324 followers View post →
El señor de Bembibre
@Lampertheim2 · X

RT @biluhuang: Honored to have co-authored the chapter “What is Aging and Healthy Longevity?” as part of an International Longevity Allianc…

Jan 11, 2026 · 1 share · 960 followers View post →
Bilu Huang Aging Institute
@BiluHuangAging · X

Jan 11, 2026 · 2 likes · 58 followers View post →
Alien the Revelator
@foardeetou · X

@1whoneverknew @White_Rabbit_OG If time is not real Then what is aging?

Jan 10, 2026 · 2,293 followers View post →
Bilu Huang
@biluhuang · X

Honored to have co-authored the chapter “What is Aging and Healthy Longevity?” as part of an International Longevity Alliance initiative. Big thanks to @ILAISRLA for the invitation and incredible work in promoting healthy longevity globally. Can’t wait to share it! https://t.co/c3382z2Wx6

Jan 10, 2026 · 18 likes · 1 share · 749 followers View post →
thecrimsonhornet.bsky.social
@thecrimsonhornet.bsky.social · Bluesky

This post is not aging well. What is aging is Oregon's CFP chances.

Jan 9, 2026 View post →
Megumi Grace Kudo©️™️
@MegumiGraceKudo · X

RT @MegumiGraceKudo: What is aging? Everybody ages differently; our rate of aging depends on inherited and lifestyle favors. (by Cancer Awa…

Jan 9, 2026 · 3 shares · 586 followers View post →
LizNYNY
@liznyny · X

@MARIDL18 @cloclo39343411 @archiveskeanu What is aging him is the grey beard. I would love to see what he’d look like clean shaven with a different hairstyle that truly accentuates his good looks.

Jan 8, 2026 · 215 followers View post →
Andy Matthews
@andymatthewsmusic.bsky.social · Bluesky

Having a hard time telling what is seasonal depression, what is aging, and what is the unrelenting and unrepentant criminal actions of the government when it comes to determining why I’m so fucking miserable all the time.

Jan 5, 2026 View post →
Holly Albrecht
@dogluvr3333 · X

@Jimooskie @DavidWolfe I agree. The stress on their immune systems is what is aging them. It's a dramatic sign of what their poor bodies are going through on the inside.

Jan 4, 2026 · 2 likes · 1,138 followers View post →
Jasper Rexy π
@jasperrexy · X

@Motion_Boy_ What is aging about her, nature happens to us all. Don't age-shame anybody. To you she might be old but others she is still a Beautiful Young Lady. And moreso the baby face is still there. So leave Tiwa for crushers

Jan 3, 2026 · 140 followers View post →
Black Berry | Free Palestine
@Blackberrycalss · X

@LiberalSpamton @Foxx_nd_Inkwell @berriebombz Okay they please enlighten me, what is aging up a character that's different then a character growing up and why is it bad?

Dec 22, 2025 · 1 like · 122 followers View post →
moutainchem
@baijianjiance · X

Powder Coating Q&A (24) 24.What is aging testing? Answer: Aging testing primarily refers to thermal oxidative aging tests conducted on rubber, plastic products, electrical insulation materials, and other materials; or ventilation aging tests conducted on electronic components . https://t.co/VyE7ul09qZ

Dec 22, 2025 · 1 like · 1 followers View post →
Khyenpa
@khyenpa · X

@IAintMadAtCha1 @JoeyFinley18 @acdmma_ @MisfitsBoxing What is aging?

Dec 21, 2025 · 6 likes · 14 followers View post →
garlicbreadgawd
@garlicbreadgawd · X

@Mista_Shakur @content__hunter @YoungxSavage__ @mhidxe @QueenAnticommie “Time doesn’t exist” followed by “when” WHEN what? If there’s no time there is no past, present or future? What is aging? What is a process? What is speed? What is physics? None of these exist without time yet you acknowledge all of them. Do not run from reality.

Dec 21, 2025 · 147 followers View post →
Maria
@measieee · X

@alexbruesewitz @LauraLoomer The irony of Loomer is that she uses fillers and Botox and rarely smiles because she doesn’t want to age but the fillers and Botox and lack of laughter lines is what is aging her… she’s only 32 but already looks mid 40’s.

Dec 16, 2025 · 4 likes · 719 followers View post →
Asa Soo
@asasoo22 · X

@brockpierson Millennial forever young generation Gen Z age like milk my sister is 22 but look like 28 or maybe 30 dues to stress and world nowadays, some Gen X is quite youthful, like me i look like 25 but I,m 32 now 2026 will be 33 because Gen Y redefined what is aging i think because of

Dec 15, 2025 · 3,851 followers View post →
Eva Lewarne
@evalewarne.bsky.social · Bluesky

What is aging? open.substack.com/pub/evalewar...

Dec 15, 2025 · 1 like View post →
John Razimus Hughston
@razimus · X

@its_The_Dr All these zlennials asking “what is aging?” You’ll find out, you too one day will be a super old fart and alennials will again ask why your old ass looks so old

Dec 15, 2025 · 3,885 followers View post →
Wilma Mankiller
@justlikeevyn.bsky.social · Bluesky

What is aging? I need a nap. I don't want to smoke anymore. I'm practically done with eating cheese and meat. I have been leaving almost half a glass of alcohol on the table. I don't like cold drinks anymore and will get irritated at ice water with my food. I'm only 27.

Dec 14, 2025 · 1 like · 1 share View post →
Gregory White
@tenniscookgrw · X

RT @LidskyPeter: @jpsenescence Here I am totally with @jpsenescence . We do not know what is aging and why do we age. Damage accumulation a…

Dec 10, 2025 · 1 share · 51 followers View post →
Peter Lidsky
@LidskyPeter · X

@jpsenescence Here I am totally with @jpsenescence . We do not know what is aging and why do we age. Damage accumulation accompanies aging, but has never been demonstrated to be its cause. Surely, the fundamental understanding of aging will likely dive a start to the development of the cure.

Dec 10, 2025 · 5 likes · 1 share · 2,018 followers View post →
Pod of Inquiry
@podofinquiry · X

What is Aging?

Dec 9, 2025 · 2 likes · 13 followers View post →
ZapLoaf
@ZapLoaf · X

@GalvStudios22 What is aging?

Dec 8, 2025 · 27 followers View post →
David Claus
@dvdclaus1 · X

@Rainmaker1973 What is aging then?

Dec 6, 2025 · 1 like · 1,892 followers View post →
Lisa who used to use her last name here but deleted it:)
@amidprivilege.bsky.social · Bluesky

done on our behalf. I am thinking there must be a book on the benchmarks of aging? What is aging, what is disease? What is hereditary, what is lifestyle? So annoying that they don't know!

Nov 26, 2025 · 1 like · 1 share View post →
Lady Deim
@LadyDeim · X

@TrumpsHurricane What is aging?

Nov 26, 2025 · 340 followers View post →
Beverly Bonnie
@Beverlymaga · X

@JustJoshinNH What is aging?

Nov 25, 2025 · 914 followers View post →
Helscom
@helscom · X

[me drinking three days in a row over the weekend]: i am GOD. what is aging even [me at the end of next tuesday]: wait, no

Nov 25, 2025 · 10 likes · 2,213 followers View post →
muscular baby jeb lund
@mobute.bsky.social · Bluesky

what is aging but the victory of entropy, of chaos? [raises flute of beef tallow]

Oct 5, 2025 · 172 likes · 7 shares View post →
Zunel
@zunelhak.bsky.social · Bluesky

It should be illegal to air these "programs" on daytime TV all like "what is aging? can we stop it, or even, reverse it? The secret is this new serum..."

Oct 4, 2025 · 3 likes · 1 share View post →
Auncerra
@8auncerra.bsky.social · Bluesky

And what is aging when time isn’t linear. Obviously within appropriate boundaries. I’m just saying - past your 20s. It’s just the expression of skin and features morphing. It’s not lack. It’s not decrepitude. Turkeys are beautiful creatures too. I don’t mean that disparagingly. I’m just saying.

Sep 27, 2025 View post →
Peco
@peco-p.bsky.social · Bluesky

What is aging if not learning the places in your life wherein avoidance is the only reliable method of self-improvement

Sep 22, 2025 · 2 likes View post →
A.
@alexxaye.bsky.social · Bluesky

I think I overworked a muscle while stretching. What is aging.

Sep 8, 2025 View post →
Doc Jerr
@docjerr.bsky.social · Bluesky

Dr. Jerry Goebel Most presidents are aged by threats to global peace or economic stability, but Trump has no empathy. What is aging him is the fear that the Epstein Files will be released. Keep up the pressure; demand the files! www.communitiesoftrust-jerrygoebel.com/youthadvocacy

Sep 2, 2025 · 8 likes · 1 share View post →
Neal Novotny
@nn-50.bsky.social · Bluesky

What is aging all about??

Aug 24, 2025 · 1 like View post →
zeen
@zeen.bsky.social · Bluesky

What is aging? You cannot make your writing strokes on your intended, and those strokes are not even and sometimes yours are made in sudden. This is the aging.

Aug 14, 2025 View post →
mmmemmm.me
@mmmemmm.me · Bluesky

I feel like I can't recognize anymore what is rheumatism, what is aging, and what is just.. Something else. Tbh the whole rheumatism thing is a confusing mess to me nowadays, I do not know a life without it, so I have nothing to compare it to. I can't remember my worst pains either, I was so young.

Jul 11, 2025 · 3 likes · 1 share View post →
lobster wife
@hellohell.bsky.social · Bluesky

Like what is aging, I don't hate it in a general sense, but this sucks. I have to learn to hold my knitting differently?? Does my finger even know how long it's been doing this? Thirty odd years of knitting. I really feel like it's just being dramatic, I mean come on.

Jun 14, 2025 · 1 share View post →
BillThePony
@billthepony.bsky.social · Bluesky

What % is "aging centrist leaders unwilling to compromise or step aside"?

May 22, 2025 · 1 share View post →
Chris Michael Ward
@chrismichaelward.bsky.social · Bluesky

Today is 100 days of Trump's 2nd presidential term. Along with time, this is what is aging American voters in my opinion!

Apr 29, 2025 View post →
Charlie Kisses Big Dinners
@clementinedanger.bsky.social · Bluesky

What is aging but a return to the womb

Apr 25, 2025 · 1 like View post →
rvsehgal.bsky.social
@rvsehgal.bsky.social · Bluesky

As the body’s repair systems slow, aging speeds up. These are the final stages: stem cell loss, waste buildup, and gut imbalance.

Apr 21, 2025 View post →
Decoding Longevity
@decodinglongevity.bsky.social · Bluesky

What happens when the body can't recover anymore? The Integrative Hallmarks of Aging explain how small cracks become big problems.

Apr 20, 2025 · 1 like · 2 shares View post →
rvsehgal.bsky.social
@rvsehgal.bsky.social · Bluesky

Aging isn’t always breakdown — sometimes it’s overreaction. This post explains 4 internal changes that go from helpful to harmful.

Apr 19, 2025 · 1 like View post →
Decoding Longevity
@decodinglongevity.bsky.social · Bluesky

Aging isn’t just wear and tear. Sometimes, it’s your body’s own systems overreacting — and that causes harm.

Apr 18, 2025 · 2 shares View post →
rvsehgal.bsky.social
@rvsehgal.bsky.social · Bluesky

This one explains how aging begins deep inside our cells — in a way that’s easy to understand.

Apr 17, 2025 View post →
Decoding Longevity
@decodinglongevity.bsky.social · Bluesky

Aging starts at the cellular level — and it begins earlier than you think. In our new episode, we explore the 4 primary hallmarks that kick off the aging process inside your body.

Apr 16, 2025 · 1 like · 3 shares View post →
Decoding Longevity
@decodinglongevity.bsky.social · Bluesky

Aging starts deep in your cells — long before you see the signs. In our new episode, we explore 3 stages of biological aging: 1️⃣ Primary 2️⃣ Antagonistic 3️⃣ Integrative Start understanding your body on a whole new level.

Apr 13, 2025 · 1 like · 2 shares View post →
luco!!!!
@lucotron.bsky.social · Bluesky

one day I was playing with legos the next I was looking for a non stick frying pan what is aging

Apr 8, 2025 View post →
Anna Zabo
@amergina.bsky.social · Bluesky

What is aging?

Apr 5, 2025 · 3 likes View post →
JSCOTHREN
@bbobson.bsky.social · Bluesky

What is aging her?

Apr 2, 2025 View post →
Trevor Ford
@trevorisjoking.bsky.social · Bluesky

What is aging? I used to drink 30 cans of classic Coke a week. I could drink three and go right to bed now if I have two Coke Zeroes in a day I feel bad.

Mar 29, 2025 View post →
Justin
@justinthesky.bsky.social · Bluesky

I'm Seth Rogan? Nah, he's younger than I am. It's funny how the threat of decapitation can stop most events from happening! He can keep the alcohol, though. Maybe that's what is aging him prematurely?

Mar 29, 2025 · 2 likes · 1 share View post →
Christoph Handschin
@c-handschin.bsky.social · Bluesky

1.) What is aging? An inevitable normal biological process? A disease that can be treated or even cured? In any case, aging is one of the strongest risk factors for many (mostly chronic diseases), e.g. #cancer, #neurodegeneration and #dementia, or #cardiovascular pathologies. 2/9

Mar 28, 2025 · 1 share View post →
George3d6
@cerebralab.com · Bluesky

Break it down by country it holds true, split it on income or genetics... it holds true, filter out disease … it holds true. Somewhere, something happens, and we go from getting better at not dying to getting worse at it. That's the effect of aging. But what is aging?

Mar 11, 2025 · 1 share View post →
Memory Flashes
@camy40.bsky.social · Bluesky

Paper-thin skin peppered with brown splotches across my hand like a raised map. Always shocked: I am aging. Am I unusual? No, I find all of us are surprised that digitally nothing can prepare us for a forward-facing camera. What is aging? Privilege--not everyone gets to do it ... Privilege...

Mar 6, 2025 View post →
Garden State Zorro
@zorrox.bsky.social · Bluesky

“What is aging? To me, mortality is a manifestation of aging. It's not aging itself. It's just one of the features.” www.corememory.com/p/when-aging...

Feb 19, 2025 View post →
Kerry Gleason
@kerrygleason.bsky.social · Bluesky

What is “aging and unmonitored“ is Stephen Miller.

Feb 18, 2025 · 1 like View post →
Befekadu
@befekaduwg.bsky.social · Bluesky

What is aging? It is the buildup of error… So, with quantum computers we will be able to isolate the process which makes aging possible. www.youtube.com/shorts/TXYTp...

Dec 31, 2024 View post →
Shin Asayama
@shinasayama.bsky.social · Bluesky

"[T]he survey exposed broad disagreement on the foundational issues. What is aging? What causes it? When does it begin? What constitutes rejuvenation? ... Despite many researchers believing they understand aging, their understanding diverges considerably." academic.oup.com/pnasnexus/ar...

Dec 27, 2024 View post →
Raundre ⛰️
@raundre.bsky.social · Bluesky

What is aging, if not sexy older man TF

Dec 19, 2024 View post →
mindskipper.bsky.social
@mindskipper.bsky.social · Bluesky

What is aging? What causes it? When does it begin? doi.org/10.1093/pnas...

Dec 12, 2024 · 2 likes View post →
Benjamin Horne
@drbenjaminhorne.bsky.social · Bluesky

What is aging? Disagreements on the foundational principles of biological aging academic.oup.com/pnasnexus/ar...

Dec 4, 2024 · 3 likes View post →
Madame M
@micheome.bsky.social · Bluesky

Wow, this is wild. -> “What is aging? What causes it? When does it begin? What constitutes rejuvenation? Not only was there no consensus on these and other core questions, but none of the questions received a majority opinion”

Dec 4, 2024 · 1 like View post →
Ariel K. Frame
@arielframe.bsky.social · Bluesky

To be fair, I think they would have got closer to consensus if they had asked more specifically “what is biological aging” instead of “what is aging”

Dec 4, 2024 · 1 like View post →
Miguel Godinho Ferreira
@miguelgf.bsky.social · Bluesky

Let's start with basics - What is aging? We even fail at a consensus definition... This is fundamental to develop mechanistic assays to measure biological aging.

Dec 4, 2024 · 5 likes · 3 shares View post →
Science Blog
@scienceblog.com · Bluesky

Scientists Split on Fundamental Questions About Biological Aging A new survey reveals striking disagreement among aging researchers on basic questions like "What is aging?" and "When does it begin?" The findings suggest that even experts studying aging have dramatically different views on its…

Dec 3, 2024 View post →
0m
@transexualcore.neocities.org · Bluesky

Today I found a white hair. Not gray, completely stark white. I also found a black hair? And some that's gone really wavy? What is aging????

Oct 7, 2024 View post →
zuleikamitford.bsky.social
@zuleikamitford.bsky.social · Bluesky

and what is aging but another form of time travel...

Aug 12, 2024 · 3 likes View post →
Kylie M. Smith
@drkyliesmith.bsky.social · Bluesky

Haha that made me laugh out loud. What is aging if it’s not one humiliation after another?

Aug 3, 2024 · 2 likes View post →
LRIG.org
@lrig.org · Bluesky

What is aging: longevity startups face a key FDA obstacle #Business

Jan 22, 2019 View post →
Joseph L Graves Alan H Goodman Racism Not Race Answers To ...
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... gene, such as in the case of brown, blue, and green eye color. A ... 10.3389/fgene .2012.00134. 4. M. R. Rose, Evolutionary Biology of Aging (New ...

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Analysis of relative gene expression levels was performed using the 2[sup]−? ... doi: 10.3389/fphar.2012.00134. 23. Braconi C, Kogure T, Valeri N, Huang N ...

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10.3389/fmicb.2012.00134. Shi, L., Rosso, K. M., Clarke, T. A. ... gene clusters. The -barrel paralogs are similar in predicted size (MtrB 697aa ...

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From the Wet Lab to an issue of "Current Biology"! Senior marine ...
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Gene. 3:134. doi: 10.3389/fgene.2012.00134. P. Shahrestani, J. Quach, L.D. Mueller, M.R. Rose. 2012. Paradoxical physiological transitions from aging to ...

Jan 12, 2026 View →
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Gene. 3:134. doi: 10.3389/fgene.2012.00134. P. Shahrestani, J. Quach, L.D. Mueller, M.R. Rose. 2012. Paradoxical physiological transitions ...

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Bibhu Simkhada, Ph.D. student under Drs. Trudy Mackay and ...
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Gene. 3:134. doi: 10.3389/fgene.2012.00134. P. Shahrestani, J. Quach, L.D. Mueller, M.R. Rose. 2012. Paradoxical physiological transitions ...

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Really interesting science in this YouTube clip - 30 mins only. I have ...
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What is aging? Front. Gene. 3:134. doi: 10.3389/fgene.2012.00134. P. Shahrestani, J. Quach, L.D. Mueller, M.R. Rose.

Jan 6, 2025 View →
Michael Rose - Life Extension Scientist https://www.faculty.uci.edu ...
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Gene. 3:134. doi: 10.3389/fgene.2012.00134. P. Shahrestani, J. Quach, L.D. Mueller, M.R. Rose. 2012. Paradoxical physiological transitions ...

Feb 24, 2024 View →
Michael Rose - Facebook
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Gene. 3:134. doi: 10.3389/fgene.2012.00134. P. Shahrestani, J. Quach, L.D. Mueller, M.R. Rose. 2012. Paradoxical physiological transitions ...

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Lifespan Extension In Drosophila: A Conversation with Dr. Michael ...
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Gene. 3:134. doi: 10.3389/fgene.2012.00134. P. Shahrestani, J. Quach, L.D. Mueller, M.R. Rose. 2012. Paradoxical physiological transitions ...

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Jean R. David (1931-2021), a tribute by his students and ... - Facebook
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Gene. 3:134. doi: 10.3389/fgene.2012.00134. P. Shahrestani, J. Quach, L.D. Mueller, M.R. Rose. 2012. Paradoxical physiological transitions ...

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BioViva warmly welcomes Dr de Magalhaes to our Scientific ...
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What is aging? Front. Gene. 3:134. doi: 10.3389/fgene.2012.00134. P. Shahrestani, J. Quach, L.D. Mueller, M.R. Rose.

Jun 2, 2019 View →
I'm advertising for a PhD student on a competitive-funded PhD ...
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What is aging? Front. Gene. 3:134. doi: 10.3389/fgene.2012.00134. P. Shahrestani, J. Quach, L.D. Mueller, M.R. Rose.

May 30, 2019 View →
What is the name of the biologist who lived for 100 years?
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Gene. 3:134. doi: 10.3389/fgene.2012.00134. P. Shahrestani, J. Quach, L.D. Mueller, M.R. Rose. 2012. Paradoxical physiological transitions ...

Jul 5, 2018 View →
Why can't biological Hosts age? : r/westworld
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... internal physiological deterioration-- journal.frontiersin.org/article/10.3389/fgene.2012.00134/pdf r/Dunning–Kruger effect. [deleted]. • 9y ago.

Nov 23, 2016 View →
Jim Flanagan you said Evolution has not been observed....here is a ...
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Gene Flow Another important evolutionary force is gene flow, or the ... doi: 10.3389/fgene.2012.00134. P. Shahrestani, J. Quach, L.D. ...

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