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The discussions consistently emphasize that multiple randomized controlled trials and systematic reviews show no evidence that linoleic acid or seed oils increase inflammatory markers, as seen in posts citing research like the 2012 systematic review. The tone varies from supportive to skeptical, with some users questioning the control of variables in studies or highlighting potential health benefits, demonstrating a rigorous and nuanced debate about dietary fats and their effects.
Most discussions support the conclusion that linoleic acid does not increase inflammation, with many posts citing the systematic review indicating a consensus on this point.
The conversations display high interest, with numerous references to scientific studies, debates on mechanisms, and interpretations of research findings, reflecting active engagement.
Participants delve into details like control of variables in RCTs, mechanistic skepticism, and implications for dietary guidelines, indicating deep level of participation.
While the majority agree on the basic findings, the debates around mechanisms and broader dietary implications suggest some influence on public perceptions of seed oils and omega fats, though the direct real-world impact remains moderate.
@1_happyholistic @reallytanman Ok I checked the peer reviewed data and found that omega-6 doesn't do that. Maybe some stupid bro science blog posting wild speculation is what you had in mind? https://t.co/SJ1uUi7gqk
I agree that our current dietary omega-6 to omega-3 ratio is horrible. However I don’t know that we have proven that omega-6 is specifically “inflammatory” even though people have attempted to do so?
@logicalbaseline @hubermanlab He asked for evidence that seed oils are bad. I'm saying there is no evidence. Here's evidence AGAINST the claim that seed oils are bad Use your exquisite reading skills: https://t.co/Vu9QtQs9Aj https://t.co/KCLUuLXts7 https://t.co/tn0RGHYcn9 https://t.co/wiVwVTVaVH
@Pask218337 @cremieuxrecueil No, studies are clear. Seed oils don't increase inflammatory markers, except in youtube quack+grifter circles. https://t.co/9RBspXKkdZ https://t.co/rnKB7jJuYJ
Ending on a high note: PUFAs has a null effect or reduces inflammatory markers. Consistently. https://t.co/3SlaK0xEa5 https://t.co/bJ3yQKkjc7 https://t.co/yvUtTMeEUS https://t.co/9ZhY7Haw7P
A key aspect of a healthy diet is maintaining a positive relationship with food. Banning certain foods can lead to cravings and negatively affect your attitude towards eating. A balanced approach is essential for…
Vitamin D deficiency occurs when the body doesn't get enough vitamin D, essential for healthy bones and immune support. Factors include limited sun exposure, poor diet, medical conditions, and geographic location.
@sayajooj @ZaneDokja https://t.co/EpTNcfMMOG - linoleic acid doesnt increase inflammatory markers https://t.co/6PcGoKcpV9 - swapping SFAs in moderately hypercholesteremic individuals with PUFAs reduced LDL-C and had no effect on C-RP These are just two I found quick but there are many more.
@mats_cedervall @trikomes https://t.co/8DaMi4qyti idk how well controlled the RCTs looked at are, I doubt they control for anything relevant. "Normal" healthy individuals may just be genotypes protected from some of the worse reactions.
@Pask218337 @cremieuxrecueil No, studies are clear. Seed oils don't increase inflammatory markers, except in youtube quack+grifter circles. https://t.co/9RBspXKkdZ https://t.co/rnKB7jJuYJ
Ending on a high note: PUFAs has a null effect or reduces inflammatory markers. Consistently. https://t.co/3SlaK0xEa5 https://t.co/bJ3yQKkjc7 https://t.co/yvUtTMeEUS https://t.co/9ZhY7Haw7P
Sorry @robertlufkinmd…intake of seed oils doesn’t increase inflammation nor other potential problems, in spite yours and other novice “influencer” (https://t.co/VYKlzuqKf7) opinions. To revert back to saturated fats from non-hydrogenated plant fats would undermine the
RT @UniversOfMemory:
RT @UniversOfMemory:
RT @UniversOfMemory:
@trustsciencetm @whitley_rick @DrGaryMcGowan Effect of dietary linoleic acid on markers of inflammation in healthy persons: a systematic review of randomized controlled trials - PubMed https://t.co/uEDNoYAg4h
@logicalbaseline @hubermanlab He asked for evidence that seed oils are bad. I'm saying there is no evidence. Here's evidence AGAINST the claim that seed oils are bad Use your exquisite reading skills: https://t.co/Vu9QtQs9Aj https://t.co/KCLUuLXts7 https://t.co/tn0RGHYcn9 https://t.co/wiVwVTVaVH
@Nozzels @hubermanlab https://t.co/q0s68D2xfi https://t.co/KCLUuLXts7 https://t.co/tn0RGHYcn9 https://t.co/77nX7xi6vJ https://t.co/6Tkv16ceAO https://t.co/vmhsqtDzn4 https://t.co/luDg4KP77r
@jefferson_locke @mattyglesias https://t.co/UqAGB7f6Un
@playboyreview @concretemilk @GSpellchecker Sources: https://t.co/AbzliD9nFG https://t.co/V2yHCkoo3L https://t.co/xn7291zJtz
@LapisLazuli234 @Burning_Cards Theyre fine to be consumed, some oils are better than others for sure. PUFAs connection to inflammation doesn't seem well founded, it's better to remove animal derived products in favor of seed oils https://t.co/50oi9V3ASb
@anakreontik hier auch https://t.co/PM9rbM6zlm LA kann zur Diabetes typ 2 Prävention beitragen https://t.co/mBMzYSnoQQ
@goddeketal Googled it. "... virtually no evidence is available from randomized, controlled intervention studies among healthy, noninfant human beings to show that addition of LA to the diet increases the concentration of inflammatory markers." https://t.co/hxFJv6KYPO
@UrosMikolic Where's the evidence that oil is inflammatory? Because in human feeding studies, particularly within normal intakes, when this is tested, you don't tend to see a statistically significant effect. doi: 10.1016/j.jand.2012.03.029 doi:10.1039/c7fo00433h
@TuckerGoodrich @frog_electro @ScepticalAnna And this systematic review , meta analysis of RCTs which say linoleic acid doesn’t cause chronic inflammation https://t.co/tVzQz3M2RH
@crazieyfox @Chaddadbod the fact that you think we only have epidemiological studies on this is hilarious if not sad. When there doesn't exist any trials showing deleterious effects, it's probably a good bet they are safe. Here are some randomized control you claim don't exist. https://t.co/E65rRwdTfP
@SamaHoole @Nutri_Ben Seed oils are not inflammatory but butter is https://t.co/5w9LY3CoFh
@goddeketal If omega-6s are inflammatory (or linoleic acid since that's the n6 fat that people usually refer to as causing inflammation), why don't we see this in RCTs? https://t.co/HhLoHLzwCR https://t.co/4FadveSXCw
@robertlufkinmd Oh no! Not that inflammatory linoleic acid! https://t.co/HhLoHLzwCR https://t.co/GhYgYAnKEt
RT @ZKForTre: @AFreshLitBeacon You just embarrassed yourself in a way that is rarely seen. It’s probably time to own it. We can keep goin…
@AFreshLitBeacon You just embarrassed yourself in a way that is rarely seen. It’s probably time to own it. We can keep going, though https://t.co/3SlaK0xEa5 Actually let’s try this— do you know of a study that has shown that higher n6 Rbc content correlated with higher levels of inflammation
@raphaels7 But if you want to try, you can peruse some material: https://t.co/uNTPrOebi9 https://t.co/9Xo0DwCZKd https://t.co/0VhhmLaOK3 (Not a true clinical trial) https://t.co/gqzLerGoOw https://t.co/3SlaK0xEa5 https://t.co/j7Yoe55ID0
@raphaels7 For you, then @raphaels7 https://t.co/h6gO0YLlNq
Well, it's there now. 2012: "Effect of Dietary Linoleic Acid on Markers of Inflammation in Healthy Persons: A Systematic Review of Randomized Controlled Trials" Of course we have a more recent paper... https://t.co/93mv1P1Pgq Odd he doesn't mention that.
@AlpacaAurelius https://t.co/0BIY0vSkPF
@1_happyholistic @reallytanman Ok I checked the peer reviewed data and found that omega-6 doesn't do that. Maybe some stupid bro science blog posting wild speculation is what you had in mind? https://t.co/SJ1uUi7gqk
@bbqbaseball62 @tone_chaser_ @DrNadolsky https://t.co/50NuBzeoL0
@AFABRocky i did a 3 hour rabbit hole on this and im basically back to where i started fidilksjfsdlkfjsd but here are two studies indicating that linoleic acid consumption and inflammation aren't causally related so dont worry 2 much :3 https://t.co/80zSfv70yZ https://t.co/u9Ycl83H9O
@Conigman @LoriShemek balance of evidence I´ve seen points to no inflammatory effect of CO or LA/n6 oils in general but always happy to look at any contrary data https://t.co/5E4X8YOKF0 https://t.co/QReH36QLmp https://t.co/YlHQDX91Ok https://t.co/wG99SVoyma
@sbrown64 @GregVidua @HealthCnorlee @DietHeartNews https://t.co/EPKvkYNz1i
@DietHeartNews 2. https://t.co/EPKvkYNz1i
@The_Nutrivore @JakeMGendron @spmountjoy @1WabiSabi @RootCauseDoctor I'm impressed that he managed to find this "Rodrigues et al. recently reported that hastening of inflammation with dietary linoleic acid in a diabetic rat improved wound healing in a diabetic rat"" (random af btw) but missed something like this lol https://t.co/FXMjhE78sb
@nutrition_long @dylanarmbruste3 @The_Nutrivore Thoughts on this? Even if omega 6 is "inflammatory" (it's not), who cares if that doesn't translate into outcomes? https://t.co/FXMjhE78sb
@LoriShemek “ We conclude that virtually no evidence is available from randomized, controlled intervention studies among healthy, noninfant human beings to show that addition of LA to the diet increases the concentration of inflammatory markers.” https://t.co/t979zfqB8v
@agador_ @TuckerGoodrich Here you go sir - full paper: https://t.co/GJYBuffYMj
@TuckerGoodrich Mechanistic speculation and naturalistic fallacy running through your veins my friend. That is not science. “But PUFAs are inflammatory? I saw it in a rat study.” No, in humans they aren’t. https://t.co/PuBgqYOJG6
@The_Nutrivore @BradCohn @TuckerGoodrich How come they never cite this meta analysis? https://t.co/FXMjhE78sb
@NutritionMadeS3 Always chuckle thinking back to the closing statements of this one. https://t.co/yRJ55UFNFS Authors aren’t pulling any punches https://t.co/sAIiB1ONXW
@dylanarmbruste3 @drmarkhyman Thanks Dylan! Good pick up. Also in case someone wants data pertaining to healthy individuals I recommend reading this: https://t.co/TnexgyjhX9
He then quotes a paper that is so bad that it's actually funny. Just the usual garbage about PUFA causing inflammation (nope) https://t.co/hVLEhvTzwv https://t.co/FXMjhE78sb https://t.co/Tg1TKfdeIb and insulin resistance (nope) https://t.co/n4lkb5EQzy https://t.co/SDCHzvDnQh
@The_Nutrivore @ProfTimNoakes And before cancer tho https://t.co/VoTRR0kxRW https://t.co/nZriv2gjHG Minnesota coronary experiment and Sydney diet heart tho https://t.co/HF7SWie0W7 https://t.co/XXuJLuY4nP Inflammation tho https://t.co/FXMjhE78sb Insulin resistance tho https://t.co/VtfsWzPQmu
@Travis_Statham Effect of Dietary Linoleic Acid on Markers of Inflammation in Healthy Persons: A Systematic Review of Randomized Controlled Trials https://t.co/QJHKJEdydP
Uppmuntrade säljaren att läsa den här studien: Johnson, GH, Fritche, K. Effect of dietary linoleic acid on markers of inflammation in healthy persons: A systematic review of randomized controlled trials. J Acad Nutr Diet. 2012;112:1029-1041 https://t.co/jMR6Ecz1Dh
@foodbeforepills @TuckerGoodrich @fire_bottle @drcateshanahan @CarnivoreMD @DrPaulMason And how come interventional trials in humans LA does not increase inflammatory markers? https://t.co/ykPbIhZJZm
@MyNutritionSci @The_Nutrivore @ChrisMasterjohn "We conclude that virtually no evidence is available from randomized, controlled intervention studies among healthy, noninfant human beings to show that addition of LA to the diet increases the concentration of inflammatory markers" https://t.co/ykPbIhZJZm
RT @Nutradvance: Sys review & meta-analysis of RCTs: no evidence from human trials that additional LA
RT @Nutradvance: Sys review & meta-analysis of RCTs: no evidence from human trials that additional LA
RT @Nutradvance: Sys review & meta-analysis of RCTs: no evidence from human trials that additional LA
Sys review & meta-analysis of RCTs: no evidence from human trials that additional LA
"We conclude that virtually no evidence is available from randomized, controlled intervention studies among healthy, noninfant human beings to show that addition of LA to the diet increases the concentration of inflammatory markers" https://t.co/FXMjhE78sb https://t.co/mN990P79MC
@simongrantzero @bigfatsurprise You can learn about omega 6 fats here if you’d like. https://t.co/TnexgyjhX9
@jamminben4 @dannyketo88 2. The research doesn't support that omega 6's are pro-inlammatory. Infact, the research points to omega 6 fats being favourable for heart disease, among other things. https://t.co/Y2IfMJCCo1 https://t.co/jYIqGpuGk9 https://t.co/mpoUBInxzs https://t.co/4KWXpfuvDO
LA/PUFA and inflammatory markers: RCTs https://t.co/G5BEr8JC6y https://t.co/CvAQ449rh1 LA/PUFA has no effect. A (potential) effect on CRP is observed at stupidly high doses (>40g/day). 4/n
@oil_memes @kevinnbass @nntaleb @MatthewJDalby @_CynthiaThurlow @drcateshanahan @fire_bottle @CarnivoreMD @Microsoft Furthermore, we have studies- like actual objective evidence- which actually demonstrates a benefit to PUFA's in certain situations, like ⬇️ CBD risk. And the studies on inflammation are pretty promising too. https://t.co/Y2IfMJCCo1
RT @TrejbalChris: @med_conscience @_CynthiaThurlow Omega 6 (seed oils) - analysis of RCT's https://t.co/Y2IfMJCCo1 Sugar consumption is…
RT @TrejbalChris: @med_conscience @_CynthiaThurlow Omega 6 (seed oils) - analysis of RCT's https://t.co/Y2IfMJCCo1 Sugar consumption is…
@med_conscience @_CynthiaThurlow Omega 6 (seed oils) - analysis of RCT's https://t.co/Y2IfMJCCo1 Sugar consumption is declining while obesity ia rising. US https://t.co/WuBod3wyFV (@kevinnbass) Australia https://t.co/QjRiW6EBRI Canada https://t.co/57x9TFa647
@MacroFour @PsuedoEpiphany Again, very little evidence to support the claims of the mechanistic studies she cites. A systematic review says otherwise. Once again, a low-carb diet can be beneficial for T2DM patients. Not necessary for the general population. https://t.co/AuFF6Et1fR
RT @tednaiman: I agree that our current dietary omega-6 to omega-3 ratio is horrible. However I don’t know that we have proven that omega-6…
RT @tednaiman: I agree that our current dietary omega-6 to omega-3 ratio is horrible. However I don’t know that we have proven that omega-6…
RT @tednaiman: I agree that our current dietary omega-6 to omega-3 ratio is horrible. However I don’t know that we have proven that omega-6…
RT @tednaiman: I agree that our current dietary omega-6 to omega-3 ratio is horrible. However I don’t know that we have proven that omega-6…
I agree that our current dietary omega-6 to omega-3 ratio is horrible. However I don’t know that we have proven that omega-6 is specifically “inflammatory” even though people have attempted to do so?