PubHawk
October 2012 PMID 22892563

Exercise induces autophagy in peripheral tissues and in the brain.

Congcong He, Rhea Sumpter, Beth Levine

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Mentions

56
Peak: 13 in Apr 2019
across 5 sources since Apr 2019

Extended reach

1,020,203
potential audience

Total likes

2,774

Video views

347,100

Mentions per month

Apr 2019 – Oct 2024

Where it's discussed

  • X / Twitter35 posts
  • News9 articles
  • Facebook6 posts
  • YouTube4 videos
  • Reddit2 posts

AI synopsis

What people are saying

The discussions highlight the significance of exercise in inducing autophagy across different tissues, including the brain, with posts emphasizing its potential to improve neurodegenerative conditions and metabolic health. Words like 'impairment,' 'benefits,' and 'effects' reflect a tone of curiosity and enthusiasm, indicating an appreciation of the research's relevance for health and aging strategies.

AgreementModerate agreement

Most discussions support the idea that exercise promotes autophagy and see it as beneficial, indicated by phrases like 'exercise induces' and 'mitigating age-related decline.'

InterestNeutral interest
EngagementNeutral engagement
ImpactNeutral impact

Abstract in brief

  • Exercise triggers autophagy not only in peripheral organs like muscle, liver, pancreas, and fat but also in the brain's cerebral cortex, highlighting its widespread impact on cellular health.
  • Researchers created genetically modified mice (BCL2 AAA) that cannot induce autophagy during exercise and starvation, which led to these mice showing impaired physical performance and failure to improve glucose metabolism after exercise, indicating autophagy's vital role in metabolic health.
  • The discovery that exercise induces brain autophagy raises questions about whether this process contributes to exercise's protective effects against neurodegenerative diseases, enhances adult neurogenesis, and improves cognitive functions.
Read the full abstract

Top posts

Most liked on X and Bluesky
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

Exercise induces autophagy in peripheral tissues and in the brain https://t.co/4n3B0szOGA

Apr 14, 2019 · 76 likes · 13 shares · 291,371 followers View post →
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

Exercise induces autophagy in peripheral tissues and in the brain https://t.co/1iWLVj1yIC

Oct 7, 2024 · 52 likes · 11 shares · 291,371 followers View post →
Hábitos 5 punto 0
@Habitos5punto0 · X

El ejercicio induce autofagia en tejidos periféricos y cerebro: https://t.co/yXLRVs5fhg Ejercicio, autofagia y apoptosis https://t.co/3Adk0mSibf Mitofagia en personas mayores: efectos del ejercicio https://t.co/2leVmtuKR0 Autofagia e intensidad de ej https://t.co/5dp4DAS7MJ

Mar 4, 2022 · 14 likes · 6 shares · 33,644 followers View post →
Ritz Asirot, MD, ABIHM
@DrAsirot · X

He C, Sumpter R Jr, Levine B. Exercise induces autophagy in peripheral tissues and in the brain. Autophagy. 2012 Oct;8(10):1548-51. doi: 10.4161/auto.21327. Epub 2012 Aug 15. PMID: 22892563; PMCID: PMC3463459.

Nov 28, 2021 · 1 like · 446 followers View post →
ResilientDad | Optimal Health By Nature
@ResilientDad · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/1iWLVj1yIC

Oct 7, 2024 · 11 shares · 13,230 followers View post →
Holtz
@Biorealism · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/4n3B0szOGA

Apr 19, 2019 · 13 shares · 8,885 followers View post →

All mentions

Dino
@dino3355 · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/1iWLVj1yIC

Oct 7, 2024 · 11 shares · 128 followers View post →
Andrei Ilnitski
@AndrIlnitski · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/1iWLVj1yIC

Oct 7, 2024 · 11 shares · 425 followers View post →
klamka
@pustaera · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/1iWLVj1yIC

Oct 7, 2024 · 11 shares · 519 followers View post →
Enrique Manzulli
@e_manfitnesss · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/1iWLVj1yIC

Oct 7, 2024 · 11 shares · 40 followers View post →
_MCRicardo_
@_MCRicardo_ · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/1iWLVj1yIC

Oct 7, 2024 · 11 shares · 1,965 followers View post →
Kim Mello
@KMello314 · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/1iWLVj1yIC

Oct 7, 2024 · 11 shares · 512 followers View post →
Wiley Long
@WileyLong · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/1iWLVj1yIC

Oct 7, 2024 · 11 shares · 1,465 followers View post →
Dr. Olivia
@olivchen777 · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/1iWLVj1yIC

Oct 7, 2024 · 11 shares · 470 followers View post →
aintgonnaworrynomore
@aintgonnaworry1 · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/1iWLVj1yIC

Oct 7, 2024 · 11 shares · 4,487 followers View post →
DrDarrellDeMello
@DarrellMello · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/1iWLVj1yIC

Oct 7, 2024 · 11 shares · 6,337 followers View post →
ResilientDad | Optimal Health By Nature
@ResilientDad · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/1iWLVj1yIC

Oct 7, 2024 · 11 shares · 13,230 followers View post →
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

Exercise induces autophagy in peripheral tissues and in the brain https://t.co/1iWLVj1yIC

Oct 7, 2024 · 52 likes · 11 shares · 291,371 followers View post →
Xavier Gonzalez
@fxxxavierrr · X

RT @AAlos40: El ejercicio induce autofagia en tejidos periféricos y cerebro: https://t.co/yXLRVs5fhg Ejercicio, autofagia y apoptosis http…

Apr 16, 2022 · 6 shares · 207 followers View post →
Osmel Hernandez
@osmeloxs · X

RT @AAlos40: El ejercicio induce autofagia en tejidos periféricos y cerebro: https://t.co/yXLRVs5fhg Ejercicio, autofagia y apoptosis http…

Mar 4, 2022 · 6 shares · 293 followers View post →
Juan Garabeti
@JGarabeti · X

RT @AAlos40: El ejercicio induce autofagia en tejidos periféricos y cerebro: https://t.co/yXLRVs5fhg Ejercicio, autofagia y apoptosis http…

Mar 4, 2022 · 6 shares · 134 followers View post →
Negrita
@Makana20201 · X

RT @AAlos40: El ejercicio induce autofagia en tejidos periféricos y cerebro: https://t.co/yXLRVs5fhg Ejercicio, autofagia y apoptosis http…

Mar 4, 2022 · 6 shares · 28 followers View post →
Marina
@cansada11869 · X

RT @AAlos40: El ejercicio induce autofagia en tejidos periféricos y cerebro: https://t.co/yXLRVs5fhg Ejercicio, autofagia y apoptosis http…

Mar 4, 2022 · 6 shares · 207 followers View post →
Luis Alonso
@luis_alonso_g · X

RT @AAlos40: El ejercicio induce autofagia en tejidos periféricos y cerebro: https://t.co/yXLRVs5fhg Ejercicio, autofagia y apoptosis http…

Mar 4, 2022 · 6 shares · 73 followers View post →
Hábitos 5 punto 0
@Habitos5punto0 · X

El ejercicio induce autofagia en tejidos periféricos y cerebro: https://t.co/yXLRVs5fhg Ejercicio, autofagia y apoptosis https://t.co/3Adk0mSibf Mitofagia en personas mayores: efectos del ejercicio https://t.co/2leVmtuKR0 Autofagia e intensidad de ej https://t.co/5dp4DAS7MJ

Mar 4, 2022 · 14 likes · 6 shares · 33,644 followers View post →
Ritz Asirot, MD, ABIHM
@DrAsirot · X

He C, Sumpter R Jr, Levine B. Exercise induces autophagy in peripheral tissues and in the brain. Autophagy. 2012 Oct;8(10):1548-51. doi: 10.4161/auto.21327. Epub 2012 Aug 15. PMID: 22892563; PMCID: PMC3463459.

Nov 28, 2021 · 1 like · 446 followers View post →
Bernie
@miseenplace86 · X

Exercise induces autophagy in peripheral tissues and in the brain https://t.co/NKdWuUr7Hh

Mar 29, 2021 · 118 followers View post →
HealthPimp | Healthcare Marketing & Design
@Healthpimp1 · X

https://t.co/xeh9PGhnhh - Exercise induces autophagy in peripheral tissues and in the brain - submitted by /u/empyreandreams [link] [comments] - #fitness #skincare and #weightloss https://t.co/8Ceww2HJxV

Nov 12, 2020 · 23 followers View post →
Holtz
@Biorealism · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/4n3B0szOGA

Apr 19, 2019 · 13 shares · 8,885 followers View post →
Michael Arthur
@Fenris813 · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/4n3B0szOGA

Apr 17, 2019 · 13 shares · 90 followers View post →
Boris Dufournet MD
@BDufournet · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/4n3B0szOGA

Apr 15, 2019 · 13 shares · 355 followers View post →
StoicTrader
@StoicTrader1 · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/4n3B0szOGA

Apr 15, 2019 · 13 shares · 662 followers View post →
laili
@laili_lai · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/4n3B0szOGA

Apr 15, 2019 · 13 shares · 68 followers View post →
Paul Pajo
@pageman · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/4n3B0szOGA

Apr 15, 2019 · 13 shares · 4,441 followers View post →
post scriptum
@psipika · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/4n3B0szOGA

Apr 15, 2019 · 13 shares · 390 followers View post →
The Dastardly One
@digitaltrav · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/4n3B0szOGA

Apr 15, 2019 · 13 shares · 182 followers View post →
Keto-meatheals
@orangebobevil · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/4n3B0szOGA

Apr 15, 2019 · 13 shares · 1,741 followers View post →
Jeff Andora |
@Jeffandora · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/4n3B0szOGA

Apr 15, 2019 · 13 shares · 953 followers View post →
Dave Grawoig, Ph.D.
@grawoig · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/4n3B0szOGA

Apr 15, 2019 · 13 shares · 6,547 followers View post →
Karageorgos
@Karageorgos15 · X

RT @Mangan150: Exercise induces autophagy in peripheral tissues and in the brain https://t.co/4n3B0szOGA

Apr 14, 2019 · 13 shares · 611 followers View post →
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

Exercise induces autophagy in peripheral tissues and in the brain https://t.co/4n3B0szOGA

Apr 14, 2019 · 76 likes · 13 shares · 291,371 followers View post →