Effect of age on atherogenicity of LDL and inflammatory markers in healthy women.

Abstract in brief

• The study found that in healthy women aged 30-79, markers of LDL atherogenicity (such as oxidized LDL and smaller LDL particle size) and inflammatory markers (like CRP, TNF, and IL6) tend to increase with age, especially after age 60.
• Although total cholesterol increases up to middle age then decreases, the inflammatory and oxidized LDL markers show a more consistent age-related rise, suggesting these may be better indicators of coronary artery disease risk.
• The findings support the idea that LDL atherogenicity and inflammation are important factors in cardiovascular risk assessment, potentially more informative than traditional risk factors like total cholesterol or smoking.]