Reduction in inappropriate therapy and mortality through ICD programming.
Arthur J Moss, Claudio Schuger, Christopher A Beck, Mary W Brown, David S Cannom, James P Daubert, N A Mark Estes, Henry Greenberg, W Jackson Hall, David T Huang, Josef Kautzner, Helmut Klein, Scott McNitt, Brian Olshansky, Morio Shoda
December 2012 N Engl J MedSynopsis of Social media discussions
The discussions highlight the study's confirmation of improved ICD programming methods, mentioning trials like MADIT-RIT and PREPARE that showed reductions in inappropriate shocks. The tone and choice of words reflect a recognition of the research’s potential to impact clinical guidelines and patient outcomes, emphasizing its importance and relevance.
Agreement
Strong agreementMost discussions recognize the article's findings as significant, referencing well-known studies like MADIT-RIT and emphasizing the benefits of programming strategies in reducing inappropriate therapies.
Interest
High level of interestThe discussions show high interest, with posters referencing specific trial names and implications, indicating engagement with the research details.
Engagement
Moderate level of engagementWhile some users discuss the technical aspects and clinical implications, the overall engagement appears thoughtful but not deeply personal or transformative.
Impact
High level of impactParticipants believe the publication could influence clinical practices broadly, using words like 'significant', 'reductions', and 'crucial' to highlight its importance.
Social Mentions
YouTube
3 Videos
12 Posts
2 Posts
Blogs
4 Articles
News
15 Articles
Metrics
Video Views
872
Total Likes
28
Extended Reach
4,891
Social Features
36
Timeline: Posts about article
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Posts referencing the article
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RT @DrJasonAndrade: Recall, MADIT-RIT (https://t.co/u6gLQkAT9m), PREPARE (https://t.co/lV8VqDeEfN) and ADVANCE-III (https://t.co/fmLOx1jjd6…
view full postOctober 20, 2021
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Edmond Cronin
@dredcronin (Twitter)We #EPeeps are all familiar with MADIT-RIT, which compared conventional programming with high rate and long detection duration programming in primary prevention ICDs. https://t.co/JcEKD6fjaj This showed a reduction in inappropriate shocks with either strategy vs conventional 2/ https://t.co/HaWZnjmNM5
view full postFebruary 6, 2019
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Abstract Synopsis
- The study found that programming implantable cardioverter-defibrillators (ICDs) with high-rate or delayed therapy settings significantly reduced inappropriate shocks and pacing, leading to lower mortality rates compared to conventional programming.
- Over an average follow-up of 14 years, both high-rate and delayed programming approaches showed hazard ratios of about 0.21 to 0.56 for inappropriate therapy and 0.45 to 0.56 for overall death, indicating substantial benefits.
- There were no notable differences in procedure-related adverse events between the different programming strategies, suggesting these methods are both effective and safe.

Cesar Bonilla
@cesarbos (Twitter)