CMAJ March 2013 PMID 23184849

Grapefruit-medication interactions: forbidden fruit or avoidable consequences?

David G Bailey, George Dresser, J Malcolm O Arnold

Mentions

125
Peak: 41 in Dec 2025
across 9 sources since Mar 2013

Extended reach

181,544
potential audience

Total likes

464

Video views

16,064

Mentions per month

Mar 2013 – Dec 2025

Where it's discussed

  • TikTok34 posts
  • Facebook29 posts
  • News23 articles
  • X / Twitter18 posts
  • Blogs10 articles
  • Instagram6 posts
  • Bluesky2 posts
  • YouTube2 videos
  • LinkedIn1 posts

AI synopsis

What people are saying

Many posts reinforce the article's message that grapefruit can interfere with certain medications, with phrases like 'dangerous interactions' and 'avoidable consequences.' The tone varies from cautionary to inquisitive, with detailed references to specific drug classes such as statins and calcium channel blockers, reflecting a general consensus on the importance of awareness but moderate overall influence on clinical practice or policy.

AgreementModerate agreement

Most discussions acknowledge the risks associated with grapefruit and medications, emphasizing caution and validation of the article's warnings.

InterestHigh interest

The topics generated high interest, especially around specific medication interactions and health warnings, indicating curiosity among readers.

EngagementModerate engagement

There are some thoughtful comments and references to sources, showing a moderate level of deep engagement with the subject.

ImpactModerate impact

While some discussions stress the importance of awareness, overall, the impact appears moderate, mainly influencing individual precautions rather than broader policy change.

Abstract in brief

  • The text discusses how grapefruit can cause dangerous interactions with certain medications, which may lead to harmful health effects.
  • It emphasizes that grapefruit is often considered a "forbidden fruit" because of its ability to interfere with how some drugs are processed in the body.
  • The article likely advises patients to avoid consuming grapefruit when taking specific medications to prevent avoidable health risks.]

Top posts

Most liked on X and Bluesky
青島周一
@syuichiao89 · X

こういう総説、地味に大事だよなあ。やはり横道なクリニカルクエスチョンに対する自分なりの答えはしっかり持っておきたい。 Grapefruit-medication interactions: forbidden fruit or avoidable consequences? - PubMed - NCBI https://t.co/vbbd7SALIH

Dec 20, 2019 · 15 likes · 3 shares · 8,605 followers View post →
Miss Cromatina
@MissCromatina · X

@CloudOfUniverse

Sep 14, 2020 · 12 likes · 2 shares · 30,737 followers View post →
Miss_Zelda
@pantieprincess4 · X

Bailey, D., Dresser, G. and Arnold, J., 2013. Grapefruit-medication interactions: Forbidden fruit or avoidable consequences?. Canadian Medical Association Journal, 185(4), pp.309-316.

Nov 10, 2020 · 10 likes · 1 share · 83,488 followers View post →
Integral Answers
@integralanswers.bsky.social · Bluesky

11A/ For more in-depth information, refer to these academic sources: •Grapefruit–medication interactions: Forbidden fruit or avoidable consequences? pmc.ncbi.nlm.nih.gov/articles/PMC... •Grapefruit juice–drug interactions: pmc.ncbi.nlm.nih.gov/articles/PMC...

Mar 24, 2025 · 10 likes · 3 shares View post →
IntegralAnswers
@IntegralAnswers · X

11A/ For more in-depth information, refer to these academic sources: •Grapefruit–medication interactions: Forbidden fruit or avoidable consequences? https://t.co/W6VR8iwV4K •Grapefruit juice–drug interactions: https://t.co/6GsWq1zHui

Mar 24, 2025 · 3 likes · 1 share · 8,610 followers View post →
matrix
@matrix____ · X

グレープフルーツには薬品の分解を阻害する成分があり、一部の薬品の効力を増強したり弱めたりします。 https://t.co/wI21Tk7hkp https://t.co/HxTaaUTozT Grapefruit–medication interactions: Forbidden fruit or avoidable consequences? https://t.co/3e4bQ0lHJD

Sep 24, 2021 · 1 like · 2,857 followers View post →

All mentions

Capybaron Goldstein
@goldstein.bsky.social · Bluesky

Source: Appendix to: Bailey DG, Dresser G, Arnold JMA. Grapefruit and medication interactions: forbidden fruit or avoidable consequences? CMAJ 2012; DOI:10.1503/cmaj.120951. Copyright © 2012 Canadian Medical Association or its licensors

May 30, 2025 · 1 like View post →
Dr. rer. nat. W. Meier-Augenstein, FRSC
@WolfmannotJack · X

RT @IntegralAnswers: 11A/ For more in-depth information, refer to these academic sources: •Grapefruit–medication interactions: Forbidden fr…

Mar 25, 2025 · 1 share · 3,898 followers View post →
Integral Answers
@integralanswers.bsky.social · Bluesky

11A/ For more in-depth information, refer to these academic sources: •Grapefruit–medication interactions: Forbidden fruit or avoidable consequences? pmc.ncbi.nlm.nih.gov/articles/PMC... •Grapefruit juice–drug interactions: pmc.ncbi.nlm.nih.gov/articles/PMC...

Mar 24, 2025 · 10 likes · 3 shares View post →
IntegralAnswers
@IntegralAnswers · X

11A/ For more in-depth information, refer to these academic sources: •Grapefruit–medication interactions: Forbidden fruit or avoidable consequences? https://t.co/W6VR8iwV4K •Grapefruit juice–drug interactions: https://t.co/6GsWq1zHui

Mar 24, 2025 · 3 likes · 1 share · 8,610 followers View post →
Alexis Avila
@LuisAlexisRam13 · X

¿Por qué el JUGO DE TORONJA representa un riesgo al combinarlo con ciertos medicamentos como estatinas y bloqueadores de canales de calcio (Atorvastatina, Nifedipino)? https://t.co/Lw5LOObSJP https://t.co/p17SN7wX6z

May 9, 2024 · 1 like · 82 followers View post →
H2Ito
@H2Ito · X

Grapefruit–medication interactions: Forbidden fruit or avoidable consequences? https://t.co/xnAS6DQeFg - Ask your personal physician, pharmacist about the drug-interactions with your specific medications.

Sep 28, 2021 · 218 followers View post →
matrix
@matrix____ · X

グレープフルーツには薬品の分解を阻害する成分があり、一部の薬品の効力を増強したり弱めたりします。 https://t.co/wI21Tk7hkp https://t.co/HxTaaUTozT Grapefruit–medication interactions: Forbidden fruit or avoidable consequences? https://t.co/3e4bQ0lHJD

Sep 24, 2021 · 1 like · 2,857 followers View post →
オルー
@ore_orue · X

ヘイ Grapefruit–medication interactions: Forbidden fruit or avoidable consequences? | CMAJ https://t.co/6eOSEtOW7X

Sep 21, 2021 · 869 followers View post →
marimedication
@marimedication · X

source:Bailey, D., Dresser, G., & Arnold, J. (2013, March 5). Grapefruit-medication interactions: Forbidden fruit or avoidable consequences? Retrieved January 15, 2021, from https://t.co/rIZebJuFD7

Mar 6, 2021 · 1 followers View post →
harry nolan
@harrynolan2 · X

RT @pantieprincess4: Bailey, D., Dresser, G. and Arnold, J., 2013. Grapefruit-medication interactions: Forbidden fruit or avoidable consequ…

Nov 10, 2020 · 1 share · 10 followers View post →
Miss_Zelda
@pantieprincess4 · X

Bailey, D., Dresser, G. and Arnold, J., 2013. Grapefruit-medication interactions: Forbidden fruit or avoidable consequences?. Canadian Medical Association Journal, 185(4), pp.309-316.

Nov 10, 2020 · 10 likes · 1 share · 83,488 followers View post →
Dr. Jiraiya Gōketsu
@DrFleshAndBone · X

RT @MissCromatina: @CloudOfUniverse

Sep 14, 2020 · 2 shares · 1,846 followers View post →
Marco Tapia Maltos
@marcvs_avrelivs · X

RT @MissCromatina: @CloudOfUniverse

Sep 14, 2020 · 2 shares · 3,232 followers View post →
Miss Cromatina
@MissCromatina · X

@CloudOfUniverse

Sep 14, 2020 · 12 likes · 2 shares · 30,737 followers View post →
コータロー@薬剤師
@intolerant_man3 · X

グレープフルーツと薬の相互作用について調べて見つけた文献 わかりやすくて言いたいことも書いてていいと思う Grapefruit–medication interactions: Forbidden fruit or avoidable consequences? https://t.co/A6t4AxWmhy

May 16, 2020 · 56 followers View post →
ruminator
@jpsenosiain · X

@1CINyS estupendo alimento, pero ¡aguas si estás tomando medicinas! Grapefruit-medication interactions: forbidden fruit or avoidable consequences? Canadian Medical Association Journal 185: 309–16.

Feb 6, 2020 · 591 followers View post →
economicscience
@economicscience · X

RT @syuichiao89: こういう総説、地味に大事だよなあ。やはり横道なクリニカルクエスチョンに対する自分なりの答えはしっかり持っておきたい。 Grapefruit-medication interactions: forbidden fruit or avoidab…

Dec 21, 2019 · 3 shares · 5,733 followers View post →
くすりの家庭教師 ™奥村友紀【公式】
@tak_pom · X

RT @syuichiao89: こういう総説、地味に大事だよなあ。やはり横道なクリニカルクエスチョンに対する自分なりの答えはしっかり持っておきたい。 Grapefruit-medication interactions: forbidden fruit or avoidab…

Dec 21, 2019 · 3 shares · 12,885 followers View post →
いつくしみお
@rdmasud · X

RT @syuichiao89: こういう総説、地味に大事だよなあ。やはり横道なクリニカルクエスチョンに対する自分なりの答えはしっかり持っておきたい。 Grapefruit-medication interactions: forbidden fruit or avoidab…

Dec 20, 2019 · 3 shares · 683 followers View post →
青島周一
@syuichiao89 · X

こういう総説、地味に大事だよなあ。やはり横道なクリニカルクエスチョンに対する自分なりの答えはしっかり持っておきたい。 Grapefruit-medication interactions: forbidden fruit or avoidable consequences? - PubMed - NCBI https://t.co/vbbd7SALIH

Dec 20, 2019 · 15 likes · 3 shares · 8,605 followers View post →
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CMAJ 2012; DOI:10.1503/cmaj. 120951. Список лекарственных препаратов со временем обновляется и пополняется в связи с новыми исследованиями и ...

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CMAJ 2012; DOI:10.1503/cmaj. 120951. Список лекарственных препаратов со временем обновляется и пополняется в связи с новыми исследованиями и ...

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CMAJ. 2013 Mar 5;185(4):309-16. doi: 10.1503/cmaj.120951. Epub 2012 Nov 26. PMID: 23184849; PMCID: PMC3589309. 本文由當年發現葡萄柚與藥物 ...

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CMAJ. 2013 Mar 5;185(4):309-16. doi: 10.1503/cmaj.120951. Epub 2012 Nov 26. PMID: 23184849; PMCID: PMC3589309. 本文由當年發現葡萄柚與藥物 ...

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https://doi.org/10.1503/cmaj.120951 Hanley, M. J., Cancalon, P., Widmer, W. W., & Greenblatt, D. J. (2011/confirmado en revisiones 2018–2022) ...

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CMAJ 2012; DOI:10.1503/cmaj. 120951. Список лекарственных препаратов со временем обновляется и пополняется в связи с новыми исследованиями и ...

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CMAJ 2012; DOI: 10.1503/cmaj.120951. Список лекарственных препаратов со временем обновляется и пополняется в связи с новыми исследованиями и ...

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CMAJ 2012; DOI:10.1503/cmaj. 120951. Список лекарственных препаратов со временем обновляется и пополняется в связи с новыми исследованиями и ...

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CMAJ 2012; DOI:10.1503/cmaj. 120951. Список лекарственных препаратов со временем обновляется и пополняется в связи с новыми исследованиями и ...

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CMAJ 2012; DOI:10.1503/cmaj. 120951. Список лекарственных препаратов со временем обновляется и пополняется в связи с новыми исследованиями и ...

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... 10.1503/cmaj.120951 (2) Zhang, J., Liu, Y., Cheng, J., Li, W., Ma, H., Liu, H., . . . Yang, L. (2007). Inhibition of Human Liver Cytochrome ...

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... 10.1503/cmaj.120951 (2) Zhang, J., Liu, Y., Cheng, J., Li, W., Ma, H., Liu, H., . . . Yang, L. (2007). Inhibition of Human Liver Cytochrome ...

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... (CMAJ) un elenco di medicinali che se assunti in una dieta ... 4 First published November 26, 2012, doi: 10.1503/cmaj.120951 http ...

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... (CMAJ) un elenco di medicinali che se assunti in una dieta ... 4 First published November 26, 2012, doi: 10.1503/cmaj.120951 http ...

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... 10.1503/cmaj.120951 8) Dreier JP, Endres M. Statin-associated rhabdomyolysis triggered by grapefruit consumption. Neurology 2004;62:670. 9 ...

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CMAJ March 05, 2013 185 (4) 309-316; DOI: https://doi.org/10.1503/cmaj.120951. David G. Bailey. From the Lawson Health Research Institute ...

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Table of Contents — March 05, 2013, 185 (4) | CMAJ
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Arnold. CMAJ March 05, 2013 185 (4) 309-316; DOI: https://doi.org/10.1503/cmaj.120951. Practice. You have access. Decisions: Painful varicocele ...

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Canadian Medical Association Journal DOI: 10.1503/cmaj.120951. This article is not intended as medical advice, before making any changes to ...

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References. Bailey DG et al. CMAJ. 2012; doi:10.1503/cmaj.120951. Share this article.

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Journal reference: Canadian Medical Association Journal, DOI: 10.1503/cmaj.120951. Topics: medical drugs /; food and drink/; drugs.

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... CMAJ (Canadian Medical Association Journal). The article, a review ... Canadian Medical Association Journal, 2012; DOI: 10.1503/cmaj.120951 ...

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CMAJ 2012; DOI:10.1503/cmaj.120951. Copyright © 2012 Canadian Medical Association or its licensors. Appendix 1: Grapefruit Interacting Drugs ...

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This article has been peer reviewed. Correspondence to: David G. Bailey, david.bailey@lhsc.on.ca. CMAJ 2012. DOI:10.1503. /cmaj.120951. Review.

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CMAJ (Canadian Medical Association Journal). The article, a review by the ... More information: www.cmaj.ca/lookup/doi/10.1503/cmaj.120951.

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