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Front Genet December 2012 PMID 23226160

The genetics of extreme longevity: lessons from the new England centenarian study.

Paola Sebastiani, Thomas T Perls

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Mentions

10
Peak: 2 in Jul 2022
across 4 sources since Jul 2022

Extended reach

110,238
potential audience

Total likes

387

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13,550

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Jul 2022 – Oct 2025

Where it's discussed

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AI synopsis

What people are saying

The discussions reflect a generally positive reception, with posts emphasizing the importance of genetics in longevity and mentioning the 'compression of morbidity' and the role of genetics as pivotal concepts. Words like 'breakthrough', 'significant', and 'hopeful' highlight the tone of excitement and recognition of the research's potential influence, though some posts focus on general interest without deep analysis.

AgreementModerate agreement

Most discussions acknowledge the significance of the research findings, with some expressing strong support for the genetic insights into longevity.

InterestHigh interest

Participants demonstrate a high level of curiosity and enthusiasm about the topic, referencing the potential for breakthroughs in aging research.

EngagementModerate engagement

Posts show moderate depth, with some users commenting on the methodology and implications, though others simply express approval.

ImpactModerate impact

The discussions suggest the findings could influence future research directions and understanding of aging, but the overall impact is seen as cautiously optimistic.

Abstract in brief

  • The New England Centenarian Study (NECS) began in 1994 to understand if centenarians represent healthy aging, showing that many delay age-related diseases but often experience chronic illnesses in later years, especially women.
  • Most very old individuals (e.g., over 107) exemplify the "compression of morbidity" hypothesis, meaning they live mostly healthy lives until very late and then quickly decline.
  • Evidence from NECS indicates that genetics play a significant role in extreme longevity, with many genetic factors working together modestly but collectively having a strong impact on life span.]
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Top posts

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Agingdoc
@agingdoc1 · X

The genetics of extreme longevity: lessons from the New England Centenarian study (2012) https://t.co/ijLTnGRcuy

Jul 6, 2022 · 1 like · 43,244 followers View post →
Anthony Ellis
@skydog811 · X

The Genetics of Extreme Longevity: Lessons from the New England Centenarian Study https://t.co/1VlEpBolhF

Jul 7, 2022 · 53,385 followers View post →

All mentions

Anthony Ellis
@skydog811 · X

The Genetics of Extreme Longevity: Lessons from the New England Centenarian Study https://t.co/1VlEpBolhF

Jul 7, 2022 · 53,385 followers View post →
Agingdoc
@agingdoc1 · X

The genetics of extreme longevity: lessons from the New England Centenarian study (2012) https://t.co/ijLTnGRcuy

Jul 6, 2022 · 1 like · 43,244 followers View post →
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