Biochem J February 2013 PMID 23301657

Residue mutations and their impact on protein structure and function: detecting beneficial and pathogenic changes.

Romain A Studer, Benoit H Dessailly, Christine A Orengo

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Mentions

Peak: 7 in Dec 2021

across 4 sources since May 2019

Extended reach

9,408

potential audience

Total likes

105

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4,020

Mentions per month

May 2019 – Dec 2021

Where it's discussed

X / Twitter6 posts
YouTube3 videos
Blogs3 articles
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AI synopsis

What people are saying

The discussions demonstrate strong interest through queries about what mutations are and their relevance to variants like Omicron, with posts emphasizing the significance of understanding protein changes. The tone combines educational curiosity with recognition of the importance of mutation research in managing viral threats, reflecting thoughtful engagement and acknowledgment of the article's broader significance.

AgreementModerate agreement

Most discussions acknowledge the importance of understanding mutations, especially in the context of variants like Omicron.

InterestHigh interest

Posts show a high level of curiosity about mutations and their implications, especially relating to viral evolution.

EngagementModerate engagement

Participants reference specific concepts such as protein structure and mutations, indicating active thought and discussion.

ImpactModerate impact

The discussions highlight the relevance of the research for public health and understanding viral behavior, suggesting a moderate to high perceived impact.

Abstract in brief

This review discusses how amino acid mutations in proteins can influence their structure and function, highlighting how proteins evolve through periods of conservation and rapid change driven by natural selection.
It explains that the impact of mutations depends on various factors, such as the mutation's location within the protein's 3D structure and whether residues coevolve to maintain stability, with structural changes sometimes dramatically affecting protein function.
The review also emphasizes recent advances in tools and methods that combine protein biophysics, structure, and evolutionary studies to better understand how mutations, including beneficial and harmful ones, shape protein evolution, especially in contexts like viruses and animal genetics.]

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All mentions

Understanding Mutations and Their Impact on Protein Function

This video explains how amino acid mutations influence protein structure and function, highlighting their role in evolution and disease. It emphasizes recent advances in tools integrating biophysics, structure, and…

bioZone · Dec 13, 2021 3,174 views

Understanding Omicron Variants and Their Impact on Protein Function

This review discusses how amino acid mutations affect protein structure and function. It highlights the role of natural selection in protein evolution and recent advances in tools to analyze mutation impacts, especially…

bioZone · Dec 13, 2021 429 views

Understanding Omicron Mutations and Their Impact on Protein Function

This video explores how amino acid mutations affect protein structure and function, highlighting their role in viral evolution and disease. It discusses factors influencing mutation impact and recent advances in…

bioZone · Dec 13, 2021 417 views

TheSciCommCollective

@Sci_Comm_ · X

RT @thebiozone: lets talk omicron and mutations: first- what are mutations? (1/4) click below to support us by watching on YouTube

Dec 17, 2021 · 2 shares · 2,363 followers View post →

Academic YouTubers

@YTacademics · X

RT @thebiozone: lets talk omicron and mutations: first- what are mutations? (1/4) click below to support us by watching on YouTube

Dec 15, 2021 · 2 shares · 2,106 followers View post →

bioZone

@thebiozone · X

and finally- what does this mean for the new #Omicron variant? (3/4) https://t.co/qa1kf1cH4w https://t.co/NEAIpvFOR4

Dec 14, 2021 · 1 like · 186 followers View post →

bioZone

@thebiozone · X

what do mutations do? #Omicron (2/4) https://t.co/dwTKKbcIUI https://t.co/d11RxZfKu7

Dec 14, 2021 · 1 like · 186 followers View post →

Michael Carmody

@m_carmody · X

Residue Mutations and Their Impact on Protein Structure and Function: Detecting Beneficial and Pathogenic Changes - PubMed https://t.co/jc3ALz0iEE

Mar 30, 2020 · 185 followers View post →

K.I.

@genolib_19 · X

Residue mutations and their impact on protein structure and function: detecting beneficial and pathogenic changes https://t.co/vLJniYjQGp

May 4, 2019 · 354 followers View post →