Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weight gain of from 4 to 13 kg. No significant correlation between total calories and body weight or fat mass. https://t.co/zdEAUD1Kka
The response to long-term overfeeding in identical twins.
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Apr 2019 – Jun 2025Where it's discussed
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X / Twitter92 posts
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News27 articles
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Facebook11 posts
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Blogs10 articles
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Reddit3 posts
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YouTube2 videos
AI synopsis
What people are saying
Overall, the social discussions demonstrate a strong focus on genetic variability in body responses to overfeeding, with references to studies like Bouchard’s long-term twin experiment and commentary on metabolic differences. The tone ranges from scholarly references to dismissive remarks about misinformation, showing a mix of deep scientific interest and skepticism, which informs the moderate to high engagement and perceived impact.
Most discussions support the idea that genetics significantly influence responses to overfeeding, referencing classic studies like Bouchard et al. and emphasizing genetic contributions.
Posts show high interest by engaging with both historical and recent research, mentioning specific studies and referencing complex concepts like adipose distribution, indicating active curiosity.
While some comments dismiss superficial explanations, many participants analyze methods, cite scientific studies, and discuss genetic implications, reflecting moderate to deep engagement.
The discussions highlight that understanding individual differences affects how obesity and metabolism are approached, suggesting a meaningful influence on the broader scientific and health community.
Abstract in brief
- The study examined how identical twins respond differently to long-term overfeeding, with some gaining more weight and fat than others, indicating individual differences.
- Results showed that twins had highly similar responses within each pair regarding weight gain, fat percentage, and fat distribution, suggesting a genetic influence on these traits.
- The findings imply that genetics play a key role in how our bodies store energy and distribute fat, affecting weight gain and body composition during overfeeding.]
Top posts
Most liked on X and Bluesky"The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the impact of genetics on body fat gain, lean mass gain, and body fat distribution. https://t.co/zcrIw9sIUs
増量時の体重の増え方は遺伝子で決まる? https://t.co/1SA2k43aKQ 12組の一卵性双生児に、1日1000 kcalオーバーカロリーの食事を100日間させた結果、遺伝子が全く同じである双子兄弟の体重・脂肪増加量は似ていた。しかし、別の双子同士を比べると体重・脂肪増加量はバラバラだった。
@jen_logue @AbdTahrani Further supporting the “this is not about willpower theme” Some Cdn content
Deux études ont donné : - un apport fixe de +1000kcal - un régime hypocalorique de 1,6MJ/j https://t.co/zBG3n5xq7m https://t.co/CwX6gNMJQ2 On a constaté des réponses très variables en terme de poids pour un même apport de kcal !! https://t.co/avWQ5doX6x
References: Overfeeding Study: https://t.co/alMuZcQcNu Resting Metabolic Rate Study: https://t.co/AETSZBljUY NEAT Study: https://t.co/7NjS3njmkP Hunger Research: https://t.co/FuyxCqFg74 https://t.co/e9Qmlrswev
All mentions
Genetic Factors in Obesity and Individual Responses to Overfeeding
The response to long-term overfeeding in identical twins. Genetics significantly influence how individuals gain weight and store fat, with twins showing similar responses within pairs, indicating genetic predisposition…
The Genetic and Hormonal Factors Influencing Obesity and Weight Management
The obesity rate has doubled over the past 20 years. This video reviews scientific evidence on genetic, hormonal, and lifestyle factors involved in weight gain, including the roles of ghrelin, GLP-1, and PYY hormones in…
STUDY LINKS: Overfeeding Study: https://t.co/DlfzP0nykZ Resting Metabolic Rate Study: https://t.co/2EMJQmXqP5 NEAT Study: https://t.co/vOz77gcMzs Hunger Research: https://t.co/0hiQDNrjGk https://t.co/0Lqo5KXGCE
参考 https://t.co/ZcUY7sImFV
@adrusi bitches just be tweeting off the dome no research no peer reviewed articles just raw dogging misinformation https://t.co/FynpBPpdCX
RT @sudokeeen: 参考 https://t.co/ZcUY7sHOQn
参考 https://t.co/ZcUY7sHOQn
RT @jens_lund: Study 1: Bouchard et al. in @NEJM 33 years ago: https://t.co/0FGPf6b6xI
Study 1: Bouchard et al. in @NEJM 33 years ago: https://t.co/0FGPf6b6xI
@CurtTigges @seconds_0 going to put some over feeding experiments here, this normal carbohydrate one is interesting for the way there are not only wt diffs but also different patterns of adipose distribution for the gain depending on person, https://t.co/O1cYn9iYVy
RT @T_Fiolet: Deux études ont donné : - un apport fixe de +1000kcal - un régime hypocalorique de 1,6MJ/j https://t.co/zBG3n5xq7m https://t.…
RT @T_Fiolet: Deux études ont donné : - un apport fixe de +1000kcal - un régime hypocalorique de 1,6MJ/j https://t.co/zBG3n5xq7m https://t.…
Deux études ont donné : - un apport fixe de +1000kcal - un régime hypocalorique de 1,6MJ/j https://t.co/zBG3n5xq7m https://t.co/CwX6gNMJQ2 On a constaté des réponses très variables en terme de poids pour un même apport de kcal !! https://t.co/avWQ5doX6x
References: Overfeeding Study: https://t.co/alMuZcQcNu Resting Metabolic Rate Study: https://t.co/AETSZBljUY NEAT Study: https://t.co/7NjS3njmkP Hunger Research: https://t.co/FuyxCqFg74 https://t.co/e9Qmlrswev
@HermanPontzer Hello Dr. Pontzer. Thank you for your work on calories and metabolism. On the off chance you haven't seen it, here's some work showing how people handle calories differently: https://t.co/TTSMGoAqFm
@caloraNcs von wie schnell man verdaut, fett verbraucht, wie viele Kohlenhydrate man aufnimmt, wie stark das Hungergefühl ist, wie sehr der körper fett behält, es gibt sehr viele faktoren https://t.co/rVKwgmHatn https://t.co/3VZNOTUope https://t.co/2izsVRyhNM https://t.co/tq0ZRX5vIG
@MiriamBerchuk @MichelleCardel @sguyenet @MichaelAlbertMD https://t.co/WzACM7gCe0
@BanjoBouchon Absolutely the same amount of food = more weight gain for some. Likely the result of genetic differences in the oldest & lowest part of the human appetite system, the homeostatic system. https://t.co/lbCkA3VpXT
RT @DavidMacklinMD: @jen_logue @AbdTahrani Further supporting the “this is not about willpower theme” Some Cdn content
RT @DavidMacklinMD: @jen_logue @AbdTahrani Further supporting the “this is not about willpower theme” Some Cdn content
RT @DavidMacklinMD: @jen_logue @AbdTahrani Further supporting the “this is not about willpower theme” Some Cdn content
RT @DavidMacklinMD: @jen_logue @AbdTahrani Further supporting the “this is not about willpower theme” Some Cdn content
RT @DavidMacklinMD: @jen_logue @AbdTahrani Further supporting the “this is not about willpower theme” Some Cdn content
@jen_logue @AbdTahrani Further supporting the “this is not about willpower theme” Some Cdn content
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
RT @Mangan150: Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weigh…
Calories in / calories out doesn't account for weight gain. Overfeeding a total of 84,000 calories to 24 men led to a weight gain of from 4 to 13 kg. No significant correlation between total calories and body weight or fat mass. https://t.co/zdEAUD1Kka
@whsource @KevinH_PhD A favorite DFS from the Laval group circa 1990. Identical twins with elegant intrapair similarities in weight gain pointing to the significant contribution of genetics to the risk of weight gain. An absolute classic that has stood the test of 30 yrs! https://t.co/lbCkA3VpXT
@CharlesLucena3 @MikeAlbertMD https://t.co/60ldBJhpp9 This is the one that first comes to mind, not in a ward but this is not a pragmatic study. In a larger sample size, I'd expect outliers to be even further away from the mean but much more people within the first std deviation range.
RT @toharabrothers: 増量時の体重の増え方は遺伝子で決まる? https://t.co/1SA2k43aKQ 12組の一卵性双生児に、1日1000 kcalオーバーカロリーの食事を100日間させた結果、遺伝子が全く同じである双子兄弟の体重・脂肪増加量は似てい…
RT @toharabrothers: 増量時の体重の増え方は遺伝子で決まる? https://t.co/1SA2k43aKQ 12組の一卵性双生児に、1日1000 kcalオーバーカロリーの食事を100日間させた結果、遺伝子が全く同じである双子兄弟の体重・脂肪増加量は似てい…
RT @toharabrothers: 増量時の体重の増え方は遺伝子で決まる? https://t.co/1SA2k43aKQ 12組の一卵性双生児に、1日1000 kcalオーバーカロリーの食事を100日間させた結果、遺伝子が全く同じである双子兄弟の体重・脂肪増加量は似てい…
RT @toharabrothers: 増量時の体重の増え方は遺伝子で決まる? https://t.co/1SA2k43aKQ 12組の一卵性双生児に、1日1000 kcalオーバーカロリーの食事を100日間させた結果、遺伝子が全く同じである双子兄弟の体重・脂肪増加量は似てい…
RT @toharabrothers: 増量時の体重の増え方は遺伝子で決まる? https://t.co/1SA2k43aKQ 12組の一卵性双生児に、1日1000 kcalオーバーカロリーの食事を100日間させた結果、遺伝子が全く同じである双子兄弟の体重・脂肪増加量は似てい…
RT @toharabrothers: 増量時の体重の増え方は遺伝子で決まる? https://t.co/1SA2k43aKQ 12組の一卵性双生児に、1日1000 kcalオーバーカロリーの食事を100日間させた結果、遺伝子が全く同じである双子兄弟の体重・脂肪増加量は似てい…
増量時の体重の増え方は遺伝子で決まる? https://t.co/1SA2k43aKQ 12組の一卵性双生児に、1日1000 kcalオーバーカロリーの食事を100日間させた結果、遺伝子が全く同じである双子兄弟の体重・脂肪増加量は似ていた。しかし、別の双子同士を比べると体重・脂肪増加量はバラバラだった。
3/ Fat-gain null hypothesis: overfeeding will⬆️total (or relative) fat mass proportionally This null hypothesis also fails. See this experiment https://t.co/W9NoC8YswB "The response to long-term overfeeding in identical twins"
Jak to jest, że nawet bliźniaki chociaż jedliby tyle samo dalej mogą różnić się masą i kompozycją ciała? Odpowiedz jest prosta i każdy ją pewnie zna, geny. Badanie jest już dość stare ale jeśli kogoś interesuje część genetyczna to polecam: #fitkwiecień https://t.co/oGKzueESIa
RT @alshatti_fit: "الاستجابة للتغذية الطويلة الأجل في التوائم" دراسة أجراها Bouchard توضح تأثير الوراثة على زيادة الدهون في الجسم ، وزيا…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
"الاستجابة للتغذية الطويلة الأجل في التوائم" دراسة أجراها Bouchard توضح تأثير الوراثة على زيادة الدهون في الجسم ، وزيادة كتلة الدهون ، وتوزيع الدهون في الجسم. تميل التوائم إلى الحصول على كمية مماثلة من الدهون ، في نفس الأماكن. https://t.co/Xb7I7gfJo8
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
RT @whsource: "The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the im…
"The Response to Long-Term Overfeeding in Identical Twins". Classic study by Bouchard and colleagues that illustrates the impact of genetics on body fat gain, lean mass gain, and body fat distribution. https://t.co/zcrIw9sIUs
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