The supplementation of L-carnitine may also raise blood levels of trimethylamine-N-oxide (TMAO) over time. High levels of TMAO are linked to an increased risk of atherosclerosis. https://t.co/YRa8OQO2hr
Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk.
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Jun 2016 – Jun 2025Where it's discussed
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News59 articles
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Facebook42 posts
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AI synopsis
What people are saying
The discussions demonstrate a critical engagement with the research, with posts highlighting the health risks of foods rich in choline and TMAO, such as eggs and meats. Words like 'harmful,' 'risk,' and references to expert opinions emphasize concern and the perceived significance of this study on public health and dietary habits.
Most discussions acknowledge TMAO's connection to cardiovascular risk, with some posts citing specific studies and experts, suggesting general support or recognition of the research's importance.
The posts reveal high curiosity about dietary sources and implications, evident in references to eggs, choline, and meat, as well as mentions of potential health risks, indicating strong engagement with the topic.
While some posts briefly mention foods or cite studies, others delve into interpretations of research findings or call for attention to public health messaging, showing moderate depth of involvement.
The tone suggests that many users see this research as potentially influential, with references to changing dietary advice and skepticism of industry influence, although not everyone explicitly claims it to be a game changer.
Abstract in brief
- Recent research shows that the gut bacteria process dietary phosphatidylcholine (found in foods like eggs) into a compound called TMAO, which is linked to an increased risk of heart disease.
- In humans, higher plasma TMAO levels, especially after eating phosphatidylcholine, are associated with a greater chance of major cardiovascular events like heart attacks or strokes over a 3-year period.
- The study found that antibiotics reducing gut bacteria lowered TMAO levels, indicating that TMAO production depends on intestinal microbes, and that elevated TMAO could be a useful marker for cardiovascular risk.]
Top posts
Most liked on X and Bluesky研究あんじゃん “ホスファチジルコリンの腸内微生物代謝と心血管リスク” 「食事中のホスファチジルコリンからのTMAOの生成は、腸内細菌叢による代謝に依存しています。TMAOレベルの上昇は、主要な心血管系有害事象の発生リスクの上昇と関連しています。」 だ、そうぞ https://t.co/YmRNUKCcJi https://t.co/71vfguMC1w
TMAO’s toxic effects..#kidneywk ..more elevated in CKD pts https://t.co/6YaAoE5AxQ
@Mangan150 Dr. Hazen's group showed that increased levels of TMAO in the blood are associated with cardiovascular disease (CVD). https://t.co/oL310JSLmx
@HallionWild @VeganRecovering https://t.co/fDCXzDgYPZ
Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk | NEJM https://t.co/ZMkPQnIv01 https://t.co/WEnmHwIbwb
All mentions
New Insights on Meat and Heart Disease Risk
Recent research indicates that gut bacteria process dietary phosphatidylcholine, found in foods like eggs and meat, into TMAO, which is linked to increased heart disease risk. Higher TMAO levels may serve as a marker…
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Our gut controls inflammation which drives heart disease and helps regulate cholesterol and blood sugar. This video explores how gut bacteria influence medication effectiveness, inflammation, and blood markers…
Accelerating the Vegan Revolution for Better Public Health and Environment
This video explains why a balanced vegan diet improves COVID-19 outcomes. The vegan revolution is seen as vital for health, animal rights, and environmental sustainability. Governments should expedite this transition…
Gut Microbial Metabolism of Phosphatidylcholine and Heart Disease Risk
Recent research shows that gut bacteria process dietary phosphatidylcholine into TMAO, linked to increased heart disease risk. Elevated plasma TMAO indicates higher chances of cardiovascular events, and reducing gut…
Egg Consumption and Cardiovascular Risk: Insights from Recent Research.
Recent research reveals that gut bacteria process dietary phosphatidylcholine in eggs into TMAO, which is linked to increased cardiovascular risk. Elevated TMAO levels are associated with higher chances of heart attacks…
RT @komomo_Com: コリンがTMAOに変換しやすい人はコリンを摂取したら動脈硬化のリスクが上がるのだろうな。 https://t.co/gxhGsjO5Il
RT @komomo_Com: コリンがTMAOに変換しやすい人はコリンを摂取したら動脈硬化のリスクが上がるのだろうな。 https://t.co/gxhGsjO5Il
コリンがTMAOに変換しやすい人はコリンを摂取したら動脈硬化のリスクが上がるのだろうな。 https://t.co/gxhGsjO5Il
@hyderabaddoctor Eggs are highly harmful to health. A study looking at egg consumption found that TMAO, a byproduct of dietary choline, can lead to a greater risk of heart attack, stroke, and death.https://t.co/LSPafBbyqz
@xxsancto @TwitchAsleyia "this one issue involving TMAO is, according to the recent president of the American College of Cardiology Dr. Kim A. Williams, sufficient by itself for people to vigorously avoid animal foods." Forks over Knives bezieht sich auf die Studie https://t.co/KaYCCyFy0b
https://t.co/zpa9HJ2Sjj
The supplementation of L-carnitine may also raise blood levels of trimethylamine-N-oxide (TMAO) over time. High levels of TMAO are linked to an increased risk of atherosclerosis. https://t.co/YRa8OQO2hr
@goddeketal By the way. Choline not so good for humans. We are herbivores/starchivores. MSM will start telling the truth about CVD to pivot. Big food not gonna like this! https://t.co/1HZ33Ebx3x
@richardosman The sign should also include this photo of a hen reproductive system (which is what you are eating) & links to credible studies like this one from NEJM showing the risks of eating sat fat & cholesterol-laden hen periods. #vegan https://t.co/mRXWngCKF8 https://t.co/eTWnVyTI4q
@PierretteDe2 @SBakerMD Humans produce all the choline they need. Excess/external choline produces higher plasma TMAO levels, "which predicted an increased risk of major adverse cardiovascular events after adjustment for traditional risk factors." https://t.co/mRXWngCKF8 https://t.co/UVM50zoZHM
@kevinnbass @TyRBeal @maxlugavere @fleroy1974 @drdairy50 @TheAlanAragon What about the increased risks for major adverse cardiovascular events (& likely certain cancers & T2D as well) with increased exogenous choline & subsequent greater TMAO levels? 500mg is equivalent to 4 eggs/day.
@Mangan150 Dr. Hazen's group showed that increased levels of TMAO in the blood are associated with cardiovascular disease (CVD). https://t.co/oL310JSLmx
@q21407434 @djwilso @StickmanBleedin An elevated TMAO level predicted an increased risk of major adverse cardiovascular events after adjustment for traditional risk factors (P<0.001), as well as in lower-risk subgroups. https://t.co/Jofttrylzk
研究あんじゃん “ホスファチジルコリンの腸内微生物代謝と心血管リスク” 「食事中のホスファチジルコリンからのTMAOの生成は、腸内細菌叢による代謝に依存しています。TMAOレベルの上昇は、主要な心血管系有害事象の発生リスクの上昇と関連しています。」 だ、そうぞ https://t.co/YmRNUKCcJi https://t.co/71vfguMC1w
@HallionWild @VeganRecovering https://t.co/fDCXzDgYPZ
Kaynaklar https://t.co/jGhZbyIF9C https://t.co/7BMMYHSs8c https://t.co/Z9yZW2jYIP https://t.co/bnBvKKoeA7 https://t.co/TYyYQZ5ogN
RT @GenNextMD: TMAO’s toxic effects..#kidneywk ..more elevated in CKD pts https://t.co/6YaAoE5AxQ
RT @GenNextMD: TMAO’s toxic effects..#kidneywk ..more elevated in CKD pts https://t.co/6YaAoE5AxQ
TMAO’s toxic effects..#kidneywk ..more elevated in CKD pts https://t.co/6YaAoE5AxQ
Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk | NEJM https://t.co/MhQbaOYtVT
@kdinbburg @EAllen0417 @whsource See table S1 in suppl appendix. Not a healthy population. As TMAO rises, other biomarkers get worse also. Who knows if TMAO is an independent variable? https://t.co/w7ZISK9gDN
@kdinbburg @EAllen0417 @whsource And here Table 1. Note all the studies listed are of patients with disease. Tang 2013 is listed as a study of the general population but it's of angiography pts (not a healthy pop). Ex. avg HDL in this group is approx 34. https://t.co/BtUkHdcMRr https://t.co/w7ZISK9gDN
Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk | NEJM https://t.co/ZMkPQnIv01 https://t.co/WEnmHwIbwb
Une nouvelle étude sur la viande ! https://t.co/9gsNcOx35A via @YouTube
Une nouvelle étude sur la viande ! https://t.co/8rq9IOCrad via @YouTube
@Observerzzzzzz @MassiMassian @ChrisMasterjohn I assume you are familiar with Hazen's work here. https://t.co/RsD9Pwi09q Also here: https://t.co/GuS4Nw35ki It's important to note that TMAO was discovered by untargeted metabolomic analysis, so VERY unlikely to be a spurious association. https://t.co/WLiVSgDt56