Diabetes Care September 2013 PMID 23633524

Sucralose affects glycemic and hormonal responses to an oral glucose load.

M Yanina Pepino, Courtney D Tiemann, Bruce W Patterson, Burton M Wice, Samuel Klein

Mentions

250
Peak: 7 in Jul 2020
across 5 sources since Apr 2020

Extended reach

243,441
potential audience

Total likes

76

Video views

914

Mentions per month

Apr 2020 – Sep 2025

Where it's discussed

  • Facebook118 posts
  • News74 articles
  • X / Twitter40 posts
  • Blogs15 articles
  • YouTube3 videos

AI synopsis

What people are saying

Several discussions highlight the significance of the findings, such as mentions of how sucralose influences glucose and insulin responses, with phrases like 'Pay attention!' and references to scientific articles underlining the seriousness. The tone ranges from curiosity to cautious skepticism, with some users emphasizing the potential health implications and others questioning the conclusiveness of the research, all contributing to a nuanced view of the article's impact.

AgreementNeither agree nor disagree

The discussions show mixed opinions, with some posts acknowledging the study's findings but not strongly supporting or rejecting its conclusions.

InterestHigh interest

There is high interest evidenced by the frequent mentions of the article, calls to pay attention, and sharing of related scientific studies and comments.

EngagementModerate engagement

A number of discussions delve into details, referencing specific studies, methodologies, and potential health effects, indicating an active and somewhat deep engagement.

ImpactModerate impact

While some posts highlight the significance of the research, many express caution or skepticism, suggesting they see potential importance but not a consensus on its impact.

Abstract in brief

  • Sucralose consumption before a glucose load increases blood sugar levels and insulin responses in obese individuals, indicating it may impact how their bodies handle glucose.
  • The study found that sucralose leads to higher peak glucose and insulin secretion, reduces insulin clearance, and decreases insulin sensitivity, suggesting it could impair metabolic regulation.
  • However, sucralose did not significantly change other hormones like glucagon-like peptide 1 or glucagon, highlighting its specific effects on glucose and insulin dynamics in humans.

Top posts

Most liked on X and Bluesky
tune
@keisuke4713 · X

スクラロース 血糖・ホルモン影響https://t.co/OrkN8OnJuS インスリン感受性肥満17人BMI42.3±1.6 別機会に5h修正経口ブドウ糖負荷試験 ブドウ糖負荷10分前スクラロースか水消費 スクラロース摂取 peak糖⬆️4.2±0.2対4.8±0.3 インスリン(I)20±8%⬆️ Ipeak分泌率22±7%⬆️ Iクリアランス7±4%⬇️とI刺激

Mar 8, 2022 · 9 likes · 3 shares · 3,736 followers View post →
Charlotte°❀⋆
@charlottexou · X

> Metabolic Health Meaning, artificial sweeteners may contribute to weight gain and metabolic syndrome, a cluster of conditions that increase the risk of heart disease, stroke, and diabetes https://t.co/ujef1YGwwh https://t.co/ChYywmdBRl

Jul 18, 2024 · 7 likes · 11,335 followers View post →
Charlotte°❀⋆
@charlottexou · X

https://t.co/VKmFKqEFhv https://t.co/TFOK6sKpdN https://t.co/ZhfYJggc8o https://t.co/iX4OYP0UfH https://t.co/6VoI7OuRio https://t.co/b0Md91V1zO https://t.co/sCiB1rzToy https://t.co/hNXKXeGfyb https://t.co/fU1cuhcYyS https://t.co/wc3dEISFX8

Dec 17, 2024 · 6 likes · 11,335 followers View post →
Altered State
@DeathXmd · X

@kujoonacti @kirawontmiss https://t.co/HoxMnShfzR https://t.co/YrXdoy8ZLK https://t.co/0qdGpeDg5V https://t.co/jTpQ5eCYNO https://t.co/oI2iCgNbG7

Apr 23, 2023 · 6 likes · 458 followers View post →
Robb Cabansag
@RobbCab · X

@PlanetOTheVapes I wouldn't go that far. The latest study was conducted on obese (BMI 43+) insulin-sensitive subjects and they ingested 75g of glucose & were then exposed to 48mg of sucralose (about a 12oz can of diet soda) to spike 20%. Vapes are probably ok. https://t.co/Ebm27JnZTH

Dec 8, 2023 · 3 likes · 2 shares · 527 followers View post →
睡眠良くしたければケトジェニック!(低糖質&高脂質)|小林充典|睡眠歯科医療3000人・減量指導
@tolucky39 · X

参考文献 Sucralose Affects Glycemic and Hormonal Responses to an Oral Glucose Load(全文) https://t.co/ahFDGrXAB3   プロテインにもスクラロース入っているもの多いです しかもタンパク質もブドウ糖に50%変換されますから、プロテインの取り過ぎも要注意です! https://t.co/vpre1AfbEB

May 3, 2020 · 2 likes · 1,082 followers View post →

All mentions

The Impact of Artificial Sweeteners on Health

Artificial sweeteners like aspartame and saccharin are commonly used as sugar alternatives, but they may promote cravings, obesity, and type 2 diabetes. This video examines scientific evidence regarding their health…

Shelium · Jun 25, 2022 348 views
Charlotte°❀⋆
@charlottexou · X

https://t.co/VKmFKqEFhv https://t.co/TFOK6sKpdN https://t.co/ZhfYJggc8o https://t.co/iX4OYP0UfH https://t.co/6VoI7OuRio https://t.co/b0Md91V1zO https://t.co/sCiB1rzToy https://t.co/hNXKXeGfyb https://t.co/fU1cuhcYyS https://t.co/wc3dEISFX8

Dec 17, 2024 · 6 likes · 11,335 followers View post →
dauntlesslogic
@dauntlesslogic · X

@deirdre_tobias @LuckyDaniLV https://t.co/bKowZXFTKi https://t.co/QrQCwZL1qW https://t.co/fYHZj2cPl2 https://t.co/U5fQISn45Q https://t.co/Jg6b9yyPq0

Dec 1, 2024 · 2 likes · 848 followers View post →
Charlotte°❀⋆
@charlottexou · X

@elysiasbones Artificial sweeteners study’s https://t.co/VKmFKqE7rX https://t.co/At5AJROc2u https://t.co/ujef1YFYGJ https://t.co/DZY3kKFcon https://t.co/492yPZdwNf https://t.co/iX4OYP0mq9 https://t.co/yj303YoVA9

Oct 28, 2024 · 1 like · 11,335 followers View post →
Charlotte°❀⋆
@charlottexou · X

> Metabolic Health Meaning, artificial sweeteners may contribute to weight gain and metabolic syndrome, a cluster of conditions that increase the risk of heart disease, stroke, and diabetes https://t.co/ujef1YGwwh https://t.co/ChYywmdBRl

Jul 18, 2024 · 7 likes · 11,335 followers View post →
Fred
@The_real_FredF · X

@digibruce @iLoveJaneAdams @JG_CSTT "Aspartame ingestion and glucose metabolism in non-insulin-dependent diabetes mellitus," Diabetes Care. "Sucralose affects glycemic and hormonal responses to an oral glucose load," Diabetes Care. "Metabolic effects of acesulfame potassium in humans," various sources.

Jun 11, 2024 · 2 likes · 731 followers View post →
JacobFinite
@JacobFinite · X

@carlsgeist @AdvantageM39786 @Everybody5Dad @fl_Joe_ @robertlufkinmd How do you explain these results then? https://t.co/AqmBj87xFG

May 28, 2024 · 217 followers View post →
EvilJanusz
@EvilJanusz · X

Sucralose affects glycemic and hormonal responses to an oral glucose load https://t.co/CjIbhz4C3p

May 16, 2024 · 251 followers View post →
stop blowing smoke
@harmreduced · X

RT @RobbCab: @PlanetOTheVapes I wouldn't go that far. The latest study was conducted on obese (BMI 43+) insulin-sensitive subjects and they…

Dec 8, 2023 · 2 shares · 487 followers View post →
Robb Cabansag
@RobbCab · X

@PlanetOTheVapes I wouldn't go that far. The latest study was conducted on obese (BMI 43+) insulin-sensitive subjects and they ingested 75g of glucose & were then exposed to 48mg of sucralose (about a 12oz can of diet soda) to spike 20%. Vapes are probably ok. https://t.co/Ebm27JnZTH

Dec 8, 2023 · 3 likes · 2 shares · 527 followers View post →
at sushi
@JOf1MMMIos9r0y0 · X

RT @keisuke4713: スクラロース 血糖・ホルモン影響https://t.co/OrkN8OnJuS インスリン感受性肥満17人BMI42.3±1.6 別機会に5h修正経口ブドウ糖負荷試験 ブドウ糖負荷10分前スクラロースか水消費 スクラロース摂取 peak糖…

Jul 1, 2023 · 3 shares · 4,059 followers View post →
Altered State
@DeathXmd · X

@kujoonacti @kirawontmiss https://t.co/HoxMnShfzR https://t.co/YrXdoy8ZLK https://t.co/0qdGpeDg5V https://t.co/jTpQ5eCYNO https://t.co/oI2iCgNbG7

Apr 23, 2023 · 6 likes · 458 followers View post →
Javi Ciborro
@papayaykware · X

https://t.co/YgqSRwtUU6

Apr 22, 2023 · 8,040 followers View post →
Carlos Esguerra
@CarlosEsguerra4 · X

@Ludde94813454 @endocrinorosero Luego de eso. Hay algunos estudios que muestran activaciones de insulina, incluso en edulcorantes sin calorias. Eso no es necesariamente malo, pero debe tenerse en cuenta. https://t.co/YhcELr4GkB

Apr 14, 2023 · 206 followers View post →
Princess Rootin Tuber Tater Salid
@hrhpotatosalid · X

Sucralose Affects Glycemic and Hormonal Responses to an Oral Glucose Load https://t.co/APGwTTTBT3

Mar 10, 2023 · 691 followers View post →
Javi Ciborro
@papayaykware · X

https://t.co/YgqSRwtUU6

Mar 7, 2023 · 8,040 followers View post →
Arya Su
@hira__lena · X

Splenda (Sukraloz) Diyabeti Teşvik Eden Etkileri Bulundu https://t.co/ug4seTOODQ

Sep 18, 2022 · 3,136 followers View post →
William Donelson
@donelson52 · X

@curd0g https://t.co/JhSwoz3Ndi

Sep 9, 2022 · 10,352 followers View post →
William Donelson
@donelson52 · X

WOW. Pay attention! Please! https://t.co/JhSwoz3Ndi

Aug 23, 2022 · 10,352 followers View post →
Aléksandèr K. ⚡
@macroarray · X

Incredibili le schifezze che mettono negli integratori. Si salva sì e no qualche marca. Dagli edulcoranti fino a zuccheri, fibre varie. Praticamente rimane Pure Encapsulation, Kirkman e uno che sto vedendo ora Fair & Pure. Per dire ovunque il sucralosio https://t.co/2n7s0jggPS

Aug 6, 2022 · 2 likes · 822 followers View post →
AConcernedParent
@AConcernedPare2 · X

@MarcusBeam1 @lelia_glass @subsix848 https://t.co/dGS9z2Fb1V (About splenda, not aspartame, but similar mechanism). I've also read studies that imply the insulin piece is dependent on genetics (some people are affected, some aren't).

Jun 20, 2022 · 1 like · 12,347 followers View post →
tune
@keisuke4713 · X

スクラロース 血糖・ホルモン影響https://t.co/OrkN8OnJuS インスリン感受性肥満17人BMI42.3±1.6 別機会に5h修正経口ブドウ糖負荷試験 ブドウ糖負荷10分前スクラロースか水消費 スクラロース摂取 peak糖⬆️4.2±0.2対4.8±0.3 インスリン(I)20±8%⬆️ Ipeak分泌率22±7%⬆️ Iクリアランス7±4%⬇️とI刺激

Mar 8, 2022 · 9 likes · 3 shares · 3,736 followers View post →
Ömer Faruk Divarcı
@omerfarukdvrc · X

@kardiyobey Okumak isteyenler için hocanın başlığını paylaştığı çalışma

Mar 6, 2022 · 147 followers View post →
Alaín Roberto
@AlainRNazario · X

RT @AlanaLolita: @AlainRNazario Le comparto el super interesante artículo científico. https://t.co/mz6qI3vuDL

Sep 18, 2021 · 1 share · 1,245 followers View post →
Dra. Alana Marrero González
@AlanaLolita · X

@AlainRNazario Le comparto el super interesante artículo científico. https://t.co/mz6qI3vuDL

Sep 18, 2021 · 1 like · 1 share · 3,149 followers View post →
Patrick Hsieh
@PatrickHsie · X

@notmyChris 1 蔗糖素 Pepino, M Yanina et al. “Sucralose affects glycemic and hormonal responses to an oral glucose load.” Diabetes care vol. 36,9 (2013): 2530-5. doi:10.2337/dc12-2221

Jul 29, 2021 · 1 like · 358 followers View post →
Peter Voshol
@Peter_Voshol · X

RT @drmowll: @KetoCarnivore @drmarkhyman @Peter_Voshol This is far from conclusive but provides some evidence: https://t.co/m3zHgG6KHv

Jun 24, 2021 · 1 share · 1,918 followers View post →
Dr. Brian Mowll
@drmowll · X

@KetoCarnivore @drmarkhyman @Peter_Voshol This is far from conclusive but provides some evidence: https://t.co/m3zHgG6KHv

Jun 24, 2021 · 1 like · 1 share · 1,288 followers View post →
Dr. Brian Mowll
@drmowll · X

@Rydo111 @drmarkhyman Far from conclusive but here is some: https://t.co/m3zHgG6KHv

Jun 24, 2021 · 1 like · 1,288 followers View post →
thalesnemo
@thalesnemo · X

@ferventfinance @SteveOnSpeed Artificial sweeteners have been shown to spike blood glucose as the body’s anticipatory response. https://t.co/TXKEjPyxo9

Jun 4, 2021 · 1,112 followers View post →
seri
@Smile_Seri · X

RT @ShigekiKanamori: 【断糖高脂質食と糖質制限は根本が違う】 人工甘味料スクラロースはBSに影響を与えなくてもinsulinは22%上昇 ケトン体が出るのを邪魔する (図表) https://t.co/aeU85af1OL 低糖質sweetsダメ

Jul 21, 2020 · 60 shares · 1,020 followers View post →
とこまるこ
@live_mitokotoko · X

RT @ShigekiKanamori: 【断糖高脂質食と糖質制限は根本が違う】 人工甘味料スクラロースはBSに影響を与えなくてもinsulinは22%上昇 ケトン体が出るのを邪魔する (図表) https://t.co/aeU85af1OL 低糖質sweetsダメ

Jul 21, 2020 · 60 shares · 910 followers View post →
金森重樹@ダイエットonlineサロン
@ShigekiKanamori · X

RT @ShigekiKanamori: 【断糖高脂質食と糖質制限は根本が違う】 人工甘味料スクラロースはBSに影響を与えなくてもinsulinは22%上昇 ケトン体が出るのを邪魔する (図表) https://t.co/aeU85af1OL 低糖質sweetsダメ

Jul 21, 2020 · 60 shares · 125,503 followers View post →
何にでも醤油をかけるひろちょす
@hirocos2 · X

RT @ShigekiKanamori: 【断糖高脂質食と糖質制限は根本が違う】 人工甘味料スクラロースはBSに影響を与えなくてもinsulinは22%上昇 ケトン体が出るのを邪魔する (図表) https://t.co/aeU85af1OL 低糖質sweetsダメ

Jul 12, 2020 · 60 shares · 1,793 followers View post →
タイタイ
@y1_h9 · X

RT @ShigekiKanamori: 【断糖高脂質食と糖質制限は根本が違う】 人工甘味料スクラロースはBSに影響を与えなくてもinsulinは22%上昇 ケトン体が出るのを邪魔する (図表) https://t.co/aeU85af1OL 低糖質sweetsダメ

Jul 12, 2020 · 60 shares · 84 followers View post →
あまね
@63QHxFAzN2WW9xA · X

RT @ShigekiKanamori: 【断糖高脂質食と糖質制限は根本が違う】 人工甘味料スクラロースはBSに影響を与えなくてもinsulinは22%上昇 ケトン体が出るのを邪魔する (図表) https://t.co/aeU85af1OL 低糖質sweetsダメ

Jul 12, 2020 · 60 shares · 28 followers View post →
ぽてぽて
@potepote029 · X

RT @ShigekiKanamori: 【断糖高脂質食と糖質制限は根本が違う】 人工甘味料スクラロースはBSに影響を与えなくてもinsulinは22%上昇 ケトン体が出るのを邪魔する (図表) https://t.co/aeU85af1OL 低糖質sweetsダメ

Jul 12, 2020 · 60 shares · 18 followers View post →
xacam(しゃかむ)
@xacam2 · X

RT @ShigekiKanamori: 【断糖高脂質食と糖質制限は根本が違う】 人工甘味料スクラロースはBSに影響を与えなくてもinsulinは22%上昇 ケトン体が出るのを邪魔する (図表) https://t.co/aeU85af1OL 低糖質sweetsダメ

Jun 5, 2020 · 60 shares · 27 followers View post →
睡眠良くしたければケトジェニック!(低糖質&高脂質)|小林充典|睡眠歯科医療3000人・減量指導
@tolucky39 · X

参考文献 Sucralose Affects Glycemic and Hormonal Responses to an Oral Glucose Load(全文) https://t.co/ahFDGrXAB3   プロテインにもスクラロース入っているもの多いです しかもタンパク質もブドウ糖に50%変換されますから、プロテインの取り過ぎも要注意です! https://t.co/vpre1AfbEB

May 3, 2020 · 2 likes · 1,082 followers View post →
森谷 良行
@moriyashika · X

RT @tolucky39: 糖質制限ってただ糖質量を減らせばいいってもんでもないってお話   スクラロースは経口ブドウ糖負荷に対する血糖およびホルモン反応に影響を与える Sucralose affects glycemic and hormonal responses to…

Apr 30, 2020 · 1 share · 179 followers View post →
睡眠良くしたければケトジェニック!(低糖質&高脂質)|小林充典|睡眠歯科医療3000人・減量指導
@tolucky39 · X

糖質制限ってただ糖質量を減らせばいいってもんでもないってお話   スクラロースは経口ブドウ糖負荷に対する血糖およびホルモン反応に影響を与える Sucralose affects glycemic and hormonal responses to an oral glucose load. 参考文献 https://t.co/CSk0AKi8QK

Apr 30, 2020 · 1 like · 1 share · 1,082 followers View post →