PubHawk
Hepatology April 2014 PMID 23929677

Caffeine stimulates hepatic lipid metabolism by the autophagy-lysosomal pathway in mice.

Rohit A Sinha, Benjamin L Farah, Brijesh K Singh, Monowarul M Siddique, Ying Li, Yajun Wu, Olga R Ilkayeva, Jessica Gooding, Jianhong Ching, Jin Zhou, Laura Martinez, Sherwin Xie, Boon-Huat Bay, Scott A Summers, Christopher B Newgard

Download social card

Mentions

84
Peak: 35 in Aug 2022
across 5 sources since Dec 2019

Extended reach

798,889
potential audience

Total likes

4,984

Video views

135,012

Mentions per month

Dec 2019 – Mar 2025

Where it's discussed

  • X / Twitter49 posts
  • News16 articles
  • Facebook10 posts
  • YouTube5 videos
  • Blogs4 articles

AI synopsis

What people are saying

The overall tone reflects positive interest, with many emphasizing how caffeine stimulates hepatic autophagy and reduces fat, such as mentions of 'caffeine surprisingly is a potent stimulator' and references to its therapeutic potential, demonstrating both curiosity and support for the publication's implications.

AgreementModerate agreement

Most discussions support the findings, emphasizing caffeine's role in reducing liver fat and stimulating autophagy.

InterestModerate interest

The posts express moderate curiosity, with some referencing potential health benefits and mechanisms discussed in the publication.

EngagementModerate engagement

Participants actively share related content, such as videos and examples, indicating a reasonable depth of engagement.

ImpactModerate impact

The discussions suggest a shared belief that these findings could influence dietary or medical approaches to liver health.

Top posts

Most liked on X and Bluesky
Dr. Mobeen Syed
@drbeen_medical · X

Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 4, 2022 · 67 likes · 24 shares · 33,070 followers View post →
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

Indeed, "caffeine surprisingly is a potent stimulator of hepatic autophagic flux" Caffeine reduces liver fat and stimulates β‐oxidation (fat burning) in hepatic cells and liver by an autophagy pathway Which means it treats fatty liver https://t.co/CTx3cgw8Zm

Feb 26, 2021 · 49 likes · 6 shares · 294,161 followers View post →
every_other_evelyn
@EvelynOther · X

@C_Gardner55 @EthicalSkeptic Fasting to induce autophagy has many proponents when it comes to cancer. Dr. Been recently covered the role of caffeine in assisting the process. https://t.co/fdk1JFReCZ

Aug 18, 2022 · 14 likes · 1,077 followers View post →
Analyze & Optimize
@Outdoctrination · X

The gut and the liver are also connected, since the liver must detoxify things that may slip through the cracks. Once again, coffee to the rescue! Caffeine has been shown to significantly reduce liver fat accumulation in animal models: https://t.co/ZCJy2f6B5a

May 31, 2021 · 5 likes · 1 share · 118,498 followers View post →
ARUN KUMAR
@arunkumar3112 · X

Caffeine stimulates hepatic lipid metabolism by the autophagy. https://t.co/qujTfx2gsM

Mar 14, 2023 · 5 likes · 14,839 followers View post →
Robert Keller
@findcommground · X

Caffeine and Autophagy To Reduce Fats in Liver https://t.co/SMkd5chJIy via @YouTube

Aug 17, 2022 · 2 likes · 1,201 followers View post →

All mentions

Caffeine's Impact on Liver Fat Reduction

Caffeine can stimulate hepatic lipid metabolism, potentially lowering liver fat levels. This video explores findings that highlight how caffeine affects liver health and fat metabolism, based on recent scientific…

Eli Shiff · Oct 1, 2022 47 views
Denise
@DeniseK1805 · X

https://t.co/HmGctCl8kl

Mar 10, 2025 · 531 followers View post →
Enrique Manzulli
@e_manfitnesss · X

RT @Mangan150: Indeed, "caffeine surprisingly is a potent stimulator of hepatic autophagic flux" Caffeine reduces liver fat and stimulates…

Jan 4, 2025 · 6 shares · 41 followers View post →
MussoliniOfBoobs
@MussoliniOfBoob · X

RT @Mangan150: Indeed, "caffeine surprisingly is a potent stimulator of hepatic autophagic flux" Caffeine reduces liver fat and stimulates…

Jan 3, 2025 · 6 shares · 444 followers View post →
z Boží vůle frajer
@JiriBogdan · X

@AlpacaAurelius ✅ https://t.co/dvJbyh3cEg

Jul 31, 2023 · 1,618 followers View post →
ARUN KUMAR
@arunkumar3112 · X

Caffeine stimulates hepatic lipid metabolism by the autophagy. https://t.co/qujTfx2gsM

Mar 14, 2023 · 5 likes · 14,839 followers View post →
Jackie
@PuttytatandMax · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Feb 4, 2023 · 24 shares · 314 followers View post →
Mark Estabrook
@EuromaidanRev · X

RT @EuromaidanRev: https://t.co/oZzX0KtN9R #Leronlimab #NAFLD #Autophagy

Sep 5, 2022 · 1 share · 108 followers View post →
Mark Estabrook
@EuromaidanRev · X

https://t.co/oZzX0KtN9R #Leronlimab #NAFLD #Autophagy

Sep 2, 2022 · 1 like · 1 share · 108 followers View post →
every_other_evelyn
@EvelynOther · X

@C_Gardner55 @EthicalSkeptic Fasting to induce autophagy has many proponents when it comes to cancer. Dr. Been recently covered the role of caffeine in assisting the process. https://t.co/fdk1JFReCZ

Aug 18, 2022 · 14 likes · 1,077 followers View post →
Robert Keller
@findcommground · X

Caffeine and Autophagy To Reduce Fats in Liver https://t.co/SMkd5chJIy via @YouTube

Aug 17, 2022 · 2 likes · 1,201 followers View post →
Mighty Mouse
@THEMightlyMouse · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 16, 2022 · 24 shares · 1,743 followers View post →
Twinkle Crookshanks
@TwinkleCrooksh1 · X

@Bork10Bork @LauraLynnTT I know you're not incapable.. but

Aug 9, 2022 · 819 followers View post →
every_other_evelyn
@EvelynOther · X

@WhiteBoardDegen No worries. Caffeine can be good in the proper dose. https://t.co/fdk1JFReCZ

Aug 8, 2022 · 1 like · 1,077 followers View post →
luis hernan graffe
@hernangraffe · X

RT @hernangraffe: https://t.co/uYJ8QyEiHy

Aug 7, 2022 · 1 share · 3,153 followers View post →
luis hernan graffe
@hernangraffe · X

https://t.co/uYJ8QyEiHy

Aug 6, 2022 · 1 share · 3,153 followers View post →
Ruby Red
@RubyRed26847420 · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 6, 2022 · 24 shares · 1,094 followers View post →
Sherry Trett
@SherryTrett · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 6, 2022 · 24 shares · 1,803 followers View post →
Lysistrata
@Lysistr71704216 · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 5, 2022 · 24 shares · 71 followers View post →
Robert Malloy
@bobbypaintsstuf · X

Caffeine and Autophagy To Reduce Fats in Liver https://t.co/vcEhKbhx5E via @YouTube

Aug 5, 2022 · 418 followers View post →
Robin Enochs
@RobinEnochs · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 5, 2022 · 24 shares · 20,074 followers View post →
Essentials by Nature
@essentialnature · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 5, 2022 · 24 shares · 628 followers View post →
Sean Dittman, DNP
@SeanDittman · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 5, 2022 · 24 shares · 287 followers View post →
Hyun Chan Daniel Jeong
@hcdjeong · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 5, 2022 · 24 shares · 340 followers View post →
Laura Carbray
@LCarbray · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 5, 2022 · 24 shares · 9 followers View post →
Collin Doyle
@Collindoyle909 · X

https://t.co/JS1iQvIRGG

Aug 5, 2022 · 29 followers View post →
NeuroEd
@innaroz · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 5, 2022 · 24 shares · 1,612 followers View post →
wt
@lmwildthing · X

Coffee is healthy!!! ❤️ https://t.co/xsZomXuGhX

Aug 5, 2022 · 2,803 followers View post →
DrDarrellDeMello
@DarrellMello · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 5, 2022 · 24 shares · 6,334 followers View post →
Kellyanne
@Kellyan53586434 · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 5, 2022 · 24 shares · 886 followers View post →
Loofymectin aka Jan Masleid
@loofymectin · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 5, 2022 · 24 shares · 1,151 followers View post →
free radical
@BJThoenes · X

Caffeine and Autophagy To Reduce Fats in Liver https://t.co/HMMcjQ2TgW via @YouTube

Aug 5, 2022 · 1,582 followers View post →
Samuel Nyman
@SamuelNymanFI · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 5, 2022 · 24 shares · 277 followers View post →
Michelle Butler
@Jaquebelle · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 5, 2022 · 24 shares · 4,448 followers View post →
RICARDO SOUZA
@ricardorars · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 4, 2022 · 24 shares · 116 followers View post →
Renee Deitsch
@ReneeDeitsch · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 4, 2022 · 24 shares · 151 followers View post →
Kim Climer
@RhetoricalGirl0 · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 4, 2022 · 24 shares · 3,392 followers View post →
Be a refusenik. Do not comply!
@cathyslifecc · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 4, 2022 · 24 shares · 1,038 followers View post →
Lumin26
@Lumin261 · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 4, 2022 · 24 shares · 103 followers View post →
Madrynha2024
@madrynha2012 · X

RT @drbeen_medical: Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 4, 2022 · 24 shares · 3,201 followers View post →
Dr. Mobeen Syed
@drbeen_medical · X

Caffeine and Autophagy To Reduce Fats in Liver https://t.co/UMfHTupmhO

Aug 4, 2022 · 67 likes · 24 shares · 33,070 followers View post →
HB
@hennablossoms77 · X

*live* Caffeine and Autophagy To Reduce Fats in Liver https://t.co/8MaDSakL63 via @YouTube

Aug 4, 2022 · 328 followers View post →
Timechain
@TimechainP2P · X

@getbitcoin108 https://t.co/j5gCLULqs0

Apr 28, 2022 · 1,985 followers View post →
UltimApe
@ultimape · X

@MMMalign I'm not actually sure if this shows up in humans https://t.co/ZdyxbvgVYh

Sep 8, 2021 · 1 like · 6,695 followers View post →
Analyze & Optimize
@Outdoctrination · X

RT @Outdoctrination: The gut and the liver are also connected, since the liver must detoxify things that may slip through the cracks. Once…

Jun 1, 2021 · 1 share · 118,498 followers View post →
Analyze & Optimize
@Outdoctrination · X

The gut and the liver are also connected, since the liver must detoxify things that may slip through the cracks. Once again, coffee to the rescue! Caffeine has been shown to significantly reduce liver fat accumulation in animal models: https://t.co/ZCJy2f6B5a

May 31, 2021 · 5 likes · 1 share · 118,498 followers View post →
laili
@laili_lai · X

RT @Mangan150: Indeed, "caffeine surprisingly is a potent stimulator of hepatic autophagic flux" Caffeine reduces liver fat and stimulates…

Feb 26, 2021 · 6 shares · 66 followers View post →
Michael Ostrolenk, MA, MFT
@mostrolenk · X

RT @Mangan150: Indeed, "caffeine surprisingly is a potent stimulator of hepatic autophagic flux" Caffeine reduces liver fat and stimulates…

Feb 26, 2021 · 6 shares · 7,068 followers View post →
kike
@FUENTESMANZULLI · X

RT @Mangan150: Indeed, "caffeine surprisingly is a potent stimulator of hepatic autophagic flux" Caffeine reduces liver fat and stimulates…

Feb 26, 2021 · 6 shares · 249 followers View post →
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

Indeed, "caffeine surprisingly is a potent stimulator of hepatic autophagic flux" Caffeine reduces liver fat and stimulates β‐oxidation (fat burning) in hepatic cells and liver by an autophagy pathway Which means it treats fatty liver https://t.co/CTx3cgw8Zm

Feb 26, 2021 · 49 likes · 6 shares · 294,161 followers View post →