PubHawk
N Engl J Med September 2013 PMID 24047059

Long-term colorectal-cancer incidence and mortality after lower endoscopy.

Reiko Nishihara, Kana Wu, Paul Lochhead, Teppei Morikawa, Xiaoyun Liao, Zhi Rong Qian, Kentaro Inamura, Sun A Kim, Aya Kuchiba, Mai Yamauchi, Yu Imamura, Walter C Willett, Bernard A Rosner, Charles S Fuchs, Edward Giovannucci

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Mentions

126
Peak: 2 in Oct 2022
across 5 sources since Dec 2019

Extended reach

98,143
potential audience

Total likes

509

Video views

79,890

Mentions per month

Dec 2019 – Sep 2025

Where it's discussed

  • News104 articles
  • Facebook9 posts
  • Blogs6 articles
  • X / Twitter5 posts
  • YouTube2 videos

AI synopsis

What people are saying

The discussions emphasize the relevance of the study's findings, such as references to mortality benefits and screening decisions, exemplified by posts questioning if the research justifies colorectal cancer screening. The tone is cautious yet acknowledge the significance of the findings, suggesting moderate engagement and interest but not deep scrutiny.

AgreementModerate agreement

Most discussions acknowledge the importance of the study in supporting colonoscopy as a preventive measure, highlighting its benefits.

InterestModerate interest

Participants show moderate interest, focusing on practical implications like mortality benefits and screening justification.

EngagementNeutral engagement

Comments are generally brief and question-oriented, with limited in-depth analysis or detailed critique.

ImpactModerate impact

The discussions seem to recognize the study's potential influence on screening practices but do not convey a paradigm shift.

Abstract in brief

  • The study found that both colonoscopy and sigmoidoscopy significantly reduce the risk of developing colorectal cancer and dying from it, with colonoscopy offering a stronger protective effect, especially against proximal colon cancer.
  • Negative colonoscopy results are associated with a lower incidence of proximal colon cancer and reduced mortality from colorectal cancer, particularly when the procedure occurs more than 5 years before diagnosis.
  • Cancers diagnosed within 5 years after colonoscopy tend to have more aggressive molecular features, like the CpG island methylator phenotype (CIMP) and microsatellite instability, indicating that some cancers may develop rapidly despite screening.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Rashid Lui 雷諾信
@RashidLui · X

@VPrasadMDMPH @NEJM https://t.co/fFhPxPZgDO

Jun 28, 2020 · 1 like · 7,993 followers View post →
tune
@keisuke4713 · X

検査を受けた患者のrisk18%⬇️

Oct 21, 2022 · 1 like · 2 shares · 3,743 followers View post →
Rachel Issaka, MD, MAS
@IssakaMD · X

@jungleland @EvanHallMD @fredhutch @SeattleCCA Great question @jungleland! The most important outcome is mortality benefit. Many studies have demonstrated this in colon cancer screening, these are just a few: https://t.co/jBbXBGB5sd; https://t.co/FbXoBC9s1G; https://t.co/TUQKtLicdT

Dec 16, 2019 · 3,349 followers View post →
Deepak Madhu
@drdeepakmadhu · X

@sahajrathi @AustinChiangMD @drkeithsiau @stevenbollipo @DeMadaria @drabbyphilips @RashidLui Tell me if this study is enough to justify screening for colorectal cancer https://t.co/CaC46GbrjC)%20for%20distal%20colorectal%20cancers.

Jun 2, 2021 · 2,435 followers View post →

All mentions

やっさん
@kuanyi_vet · X

RT @keisuke4713: 検査を受けた患者のrisk18%⬇️

Oct 21, 2022 · 2 shares · 725 followers View post →
tune
@keisuke4713 · X

検査を受けた患者のrisk18%⬇️

Oct 21, 2022 · 1 like · 2 shares · 3,743 followers View post →
Deepak Madhu
@drdeepakmadhu · X

@sahajrathi @AustinChiangMD @drkeithsiau @stevenbollipo @DeMadaria @drabbyphilips @RashidLui Tell me if this study is enough to justify screening for colorectal cancer https://t.co/CaC46GbrjC)%20for%20distal%20colorectal%20cancers.

Jun 2, 2021 · 2,435 followers View post →
Rashid Lui 雷諾信
@RashidLui · X

@VPrasadMDMPH @NEJM https://t.co/fFhPxPZgDO

Jun 28, 2020 · 1 like · 7,993 followers View post →
Rachel Issaka, MD, MAS
@IssakaMD · X

@jungleland @EvanHallMD @fredhutch @SeattleCCA Great question @jungleland! The most important outcome is mortality benefit. Many studies have demonstrated this in colon cancer screening, these are just a few: https://t.co/jBbXBGB5sd; https://t.co/FbXoBC9s1G; https://t.co/TUQKtLicdT

Dec 16, 2019 · 3,349 followers View post →