Mentions
Extended reach
Total likes
Video views
AI synopsis
The discussions highlight several key points from the publication, such as the predictive capacity of Horvath's epigenetic clock and its correlation with biological aging. Phrases like 'actionable prevention' and 'transformative potential' reflect enthusiasm and thoughtful consideration of the implications, demonstrating how the tone varies from excitement to cautious inquiry about real-world applications.
Most discussions reflect a general agreement on the findings and their implications, though some express caution about the applications.
There is a notable level of curiosity regarding the research, as many users seek out additional information and context.
While some comments engage deeply with the methodologies and clinical applications, others tend to be more surface-level.
The perception of the findings suggests they could significantly impact the fields of developmental biology, cancer research, and aging studies.
If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing: https://t.co/BgQjKPUgIJ https://t.co/CaSiDr7AfD
Metformin improves healthspan and lifespan in mice - https://t.co/m5QSKJoIGh Metformin reduces all-cause mortality - https://t.co/IlbA1p6j61 Reprogramming to restore vision - https://t.co/DRRK1sHSUh DNA methylation age - https://t.co/z5yldxrA4Q 10/11
The following year, it was found that you could pretty accurately predict someone’s age based on a few hundred sites around the genome across several different tissue types, exciting stuff (3/?) https://t.co/IzUUXn4dOo
First, a little context. In 2013, landmark papers by Horvath and Hannum landed showing that you can predict age to within ~4 years using epigenetic data. This was exciting, but what is it useful for? https://t.co/MqPpMouuST
Horvath: Embryonic stem cells don't age https://t.co/aVZbR6ixGe - goes to the citation, also a paper from Horvath:- Horvath: They actually age. https://t.co/vjBZaVoKvF Me: 'dafuq https://t.co/WzTU2YrgDS
DNA methylation age of human tissues and cell types (2013) https://t.co/jjmSbUrmVU
This video explores the 9 hallmarks of aging, their significance, and how they impact your health. With insights into DNA methylation and its correlation with age, learn actionable solutions to mitigate rapid aging…
In this video, we will discuss aging clocks, which measure not just chronological age but biological age derived from various biomarkers. We will explore methods like the BiT age clock that enhance accuracy in…
Introducing Precious1GPT, a multimodal aging clock that combines methylation and transcriptomic data to predict biological age and identify therapeutic targets, enhancing research for age-related disease interventions.
This video explores current literature on how we can live longer, focusing on age-related NAD decline and its impact on health. It highlights ongoing research into NAD's role in age-related conditions and the challenges…
DNA methylation age of human tissues and cell types https://t.co/5dxHGm9HOM
DNA methylation age of human tissues and cell types https://t.co/5dxHGmafEk
@slavov_n As an example, Horvath’s 2013 clock had a correlation of 0.98 with age (whole blood). Even if the mechanism is unclear, its predictive capability is remarkable. https://t.co/7blbxgD8zy
Blood epigenetic clocks accelerate with metabolic/inflammatory signals—higher HbA1c, hs-CRP, IL-6 track faster DNA-methylation age. This reframes routine labs as preventive windows into aging we can act on now. Horvath 2013 https://t.co/HJykg5mqVv
RT @JScelza: Epigenetic clocks reveal biological age; but low‑grade inflammation (hs‑CRP/IL‑6) and HbA1c accelerate it, and cfDNA points to…
Epigenetic clocks reveal biological age; but low‑grade inflammation (hs‑CRP/IL‑6) and HbA1c accelerate it, and cfDNA points to which tissues. Combining blood signals shifts aging from descriptor to actionable prevention & performance. https://t.co/VSe09ZUOOi
Epigenetic clocks in blood respond to inflammation (hs-CRP, IL-6), glucose (HbA1c) and cfDNA—so blood reveals actionable aging dynamics for prevention & performance. Horvath 2013: https://t.co/HJykg5mqVv
Epigenetic clocks in blood allow reading of biological age; paired with cfDNA, HbA1c & inflammatory markers (hs-CRP, IL-6) they recast aging as a measurable, modifiable trajectory—not just years lived. Useful for prevention & performance. https://t.co/HJykg5mqVv
Epigenetic 'clocks' (DNA methylation) integrate inflammation (hs-CRP/IL‑6), glycemic load (HbA1c) and cfDNA signals—predicting biological age beyond chronological years. Reframes prevention. Horvath: https://t.co/HJykg5mqVv
Epigenetic clocks (DNA methylation) plus acute signals—cfDNA, HbA1c, hs‑CRP/IL‑6—reframe aging: a chronic biological age plus a real‑time stress readout. That enables earlier, actionable prevention. Horvath: https://t.co/VSe09ZUOOi
Epigenetic clocks (DNA methylation) reflect inflammatory burden (hs‑CRP, IL‑6) and predict mortality. Pairing clocks with cfDNA and HbA1c can reveal tissue stress before clinical disease—an earlier window for prevention. https://t.co/VSe09ZUOOi
1．Horvath S. (2013). “DNA methylation age of human tissues and cell types.” Genome Biology. ・ヒトのDNAメチル化パターンから生物学的年齢を推定するエピジェネティック時計（第1世代）を開発した論文 https://t.co/PIYKeCdFxf
@syaccoby @davidasinclair @grok @syaccoby Horvath published in Genome Biology (2013) showing DNA methylation patterns track biological aging: https://t.co/6bfRkNwHiD. His clock predicts tissue age with 96% accuracy across multiple studies.
https://t.co/8rfCiBb4Ks
https://t.co/nu7feKzmz2
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @alantomusiak: First, a little context. In 2013, landmark papers by Horvath and Hannum landed showing that you can predict age to withi…
DNA methylation age of human tissues and cell types https://t.co/1526w0dsWI
First, a little context. In 2013, landmark papers by Horvath and Hannum landed showing that you can predict age to within ~4 years using epigenetic data. This was exciting, but what is it useful for? https://t.co/MqPpMouuST
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
Se você está interessado em se aprofundar, aqui está o link para o estudo, bem como o estudo do Dr. Horvath sobre testes epigenéticos: https://t.co/kWnMZ5YoQK
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
@FitFounder Excellent post Dan! The link that you put is about DNA methylation age of human tissues and cell types only and not the full study that you described. Do you mind sharing it?
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
DNA methylation age of human tissues and cell types - PubMed https://t.co/eZvAuhVanF
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
RT @FitFounder: If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing:…
If you're interested in digging further here's the link to the study as well as Dr. Horvath's study on epigenetic testing: https://t.co/BgQjKPUgIJ https://t.co/CaSiDr7AfD
RT @agingdoc1: DNA methylation age of human tissues and cell types (2013) https://t.co/jjmSbUrmVU
DNA methylation age of human tissues and cell types - PMC https://t.co/8NkrIaUS5b
@08Juan80 @Kamalamaison @Ms_Deathwish @KatysCartoons Again a misconception. Chronological age and biological age are different. You are certainly right if you think it would be a perverse outcome to structure society on bio-age but there's actual science behind it. https://t.co/Bln5BmuQO5
Links to the mentioned clocks below: https://t.co/lOERU83m1M https://t.co/WCshvCsUmz https://t.co/QcTvyJvZuz https://t.co/B6qrAek7Ak https://t.co/aliSDk9hZB https://t.co/y2xd6SDzEG
@raphaels7 Aging and death. Pardon my earlier typo. His name is Horvath. https://t.co/7K5MzGt1mR
Sources: https://t.co/35ThkxnYS9 https://t.co/XnOtWWdfB4 https://t.co/dyoInQAjJE https://t.co/GLVb5afK2V
Original article: Horvath, S. DNA methylation age of human tissues and cell types. Genome Biol. 14, R115 (2013)
@antonioregalado @biogerontology https://t.co/9Jg8kuj8GP
Milestones of epigenetic clock https://t.co/QqpSE2eZyj
DNA methylation age of human tissues and cell types (2013) https://t.co/jjmSbUrmVU
RT @chiara_herzog: As we age, tags on our DNA (DNA methylation, 'DNAme') accumulate. These can be used to predict chronological age. One ex…
As we age, tags on our DNA (DNA methylation, 'DNAme') accumulate. These can be used to predict chronological age. One example is the Horvath clock, which is well established. https://t.co/mnQM4DUM3d 2/n
The paper for human is here: https://t.co/UB9MYYC3qQ https://t.co/oCENweWXHT
RT @davidasinclair: Metformin improves healthspan and lifespan in mice - https://t.co/m5QSKJoIGh Metformin reduces all-cause mortality - ht…
RT @davidasinclair: Metformin improves healthspan and lifespan in mice - https://t.co/m5QSKJoIGh Metformin reduces all-cause mortality - ht…
RT @davidasinclair: Metformin improves healthspan and lifespan in mice - https://t.co/m5QSKJoIGh Metformin reduces all-cause mortality - ht…
RT @davidasinclair: Metformin improves healthspan and lifespan in mice - https://t.co/m5QSKJoIGh Metformin reduces all-cause mortality - ht…
Metformin improves healthspan and lifespan in mice - https://t.co/m5QSKJoIGh Metformin reduces all-cause mortality - https://t.co/IlbA1p6j61 Reprogramming to restore vision - https://t.co/DRRK1sHSUh DNA methylation age - https://t.co/z5yldxrA4Q 10/11
@ksuhre @RArgelaguet Good question. We haven't run analysis on HeLa cells yet but I expect they will likely diverge from her chronological age at time of extraction (e.g. other cancer samples analysed at https://t.co/TUmuef1KhM).
Steve Horvath: DNA methylation age of human tissues and cell types. Genome Biol. 14, 3156 (2013). https://t.co/g0vrBWbytT https://t.co/7GoeJR9XLI
To read more about the Horvath epigenetic clock: https://t.co/tUHUAilWeB https://t.co/0gekfmttXd
RT @itscrystalgrant: The following year, it was found that you could pretty accurately predict someone’s age based on a few hundred sites a…
RT @itscrystalgrant: The following year, it was found that you could pretty accurately predict someone’s age based on a few hundred sites a…
RT @itscrystalgrant: The following year, it was found that you could pretty accurately predict someone’s age based on a few hundred sites a…
The following year, it was found that you could pretty accurately predict someone’s age based on a few hundred sites around the genome across several different tissue types, exciting stuff (3/?) https://t.co/IzUUXn4dOo
Horvath epigenetic age metric https://t.co/QEZ6ptayPX https://t.co/t4WDz8Q2s4
Horvath: Embryonic stem cells don't age https://t.co/aVZbR6ixGe - goes to the citation, also a paper from Horvath:- Horvath: They actually age. https://t.co/vjBZaVoKvF Me: 'dafuq https://t.co/WzTU2YrgDS
마음을 설레게 했던 논문 다섯개! 탐라의 연구자님들 태그합니당 ㅎㅎ #THE_NEXT_NTHROOM https://t.co/x9rhC7Yai2 https://t.co/x9rhC7Yai2 https://t.co/DLWPeF6Dy3 https://t.co/bnsniXBotq https://t.co/PB5DIk8Nce @Post_Grad_ @anneandalice031 @bokdolhihi @zozingzing @drstardust0000
RT @sandakano: @vallens @AlanBOCallaghan @amuellerml A better example: classic Horvath paper predicting age from DNA methylation features u…