More infographics from the #MVPinfographic series! This time a study from 2013 in @NEJM titled "Targeted Temperature Management at 33°C vs. 36°C after Cardiac Arrest." #FOAMed #infographic Full infographic: https://t.co/AnD34m6g2N Full paper: https://t.co/J4DEkD9aL2 https://t.co/gC7LklMuxR
Targeted temperature management at 33°C versus 36°C after cardiac arrest.
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Feb 2019 – Aug 2025Where it's discussed
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X / Twitter93 posts
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Facebook92 posts
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Blogs39 articles
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News17 articles
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Reddit3 posts
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YouTube2 videos
AI synopsis
What people are saying
The collective discussions show a keen interest in understanding the trial's implications, with posts mentioning terms like 'no difference,' 'clinical practice,' and 'hypothermia,' reflecting a deep engagement with the research's clinical significance. The use of phrases such as 'reversed by Nielsen trial' and 'changing practice' highlights both the relevance and the transformative potential of the study's findings.
Most discussions acknowledge the 2013 NEJM study's finding that targeting different temperatures after cardiac arrest yields similar outcomes, showing general consensus.
The posts demonstrate high curiosity and engagement, referencing the original trial, subsequent studies, and clinical practice implications.
Many posts analyze the study's methodology, cite related research, and question clinical practices, indicating active engagement.
Discussions reflect recognition that the trial influenced treatment strategies and that the findings could alter guidelines or clinical decision-making.
Abstract in brief
- Unconscious survivors of out-of-hospital cardiac arrest face a high risk of death or poor neurological outcomes, and therapeutic hypothermia is recommended but its effectiveness at different target temperatures is unclear.
- In a trial involving 950 patients, researchers compared outcomes of target temperatures at 33°C and 36°C, focusing on all-cause mortality and neurological function at 180 days.
- The results showed no significant difference in mortality or neurological outcomes between the two temperature groups, suggesting that targeting either temperature may have similar effects on patient survival and function after cardiac arrest.
Top posts
Most liked on X and Bluesky#CHESTChat T1: TTM in TBI/OHCA, In TBI: Eurotherm3235 no difference in outcome notmothermia versus TTM https://t.co/v9wfWVrYmu TTM trial: OHCA 33 versus 36-fever prevention is good https://t.co/LodWn57d5l Hyperion: it’s cool to be cool again OHCA 33 https://t.co/BUyABgJ5rw
Unlike the planet, it looks like we may be going cold. Again. For non-shockable at least. https://t.co/gt12zoElyI https://t.co/WOsHhqMtc8
(1/2) #AnesJC 4th Abstract: Neilsen 2013 @NEJM #meded https://t.co/UxxjQy5mOe https://t.co/gJZwucpAIA
NEJM 2013 33℃ vs. 36℃ https://t.co/exx3690juz
5/ Studies with negative findings can have immediate effects on clinical practice. Even if #TTMtrial did not have negative results (similar outcomes between 36°C and 33°C), it seems to have been interpreted negatively.
All mentions
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Emergency Medicine PG's Exam Question -TTM Trial - Targeted Temperature Management at 33°C versus 36°C after Cardiac Arrest by Dr. Vasanth. K on the RAAONLINE App. Android: https://t.co/fSlaHVpc0T IOS:https://t.co/oJAMS4dSCa Contact: +91-9994994266 #raaonline #freelecture https://t.co/lGI6d2Suv2
Emergency Medicine PG's Exam Question -TTM Trial - Targeted Temperature Management at 33°C versus 36°C after Cardiac Arrest by Dr. Vasanth. K on the RAAONLINE App. Android: https://t.co/fSlaHVoEbl IOS: https://t.co/oJAMS4dkMC Contact: +91-9994994266 #raaonline #freelecture https://t.co/DJX0b5l9nv
@TheSGEM @ross_prager @IM_Crit_ @EM_RESUS @PulmCrit @emcrit @katiewiskar @nickmmark @First10EM https://t.co/Erqs9GYBav https://t.co/jWSM6Ay58R
@Paul_Wischmeyer @NEJM @lancet @TheLancet TTM https://t.co/eHhhSzp4Xa 3 SITES https://t.co/Ye3HT0Yw7u FLORALI https://t.co/vYpacvRb5x SAPS https://t.co/hn0GpNolID
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxg8RqT
2013: Enter the #TTM-trial. HTTPS://10.1056/NEJMoa1310519 939 patients resuscitated after OHCA were randomly assigned to 33°C or 36°C for 24 h. Prevention of fever for the first 72 h was attempted in both groups (this is important. Remember this)
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxg8RqT
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
@stephanamayer @NEJM It was reversed by the Nielsen trial in 2013 https://t.co/UIlq73XEDD
After the study titled as “ Targeted Temperature Management at 33°C versus 36°C after Cardiac Arrest” previously published in 2013 and showed no difference in both - https://t.co/nRrlPUjh06
NEJM 2013 33℃ vs. 36℃ https://t.co/exx3690juz
RT @dr_mattmorgan: Researchers have been trying to find the best "dose" of cooling to use for nearly twenty years. The TTM1 study in 2013 s…
@CritCareReviews @emcrit @PulmCrit @adamdavidthomas @nielsen_niklas presenting results @ttm2trial now join the livestream #SCCMSoME https://t.co/OZA9YsEcX0 Low numbers, lack of certainty hence need for TTM https://t.co/XlOnsxEJ5H #CHESTTrainees @neurocritical
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
RT @tscquizzato: 5/ Studies with negative findings can have immediate effects on clinical practice. Even if #TTMtrial did not have negat…
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
RT @tscquizzato: 5/ Studies with negative findings can have immediate effects on clinical practice. Even if #TTMtrial did not have negat…
5/ Studies with negative findings can have immediate effects on clinical practice. Even if #TTMtrial did not have negative results (similar outcomes between 36°C and 33°C), it seems to have been interpreted negatively.
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxg8RqT
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
@__ice9 @ProfMakris YES, massive bleeding in trauma [https://t.co/SpH37TeEnQ], cardiac arrest [https://t.co/dXcfQavW7q], major bleeding in emergency surgery [https://t.co/VbEDEEmE1s] Dep on legislation in country executing, ie community consent (US) or Surrogate Consent/Scientific guardian (Europe)
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM - 2013 - 33 vs 36oC after CA - ∅mortality or neurological outcome - https://t.co/CYiDxgqsPt
TTM Trial https://t.co/1VNcwvBYQI
Starting the #CCMJC a little late today (yay night float! #frontline) - only 2 articles for tonight friends. Let's start by discussing hypothermia after cardiac arrest. #surgicalcriticalcare #SoMe4Surgery #critcaremed #CriticalCare #surgicaleducation https://t.co/urzUeseIh5
@shinybluedress @martinjamescook @NishNath90 @ubergasmonkey The first targeted temperature management trial. 900 patients, no difference. https://t.co/Gjhonor6Yd
@iwashyna @JBLascarrou I'm curious to hypothesis of hypothermia to 33 was tested vs. 36. https://t.co/tBP7EKOZjC <-- This out in 2013 changed my practice pattern and now i'm back to being confounded to 33.
RT @drdangayach: #CHESTChat T1: TTM in TBI/OHCA, In TBI: Eurotherm3235 no difference in outcome notmothermia versus TTM https://t.co/v9wfW…
RT @drdangayach: #CHESTChat T1: TTM in TBI/OHCA, In TBI: Eurotherm3235 no difference in outcome notmothermia versus TTM https://t.co/v9wfW…
RT @drdangayach: #CHESTChat T1: TTM in TBI/OHCA, In TBI: Eurotherm3235 no difference in outcome notmothermia versus TTM https://t.co/v9wfW…
RT @drdangayach: #CHESTChat T1: TTM in TBI/OHCA, In TBI: Eurotherm3235 no difference in outcome notmothermia versus TTM https://t.co/v9wfW…
RT @drdangayach: #CHESTChat T1: TTM in TBI/OHCA, In TBI: Eurotherm3235 no difference in outcome notmothermia versus TTM https://t.co/v9wfW…
RT @drdangayach: #CHESTChat T1: TTM in TBI/OHCA, In TBI: Eurotherm3235 no difference in outcome notmothermia versus TTM https://t.co/v9wfW…
RT @drdangayach: #CHESTChat T1: TTM in TBI/OHCA, In TBI: Eurotherm3235 no difference in outcome notmothermia versus TTM https://t.co/v9wfW…
RT @drdangayach: #CHESTChat T1: TTM in TBI/OHCA, In TBI: Eurotherm3235 no difference in outcome notmothermia versus TTM https://t.co/v9wfW…
RT @drdangayach: #CHESTChat T1: TTM in TBI/OHCA, In TBI: Eurotherm3235 no difference in outcome notmothermia versus TTM https://t.co/v9wfW…
#CHESTChat T1: TTM in TBI/OHCA, In TBI: Eurotherm3235 no difference in outcome notmothermia versus TTM https://t.co/v9wfWVrYmu TTM trial: OHCA 33 versus 36-fever prevention is good https://t.co/LodWn57d5l Hyperion: it’s cool to be cool again OHCA 33 https://t.co/BUyABgJ5rw
@malamo512 @AndreaMElliott1 @pghpanther Hard to say.. some would argue why 33 was used instead of 36. With higher targets is it truly targeted temperature management or a fever avoidance strategy that matters?
Targeted Temperature Management at 33°C versus 36°C after Cardiac Arrest | NEJM https://t.co/3LOUFNuFWY
RT @psirides: Unlike the planet, it looks like we may be going cold. Again. For non-shockable at least. https://t.co/gt12zoElyI https://t.c…
RT @psirides: Unlike the planet, it looks like we may be going cold. Again. For non-shockable at least. https://t.co/gt12zoElyI https://t.c…
RT @psirides: Unlike the planet, it looks like we may be going cold. Again. For non-shockable at least. https://t.co/gt12zoElyI https://t.c…
RT @psirides: Unlike the planet, it looks like we may be going cold. Again. For non-shockable at least. https://t.co/gt12zoElyI https://t.c…
Prior to application, we have to choose the target wisely. They EXCLUDE 1.Unwitnessed cardiac arrest w/ initial rhythm asystole 2.SBP<80 despite circulatory supports. https://t.co/LTuMZzIOM7
RT @psirides: Unlike the planet, it looks like we may be going cold. Again. For non-shockable at least. https://t.co/gt12zoElyI https://t.c…
RT @psirides: Unlike the planet, it looks like we may be going cold. Again. For non-shockable at least. https://t.co/gt12zoElyI https://t.c…
Unlike the planet, it looks like we may be going cold. Again. For non-shockable at least. https://t.co/gt12zoElyI https://t.co/WOsHhqMtc8
RT @Duke_Anesthesia: (1/2) #AnesJC 4th Abstract: Neilsen 2013 @NEJM #meded https://t.co/UxxjQy5mOe https://t.co/gJZwucpAIA
RT @Duke_Anesthesia: (1/2) #AnesJC 4th Abstract: Neilsen 2013 @NEJM #meded https://t.co/UxxjQy5mOe https://t.co/gJZwucpAIA
RT @Duke_Anesthesia: (1/2) #AnesJC 4th Abstract: Neilsen 2013 @NEJM #meded https://t.co/UxxjQy5mOe https://t.co/gJZwucpAIA
RT @Duke_Anesthesia: (1/2) #AnesJC 4th Abstract: Neilsen 2013 @NEJM #meded https://t.co/UxxjQy5mOe https://t.co/gJZwucpAIA
RT @Duke_Anesthesia: (1/2) #AnesJC 4th Abstract: Neilsen 2013 @NEJM #meded https://t.co/UxxjQy5mOe https://t.co/gJZwucpAIA
(1/2) #AnesJC 4th Abstract: Neilsen 2013 @NEJM #meded https://t.co/UxxjQy5mOe https://t.co/gJZwucpAIA
RT @WeAreCanadiEM: More infographics from the #MVPinfographic series! This time a study from 2013 in @NEJM titled "Targeted Temperature Man…
RT @WeAreCanadiEM: More infographics from the #MVPinfographic series! This time a study from 2013 in @NEJM titled "Targeted Temperature Man…
RT @WeAreCanadiEM: More infographics from the #MVPinfographic series! This time a study from 2013 in @NEJM titled "Targeted Temperature Man…
RT @WeAreCanadiEM: More infographics from the #MVPinfographic series! This time a study from 2013 in @NEJM titled "Targeted Temperature Man…
RT @WeAreCanadiEM: More infographics from the #MVPinfographic series! This time a study from 2013 in @NEJM titled "Targeted Temperature Man…
RT @WeAreCanadiEM: More infographics from the #MVPinfographic series! This time a study from 2013 in @NEJM titled "Targeted Temperature Man…
RT @WeAreCanadiEM: More infographics from the #MVPinfographic series! This time a study from 2013 in @NEJM titled "Targeted Temperature Man…
RT @WeAreCanadiEM: More infographics from the #MVPinfographic series! This time a study from 2013 in @NEJM titled "Targeted Temperature Man…
RT @WeAreCanadiEM: More infographics from the #MVPinfographic series! This time a study from 2013 in @NEJM titled "Targeted Temperature Man…
RT @WeAreCanadiEM: More infographics from the #MVPinfographic series! This time a study from 2013 in @NEJM titled "Targeted Temperature Man…
RT @WeAreCanadiEM: More infographics from the #MVPinfographic series! This time a study from 2013 in @NEJM titled "Targeted Temperature Man…
RT @WeAreCanadiEM: More infographics from the #MVPinfographic series! This time a study from 2013 in @NEJM titled "Targeted Temperature Man…
RT @WeAreCanadiEM: More infographics from the #MVPinfographic series! This time a study from 2013 in @NEJM titled "Targeted Temperature Man…
RT @WeAreCanadiEM: More infographics from the #MVPinfographic series! This time a study from 2013 in @NEJM titled "Targeted Temperature Man…
RT @WeAreCanadiEM: More infographics from the #MVPinfographic series! This time a study from 2013 in @NEJM titled "Targeted Temperature Man…
RT @WeAreCanadiEM: More infographics from the #MVPinfographic series! This time a study from 2013 in @NEJM titled "Targeted Temperature Man…
More infographics from the #MVPinfographic series! This time a study from 2013 in @NEJM titled "Targeted Temperature Management at 33°C vs. 36°C after Cardiac Arrest." #FOAMed #infographic Full infographic: https://t.co/AnD34m6g2N Full paper: https://t.co/J4DEkD9aL2 https://t.co/gC7LklMuxR
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