PubHawk
March 2014 PMID 24382640

Paradoxical adipose hyperplasia after cryolipolysis.

H Ray Jalian, Mathew M Avram, Lilit Garibyan, Martin C Mihm, R Rox Anderson

Full text PDF Download social card

Mentions

125
Peak: 11 in Oct 2021
across 4 sources since Oct 2019

Extended reach

243,463
potential audience

Total likes

2,507

Video views

40,617

Mentions per month

Oct 2019 – Sep 2025

Where it's discussed

  • News75 articles
  • X / Twitter44 posts
  • Blogs4 articles
  • YouTube2 videos

AI synopsis

What people are saying

The discussions demonstrate a high level of concern and engagement, with examples like mentions of the incidence rate, treatment options, and advice from experts, indicating the importance and relevance of the publication's findings for practitioners and potential patients. Words like 'serious,' 'safety,' and 'guidance' contribute to a tone emphasizing concern and the need for further research or caution.

AgreementModerate agreement

Most discussions acknowledge the seriousness of paradoxical adipose hyperplasia and support continued research or caution, indicating general agreement on the significance of the issue.

InterestHigh interest

Given the focus on safety concerns, incidence, and clinical implications, the discussions show high interest among professionals and concerned individuals.

EngagementModerate engagement

Participants reference research studies, clinical reviews, and expert opinions, reflecting moderate but meaningful engagement with the topic.

ImpactModerate impact

The discussions highlight potential safety risks and the importance of proper procedures, suggesting some impact on clinical practices and patient safety awareness.

Abstract in brief

  • Cryolipolysis is a noninvasive procedure used to reduce fat by cooling the targeted area, with over 650,000 treatments performed worldwide.
  • A rare side effect called paradoxical adipose hyperplasia can occur, where instead of losing fat, the treated area enlarges due to an increase in fat tissue, as seen in a case of a man in his 40s.
  • The condition has an incidence of around 0.51%, appears more common in men, and currently has no known risk factors or evidence of spontaneous resolution, requiring further research to understand its cause.]
Read the full abstract

Top posts

Most liked on X and Bluesky
Winter❄️
@w1n732n4 · X

Paradoxical Adipose Hyperplasia After Cryolipolysis (CoolScalpting®) 皮下脂肪を冷却し、アポトーシスに誘導する美容医療後の稀な合併症 施術数ヶ月後に脂肪増生 術部に限局して硬く膨隆 しばしばアプリケーターに沿う (バタースティック状)

Sep 2, 2025 · 39 likes · 5 shares · 251 followers View post →
Plastic and Reconstructive Surgery
@prsjournal · X

Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified in 510 Patients https://t.co/WukfwdXeql #plasticsurgery #PRSJournal https://t.co/xO5W9yXjMu

Oct 1, 2021 · 22 likes · 9 shares · 23,430 followers View post →
Plastic and Reconstructive Surgery
@prsjournal · X

Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified in 510 Patients https://t.co/L3KgzTFt0J #plasticsurgery #PRSJournal https://t.co/H2zyoawD6u

Apr 27, 2023 · 20 likes · 6 shares · 23,430 followers View post →
Plastic and Reconstructive Surgery
@prsjournal · X

Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified in 510 Patients https://t.co/HvfCDRMS8U #plasticsurgery #PRSJournal https://t.co/zU2CPUjpuR

Feb 27, 2022 · 20 likes · 9 shares · 23,430 followers View post →
Aesthetic Surgery Journal/ASJ Open Forum
@ASJrnl · X

#PlasticSurgery podcasts!

Sep 7, 2021 · 7 likes · 5 shares · 12,706 followers View post →
Stanford Plastic Surgery
@StanfordPlastic · X

Sep 5, 2022 · 5 likes · 1 share · 5,089 followers View post →

All mentions

パズドラー@デュエルリンクス
@cardcollect · X

RT @w1n732n4: Paradoxical Adipose Hyperplasia After Cryolipolysis (CoolScalpting®) 皮下脂肪を冷却し、アポトーシスに誘導する美容医療後の稀な合併症 施術数ヶ月後に脂肪増生 術部に限局して硬く膨隆…

Sep 2, 2025 · 5 shares · 179 followers View post →
太郎
@taro_RFLN · X

RT @w1n732n4: Paradoxical Adipose Hyperplasia After Cryolipolysis (CoolScalpting®) 皮下脂肪を冷却し、アポトーシスに誘導する美容医療後の稀な合併症 施術数ヶ月後に脂肪増生 術部に限局して硬く膨隆…

Sep 2, 2025 · 5 shares · 208 followers View post →
enlight☢
@enlight524 · X

RT @w1n732n4: Paradoxical Adipose Hyperplasia After Cryolipolysis (CoolScalpting®) 皮下脂肪を冷却し、アポトーシスに誘導する美容医療後の稀な合併症 施術数ヶ月後に脂肪増生 術部に限局して硬く膨隆…

Sep 2, 2025 · 5 shares · 1,178 followers View post →
Winter❄️
@w1n732n4 · X

Paradoxical Adipose Hyperplasia After Cryolipolysis (CoolScalpting®) 皮下脂肪を冷却し、アポトーシスに誘導する美容医療後の稀な合併症 施術数ヶ月後に脂肪増生 術部に限局して硬く膨隆 しばしばアプリケーターに沿う (バタースティック状)

Sep 2, 2025 · 39 likes · 5 shares · 251 followers View post →
Adipose Papers
@adipose_papers · X

Paradoxical Adipose Hyperplasia after Cryolipolysis CoolSculpting https://t.co/iCCM7DlfDV https://t.co/VysKOiWSBc

Aug 15, 2023 · 2,468 followers View post →
Orange987
@Delia_987 · X

RT @prsjournal: Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified i…

Jun 24, 2023 · 6 shares · 38 followers View post →
Bitwellness
@beautyevidence · X

RT @prsjournal: Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified i…

Apr 27, 2023 · 6 shares · 2,949 followers View post →
Rami S. Kantar, MD, MPH, PhD
@RamiKantar1 · X

RT @prsjournal: Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified i…

Apr 27, 2023 · 6 shares · 3,241 followers View post →
Roy Kim
@drroykim · X

RT @prsjournal: Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified i…

Apr 27, 2023 · 6 shares · 14,890 followers View post →
Plastic and Reconstructive Surgery
@prsjournal · X

Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified in 510 Patients https://t.co/L3KgzTFt0J #plasticsurgery #PRSJournal https://t.co/H2zyoawD6u

Apr 27, 2023 · 20 likes · 6 shares · 23,430 followers View post →
Stanford Surgery
@StanfordSurgery · X

RT @StanfordPlastic:

Sep 6, 2022 · 1 share · 8,698 followers View post →
Stanford Plastic Surgery
@StanfordPlastic · X

Sep 5, 2022 · 5 likes · 1 share · 5,089 followers View post →
Adipose Papers
@adipose_papers · X

Characteristics and Treatment of Patients Diagnosed With Paradoxical Adipose Hyperplasia After Cryolipolysis: A Case Series and Scoping Review https://t.co/6K5d9Atxki https://t.co/83lor45Z57

Aug 12, 2022 · 2,468 followers View post →
Adipose Papers
@adipose_papers · X

Commentary on: Characteristics and Treatment of Patients Diagnosed With Paradoxical Adipose Hyperplasia After Cryolipolysis: A Case Series and Scoping Review https://t.co/sDTudojDuC https://t.co/eVhsjENy4I

Aug 12, 2022 · 2,468 followers View post →
katherin campo J
@katherincj · X

RT @prsjournal: Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified i…

Feb 28, 2022 · 9 shares · 211 followers View post →
Elie Ramly, MD
@elieramly · X

RT @prsjournal: Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified i…

Feb 28, 2022 · 9 shares · 776 followers View post →
Dr. Muriu Kinuthia
@Muriu · X

RT @prsjournal: Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified i…

Feb 28, 2022 · 9 shares · 1,931 followers View post →
Maria T. Huayllani
@mariahuayllanip · X

RT @prsjournal: Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified i…

Feb 27, 2022 · 9 shares · 179 followers View post →
Doctora Palacios
@DoctoraPalacios · X

RT @prsjournal: Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified i…

Feb 27, 2022 · 9 shares · 358 followers View post →
Rami S. Kantar, MD, MPH, PhD
@RamiKantar1 · X

RT @prsjournal: Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified i…

Feb 27, 2022 · 9 shares · 3,241 followers View post →
Doctor Sekzi ❓️⭐⭐⭐
@DoctorSekzi · X

RT @prsjournal: Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified i…

Feb 27, 2022 · 9 shares · 9,128 followers View post →
Plastic and Reconstructive Surgery
@prsjournal · X

Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified in 510 Patients https://t.co/HvfCDRMS8U #plasticsurgery #PRSJournal https://t.co/zU2CPUjpuR

Feb 27, 2022 · 20 likes · 9 shares · 23,430 followers View post →
Next Steps in Derm
@NextSteps_Derm · X

@JDDONline author Dr. Jared Jagdeo provides his take on Linda Evangelista’s recent admission that she developed paradoxical adipose hyperplasia after #cryolipolysis, as well as guidance for how dermatologists should counsel their cryolipolysis patients. https://t.co/uSkRMWT7kE

Oct 9, 2021 · 1 like · 1,028 followers View post →
SCALE
@scalemusiccity · X

After model Linda Evangelista shared her experience with Coolscuplting and paradoxical adipose hyperplasia (PAH), some have become skeptical of the procedure's safety. The bottom line? ALWAYS go to a licensed and trained professional! https://t.co/Yt4es4Rd12

Oct 4, 2021 · 199 followers View post →
Ara Salibian
@AraSalibianMD · X

RT @prsjournal: Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified i…

Oct 2, 2021 · 9 shares · 1,901 followers View post →
Joshua M Cohen
@DrJoshuaCohen · X

RT @prsjournal: Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified i…

Oct 2, 2021 · 9 shares · 166 followers View post →
Dr. Angel Facio
@Dr_Facio · X

RT @prsjournal: Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified i…

Oct 1, 2021 · 9 shares · 62 followers View post →
Patel Plastic Surgery
@drpatelplastics · X

RT @prsjournal: Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified i…

Oct 1, 2021 · 9 shares · 658 followers View post →
Bitwellness
@beautyevidence · X

RT @prsjournal: Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified i…

Oct 1, 2021 · 9 shares · 2,949 followers View post →
lenin Garcia
@doctorlening · X

RT @prsjournal: Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified i…

Oct 1, 2021 · 9 shares · 429 followers View post →
Rami S. Kantar, MD, MPH, PhD
@RamiKantar1 · X

RT @prsjournal: Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified i…

Oct 1, 2021 · 9 shares · 3,241 followers View post →
Roy Kim
@drroykim · X

RT @prsjournal: Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified i…

Oct 1, 2021 · 9 shares · 14,890 followers View post →
Plastic and Reconstructive Surgery
@prsjournal · X

Trending in PRS: Paradoxical Adipose Hyperplasia after Cryolipolysis: A Report on Incidence and Common Factors Identified in 510 Patients https://t.co/WukfwdXeql #plasticsurgery #PRSJournal https://t.co/xO5W9yXjMu

Oct 1, 2021 · 22 likes · 9 shares · 23,430 followers View post →
NELLONALEE
@Margare63837245 · X

Paradoxical Adipose Hyperplasia After Cryolipolysis https://t.co/t7t2VFHsyn

Sep 23, 2021 · 502 followers View post →
Jeffrey Gusenoff, MD
@jgusenoff · X

RT @ASJrnl: #PlasticSurgery podcasts!

Sep 7, 2021 · 5 shares · 607 followers View post →
Grant Stevens, MD
@DrGrantStevens · X

RT @ASJrnl: #PlasticSurgery podcasts!

Sep 7, 2021 · 5 shares · 5,409 followers View post →
Marco Gomez Diaz
@antoniosurgery · X

RT @ASJrnl: #PlasticSurgery podcasts!

Sep 7, 2021 · 5 shares · 504 followers View post →
Bitwellness
@beautyevidence · X

RT @ASJrnl: #PlasticSurgery podcasts!

Sep 7, 2021 · 5 shares · 2,949 followers View post →
Roy Kim
@drroykim · X

RT @ASJrnl: #PlasticSurgery podcasts!

Sep 7, 2021 · 5 shares · 14,890 followers View post →
Aesthetic Surgery Journal/ASJ Open Forum
@ASJrnl · X

#PlasticSurgery podcasts!

Sep 7, 2021 · 7 likes · 5 shares · 12,706 followers View post →
佐々木翔一(美容外科医)
@shoichi_sasaki · X

出典；JAMA　Dermatology Paradoxical Adipose Hyperplasia After Cryolipolysis H. Ray Jalian, MD; Mathew M. Avram, MD, JD; Lilit Garibyan, MD, PhD; Martin C. Mihm, MD; R. Rox Anderson, MD

Jun 20, 2021 · 6,568 followers View post →
Adipose Papers
@adipose_papers · X

Response to "Shockwave Therapy for the Prevention of Paradoxical Adipose Hyperplasia After Cryolipolysis: Myth or Reality?" https://t.co/UYvTtomXtN https://t.co/SSldqkaYnD

Apr 22, 2021 · 2,468 followers View post →
VASPS
@spsva · X

The Biennial Meeting starts TODAY at 1 p.m. From Managing Botulinum Toxin Reconstitution Regulations in My Practice to Paradoxical Adipose Hyperplasia After Cryolipolysis we have an educational program planned that you do not want to miss! https://t.co/l3s67yFNNP

Nov 22, 2019 · 6 followers View post →
VASPS
@spsva · X

Register Now and Save $100! During the VASPS 2019 Biennial Meeting Dr. Thomas Hubbard and Dr. Helena Guarda will review the data on complications that can arise from Paradoxical Adipose Hyperplasia After Cryolipolysis procedures and their treatment options.https://t.co/JF5TIXnVHJ https://t.co/QeIWHil5RW

Oct 14, 2019 · 1 like · 6 followers View post →