Hum Psychopharmacol January 2014 PMID 24424706

A meta-analysis of inositol for depression and anxiety disorders.

Tomohiko Mukai, Taro Kishi, Yuki Matsuda, Nakao Iwata

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Abstract in brief

This meta-analysis evaluated the effectiveness of inositol, a supplement, in treating depression and anxiety disorders by reviewing multiple randomized controlled trials (RCTs) from various databases up to August 2013.
The results showed no significant overall benefits of inositol on depression, anxiety, or OCD symptoms, although there was a slight trend indicating more responders in depression and some evidence suggesting potential benefits for premenstrual dysphoric disorder (PMDD).
The study concluded that inositol might help depressed patients, especially those with PMDD, but the findings are limited due to the small number of studies included and no strong evidence of significant effects.]

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