June 1988 PMID 2455231

Human basophil degranulation triggered by very dilute antiserum against IgE.

E Davenas, F Beauvais, J Amara, M Oberbaum, B Robinzon, A Miadonna, A Tedeschi, B Pomeranz, P Fortner, P Belon

Mentions

52
Peak: 3 in Mar 2025
across 5 sources since Jun 2018

Extended reach

56,570
potential audience

Total likes

170

Video views

6,093

Mentions per month

Jun 2018 – Mar 2025

Where it's discussed

  • Blogs17 articles
  • X / Twitter14 posts
  • News14 articles
  • Facebook5 posts
  • YouTube2 videos

AI synopsis

What people are saying

The overall tone reflects skepticism and curiosity, with users quoting the original study, questioning its methodology, and recalling its historical controversy, especially emphasizing phrases like 'físicamente 100% descabida' and references to its publication in a prestigious journal, which underline the ongoing debate about its validity and impact.

AgreementLow agreement

Most discussions question the validity of the findings and express skepticism about the water memory concept, indicating mild disagreement.

InterestModerate interest

Users show curiosity and interest, referencing the controversial nature of the research and its implications.

EngagementModerate engagement

Several participants actively debate and reference specific experiments, critiques, and historical contexts, demonstrating moderate engagement.

ImpactModerate impact

The discussions highlight the paper's influence on debates about scientific credibility and the water memory hypothesis, implying moderate impact.

Abstract in brief

  • The study explores how human basophils, a type of white blood cell, release histamine when exposed to very diluted anti-IgE antibodies, with effects seen across an extremely wide range of dilutions.
  • Despite the high dilutions where anti-IgE molecules are believed to be absent, the cells still show peaks of degranulation, suggesting a possible non-traditional mechanism, potentially linked to the water’s molecular organization.
  • The observed effects require vigorous shaking of the solutions, hinting that the biological response might be influenced by the physical process of dilution and mixing, rather than the presence of actual antibodies.]

Top posts

Most liked on X and Bluesky
apetp
@apetp_ · X

@JeanBacino @StopPseudo @MedicAcupuntura @TaitaroBnS @mrosastw @pelodytes @VaryIngweion Sí, el infame artículo de Benaviste, publicado en nature, donde "demuestra" el mecanismo de la homeopatía: https://t.co/uG4c0E4ujP Me sorprende que no lo conozca, este artículo ha sido bastante famoso.

Sep 9, 2022 · 4 likes · 13,563 followers View post →
IntegralAnswers
@IntegralAnswers · X

2/ Benveniste’s team reported that human basophils degranulated (released histamine) in response to anti-IgE antibodies that had been serially diluted beyond Avogadro’s limit—meaning no molecules were likely left. Nature (1988): https://t.co/dddDES9qmR

Mar 22, 2025 · 4 likes · 2 shares · 8,591 followers View post →
Nicolas Govin
@tabaco_logic · X

Thread mémoire de l'eau : 1. En 1988, Jacques Benveniste publie dans Nature : "Human basophil degranulation triggered by very dilute antiserum against IgE". Il y affirme que des solutions d'IG, diluées au-delà du nbre d'Avogadro, provoquent une réaction des basophiles humains. https://t.co/rwTsl3bCRh

Feb 20, 2025 · 2 likes · 1,744 followers View post →
Meithan West
@meithan42 · X

@jm4change @_Sheethal_ That's not true. There *has* been scientific research on the topic. Most of it either later turns out to be low quality, e.g. [1], or find only a tiny effect, maybe just placebo; see e.g. [2]. After a while one learns. [1] https://t.co/WKh7Iddr9B [2] https://t.co/muOvBIXVGA

Jul 4, 2021 · 2 likes · 1,234 followers View post →
Carlos E Alvarez
@CarlosEAlvare17 · X

@jlindcary @StephenABoydPh1 @strangetruther @CapRadioNews Don't pooh-pooh water,

Dec 20, 2023 · 2 likes · 1,166 followers View post →
Bruce Halford
@bruce_halford · X

@sadhak_1111 @spandan108 @LuitelBibhu Human Basophil Degranulation Triggered By Very Dilute Antiserum Against IgE. The first paper ever in which it was proposed that water had memory, authored by Benveniste et al. It was published in Nature. https://t.co/FCuvz0t7VX (Use scihub if u wanna read it.)

Aug 28, 2021 · 1 like · 7 followers View post →

All mentions

Maegan Laporte unacceptable independent
@maegan_laporte · X

RT @IntegralAnswers: 2/ Benveniste’s team reported that human basophils degranulated (released histamine) in response to anti-IgE antibodie…

Mar 22, 2025 · 2 shares · 5,608 followers View post →
Based Neanderthal
@NiceNeanderthal · X

RT @IntegralAnswers: 2/ Benveniste’s team reported that human basophils degranulated (released histamine) in response to anti-IgE antibodie…

Mar 22, 2025 · 2 shares · 1,969 followers View post →
IntegralAnswers
@IntegralAnswers · X

2/ Benveniste’s team reported that human basophils degranulated (released histamine) in response to anti-IgE antibodies that had been serially diluted beyond Avogadro’s limit—meaning no molecules were likely left. Nature (1988): https://t.co/dddDES9qmR

Mar 22, 2025 · 4 likes · 2 shares · 8,591 followers View post →
Nicolas Govin
@tabaco_logic · X

Thread mémoire de l'eau : 1. En 1988, Jacques Benveniste publie dans Nature : "Human basophil degranulation triggered by very dilute antiserum against IgE". Il y affirme que des solutions d'IG, diluées au-delà du nbre d'Avogadro, provoquent une réaction des basophiles humains. https://t.co/rwTsl3bCRh

Feb 20, 2025 · 2 likes · 1,744 followers View post →
Daniel Corcos
@daniel_corcos · X

Les résultats de cette étude invraisemblable ont été publiés dans la prestigieuse revue Nature. https://t.co/fAfcTPNzWn 7/

Feb 24, 2024 · 6,961 followers View post →
Carlos E Alvarez
@CarlosEAlvare17 · X

@jlindcary @StephenABoydPh1 @strangetruther @CapRadioNews Don't pooh-pooh water,

Dec 20, 2023 · 2 likes · 1,166 followers View post →
apetp
@apetp_ · X

@JeanBacino @StopPseudo @MedicAcupuntura @TaitaroBnS @mrosastw @pelodytes @VaryIngweion Sí, el infame artículo de Benaviste, publicado en nature, donde "demuestra" el mecanismo de la homeopatía: https://t.co/uG4c0E4ujP Me sorprende que no lo conozca, este artículo ha sido bastante famoso.

Sep 9, 2022 · 4 likes · 13,563 followers View post →
Bruce Halford
@bruce_halford · X

@Sailendra01 Human Basophil Degranulation Triggered By Very Dilute Antiserum Against IgE. The first paper ever in which it was proposed that water had memory, authored by Benveniste et al. It was published in Nature. https://t.co/FCuvz0t7VX (Use scihub if u wanna read it.)

Aug 29, 2021 · 7 followers View post →
Bruce Halford
@bruce_halford · X

@sadhak_1111 @spandan108 @LuitelBibhu Human Basophil Degranulation Triggered By Very Dilute Antiserum Against IgE. The first paper ever in which it was proposed that water had memory, authored by Benveniste et al. It was published in Nature. https://t.co/FCuvz0t7VX (Use scihub if u wanna read it.)

Aug 28, 2021 · 1 like · 7 followers View post →
Meithan West
@meithan42 · X

@jm4change @_Sheethal_ That's not true. There *has* been scientific research on the topic. Most of it either later turns out to be low quality, e.g. [1], or find only a tiny effect, maybe just placebo; see e.g. [2]. After a while one learns. [1] https://t.co/WKh7Iddr9B [2] https://t.co/muOvBIXVGA

Jul 4, 2021 · 2 likes · 1,234 followers View post →
NumCracker
@CrackerNum · X

@leandrotessler Sou mais cético com tais periódicos, Leandro! Na era Maddox a Nature publicou o clássico artigo de Jacques Benveniste. Mas a hipótese homeopática é fisicamente 100% descabida: por que então publicaram sem antes replicar? https://t.co/BsJVxrbtWu https://t.co/mjHr43cnx8

May 9, 2021 · 50 followers View post →
Roland Dunbrack
@RolandDunbrack · X

@cheprofessor @MLevitt_NP2013 Nature also published a BS paper on homeopathy and "water memory" which was never retracted. Not likely they will retract this one unless there is fraud. But they every right (and perhaps obligation) to publish critiques of the paper. https://t.co/nR6OXa3WYm

Mar 13, 2021 · 4,213 followers View post →
Gregorio Segovia
@segoviag969 · X

@nlopeztrujillo Solo recordarte que Nature publicó hace años este articulo que "demostraba" la memoria del agua, el supuesto fundamento de la homeopatía. https://t.co/egf42NjDFz

Dec 9, 2020 · 4,213 followers View post →
Madeline - La chère poire
@LaCherePoire · X

@Aentwan @TroncheBiais D'ailleurs, tellement cachée qu'elle est publiquement accessible => https://t.co/JBdek4fYnS

Sep 29, 2019 · 1,139 followers View post →