Proc Natl Acad Sci U S A October 2014 PMID 25313065

Sulforaphane treatment of autism spectrum disorder (ASD).

Kanwaljit Singh, Susan L Connors, Eric A Macklin, Kirby D Smith, Jed W Fahey, Paul Talalay, Andrew W Zimmerman

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238

Peak: 20 in Nov 2024

across 6 sources since Apr 2020

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What people are saying

The discussions demonstrate a generally supportive attitude toward the research, with many posts referencing scientific studies and mechanisms such as anti-inflammatory effects and blood-brain barrier crossing, exemplified in phrases like 'neuroprotective pathways activate' and references to specific dosage studies. Additionally, personal anecdotes and curiosity about clinical significance highlight active engagement and interest.

AgreementModerate agreement

Most discussions recognize the potential benefits of sulforaphane for ASD, supporting its positive effects documented in studies.

InterestHigh interest

Posts show high curiosity, referencing related research, proposed mechanisms, and personal or clinical experiences.

EngagementModerate engagement

Users actively discuss the biological pathways, cite specific research papers, and consider the social implications, indicating thoughtful engagement.

ImpactModerate impact

While some acknowledge preliminary results, the overall tone suggests the discussions could influence opinions on dietary supplements and treatments for ASD.

Abstract in brief

The study investigates the effects of sulforaphane, a compound derived from broccoli sprouts, on young men with moderate to severe Autism Spectrum Disorder (ASD), finding significant behavioral improvements after 18 weeks of treatment.
Participants receiving sulforaphane showed notable reductions in behaviors related to ASD, such as social interaction and verbal communication issues, while placebo groups showed minimal change.
After stopping treatment, behavioral scores gradually returned to baseline levels, and sulforaphane was chosen for its low toxicity and potential to reverse biological abnormalities associated with ASD, like oxidative stress and neuroinflammation.]

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All mentions

Benefits of Sulforaphane from Broccoli for Autism and ADHD Improvement

Oxidative stress and inflammation are linked to neurodevelopmental disorders like Autism and ADHD. Sulforaphane, a potent antioxidant found in broccoli, has been shown to reduce inflammation and improve behavioral…

Puzzle Kids · Jun 19, 2024 2,157 views

How to Approach Suspected Autism in Your Child

If you suspect your child has autism, this video offers insights into the challenges faced by parents and the early steps to take. It covers understanding Autism Spectrum Disorder and explores the potential of…

Sacando punta a la vida · Jun 24, 2025 35 views

David

@mitter81 · X

@DebraDeniston and again, oddly, it took me back to presentations on the spectrum, and detox of pollutants, nothing in the detox mitigation is changing my genetic makeup, but it changes all the symptoms https://t.co/cRgIDh5HM5

Sep 10, 2025 · 1,393 followers View post →

Hediye

@Hediyeerdemir · X

RT @drkaanyl: 4) Sulforaphane = beyin güçlendirici Kan-beyin bariyerini geçer ve: • Beyindeki iltihabı azaltır • Nöroprotektif yolları akti…

May 4, 2025 · 12 shares · 485 followers View post →

A.Erdoğan

@Edebi_Komando · X

RT @drkaanyl: 4) Sulforaphane = beyin güçlendirici Kan-beyin bariyerini geçer ve: • Beyindeki iltihabı azaltır • Nöroprotektif yolları akti…

May 4, 2025 · 12 shares · 642 followers View post →

cfa

@fatihalptekin78 · X

RT @drkaanyl: 4) Sulforaphane = beyin güçlendirici Kan-beyin bariyerini geçer ve: • Beyindeki iltihabı azaltır • Nöroprotektif yolları akti…

May 4, 2025 · 12 shares · 1,890 followers View post →

deniz pınar

@PnarOcean2006 · X

RT @drkaanyl: 4) Sulforaphane = beyin güçlendirici Kan-beyin bariyerini geçer ve: • Beyindeki iltihabı azaltır • Nöroprotektif yolları akti…

May 4, 2025 · 12 shares · 134 followers View post →

zeyna aydın

@ZeynaAydin · X

RT @drkaanyl: 4) Sulforaphane = beyin güçlendirici Kan-beyin bariyerini geçer ve: • Beyindeki iltihabı azaltır • Nöroprotektif yolları akti…

May 4, 2025 · 12 shares · 1,066 followers View post →

Ahmet Arapoğlu

@arapamed · X

RT @drkaanyl: 4) Sulforaphane = beyin güçlendirici Kan-beyin bariyerini geçer ve: • Beyindeki iltihabı azaltır • Nöroprotektif yolları akti…

May 4, 2025 · 12 shares · 82 followers View post →

Zekeriya. Kalkan

@smmm_zkalkan · X

RT @drkaanyl: 4) Sulforaphane = beyin güçlendirici Kan-beyin bariyerini geçer ve: • Beyindeki iltihabı azaltır • Nöroprotektif yolları akti…

May 3, 2025 · 12 shares · 3,828 followers View post →

Tevfik Bilgiç

@kuran_yeter46 · X

RT @drkaanyl: 4) Sulforaphane = beyin güçlendirici Kan-beyin bariyerini geçer ve: • Beyindeki iltihabı azaltır • Nöroprotektif yolları akti…

May 3, 2025 · 12 shares · 2,403 followers View post →

İbrahim Acar ❗️A TAKIMI❗️

@ibrahimacar5334 · X

RT @drkaanyl: 4) Sulforaphane = beyin güçlendirici Kan-beyin bariyerini geçer ve: • Beyindeki iltihabı azaltır • Nöroprotektif yolları akti…

May 3, 2025 · 12 shares · 5,035 followers View post →

GÖKAY YILDIRIM

@gky_yildirim · X

RT @drkaanyl: 4) Sulforaphane = beyin güçlendirici Kan-beyin bariyerini geçer ve: • Beyindeki iltihabı azaltır • Nöroprotektif yolları akti…

May 3, 2025 · 12 shares · 3,158 followers View post →

Prof. Dr. Hasan Ünal

@hasanunal1920 · X

RT @drkaanyl: 4) Sulforaphane = beyin güçlendirici Kan-beyin bariyerini geçer ve: • Beyindeki iltihabı azaltır • Nöroprotektif yolları akti…

May 3, 2025 · 12 shares · 80,178 followers View post →

nuray candoğan

@nuraycandogan20 · X

RT @drkaanyl: 4) Sulforaphane = beyin güçlendirici Kan-beyin bariyerini geçer ve: • Beyindeki iltihabı azaltır • Nöroprotektif yolları akti…

May 3, 2025 · 12 shares · 1,441 followers View post →

Prof. Dr. Kaan Yılancıoğlu

@drkaanyl · X

May 3, 2025 · 127 likes · 12 shares · 207,497 followers View post →

てでぃ。

@uyodo_shujin · X

RT @uranus_2: 男性の自閉症の症状はスルフォラファンで改善できる。社会的交流や異常行動、言語コミュニケーションが改善する(CGI-I)。Sulforaphane treatment of autism spectrum disorder (ASD) http://t…

Mar 28, 2025 · 1 share · 947 followers View post →

hunter klapperich

@originator39 · X

RT @originator39: Sulforaphane Treatment of Autism Spectrum Disorder (ASD) - PubMed https://t.co/CoTmu9mmY7

Mar 28, 2025 · 1 share · 1,953 followers View post →

norma

@normaver_1 · X

一時期すこしバズったスルフォラファンのASDへの効果についてちょっと検証しようと諸々調べています。 oral doses sulforaphane of (50–150 µmol) for 18 wk,、つまり約 8.86–26.59 mg/日 x 18週間で有意な結果が得られた、というのが趣旨 https://t.co/9ES2Zf9Jae

Jan 20, 2025 · 1 like · 41 followers View post →

Albert Gasull

@AlbertGasull · X

@MOrdinary1982 @bryan_johnson Concentration of sulphorephane in broccoli (not broccoli sprouts) is pretty low. There are few studies on it. Low toxicity and significant social interactions results. https://t.co/KEf97heYZd

Dec 10, 2024 · 496 followers View post →

seymauzun

@seymauzun17 · X

RT @Ferhatarslandr: Makale nerde hoca diye şimdi soranlar olur. https://t.co/bmwyKRvyDW

Nov 17, 2024 · 22 shares · 23 followers View post →

bguvenyavuz

@guveny888 · X

RT @Ferhatarslandr: Makale nerde hoca diye şimdi soranlar olur. https://t.co/bmwyKRvyDW

Nov 16, 2024 · 22 shares · 199 followers View post →

Fatih Turkay

@FatihTurkay3 · X

https://t.co/jF9SlWtz9H

Nov 10, 2024 · 1 like · 21 followers View post →

Hello World !

@RudolphisHere17 · X

RT @Ferhatarslandr: Makale nerde hoca diye şimdi soranlar olur. https://t.co/bmwyKRvyDW

Nov 10, 2024 · 22 shares · 283 followers View post →

KIRCAALİ

@T_C_NY · X

RT @Ferhatarslandr: Makale nerde hoca diye şimdi soranlar olur. https://t.co/bmwyKRvyDW

Nov 10, 2024 · 22 shares · 1,544 followers View post →

adem cukadar

@adem_cukadar · X

RT @Ferhatarslandr: Makale nerde hoca diye şimdi soranlar olur. https://t.co/bmwyKRvyDW

Nov 10, 2024 · 22 shares · 583 followers View post →

rska09

@raskamu · X

RT @Ferhatarslandr: Makale nerde hoca diye şimdi soranlar olur. https://t.co/bmwyKRvyDW

Nov 10, 2024 · 22 shares · 1,166 followers View post →

Dilek Duygu

@Dilekduygu7 · X

RT @Ferhatarslandr: Makale nerde hoca diye şimdi soranlar olur. https://t.co/bmwyKRvyDW

Nov 10, 2024 · 22 shares · 541 followers View post →

farkettim

@Fikorettin · X

RT @Ferhatarslandr: Makale nerde hoca diye şimdi soranlar olur. https://t.co/bmwyKRvyDW

Nov 9, 2024 · 22 shares · 289 followers View post →

Mustafa YILDIRIM

@mustafa1279 · X

RT @Ferhatarslandr: Makale nerde hoca diye şimdi soranlar olur. https://t.co/bmwyKRvyDW

Nov 9, 2024 · 22 shares · 660 followers View post →

hülya ezer

@flzzr · X

RT @Ferhatarslandr: Makale nerde hoca diye şimdi soranlar olur. https://t.co/bmwyKRvyDW

Nov 9, 2024 · 22 shares · 425 followers View post →

Tamer KÂMİLOĞLU

@tamerkamiloglu · X

RT @Ferhatarslandr: Makale nerde hoca diye şimdi soranlar olur. https://t.co/bmwyKRvyDW

Nov 9, 2024 · 22 shares · 822 followers View post →

ferhat acukcu( فرحت)

@ferhatacukcu · X

RT @Ferhatarslandr: Makale nerde hoca diye şimdi soranlar olur. https://t.co/bmwyKRvyDW

Nov 9, 2024 · 22 shares · 206 followers View post →

Mehmet Sait

@msbalci1_sait · X

RT @Ferhatarslandr: Makale nerde hoca diye şimdi soranlar olur. https://t.co/bmwyKRvyDW

Nov 9, 2024 · 22 shares · 2,720 followers View post →

HASAN

@HASAN58281935 · X

RT @Ferhatarslandr: Makale nerde hoca diye şimdi soranlar olur. https://t.co/bmwyKRvyDW

Nov 9, 2024 · 22 shares · 65 followers View post →

Ahmet ÖZ

@ahmetoz_ · X

RT @Ferhatarslandr: Makale nerde hoca diye şimdi soranlar olur. https://t.co/bmwyKRvyDW

Nov 9, 2024 · 22 shares · 205 followers View post →

BUYRUĞUM

@2Sahsim · X

RT @Ferhatarslandr: Makale nerde hoca diye şimdi soranlar olur. https://t.co/bmwyKRvyDW

Nov 9, 2024 · 22 shares · 2,593 followers View post →

penbesabrina

@sabrinapenbe · X

RT @Ferhatarslandr: Makale nerde hoca diye şimdi soranlar olur. https://t.co/bmwyKRvyDW

Nov 9, 2024 · 22 shares · 206 followers View post →

Adnan Güneş

@apgunes64 · X

RT @Ferhatarslandr: Makale nerde hoca diye şimdi soranlar olur. https://t.co/bmwyKRvyDW

Nov 9, 2024 · 22 shares · 171 followers View post →

Doç. Dr. Ferhat Arslan

@Ferhatarslandr · X

Makale nerde hoca diye şimdi soranlar olur. https://t.co/bmwyKRvyDW

Nov 9, 2024 · 157 likes · 22 shares · 228,853 followers View post →

John Nez

@John_Nez_Artist · X

@alisonkatebr Suphurophane has been shown to help improve autism symptoms in some people - it's made from broccoli sprouts basically - https://t.co/SvrbW5LMV5

Jul 22, 2024 · 2,206 followers View post →

KLee #MAGA

@KLee22715053 · X

@D00MMittens @holdfast2021 @VigilantFox Sulforaphane. Hears a link about it. https://t.co/kJnrsaGREC

May 30, 2024 · 1 like · 2,476 followers View post →

John Nez

@John_Nez_Artist · X

@providenceluvr https://t.co/X6hzLZ0zdd has lots of nutritional health tips, where he bases cures on food, instead of pharmaceuticals. I didn’t know things like asparagus sprouts can help with autism. Sulforaphane treatment of autism spectrum disorder (ASD) | PNAS https://t.co/SvrbW5LMV5

Apr 14, 2024 · 2,206 followers View post →

anaya3d

@anaya3d · X

Nov 16, 2023 · 2 likes · 162 followers View post →

JeffWill

@J_Real3 · X

https://t.co/uP6kVBP5wd

Oct 14, 2023 · 5,066 followers View post →

@lovetruthmatter

@lovetruthmatter · X

RT @and_kell: @LoriShemek There has been some research into using broccoli sprouts with autistic patients. My son's func med Dr. recommende…

Oct 11, 2023 · 3 shares · 349 followers View post →

kldguitar@hotmail.com

@KLDguitaramp · X

RT @and_kell: @LoriShemek There has been some research into using broccoli sprouts with autistic patients. My son's func med Dr. recommende…

Oct 9, 2023 · 3 shares · 2,483 followers View post →

Andrea

@and_kell · X

Oct 9, 2023 · 12 likes · 3 shares · 7,255 followers View post →

إكـرام

@88Iqram · X

https://t.co/CUH4NwbpRl - في تجربة تلقى شباب (أعمارهم بين 13 و 27 عامًا) لديهم ASD معتدل إلى شديد مادة السلفورافان الكيميائية النباتية (ن = 29) أو دواء وهمي (ن = 15). - لوحظ في المجموعة التي اخذت السلفورافان تحسن في التفاعل الاجتماعي والسلوك غير الطبيعي والتواصل اللفظي.

Jun 21, 2023 · 1 like · 257 followers View post →

filho do Daft, sobrinho do Punk

@thikski · X

@mechazord_ achei um estudo que fala um pouco sobre alguns testes clínicos e aparentemente pessoas que tomaram sulforano (um dos fitoativos que compõe o brocophanus) mostraram melhora em questões de interação social, comunicação e outras coisas https://t.co/yNB1Xcq2Ry

Jun 6, 2023 · 673 followers View post →

Jerod

@blacksectional · X

This seems too good to be true: An effective intervention for autism that is cheap, not copywritten, legal in the US? https://t.co/UlL5IVtgva

Apr 2, 2023 · 2,323 followers View post →

spiegels ASS

@aandewand · X

@icandothisshiit @Miesli2 Het artikel op PNAS heeft het dan weer over 50–150 µmol - net als de bijgesloten tweet. https://t.co/Ot3CQtpibZ

Mar 6, 2023 · 108 followers View post →

Henrik Bentzen

@hben61jul · X

Sulforaphane treatment of autism spectrum disorder (ASD) https://t.co/CnAlVYFOkS

Sep 28, 2022 · 2,365 followers View post →

Terra cremada

@terra_cremada · X

ℹ️Tratamiento con sulforafano del trastorno del espectro autista (TEA https://t.co/ep2teEbr8u

Sep 19, 2022 · 3 likes · 43,454 followers View post →

Mehmet Arif Mirasoğlu

@Mehmet_1326 · X

https://t.co/Jos3X4IY8f

Jul 31, 2022 · 914 followers View post →

Usagi

@usagimusic · X

Sulforaphane treatment of autism spectrum disorder (ASD) https://t.co/80HTEH1lDm

May 20, 2022 · 257 followers View post →

Make A Stand 4 Autism

@MakeAStandOrg · X

Well, Johns Hopkins might have something to say about that. Not sure your anecdotal report is going to hold up to their placebo-controlled, double-blind research, but thanks for playing. https://t.co/agMFmDYI5c https://t.co/oP2qFkI06w

May 17, 2022 · 1,139 followers View post →

tune

@keisuke4713 · X

自閉症スペクトラム障害(ASD)SFN治療https://t.co/AEhUQnggcb プラセボ対照無作為化二重盲検臨床試験 ASD若い男性29人にSFN毎日18週経口投与プラセボ15人と比べ行動が大幅(可逆的)改善毒性無視できるSFN選択は、酸化ストレス、炎症、DNA損傷から好気性細胞保護する遺伝子アップレギュレートするため https://t.co/fuYZCmzJ08

Mar 7, 2022 · 3,741 followers View post →

Shinya Satake@大宮区@過眠症圏@夜型クロノタイプ@早朝ビル清掃@Beatlesコピバン

@uPkKLnbJUWCCPBL · X

Sulforaphane treatment of autism spectrum disorder (ASD) https://t.co/xAiCjN2vMR スルフォラファンはうつ予防、肥満を抑制、インスリン抵抗性も改善、ASDの症状そのものを改善。抗酸化作用。 HbA1cが正常値になって、糖尿病予防目的で内服するには私にはピッタリです。

Sep 26, 2021 · 8,298 followers View post →

Mario

@Beteljuice · X

https://t.co/BVFO3ii5m8

Oct 29, 2020 · 4 likes · 1 share · 1,993 followers View post →

hunter klapperich

@originator39 · X

Sulforaphane Treatment of Autism Spectrum Disorder (ASD) - PubMed https://t.co/CoTmu9mmY7

Apr 19, 2020 · 1 share · 1,953 followers View post →

Sulforaphane treatment of autism spectrum disorder (ASD).

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Benefits of Sulforaphane from Broccoli for Autism and ADHD Improvement

How to Approach Suspected Autism in Your Child