Proc Natl Acad Sci U S A January 2015 PMID 25453080

Hominids adapted to metabolize ethanol long before human-directed fermentation.

Matthew A Carrigan, Oleg Uryasev, Carole B Frye, Blair L Eckman, Candace R Myers, Thomas D Hurley, Steven A Benner

Mentions

64
Peak: 8 in Feb 2023
across 7 sources since Jul 2016

Extended reach

109,542
potential audience

Total likes

1,789

Video views

45,213

Mentions per month

Jul 2016 – Nov 2025

Where it's discussed

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AI synopsis

What people are saying

Overall, discussions show strong agreement with the research, as evidenced by references to genetic mutations and evolutionary adaptations, such as 'the ability to metabolize alcohol 20x' and mentions of 'long before fermentation.' The tone reflects curiosity and respect for scientific findings, with phrases like 'adapted long before' and 'ground living, eating overripe fruit,' emphasizing the importance and impact of this discovery on our understanding of human evolution.

AgreementStrong agreement

Most discussions reflect strong agreement with the article's assertion that early hominids adapted to metabolize ethanol long before human fermentation practices.

InterestHigh interest

Posts demonstrate high interest by referencing detailed genetic studies and evolutionary implications, indicating deep engagement with the topic.

EngagementModerate engagement

While many participants cite scientific findings and historical context, some comments are brief or dismissive, leading to moderate engagement overall.

ImpactHigh impact

The discussions highlight significant scientific and evolutionary implications, with some posts suggesting this research could reshape understanding of human ancestry and dietary adaptations.

Top posts

Most liked on X and Bluesky
Doug Jones
@logarithmic_h · X

10 Mya. Drunken monkey: point mutation boosts human/chimp/gorilla ancestor’s ability to metabolize alcohol 20x. Adaptation to ground living, eating boozy overripe fallen fruit? https://t.co/Xd9FPhsxRW

May 8, 2024 · 5 likes · 1 share · 928 followers View post →
Cat Hobaiter
@NakedPrimate · X

10yrs ago Carrigan & colleagues showed that only African apes (but not other primates, including orangutans) have a single mutation in their ADH4 gene that makes them 40x (!) more efficient at metabolizing alcohol https://t.co/sRbhLmZoYX 2/15 https://t.co/xxL4HVE2tz

Aug 1, 2025 · 4 likes · 4,783 followers View post →
ThePlantLab
@ThePlantLab · X

Hominids adapted to metabolize ethanol long before human-directed fermentation | PNAS https://t.co/TTmVXTOvcP

Jul 24, 2023 · 4 likes · 1,602 followers View post →
Ed Hagen
@edhagen.net · Bluesky

You're correct: Hominids adapted to metabolize ethanol long before human-directed fermentation: www.pnas.org/doi/10.1073/...

Jan 6, 2024 · 4 likes · 1 share View post →
Ananda Sangeetam
@anuswaram · X

దారి తీయడం వల్లే బీయర్ బెల్లీ లు గట్రా వస్తాయి. https://t.co/kb5mPhUk57

Apr 20, 2022 · 3 likes · 4,566 followers View post →
Mingye Wang 4.0.1(已九价)
@Artoria2e5 · X

@silsrc 人类是人类之前就已经特别能代谢乙醇了 https://t.co/LdrgdGi3rM

Apr 15, 2025 · 3 likes · 2,131 followers View post →

All mentions

rasNobu
@rasNobu · X

Human evolution and alcohol. Why can't Homo sapiens stop drinking? The d... https://t.co/ACjj8jW0OZ

Nov 29, 2025 · 4,667 followers View post →
東京4130
@rockdacypher · X

https://t.co/2LFlKu6JaX

Nov 29, 2025 · 1 like · 12,680 followers View post →
そのまんまな親父
@LU6nNjJUcJae4gV · X

@yasuhi10 https://t.co/QgP9iYI9nW

Nov 20, 2025 · 224 followers View post →
なべ
@Kagaku_e · X

https://t.co/TqU8HZc786

Nov 18, 2025 · 1 like · 92 followers View post →
Cat Hobaiter
@NakedPrimate · X

10yrs ago Carrigan & colleagues showed that only African apes (but not other primates, including orangutans) have a single mutation in their ADH4 gene that makes them 40x (!) more efficient at metabolizing alcohol https://t.co/sRbhLmZoYX 2/15 https://t.co/xxL4HVE2tz

Aug 1, 2025 · 4 likes · 4,783 followers View post →
Mingye Wang 4.0.1(已九价)
@Artoria2e5 · X

@silsrc 人类是人类之前就已经特别能代谢乙醇了 https://t.co/LdrgdGi3rM

Apr 15, 2025 · 3 likes · 2,131 followers View post →
bruce
@bruce99340413 · X

RT @logarithmic_h: 10 Mya. Drunken monkey: point mutation boosts human/chimp/gorilla ancestor’s ability to metabolize alcohol 20x. Adaptati…

May 9, 2024 · 1 share · 204 followers View post →
Doug Jones
@logarithmic_h · X

10 Mya. Drunken monkey: point mutation boosts human/chimp/gorilla ancestor’s ability to metabolize alcohol 20x. Adaptation to ground living, eating boozy overripe fallen fruit? https://t.co/Xd9FPhsxRW

May 8, 2024 · 5 likes · 1 share · 928 followers View post →
Ed Hagen
@edhagen.net · Bluesky

You're correct: Hominids adapted to metabolize ethanol long before human-directed fermentation: www.pnas.org/doi/10.1073/...

Jan 6, 2024 · 4 likes · 1 share View post →
Ananda Sangeetam
@anuswaram · X

https://t.co/kBID3Hck5S https://t.co/4FwWkm7t9e

Dec 31, 2023 · 1 like · 4,566 followers View post →
ThePlantLab
@ThePlantLab · X

Hominids adapted to metabolize ethanol long before human-directed fermentation | PNAS https://t.co/TTmVXTOvcP

Jul 24, 2023 · 4 likes · 1,602 followers View post →
Amer
@AmerNaik · X

Hominids adapted to metabolize ethanol long before human-directed fermentation | PNAS Fire peer review about drank https://t.co/VorhmlcGiX

Jun 21, 2023 · 1,678 followers View post →
Doug Jones
@logarithmic_h · X

10 Mya. Drunken monkey: point mutation boosts human/chimp/gorilla ancestor’s ability to metabolize alcohol 20x. Adaptation to ground living, eating boozy overripe fallen fruit? https://t.co/Xd9FPhsxRW

May 9, 2023 · 2 likes · 928 followers View post →
LinnaeaVineyards
@LinnaeaVineyard · X

This transition implies that the genomes of modern human, chimpanzee, and gorilla began adapting at least 10 million y ago to dietary ethanol present in fermenting fruit https://t.co/3dOxShqeHm #wine

Apr 7, 2023 · 518 followers View post →
Stefano Berto, PhD
@StefanoBerto83 · X

@CristinaDragani @Invetriata + evoluzione dell'abilità di metabolizzare etanolo e l'adattamento https://t.co/Qesb5qSaVk E "epidemiological studies suggest a reduction in cardiovascular risk and overall mortality at low levels of ethanol consumption relative either to abstinence or to higher levels"

Jan 22, 2023 · 1 like · 7,878 followers View post →
Kelly A. Hogan Ph.D.
@Loose_Lab_Rat · X

Hominids adapted to metabolize ethanol long before human-directed fermentation https://t.co/f7zeBJxqEz

Jan 4, 2023 · 2,234 followers View post →
David A. Oliver
@DavidAOliverJr · X

@Ruediger_Krech @WHO https://t.co/6DkwcJGUqV

Jan 4, 2023 · 1 like · 935 followers View post →
Not/Relief
@NoesRelief · X

@3Wxrb2K Esta bien tener una opinion impopular, pero decir que la wea es así sin si quiera buscar fuentes confiables es ya o buscar atención o darselas de edgelord https://t.co/JQKgzaOuHm

Dec 6, 2022 · 124 followers View post →
₿itcoin & Beer
@BeerBitcoin · X

RT @BeerBitcoin: “Hominids adapted to metabolize ethanol long before human-directed fermentation” - Matthew A Carrigan et al. Proc Natl Aca…

Sep 8, 2022 · 2 shares · 1,029 followers View post →
Janis Liepins
@j_liepins · X

@klavsse Paldies par norādi, būs jāizlasa oriģinālais avots https://t.co/gE1Z9DBFbY

Jun 1, 2022 · 481 followers View post →
Doug Jones
@logarithmic_h · X

10 Mya. Drunken monkey: point mutation boosts human/chimp/gorilla ancestor’s ability to metabolize alcohol 20x. Adaptation to ground living, eating boozy overripe fallen fruit? https://t.co/Xd9FPhJATW

May 9, 2022 · 928 followers View post →
Ananda Sangeetam
@anuswaram · X

దారి తీయడం వల్లే బీయర్ బెల్లీ లు గట్రా వస్తాయి. https://t.co/kb5mPhUk57

Apr 20, 2022 · 3 likes · 4,566 followers View post →
bitcoin brunch network
@brunchofbitcoin · X

RT @BeerBitcoin: “Hominids adapted to metabolize ethanol long before human-directed fermentation” - Matthew A Carrigan et al. Proc Natl Aca…

Dec 27, 2021 · 2 shares · 537 followers View post →
Science Daily
@philipbethge · X

RT @topechidna: Hominids adapted to metabolize ethanol long before human-directed fermentation https://t.co/xTwkbPFddM

Dec 26, 2021 · 2 shares · 1,487 followers View post →
A Parody Of The Former Parody Of Myself
@PeteLawler · X

RT @topechidna: Hominids adapted to metabolize ethanol long before human-directed fermentation https://t.co/xTwkbPFddM

Dec 25, 2021 · 2 shares · 303 followers View post →
Stewart Nicol
@topechidna · X

Hominids adapted to metabolize ethanol long before human-directed fermentation https://t.co/xTwkbPFddM

Dec 25, 2021 · 1 like · 2 shares · 391 followers View post →
₿itcoin & Beer
@BeerBitcoin · X

“Hominids adapted to metabolize ethanol long before human-directed fermentation” - Matthew A Carrigan et al. Proc Natl Acad Sci U S A. 2015 [https://t.co/x2HPHN8FtH] https://t.co/GyqzLF0vC2 https://t.co/hem2QQWuuX

Dec 16, 2021 · 3 likes · 2 shares · 1,029 followers View post →
Wab Mester
@wabmester · X

@NanciGuestRDPhD @ScepticalDoctor Alcohol didn't exist? This may convert you to paleo: https://t.co/1ZBzTl1HbC

Jun 27, 2021 · 1 like · 276 followers View post →
Karwat Zenon (still 15)
@zenjk0 · X

RT @ElenaHaskins: 2015: Hominids adapted to metabolize ethanol long before human-directed fermentation https://t.co/PrdcCg7lTS

Aug 4, 2020 · 1 share · 3,312 followers View post →
Elena Haskins, Authentic American
@ElenaHaskins · X

2015: Hominids adapted to metabolize ethanol long before human-directed fermentation https://t.co/PrdcCg7lTS

Aug 4, 2020 · 1 share · 3,464 followers View post →
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