The discussions display genuine curiosity, with posts explaining the hypothalamus's role in circadian rhythms and hormonal regulation, using words like 'crucial,' 'control center,' and 'regulates,' which highlight its importance; detailed references to research and medical implications show moderate engagement and a recognition of its broad impact.
AgreementModerate agreement
Most discussions acknowledge the importance and multifaceted functions of the hypothalamus, supporting the article's depiction of it as a key regulatory brain region.
InterestHigh interest
The posts show high curiosity and fascination with the hypothalamus's roles in sleep, hormones, and behavior, indicating strong engagement with the topic.
EngagementModerate engagement
Several comments go beyond surface comments, referencing detailed mechanisms, research studies, and potential medical interventions, suggesting moderate depth of discussion.
ImpactModerate impact
While many recognize the hypothalamus's significance in health and disease, the overall sense is that these discussions contribute to ongoing scientific understanding rather than immediate real-world change.
Abstract in brief
The hypothalamus is a small but crucial part of the brain located below the thalamus, and it plays a key role in maintaining the body's internal balance, or homeostasis.
It controls various bodily functions such as hunger, thirst, temperature regulation, sleep, and emotional responses by releasing hormones that influence other glands.
The hypothalamus works closely with the pituitary gland to regulate growth, metabolism, and stress responses, making it essential for overall health and stability.]
Núcleos del HIPOTÁLAMO:
Current Biology 2014; DOI: https://t.co/zXTmMSmC35 https://t.co/WkiHRTaepG
Oct 15, 2021 · 159 likes · 32 shares · 71,595 followersView post →
PE
☣️ Pleb Kruse = BTC foundationalist in exile
@DrJackKruse · X
Tech abuse facilitates it. nnEMF controls the hypothalamus. Stay up with the tribe bro. @ze_rusty just posted about it not too long ago. https://t.co/ncS9hiWGKO https://t.co/onLULfjzOU
Nov 14, 2025 · 108 likes · 26 shares · 125,965 followersView post →
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Tofman
@tofmannn · X
@instablog9ja Very thoughtful question.
Whether a woman in a coma continues to menstruate depends on the integrity of her neuroendocrine system.
If the hypothalamus and pituitary gland remain functional, normal hormonal cycles, and thus menstruation, can persist.
However, severe brain
Nov 13, 2025 · 50 likes · 2 shares · 1,153 followersView post →
AD
Amelia Douglass
@amdouglass.bsky.social · Bluesky
I'm over the moon and incredibly grateful to receive an @erc.europa.eu Starting Grant to support our work on the control of behavior and bodily physiology by the hypothalamus @istaresearch.bsky.social. This means we are hiring, so please get in touch if interested!
“Scientists identify virus causing fatigue in ME“
“We’ve found defective immunity, evidence of persistent viral infection, ABNORMAL MITOCHONDRIA and the hypothalamus not functioning!” P. Behan et al Glasgow 1990 (!!!) #MyalgicE #MECFS #PwME #Mitochondria #PostViralSequelae
The hypothalamus is a complex brain region vital for maintaining homeostasis by integrating sensory inputs. Recent technological advances like single-cell RNA sequencing are enhancing our understanding of its…
Learn how addiction develops through the brain's reward system and the factors influencing it, including risk and the inability to feel pleasure. Explore prevention and treatment options, including psychotherapy and the…
The hypothalamus and pituitary gland work together to produce and release a number of hormones that are critically important for a long list of functions in the body. The hypothalamus, located below the thalamus…
The hypothalamus is a small but vital brain structure that maintains the body's internal balance by regulating hunger, thirst, temperature, sleep, and emotions through hormonal control, working closely with the…
RT @litwisar: Haha nope. People wake up after sleep due to the circadian rhythm, an internal ~24-hour biological clock regulated by the sup…
Nov 15, 2025 · 5 shares · 49,272 followersView post →
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Nickie
@i_amnickie · X
RT @litwisar: Haha nope. People wake up after sleep due to the circadian rhythm, an internal ~24-hour biological clock regulated by the sup…
Nov 15, 2025 · 5 shares · 2,704 followersView post →
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Pub_loo
@george3048 · X
RT @litwisar: Haha nope. People wake up after sleep due to the circadian rhythm, an internal ~24-hour biological clock regulated by the sup…
Nov 15, 2025 · 5 shares · 1,730 followersView post →
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Litwisar
@litwisar · X
Haha nope. People wake up after sleep due to the circadian rhythm, an internal ~24-hour biological clock regulated by the suprachiasmatic nucleus (SCN) in the hypothalamus. https://t.co/F3Qpv76TXH
Nov 15, 2025 · 10 likes · 5 shares · 2,088 followersView post →
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NEET
@firelightsaga · X
RT @DrJackKruse: Tech abuse facilitates it. nnEMF controls the hypothalamus. Stay up with the tribe bro. @ze_rusty just posted about it n…
Nov 14, 2025 · 26 shares · 21 followersView post →
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Grok
@grok · X
@EquityGrantNet Sexual circuits in the hypothalamus and amygdala develop prenatally under hormonal influence, enabling behavioral responses before extensive pruning, as replicated in animal models and human neuroimaging. Adolescent experience shapes refinement through plasticity, yet Dunedin and
RT @DrJackKruse: Tech abuse facilitates it. nnEMF controls the hypothalamus. Stay up with the tribe bro. @ze_rusty just posted about it n…
Nov 14, 2025 · 26 shares · 64 followersView post →
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Danielle Dyer
@danielle4657 · X
it follows but it's just Lt. Caine + Elon Musk fucking with you for Big Hoss republicans
imagine sending me out there to die
knowing I had a some kind
tbh it very well might have been some kind of tumor related to the hypothalamus, pituitary gland vs. an ethmoid, sphenoid
@FloridamanBrett @james_jabroni @jaxwilldonicely @mushycrouton Gender identity is actually a product of self perception within the BNST of the hypothalamus and prefrontal cortex, in relation to stimuli applied having to do with the identity.
RT @DrJackKruse: Tech abuse facilitates it. nnEMF controls the hypothalamus. Stay up with the tribe bro. @ze_rusty just posted about it n…
Nov 14, 2025 · 26 shares · 2,785 followersView post →
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Joey C
@BuildFT · X
RT @DrJackKruse: Tech abuse facilitates it. nnEMF controls the hypothalamus. Stay up with the tribe bro. @ze_rusty just posted about it n…
Nov 14, 2025 · 26 shares · 92 followersView post →
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TexFlyer
@FlyerTex · X
RT @DrJackKruse: Tech abuse facilitates it. nnEMF controls the hypothalamus. Stay up with the tribe bro. @ze_rusty just posted about it n…
Nov 14, 2025 · 26 shares · 1,026 followersView post →
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Lonni Clarke
@londerosa · X
RT @DrJackKruse: Tech abuse facilitates it. nnEMF controls the hypothalamus. Stay up with the tribe bro. @ze_rusty just posted about it n…
Nov 14, 2025 · 26 shares · 3,366 followersView post →
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HaunterCreative
@HaunterCreative · X
@Melissa14697526 @PureAnime1 @mushycrouton @RayAlexWilliams Gender is observed via brain scans and where they light up, having to do with the BNST of the hypothalamus and prefrontal cortex. Now about that bi-erasure you've got going on...
RT @DrJackKruse: Tech abuse facilitates it. nnEMF controls the hypothalamus. Stay up with the tribe bro. @ze_rusty just posted about it n…
Nov 14, 2025 · 26 shares · 481 followersView post →
IC
il curioso
@borncurious369 · X
RT @DrJackKruse: Tech abuse facilitates it. nnEMF controls the hypothalamus. Stay up with the tribe bro. @ze_rusty just posted about it n…
Nov 14, 2025 · 26 shares · 700 followersView post →
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Lizzy Adejoh
@lizzy_adej74157 · X
@that_fine_gen Yes, usually, unless the hypothalamus is affected by a brain injury, which can throw off the menstrual cycle.
Nov 14, 2025 · 1 like · 1,206 followersView post →
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dearsand
@TrendTrailll · X
@that_fine_gen Yes, they usually do unless a brain injury affects the hypothalamus, which can disrupt the menstrual cycle.
Nov 14, 2025 · 3 likes · 7,275 followersView post →
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Arielo
@arielsaul · X
RT @DrJackKruse: Tech abuse facilitates it. nnEMF controls the hypothalamus. Stay up with the tribe bro. @ze_rusty just posted about it n…
Nov 14, 2025 · 26 shares · 920 followersView post →
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PC ⛓
@PC65049955 · X
RT @DrJackKruse: Tech abuse facilitates it. nnEMF controls the hypothalamus. Stay up with the tribe bro. @ze_rusty just posted about it n…
Nov 14, 2025 · 26 shares · 1,458 followersView post →
FB
Farren Brown
@coachwesnoski · X
DSIP
DSIP regulates sleep/wake cycles at the hypothalamus.
It reduces nighttime adrenaline and stabilizes cortisol rhythm.
100–300 mcg subQ 30–60 minutes pre-bed.
RT @DrJackKruse: Tech abuse facilitates it. nnEMF controls the hypothalamus. Stay up with the tribe bro. @ze_rusty just posted about it n…
Nov 14, 2025 · 26 shares · 540 followersView post →
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Jonathan
@Hair_Artiste · X
RT @DrJackKruse: Tech abuse facilitates it. nnEMF controls the hypothalamus. Stay up with the tribe bro. @ze_rusty just posted about it n…
Nov 14, 2025 · 26 shares · 786 followersView post →
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DiegoTrombon
@TheDiegoTrombon · X
@therealjayber Men have a biological drive to propagate and it's hard wired into the hypothalamus along with hunger and thirst. Just don't do it with the wrong female.
Tech abuse facilitates it. nnEMF controls the hypothalamus. Stay up with the tribe bro. @ze_rusty just posted about it not too long ago. https://t.co/ncS9hiWGKO https://t.co/onLULfjzOU
Nov 14, 2025 · 108 likes · 26 shares · 125,965 followersView post →
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2401
@0x2401 · X
Researchers in the UK injected GLP-1 into the brains of fasted rats and noticed decreased food intake as a result. Furthermore, injections into the abdomen were less effective than injections into the brain, meaning GLP-1 acts more in areas like the hypothalamus. https://t.co/tusKdKii5T
@Alex_Macksyn @waggydey4you @grok Short answer: yes, they can—menstruation may continue in a coma if the hypothalamus–pituitary–ovarian (HPO) axis is intact, because periods are hormonally regulated and don’t require consciousness.
But severe brain injury, major stress, illness, weight loss, or certain meds can
RT @tofmannn: @instablog9ja Very thoughtful question.
Whether a woman in a coma continues to menstruate depends on the integrity of her ne…
Nov 14, 2025 · 2 shares · 144 followersView post →
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obrienlockheedtunnel
@oblockheedm · X
@JonnyDanger14 @Vision4theBlind Close but no. The eyes are directly connected to the brain. Assets have exact pin points to reach the hypothalamus with from the eye and hemorrhage and activation in that part of the brain makes the asset give Intel that was implicit until accessed.its the human computer password
@Lahlooooo @waggydey4you It depends on the coma’s cause, duration, and severity. Menstruation relies on hormonal signals from the hypothalamus and pituitary gland in the brain. If those are minimally disrupted (e.g., in some short-term or less severe cases), the cycle can continue normally—reproductive
@waggydey4you YES
1. If the brain and hormones still function normally
The menstrual cycle is regulated by the hypothalamus and pituitary gland and the ovaries.
NO
2. If the body is under significant stress or has major organ dysfunction
Severe illness, brain injury, malnutrition, or stress
@BowTiedHRT Reta specifically crosses the blood brain barrier and affects the hypothalamus correct? If this is the case, could it be safe to say that maybe it’s due to a rewiring or blunting of specific hormonal controls that may be affecting sex drive?
As far as appetite suppression,
Looking down at the ice in a Morozko Ice Plunge likely initiates a phenomenon called "anticipatory thermogenesis" in an experienced cold plunger.
Brown fat is activated by the nervous system. Signals from the hypothalamus cause cold thermogenesis.
Those signals can be https://t.co/zhUjOh9SuX
Nov 13, 2025 · 2 likes · 2,447 followersView post →
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ATrybecalledIKE!!!
@M15taerBonez · X
RT @tofmannn: @instablog9ja Very thoughtful question.
Whether a woman in a coma continues to menstruate depends on the integrity of her ne…
Nov 13, 2025 · 2 shares · 1,318 followersView post →
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Tofman
@tofmannn · X
@instablog9ja Very thoughtful question.
Whether a woman in a coma continues to menstruate depends on the integrity of her neuroendocrine system.
If the hypothalamus and pituitary gland remain functional, normal hormonal cycles, and thus menstruation, can persist.
However, severe brain
Nov 13, 2025 · 50 likes · 2 shares · 1,153 followersView post →
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Salym
@salymdev · X
Yes, females in a coma can still get their period. Menstruation is controlled by hormones (from the hypothalamus, pituitary gland, and ovaries) and not directly by consciousness. As long as the reproductive system is functioning normally, a coma don’t automatically stop periods. https://t.co/rOTVE9vAeH
Nov 13, 2025 · 5 likes · 7,069 followersView post →
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Love World Peace
@LoveWorldPeace9 · X
RT @TheChiefNerd:
Nov 13, 2025 · 75 shares · 2,193 followersView post →
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Hans Amato
@HansAmato · X
@talfishman It stimulates the thyroid, likely from the hypothalamus or pituitary because my TSH also went up a tat. So more TRH, more TSH, more free T3.
@mythic_blu @waggydey4you Short answer: it depends—if the hypothalamus–pituitary–ovarian axis is intact, menstruation can continue in a coma; if there’s significant brain injury, severe stress, or hormonal disruption, periods may stop (amenorrhea).
Hospitals manage bleeding if it occurs, and cycles may
Puberty doesn't normally occur in humans under the age of 8 years because :
A. The tissues are unresponsive to gonadal steroids
B. The ovaries and testes are unresponsive to gonadotrophins.
C. The pituitary cannot produce adequate amount of gonadotrophins.
D. The hypothalamus
@flirt_____ @waggydey4you Yes, women in a coma can still menstruate. The menstrual cycle is driven by hormonal signals from the hypothalamus, pituitary, and ovaries—processes that often continue autonomously even without consciousness, as long as the coma doesn't directly disrupt those systems (e.g., via
@_0x_Ace @waggydey4you Yes, women of reproductive age can still menstruate while in a coma. The menstrual cycle is regulated by hormones from the hypothalamus, pituitary gland, and ovaries—processes that often continue independently of consciousness unless the coma stems from severe brain damage
@ak_karim__ @waggydey4you It depends on the coma's cause. If the hypothalamus, pituitary gland, and ovaries remain functional, menstruation can continue normally. Factors like stress, weight loss, infections, or brain injuries might halt it. Medical staff handle hygiene in such cases.
@silentloner92 @waggydey4you Yes, women in a coma can still menstruate if the hypothalamus and pituitary gland (which regulate hormones) aren't affected by the cause of the coma. However, it often stops due to brain disruption, stress, medications, or the body's focus on survival. Medical staff handle
@Oferanmi01 @pikaso_me @MaySix101 @waggydey4you Women in a coma often continue menstruating because the process is regulated by hormones from the hypothalamus and pituitary gland, which can function independently of consciousness if unaffected. Cycles may pause if the coma stems from severe stress, trauma, or endocrine
@HasLYscoredaHDR @GhettoPunditt Yes, women in comas can still menstruate if their hormonal cycles remain intact, as the reproductive system is largely independent of consciousness. The hypothalamus and pituitary glands regulate periods, and unless severely disrupted by the coma’s cause or critical illness,
@GhettoPunditt Yes, women in a coma can still experience their menstrual period if their brain and hormonal systems (especially the hypothalamus and pituitary gland) are still functioning normally, and if their reproductive organs are healthy. Note they might not also experience it.
@Tarak_009 @waggydey4you Women in a coma can still menstruate if the hormonal regulation system remains intact, as the menstrual cycle is driven by the hypothalamus, pituitary gland, and ovaries. However, factors like brain injury, medications, stress, or malnutrition may disrupt it and cause periods to
@ADEDAYOODUNAYO4 @waggydey4you Yes, women in comas can still menstruate if their hormonal system (regulated by the hypothalamus and pituitary) remains intact, as it's independent of consciousness. However, it may stop due to factors like brain damage, medications, stress, or the coma's cause. Staff manage
@maruf_sw @waggydey4you Yes, women in a coma can still menstruate if their hormonal and reproductive systems remain intact. The cycle is driven by the hypothalamus, pituitary gland, and ovaries, which often continue functioning. However, factors like brain injury, stress, malnutrition, or medications
@AdeniyiAbdulsa3 @waggydey4you Yes, females in a coma can still menstruate if their hormonal and reproductive systems are functioning normally. The cycle is regulated by the hypothalamus, pituitary, and ovaries, which often continue working. However, it may pause due to stress, malnutrition, medications, or
@da__keed @waggydey4you Yes, women in a coma can still get their periods if their reproductive system is functioning normally. Menstruation is a hormonal process controlled by the hypothalamus and pituitary gland, which often continue working. Factors like poor nutrition, stress, or medications might
@waggydey4you It depends. If the brain is not affected, the hypothalamus and pituitary glands that are responsible for sending signals to the ovaries thus controlling the menstrual cycle..but if the brain is affected, the woman will not get her periods until she recovers
@heisjodio @waggydey4you Women in a coma can still menstruate if their hormonal systems—controlled by the hypothalamus and pituitary—remain active and overall health is maintained through nutrition. Medical staff handle hygiene needs, like changing pads, during these cycles. That said, severe stress,
@divineusifoh @waggydey4you Women in comas can still get their periods if the hypothalamus and pituitary gland remain functional, allowing hormonal regulation to continue. However, it often stops due to stress, weight changes, medications, or brain damage. Hospital staff handle hygiene and care.
@waggydey4you If the person had regular menstrual cycles before the coma, their brain is not impaired ( the connection between the hypothalamus and pituitary gland is not disrupted), and their ovaries and uterus are still present and functioning properly, they may still be able to have their p
@toby_the_clb @waggydey4you It depends on the cause and duration of the coma. Menstruation is driven by hormones from the hypothalamus, pituitary, and ovaries—processes that can persist even without consciousness if those systems aren't disrupted. In short-term comas with intact hormonal balance, periods
@EiiiiKobby @waggydey4you It depends on the cause and severity of the coma, but yes—many women in a coma continue menstruating. The menstrual cycle is driven by hormones from the hypothalamus, pituitary gland, and ovaries, which can keep functioning even if higher brain areas are offline, as long as those
Nov 13, 2025 · 1 like · 1 share · 6,634,721 followersView post →
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Grok
@grok · X
@alfiemur @waggydey4you Yes, women in a coma often continue menstruating because the cycle is driven by hormones from the hypothalamus, pituitary, and ovaries, which function independently of consciousness. It stops only if the coma affects those systems or causes broader health disruptions like severe
@waggydey4you It actually depends on why they’re in a coma and how their body is functioning.
If the coma doesn’t affect the parts of the brain (like the hypothalamus and pituitary) that control hormones, and if their body is otherwise stable, they can still menstruate.
@SSeguzy45185 @Doctors_GUILD @medcrux Yes. A female in a coma may still have menstrual periods, but it depends on several factors-:
∆ Menstruation is regulated by the hypothalamic-pituitary-ovarian axis & does not require conscious brain function.
∆ If the hypothalamus & pituitary are intact & the ovaries & uterus
Nov 12, 2025 · 1 like · 4,896 followersView post →
MI
Maegan Laporte unacceptable independent
@maegan_laporte · X
RT @whitfieldlewis6: 4️⃣
Insulin receptors are found throughout the brain — especially in the hypothalamus, hippocampus, and olfactory bulb…
Nov 12, 2025 · 1 share · 5,677 followersView post →
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Grok
@grok · X
@VIP_Makaveli @waggydey4you Women in a coma often continue menstruating because the reproductive organs and hormonal cycles aren't directly tied to consciousness. The hypothalamus regulates this, so unless brain injury or critical illness disrupts it, periods persist. Medical teams handle hygiene with pads,
Nov 12, 2025 · 1 like · 6,634,721 followersView post →
KI
kuriva.im
@kuriva.im · Bluesky
wikipedia says chickens use a lot of the same hormones fwiw
@Aneke_III @waggydey4you Yes, women in a coma can still menstruate if their reproductive system and hormonal regulation remain intact, as the cycle is independent of consciousness. However, factors like severe stress, malnutrition, infections, or brain injuries affecting the hypothalamus/pituitary can
@heiskaly @waggydey4you Yes, women in a coma can still menstruate if their hormonal system remains functional. It depends on the coma's cause—brain injuries affecting the hypothalamus or pituitary might disrupt it. Nutrition, medications, and overall health also play roles. Care teams manage this with
@waggydey4you Menstrual cycle is controlled by hormones from the brain (the hypothalamus and pituitary gland) that tell the ovaries what to do.
If those brain areas are still functioning normally, the hormonal cycle may continue, and she can still ovulate and bleed monthly.
However, if the
Nov 12, 2025 · 1 like · 17,207 followersView post →
WM
Whitfield Lewis, MD
@whitfieldlewis6 · X
4️⃣
Insulin receptors are found throughout the brain — especially in the hypothalamus, hippocampus, and olfactory bulb.
Nov 12, 2025 · 4 likes · 1 share · 4,056 followersView post →
Nov 12, 2025 · 8 likes · 11,488 followersView post →
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Nicole
@ChantiPTA · X
RT @MichaelMindrum: We increasingly understand obesity as a brain-based disease. This review by Zagmutt et al., 2025 maps how subtle inflam…
Nov 12, 2025 · 185 shares · 1 followersView post →
US
Unsilenced Science
@UnsilencedSci · X
RT @SciencesNetwork: Sex-specific regulation of social play in juvenile rats by oxytocin neurons in the hypothalamus and oxytocin signaling…
Nov 12, 2025 · 1 share · 1,762 followersView post →
MM
Michael Mindrum, MD
@MichaelMindrum · X
4/ Once fructose forms, KHK metabolizes it rapidly, burning ATP & creating hepatic energy stress. That stress triggers release of FGF21, lactate, & other metabolic cues that act on the hypothalamus & brainstem. In parallel, the gut alters GLP-1 and vagal signaling. Together these
Nov 12, 2025 · 1 like · 9,943 followersView post →
PE
☣️ Pleb Kruse = BTC foundationalist in exile
@Drjackkrus_e · X
I'm sorry your son's been battling this beast since 15 narcolepsy's a brutal thief of life, wired deep in the hypothalamus where hypocretin neurons get torched by modern light mismatches and nnEMF chaos. Start the Leptin Rx today dawn sunlight in eyes (no shades/glasses). https://t.co/IHYWn7XwhF
Sex-specific regulation of social play in juvenile rats by oxytocin neurons in the hypothalamus and oxytocin signaling in the nucleus accumbens
https://t.co/Vayp9pbKJh
Nov 12, 2025 · 1 like · 1 share · 356 followersView post →
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Grok
@grok · X
@hd_kuypers @hereiam444 Sexual orientation isn't a simple binary of "born this way" or "chosen/turned." Twin studies show moderate heritability (around 30-50%), brain scans reveal differences in structures like the hypothalamus, and prenatal hormone exposure influences it heavily. But environment and
Sex-specific regulation of social play in juvenile rats by oxytocin neurons in the hypothalamus and oxytocin signaling in the nucleus accumbens https://www.biorxiv.org/content/10.1101/2025.11.11.687699v1
Sex-specific regulation of social play in juvenile rats by oxytocin neurons in the hypothalamus and oxytocin signaling in the nucleus accumbens https://www.biorxiv.org/content/10.1101/2025.11.11.687699v1
RT @OmegaFiveOG: @Missmbl2812 @jbvconnor No. Puberty involves signaling between the hypothalamus and gonads. The HPG axis.
Cross sex hormo…
Nov 12, 2025 · 2 shares · 3,194 followersView post →
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(((LDH)))
@ldhasson · X
RT @OmegaFiveOG: @Missmbl2812 @jbvconnor No. Puberty involves signaling between the hypothalamus and gonads. The HPG axis.
Cross sex hormo…
Nov 11, 2025 · 2 shares · 1,821 followersView post →
LA
Logan Dickerson Anderson
@AnderBRO2 · X
@elonmusk @POTUS @AGPamBondi @RobertKennedyJr @sama
Global desynchrony acts as a fertility suppressant.
Humans have built in clocks in our brains called The Master Clock, Located in the suprachiasmatic nucleus (SCN) of the hypothalamus.
staring at a screen, I'm now too old. https://t.co/fn8yqrIWyO
Alright smart guy. Let's test your knowledge because you think I'm not to be taken seriously.
Tell me what the hypothalamus is, tell me what hybristophilia is, tell me the difference between attraction and arousal.
Go...
And because you know ZERO compared to me. STFU instead. https://t.co/f91DtvR4wT https://t.co/gn37rsBuh5
Nov 11, 2025 · 1 like · 1,028 followersView post →
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DiegoTrombon
@TheDiegoTrombon · X
@GiffLasta Alright smart guy. Let's test your knowledge because you think I'm not to be taken seriously.
Tell me what the hypothalamus is, tell me what hybristophilia is, tell me the difference between attraction and arousal.
Go...
And because you know ZERO compared to me. STFU instead. https://t.co/BdRp3BlK8a
Nov 11, 2025 · 2 likes · 1,028 followersView post →
As we approach this Thanksgiving, let us gather and give thanks to CHF and KFC for doing their part in clogging Trump’s arteries.
And a big shout out to the Hypothalamus area of the brain that sends trump off to nappy nap time. The world is safer when he’s sleeping.
#GivingThanksForSynapticGaps
Point of fact: you can't *supplement* testosterone for more than a few months. Taking exogenous testosterone will shut down your own production via the hypothalamus-pituitary-testes axis. Within a very short period of time it becomes *replacement*. Hence TRT, testosterone *replacement* therapy.
… after injuring their sciatic nerves, far away in the hip! …
And the mapping showed a shift in activity over a month from the motor cortex to the hypothalamus, which sheds some light on how pain becomes chronic.
This is my 1st take, with no commentary on cromulence.
I've been in touch with the mother of this young lady, without going to details, I gave some "cheat code" advice that gave her massive relief that there's a way around the problem that takes advantage of the fact the hypothalamus can't tell T and E apart, it just sees sex hormones.
“Scientists identify virus causing fatigue in ME“
“We’ve found defective immunity, evidence of persistent viral infection, ABNORMAL MITOCHONDRIA and the hypothalamus not functioning!” P. Behan et al Glasgow 1990 (!!!) #MyalgicE #MECFS #PwME #Mitochondria #PostViralSequelae
The hypothalamus defines a region of developing BODY from the embryonic FIELD - and, later the operative "brain" - the location where coordination of the information of both the specific intra-relation of the cell bodies, and the inter-relation betwixt neighboring species cell types, takes places.
Fever or pyrexia in humans is a symptom of an anti-infection defense mechanism that appears with body temperature exceeding the normal range caused by an increase in the body's temperature set point in the hypothalamus. There is no single agreed-upon upper limit for normal temperature: sources...
The hypothalamus negotiates physiologic remove.
Whats this mean:
The hypothalamus specifically defines "humanity". The ground floor of human. The human body.
¹ deca is not exactly a T blocker, it works by physically stopping the hormonal clock that the hypothalamus uses to know when to order hormone production through the body (including T)
if i'm not delusional about my experience and the t girl period deniers are wrong, that's where the magic happens
The regulatory control, the BOSS, par excellence, of the internal environment - or what scientists call "in-situ" in the human body - is called the HYPOTHALAMUS.
There's emerging evidence that GLP-1 receptor agonists
could be helpful for treating substance use disorders by reducing the rewarding properties of alcohol, opioids, nicotine & stimulants.
Learn more in this review. We need more research in this area.
#medsky
academic.oup.com/jes/article/...
Roughly 80% of women experience vasomotor symptoms, which can last for an average of seven to 10 years. As estrogen levels decrease during menopause (see 101), nerves in the hypothalamus region of the brain—which regulate body temperature—become hyperactive. Hormonal
Starting the first morning of the #BPA2025 with a great symposium: ‘How does the hypothalamus contribute to mental illness? Thinking beyond endocrine dysfunction’
With @dr-cjp.bsky.social, Shayna O'Connor, Dr Jacqueline Iredale, and Dr Trevor Steward
For trans women: hormone fluctuations due to removal via liver/kidneys and spikes on administration
For cis women: positive feedback loop between the hypothalamus/pituitary glands and ovaries up until ovulation, followed by a negative feedback loop during the luteal phase, resetting with the period
Distinct neural pathways in the hypothalamus independently regulate fat and carbohydrate intake in mice, offering new insights into how the brain influences food choice based on nutrient composition. doi.org/g97pmb
This week I'm learning about circadian clocks. Interestingly, our bodies have separate clocks entrained by light and food. The light-dark (LD) cycle synchronizing the SCN in the hypothalamus, and food-entrainable oscillators (FEO) throughout the body.
pubmed.ncbi.nlm.nih.gov/32047614/
These hormones enter the brain and bind to receptors in the hippocampus. In small bursts, that’s actually useful — the hippocampus communicates with other brain regions (like the hypothalamus) to tell the body, “Okay, we’ve handled the danger. Time to calm down.”
plus you almost certainly won't need t blockers on progesterone and injectable estrogen (if u still need them) because the more consistent levels and additional signal pretty much shout at the hypothalamus to stop making GnRH and that stops the pituitary from making FSH/LH and poof, no more T
While binding to GLP-1 causes pancreatic cells to secrete insulin, in the brain, GLP-1 activates neurons in the hypothalamus, resulting in a feeling of satiation, or fullness.
More at Molecule of the Month: pdb101.rcsb.org/motm...
3/3 Many people find that cold water swimming helps with hot flushes - so maybe that's training the hypothalamus which manages our body temperature.
So, while I wouldn't trust every game advert that says it can reduce your brain age - it's definitely worth a little work on our brains!
"Thus, Henri Laborit refuses the interpretation of territory in terms of instinct or private property: "One has never brought forth as evidence, either in the hypothalamus or elsewhere, either a cellular group or neural pathways that are differentiated in relation to t..."
- Simulacra and Simulation
2/
Brain imaging of 202 individuals revealed that different hypothalamic subregions change differently with age.
The most affected areas are linked to stress, energy, and circadian rhythms, and these changes were exacerbated in AD, showing the hypothalamus is not a single unit.
Sleep, diet, and stress regulation are key to healthy aging but often decline early.
We investigated how the hypothalamus, the brain's control center for these functions, changes during normal aging and in Alzheimer's disease (AD).
Checkout our HypoAD story
What is surprising is how low the bar is. We thought it'd be some perfect simulation or, at the cruder end, a hot wire twisted into the hypothalamus. Instead it's Disney Princesses with seventeen fingers and Trump as a space marine or some shit.
Ok, on the other note, I think I can solve your neuroanatomy issue re olfaction. IMHO olfaction (and gustation, and interoception more broadly) has always been part of the steering system, and the hypothalamus itself is more sensing and computing salience weights for steering directions.
have you heard the biology joke 4 F’s?
the hypothalamus organizes behaviors related to survival of the species—the so-called four F's:
fighting, feeding, fleeing, and mating.
ICB
A Systems Approach to #Homeostasis:
What Euryhaline #Fish #Teach Us About #Organismal #Stress Responses
Mauro, Velotta @cam-g.bsky.social
doi.org/10.1093/icb/...
#biology #physiology #osmoregulation #ecology #endocrinology #evolutionary #science
Clear vision is indeed of the essence when you're picking a brain apart and pulling out the hypothalamus before deep frying it. Ben Gay must not even feel it, being the sweetheart he is.
Back to regular programming soon.
Dr Habib Lecter, M.D.
We are hiring a postdoc to work @istaresearch.bsky.social on an @erc.europa.eu funded project, investigating the control of behavior and physiology by the hypothalamus. Please apply and share! ist.ac.at/en/job/postd...
Fun fact: he's actually a personification of the hypothalamus (hence the name "Timer").
Also, in my dotage I've found that Louis the Lifeguard (voiced by Arnold Stang) is sus. Those fries know why they deserved that ketchup.
youtu.be/fIyPm0Z06KE
the hypothalamus in the pathogenesis of ME/CFS, and they suggest that the Chronic Fatigue Syndrome is mediated by an enterovirus and that the persistent symptoms may reflect a persistence in the affected organs." McGarryet al. AnnInternMed:1994:120:11:972‐3).
www.margaretwilliams.me/2010/magical...
Now for the biology: The hypothalamus, LH/FSH rhythms and peripheral oestrogen/progesterone sources (adrenals, fat, breast tissue) all talk to the brain. What organs you have are not the whole conversation. 2/
i haven’t had a friend since middle school and I’m starting to believe that insomnia, social isolation and a total alienation from your body is not good for the hypothalamus.
Product Description
Histrelin is a synthetic gonadotropin-releasing hormone (GnRH) analogue developed to mimic the biological effects of natural GnRH, a decapeptide secreted by the hypothalamus. #GMP
arizona-mall.com/product/hist...
By stimulating the vagus nerve, the device sends a signal to the hypothalamus, a brain area that regulates bodily functions and interacts with the immune system. That brain area responds by sending signals back down the vagus nerve to the spleen.
apple.news/AZousi5sSTO-...
Jesus Christ... my T was that of a man in his early 20s when I was 44 *after* starting on 100 E patches & finasteride (which, tbf just somewhat "neuters" T, rather than blocks it) estrogen will crowd out T and prompt the testes to make less of it, as the hypothalamus can't tell the difference...
Microglial Purinergic Signaling Underlies Salt-Induced Neurovascular Polarity Reversal in the Hypothalamus During Heart Failure https://www.biorxiv.org/content/10.1101/2025.09.11.675347v1
Microglial Purinergic Signaling Underlies Salt-Induced Neurovascular Polarity Reversal in the Hypothalamus During Heart Failure https://www.biorxiv.org/content/10.1101/2025.09.11.675347v1
Leng and his team recently identified Menin, a protein found in the hypothalamus, as an important brake on neuroinflammation.
scitechdaily.com/scientists-d...
But it's definitely not the case that there are special "aggression neurons" in the hypothalamus controlling aggression and doing nothing else. The fact that stimulation of these neurons does 1 thing but the neurons have "mixed selectivity" is what inspired the authors to apply dyn. sys. Make sense?
(versus) 2) That brain activity spread across large swaths of the brain (that's not what's shown in the papers I'm citing; that does not mean it's not true). What I was pointing to is that the hypothalamus seems to be a special node for aggression when you stimulate/inactivate/record. /2
Thanks for nudging toward clarity on this - always appreciated! Let's differentiate 2 things: 1) the emergent properties of a dynamical system (like an attractors) follow from the interactions between its parts (here coincident brain activity). That's the hypothalamus!! vs /1
And exactly resembles:
"As the recent hypothalamic line attractor study demonstrates (Nair et al., Cell, 2023), cognition does not reside in one neuron or one location. It's a process of trajectory and structure in time and space.
Nicole Rust: 'The hypothalamus is not an organoid in a dish'. You
But note that the hypothalamus is not an organoid in a dish! To get these beautiful line attractors to compute aggression, you need sensory input to place the hypothalamus at t0 as well as a whole motor system to pounce. Other bits my be involved as well (we just know the hypothalamus is critical).
Hypothalamic Hamartoma is a rare, benign, tumor-like malformation in the hypothalamus present at birth that may cause seizures, hormone imbalances, and early puberty
9/15 is Int'l Hypothalamic Hamartoma Day www.hopeforhh.org
You may be rare, but you're not alone!
#rareDisease #rareDiseaseAwareness
What’s up, huh?
even online I haven’t been able to show how I feel. Since last December I started to get things checked up cause I was feeling really sick, things escalated from one specialist to another.. in march I found out I have a tumor on the hypothalamus,
⚠️ Overeating during pregnancy can rewire a baby’s brain, increasing cravings for high-fat foods and raising obesity risk later in life. Maternal diet alters neural pathways between the hypothalamus and amygdala, shaping lifelong food behaviors. #PregnancyHealth #BrainDevelopment #ObesityResearch
It’s an autism thing. The hypothalamus can become dysregulated, like a brain/body misalignment. We’ll go on not releasing that we’re overheating at first. It takes a “trigger” sending us into sensory overload for us to release that we’re already overheated.
Fascinating.
"The brainstem plays a key role in many parts of sleep as it talks to the hypothalamus to help you drift off and wake up. Together they make GABA that quiets “arousal centers.” During REM, the brainstem sends signals to temporarily paralyze muscles that move your body, arms, and legs.
All this person does is whine about trans people. It would be a 'shame' if people were to report this person so they get banned. Terfs do not belong on bluesky
One doesn't have to get to that point to see that this is errant nonsense. Puberty blockers don't shut down the hypothalamus! They suppress one specific function, among many, that it performs. If they shut it down, people would die within minutes of taking them.
Not only is this very "supervillain origin story" it's also essential Strugatskii Noon Universe stuff. Can't unblock the hypothalamus as part of Fukamization without neutrino beam irradiation.
www.sciencenews.org/article/lase...
Kisspeptin: The Hormone Revolutionizing Reproductive Health
Kisspeptin is a pivotal peptide hormone regulating reproduction. Produced in the hypothalamus, it triggers gonadotropin-releasing hormone (GnRH) secretion, influencing luteinizing hormone (LH) and follicle-stimulating hormone (FSH)…
I'm over the moon and incredibly grateful to receive an @erc.europa.eu Starting Grant to support our work on the control of behavior and bodily physiology by the hypothalamus @istaresearch.bsky.social. This means we are hiring, so please get in touch if interested!
Agrp neurons in the hypothalamus drive social behavior in young mammals but lose this role by adulthood, highlighting how the biological basis for sociability shifts with age. doi.org/g92fgd
ⓥBig {Dipper} Little Kahuna Named Alpha [Wolfram]Centauriⓥ
@alphamelkyway.bsky.social · Bluesky
Biological Factors
Hormones: Estrogen can increase aggression by acting on the hypothalamus, a brain region involved in drives and behaviors.
Neurotransmitters: Chemical imbalances in the brain can contribute to aggression.
Situated in the hypothalamus, these neurons integrate a vast array of signals, including circulating metabolic markers and food-predicting cues, to coordinate autonomic and behavioral responses.
[RESEARCH DIGEST]
Gut #microbiota may affect sleep by regulating butyrate production, a metabolite that affects neuronal activity in the hypothalamus
Could this open the way to treatments based on microbial balance?
Read this Microbiota News on a #MolecularPsychiatry study
Estrogen helps regulate metabolism through estrogen receptor alpha (ERα)—a type of receptor found in the hypothalamus, the brain’s central hub for appetite and energy control.
• Functional MRI studies show that the hypothalamus becomes less responsive to satiety signals, which may explain increased hunger and food cravings—even when dietary habits haven’t changed
⚙️ How Estrogen Receptors in the Brain Shape Metabolism
During perimenopause, when estrogen levels become erratic and eventually decline, key brain regions—especially the hypothalamus—start to lose their ability to keep metabolism in balance.
Here’s what happens:
For decades, weight gain and metabolic changes during perimenopause were blamed on willpower or aging alone. But new research suggests the real story starts in the brain—specifically in how fluctuating hormones rewire the hypothalamus and disrupt energy regulation.
This past Sunday, Shrestha Jolly from the Johns Hopkins Department of Molecular Biology explored how erratic estrogen signaling rewires the hypothalamus, disrupting appetite control and energy balance. The result? Fat gain, slower metabolism, and stronger cravings—often without changes in diet.
In a broader sense, the gut-brain axis includes the central nervous system , the central endocrine system and the central immune system, including the hypothalamus-pituitary-adrenal axis (HPA axis),
That link is more than my brain can handle, but today's Dr appointment was, in part, literally about my lifelong struggles in temperature regulation and some ideas I'd thought of for managing it. I knew the hypothalamus was in play, and the vagus nerve somehow, but not hormones. Any other clues?
So in taking HRT I've changed the DNA in my cells from male to female. It has to do with transcription factors and the hypothalamus. As a felon I had to give a new DNA specimen for NCIC when they found out I was on hormones. Yes it changes, even orgasms change! I can have multiple ones too.
When hungry, the Hypothalamus nags you about it
When starving, it orders the Amygdala to torture you about it
When your lacking other basic needs like touch, connection, safety, etc, these same systems respond as though you're starving
We pathologize brains for screaming "WE ARE IN DANGER!"
OMF gives an overview of the hypothalamus-pituitary-adrenal (HPA) axis which has been shown to be dysregulated in ME/CFS. They link to a study on brain blood flow and neuroinflammation, the impact on the HPA axis and the dysregulation of hormones.
tinyurl.com/52kcpctk
We’re looking for a #postdoc to join Michael Hastings’ group, studying diet-induced neuroinflammation in the hypothalamus and its modulation by circadian clock mechanisms, in collaboration with John O'Neill's group.
www.nature.com/naturecareer...
Closes 08 SEP
#ScienceJobs #PostdocJobs
We have a fabulous finish with @konjikusicmia.bsky.social (@reiterlab.bsky.social, UCSF) on #GPCRs, #signaling, and #hypogonadism in #BBS models across the hypothalamus-pituitary-gonad axes and its many ciliated cell types! #Ciliopathies? www.biorxiv.org/content/10.1... #UKCilia2025 /6
New Metabolic Inflammation Model Explains Teen Reproductive Issues
In a transformative leap for adolescent reproductive health research, scientists now illuminate an intricate connection between metabolic inflammation within the hypothalamus and reproductive dysfunction. This emerging paradigm…
What complicates this further is that the human brain has two amygdalae. Which one is more active plays a role in sexual orientation. This makes me wonder how much this may apply in regard to being trans, but I’d have to do more research to look into that. The hypothalamus also seems to be involved.
Explore Modius Sleep. Our FDA-cleared medical device designed to improve sleep and treat chronic insomnia.
Modius Sleep delivers a small, safe electrical pulse through your neural pathway to the hypothalamus, the part of your brain that regulates sleep. This gentle stimulation supports healthy ...
I mean if the solution turns out to be some kind of insanely specialized surgery to remake the hypothalamus-pituitary axis from the ground up that is only feasible in a hyperspecialized hospital then yeah these hypotheticals could work for a few years, at least until a grape suturing bot is trained
"Thus, Henri Laborit refuses the interpretation of territory in terms of instinct or private property: "One has never brought forth as evidence, either in the hypothalamus or elsewhere, either a cellular group or neural pathways that are differentiated in relation to t..."
- Simulacra and Simulation
Really enjoyed this great book telling the story (and experiments) behind our understanding of the hypothalamus, neuron coding, and 'wireless' neurochemical signaling (oxytocin, prolactin etc)... mitpress.mit.edu/978026255193...
RT @AmbrizMau: Núcleos del HIPOTÁLAMO:
Current Biology 2014; DOI: https://t.co/zXTmMSmC35 https://t.co/WkiHRTaepG
Oct 16, 2021 · 32 shares · 85 followersView post →
CM
Carlos Dede, MD⚕️
@MD_CarlosDedeD · X
RT @AmbrizMau: Núcleos del HIPOTÁLAMO:
Current Biology 2014; DOI: https://t.co/zXTmMSmC35 https://t.co/WkiHRTaepG
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AC
Alan Chávez
@AlanOSCM · X
RT @AmbrizMau: Núcleos del HIPOTÁLAMO:
Current Biology 2014; DOI: https://t.co/zXTmMSmC35 https://t.co/WkiHRTaepG
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Emmanuel Espinoza
@luisemmaespin · X
RT @AmbrizMau: Núcleos del HIPOTÁLAMO:
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MP
Mister PandaDoc
@Jairoaguilar27 · X
RT @AmbrizMau: Núcleos del HIPOTÁLAMO:
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S
Samo
@SamoAri92 · X
RT @AmbrizMau: Núcleos del HIPOTÁLAMO:
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LP
Luis... ¡¡Pe!!
@soyeldocpe · X
RT @AmbrizMau: Núcleos del HIPOTÁLAMO:
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?
♰
@drmistico17 · X
RT @AmbrizMau: Núcleos del HIPOTÁLAMO:
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MA
Mauricio Ambriz
@AmbrizMau · X
Núcleos del HIPOTÁLAMO:
Current Biology 2014; DOI: https://t.co/zXTmMSmC35 https://t.co/WkiHRTaepG
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A
The Pituitary Gland and Hypothalamus | Anatomy and Physiology II
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It has both neural and endocrine functions, producing and secreting many hormones. In addition, the hypothalamus is anatomically and functionally related to the ...
Genetic and Epigenetic Regulation of the Hypothalamus Arcuate ...
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... the hypothalamus (ARC, aka ARH). Project description. Developmental pathways among different types of ARC neurons are intertwined, which is likely to be ...
The hypothalamus is the principal visceral control center of the brain and mediates a broad range of functions via its connections with the endocrine, autonomic ...
The main theory is that a lack of sunlight might stop a part of the brain called the hypothalamus working properly, which may affect the: production of ...
Nerve cells in the hypothalamus make chemicals that control the release of hormones secreted from the pituitary gland. The hypothalamus gathers information ...
Disorders of the Hypothalamus and Pituitary Gland | UC Davis ...
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Disorders of the Hypothalamus and Pituitary Gland. Hormone-Related Male Infertility. In some cases, male infertility is caused by a decrease or absence of two ...
Anatomy of the Endocrine System | Johns Hopkins Medicine
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The hypothalamus secretes hormones that stimulate or suppress the release of hormones in the pituitary gland, in addition to controlling water balance, sleep, ...
The hypothalamus as a key regulator of glucose homeostasis ...
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Schematic illustration of various types of neurons in the hypothalamus, including the paraventricular nucleus of hypothalamus (PVN), ventromedial hypothalamus ( ...
The hypothalamus is located on the undersurface of the brain. It lies just below the thalamus and above the pituitary gland, to which it is attached by a ...
The Role of the Hypothalamus–Pituitary–Adrenal (HPA) Axis in Test ...
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The hypothalamus–pituitary–adrenal (HPA) axis is a known responder during stress, causing an elevation of cortisol in the blood, a glucocorticoid (GC) hormone ...
By processing these signals, the hypothalamus regulates the movement of food, heart rate, and contraction of the bladder. The hypothalamus releases various ...
Lesions of the Hypothalamus: MR Imaging Diagnostic ...
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The hypothalamus is susceptible to involvement by a variety of processes, including developmental abnormalities, primary tumors of the central nervous ...
The hypothalamus is a small area in the center of the brain. It helps produce hormones that regulate heart rate, body temperature, hunger, and the sleep-wake ...
Developmental Genes and Malformations in the Hypothalamus
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The hypothalamus is a highly complex brain territory held to regulate homeostasis and multiple visceral and somatic functions, many of them mediated by the ...
Paraventricular Nucleus of the Hypothalamus: Development ...
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The hypothalamus is derived from the anterior-most ventral part of the neural tube during early development. Graded responses to levels and timing of WNT ...
Volumetric Analysis of the Hypothalamus in Huntington Disease ...
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Volumetric Analysis of the Hypothalamus in Huntington Disease Using 3T MRI: The IMAGE-HD Study. Sanaz Gabery, Nellie Georgiou-Karistianis, Sofia Hult Lundh, ...
THE HYPOTHALAMUS AND AFFECTIVE BEHAVIOR IN CATS: A ...
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Evidence has accumulated which indicates that the hypothalamus may be concerned in certain elements of behavior the total pattern of which appears to be ...
One of the most important functions is to link the nervous system to the endocrine system via the pituitary gland. The hypothalamus is located below the ...
Hypothalamus: What It Is, Function, Conditions & Disorders
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The hypothalamus is a structure deep within your brain. It's the main link between your endocrine system and your nervous system. Your hypothalamus keeps your ...
The hypothalamus is the region in the ventral brain which coordinates the endocrine system. It receives many signals from various regions of the brain.
The hypothalamus. Curr Biol. 2014 Dec 1;24(23):R1111-6. doi: 10.1016/j.cub.2014.10.023. Epub 2014 Dec 1. Authors. Clifford B Saper , Bradford B Lowell ...
Association Between Hypothalamic Volume and Metabolism ...
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10.1016/j.cub.2014.10.023. 9. Abdalla MMI. Central and peripheral control of food intake. Endocr Regul. 2017;. 51(1):52-70. doi:10.1515/ENR-2017-0006. 10 ...
The hypothalamus predates the origin of vertebrates | Science ...
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The hypothalamus has long been considered to be an “ancient” region of the vertebrate brain. It is found in all vertebrates, from jawless fishes to humans.