On top of this somatic mosaicism of point mutations and copy number variations is the epigenetic factor: specific parts of the genome are chemically modified by the cell's machinery in a manner that varies between individuals. https://t.co/SGJYGdOiFK
Epigenetics of discordant monozygotic twins: implications for disease.
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Aug 2019 – Jan 2023Where it's discussed
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X / Twitter10 posts
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News4 articles
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Blogs4 articles
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YouTube2 videos
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Facebook2 posts
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What people are saying
These discussions highlight the significance of epigenetic factors, with comments about somatic mosaicism and gene modifications, demonstrating both curiosity and acknowledgment of the research's potential. The tone conveys both technical understanding and an appreciation for the implications in disease understanding and personalized medicine.
Most discussions acknowledge the importance and relevance of the research on epigenetic differences in monozygotic twins, indicating general agreement with the publication's significance.
Participants show moderate interest, often referencing the potential for personalized medicine and the complexities of epigenetic factors.
Conversations include comments on the mechanisms and implications, such as somatic mosaicism and gene regulation, demonstrating a fair level of engagement.
The discussions reflect an understanding that this research could influence future studies and medical approaches, indicating a recognition of its potential impact.
Abstract in brief
- Monozygotic twins share nearly all their genes and environments but can still differ in traits due to epigenetic differences, which are reversible gene regulation marks influenced by genetics, environment, and random events.
- Research on discordant MZ twins (twins with different traits or disease states) allows scientists to study epigenetic factors contributing to diseases like aging, cancer, and autoimmune disorders while controlling for genetic and early-life environmental variables.
- Findings from these studies have potential applications in personalized medicine by identifying epigenetic markers for disease risk, prognosis, and treatment, though challenges like sampling and tissue-specific differences still need to be addressed.]
Top posts
Most liked on X and BlueskyRT @c0nc0rdance: On top of this somatic mosaicism of point mutations and copy number variations is the epigenetic factor: specific parts of…
RT @SMCADMAN: Epigenetics of discordant monozygotic twins: implications for disease https://t.co/RIjw9qSQeE
Epigenetics of discordant monozygotic twins: implications for disease https://t.co/RIjw9qSQeE
#epigenetics Epigenetics of discordant monozygotic twins https://t.co/NTTQdA9UZT
RT @c0nc0rdance: On top of this somatic mosaicism of point mutations and copy number variations is the epigenetic factor: specific parts of…
All mentions
Epigenetics and Disease in Discordant Monozygotic Twins
Monozygotic twins share nearly all their genes but can differ in traits due to reversible epigenetic differences influenced by genetics, environment, and random events. Studying discordant twins helps identify…
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RT @c0nc0rdance: On top of this somatic mosaicism of point mutations and copy number variations is the epigenetic factor: specific parts of…
RT @c0nc0rdance: On top of this somatic mosaicism of point mutations and copy number variations is the epigenetic factor: specific parts of…
On top of this somatic mosaicism of point mutations and copy number variations is the epigenetic factor: specific parts of the genome are chemically modified by the cell's machinery in a manner that varies between individuals. https://t.co/SGJYGdOiFK
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RT @SMCADMAN: Epigenetics of discordant monozygotic twins: implications for disease https://t.co/RIjw9qSQeE
Epigenetics of discordant monozygotic twins: implications for disease https://t.co/RIjw9qSQeE
#epigenetics Epigenetics of discordant monozygotic twins https://t.co/NTTQdA9UZT
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