Genome Med December 2014 PMID 25484923

Epigenetics of discordant monozygotic twins: implications for disease.

Juan E Castillo-Fernandez, Tim D Spector, Jordana T Bell

Mentions

22
Peak: 4 in Jan 2022
across 5 sources since Aug 2019

Extended reach

159,831
potential audience

Total likes

10,899

Video views

118,833

Mentions per month

Aug 2019 – Jan 2023

Where it's discussed

  • X / Twitter10 posts
  • News4 articles
  • Blogs4 articles
  • YouTube2 videos
  • Facebook2 posts

AI synopsis

What people are saying

These discussions highlight the significance of epigenetic factors, with comments about somatic mosaicism and gene modifications, demonstrating both curiosity and acknowledgment of the research's potential. The tone conveys both technical understanding and an appreciation for the implications in disease understanding and personalized medicine.

AgreementModerate agreement

Most discussions acknowledge the importance and relevance of the research on epigenetic differences in monozygotic twins, indicating general agreement with the publication's significance.

InterestModerate interest

Participants show moderate interest, often referencing the potential for personalized medicine and the complexities of epigenetic factors.

EngagementModerate engagement

Conversations include comments on the mechanisms and implications, such as somatic mosaicism and gene regulation, demonstrating a fair level of engagement.

ImpactModerate impact

The discussions reflect an understanding that this research could influence future studies and medical approaches, indicating a recognition of its potential impact.

Abstract in brief

  • Monozygotic twins share nearly all their genes and environments but can still differ in traits due to epigenetic differences, which are reversible gene regulation marks influenced by genetics, environment, and random events.
  • Research on discordant MZ twins (twins with different traits or disease states) allows scientists to study epigenetic factors contributing to diseases like aging, cancer, and autoimmune disorders while controlling for genetic and early-life environmental variables.
  • Findings from these studies have potential applications in personalized medicine by identifying epigenetic markers for disease risk, prognosis, and treatment, though challenges like sampling and tissue-specific differences still need to be addressed.]

Top posts

Most liked on X and Bluesky
c0nc0rdance
@c0nc0rdance · X

On top of this somatic mosaicism of point mutations and copy number variations is the epigenetic factor: specific parts of the genome are chemically modified by the cell's machinery in a manner that varies between individuals. https://t.co/SGJYGdOiFK

Jan 2, 2023 · 22 likes · 2 shares · 9,840 followers View post →
(((Liz Ditz))). Mask up, y'all. Viruses are real.
@lizditz · X

RT @c0nc0rdance: On top of this somatic mosaicism of point mutations and copy number variations is the epigenetic factor: specific parts of…

Jan 9, 2023 · 2 shares · 10,485 followers View post →
Sara
@SMCADMAN · X

RT @SMCADMAN: Epigenetics of discordant monozygotic twins: implications for disease https://t.co/RIjw9qSQeE

Sep 27, 2020 · 1 share · 6,348 followers View post →
Sara
@SMCADMAN · X

Epigenetics of discordant monozygotic twins: implications for disease https://t.co/RIjw9qSQeE

May 1, 2020 · 1 share · 6,348 followers View post →
SeqComplete
@SeqComplete · X

#epigenetics Epigenetics of discordant monozygotic twins https://t.co/NTTQdA9UZT

Aug 18, 2019 · 4,395 followers View post →
Joshua Richards
@joshuaprichards · X

RT @c0nc0rdance: On top of this somatic mosaicism of point mutations and copy number variations is the epigenetic factor: specific parts of…

Jan 3, 2023 · 2 shares · 2,657 followers View post →

All mentions

Epigenetics and Disease in Discordant Monozygotic Twins

Monozygotic twins share nearly all their genes but can differ in traits due to reversible epigenetic differences influenced by genetics, environment, and random events. Studying discordant twins helps identify…

Smash · Jan 27, 2022 118,713 views
(((Liz Ditz))). Mask up, y'all. Viruses are real.
@lizditz · X

RT @c0nc0rdance: On top of this somatic mosaicism of point mutations and copy number variations is the epigenetic factor: specific parts of…

Jan 9, 2023 · 2 shares · 10,485 followers View post →
Joshua Richards
@joshuaprichards · X

RT @c0nc0rdance: On top of this somatic mosaicism of point mutations and copy number variations is the epigenetic factor: specific parts of…

Jan 3, 2023 · 2 shares · 2,657 followers View post →
c0nc0rdance
@c0nc0rdance · X

On top of this somatic mosaicism of point mutations and copy number variations is the epigenetic factor: specific parts of the genome are chemically modified by the cell's machinery in a manner that varies between individuals. https://t.co/SGJYGdOiFK

Jan 2, 2023 · 22 likes · 2 shares · 9,840 followers View post →
село приховане в понтах
@drakoniatko_ · X

посмотрите какой он красивый и помните что защиту https://t.co/eoFRegdwfS

Feb 17, 2022 · 46 followers View post →
kris vald
@Iife_is_suicide · X

https://t.co/DQyUzS1nSV ОН ТАКОЙ СОФТ

Jan 28, 2022 · 715 followers View post →
Изя
@hDK5P5Ai54BwrAf · X

ВЕСНУШКИ! https://t.co/zFLHlSSLIR via @YouTube

Jan 27, 2022 · 68 followers View post →
lokky
@lokky7 · X

ВЕСНУШКИ! https://t.co/3559uqky3c через @YouTube

Jan 27, 2022 · 80 followers View post →
Sara
@SMCADMAN · X

RT @SMCADMAN: Epigenetics of discordant monozygotic twins: implications for disease https://t.co/RIjw9qSQeE

Sep 27, 2020 · 1 share · 6,348 followers View post →
Sara
@SMCADMAN · X

Epigenetics of discordant monozygotic twins: implications for disease https://t.co/RIjw9qSQeE

May 1, 2020 · 1 share · 6,348 followers View post →
SeqComplete
@SeqComplete · X

#epigenetics Epigenetics of discordant monozygotic twins https://t.co/NTTQdA9UZT

Aug 18, 2019 · 4,395 followers View post →