PubHawk
January 2015 PMID 25517348

A randomized trial of intraarterial treatment for acute ischemic stroke.

Olvert A Berkhemer, Puck S S Fransen, Debbie Beumer, Lucie A van den Berg, Hester F Lingsma, Albert J Yoo, Wouter J Schonewille, Jan Albert Vos, Paul J Nederkoorn, Marieke J H Wermer, Marianne A A van Walderveen, Julie Staals, Jeannette Hofmeijer, Jacques A van Oostayen, Geert J Lycklama à Nijeholt

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Mentions

206
Peak: 7 in Jan 2020
across 6 sources since Dec 2014

Extended reach

274,566
potential audience

Total likes

181

Video views

25,962

Mentions per month

Dec 2014 – Dec 2023

Where it's discussed

  • Facebook102 posts
  • News38 articles
  • X / Twitter31 posts
  • Blogs29 articles
  • YouTube4 videos
  • Reddit2 posts

AI synopsis

What people are saying

Discussions frequently highlight the trial’s role in transforming stroke treatment, with phrases like ‘ended all other trials’ and ‘revolutionized stroke care,’ showing a shared understanding of its impact. The tone is enthusiastic and acknowledges the trial as a major milestone, supported by references to clinical practice changes and specific results, such as improved outcomes and the significance of the NEJM publication.

AgreementStrong agreement

Most discussions strongly agree that the MR CLEAN trial was a pivotal study that revolutionized stroke treatment.

InterestHigh interest

Participants show high interest, often mentioning the trial as a ‘game changer’ and emphasizing its significance in stroke care.

EngagementHigh engagement

Posts reference specific trial outcomes and implications, indicating deep engagement with the research's methodology and impact.

ImpactHigh impact

There is widespread recognition of the study’s transformative influence on medical practice and guidelines.

Abstract in brief

  • Intraarterial treatment shows promise for improving functional outcomes in acute ischemic stroke patients compared to usual care alone, based on a study with 500 participants.
  • The primary outcome, measured by the modified Rankin scale, indicated a significant improvement in functional independence (32.6% vs. 19.1%) for those receiving the intervention.
  • No notable differences were found in mortality rates or instances of symptomatic intracerebral hemorrhage between the two groups.
Read the full abstract

Top posts

Most liked on X and Bluesky
David T. Parrella, MD
@davetp · X

@drjohnm https://t.co/iyQfX6JVa8. The trial that ended all other trials for stroke thrombectomy. Revolutionized stroke care.

May 30, 2022 · 26 likes · 2 shares · 1,123 followers View post →
NeuroVascu lab Brussels
@neurovascu_lab · X

Did you know ? Mechanical Thrombectomy for Stroke with large-vessel-occlusion was proved effective very recently ! For 5 years we can officially recommend and perform it ! Read the first amazing paper published in the NEJM, Mr CLEAN ! https://t.co/TmsJQCRZbM @nejm #stroke https://t.co/btDtxntOh4

Jan 3, 2020 · 20 likes · 7 shares · 3,136 followers View post →
Adam Cifu
@adamcifu · X

Read this article today in our Critical Appraisal course. It contains the paragraph below. Sounds like something @VPrasadMDMPH and I have called for (and something that, I expect, would kill @michelaccad and @anish_koka). https://t.co/5rS1Lve6iK https://t.co/SASAEi6IXp

Feb 19, 2020 · 17 likes · 2 shares · 26,022 followers View post →
Saurabh Jha
@RogueRad · X

@AdamRodmanMD @adamcifu @VPrasadMDMPH Not sure this is what you're looking for. But I found MR CLEAN trial interesting. It reversed the preceding null trials of IAT because of better patient selection https://t.co/gj1rpZD8pO

Dec 22, 2022 · 3 likes · 15,643 followers View post →
CIRSE European Trainee Forum
@ETF_IRtrainees · X

Part I of important thrombectomy studies: A Randomised Trial of Itraarterial Treatment for Acute Ischemic Stroke (MR CLEAN) https://t.co/KRexqIKOQp #topicofthemonth #neurointervention https://t.co/KmNsjeIIhn

Mar 3, 2021 · 3 likes · 1 share · 1,553 followers View post →
John Mandrola, MD
@drjohnm · X

Dec 20, 2023 · 2 likes · 68,598 followers View post →

All mentions

John Mandrola, MD
@drjohnm · X

Dec 20, 2023 · 2 likes · 68,598 followers View post →
Saurabh Jha
@RogueRad · X

@AdamRodmanMD @adamcifu @VPrasadMDMPH Not sure this is what you're looking for. But I found MR CLEAN trial interesting. It reversed the preceding null trials of IAT because of better patient selection https://t.co/gj1rpZD8pO

Dec 22, 2022 · 3 likes · 15,643 followers View post →
苗子猫 @mys_721tx@genomic.social
@mys_721tx · X

https://t.co/OyF2lc0NRf // 荷兰有一个中风临床研究叫MR CLEAN...

Jun 11, 2022 · 606 followers View post →
Giuseppe Biondi-Zoccai
@gbiondizoccai · X

RT @davetp: @drjohnm https://t.co/iyQfX6JVa8. The trial that ended all other trials for stroke thrombectomy. Revolutionized stroke care.

May 31, 2022 · 2 shares · 12,166 followers View post →
David T. Parrella, MD
@davetp · X

@drjohnm https://t.co/iyQfX6JVa8. The trial that ended all other trials for stroke thrombectomy. Revolutionized stroke care.

May 30, 2022 · 26 likes · 2 shares · 1,123 followers View post →
Saurabh Jha
@RogueRad · X

@drvyom @drjohnm RCTs for IAT were negative until MR CLEAN. https://t.co/gj1rpZD8pO

May 8, 2022 · 2 likes · 15,643 followers View post →
Daño Cerebral Castilla-La Mancha
@adaceclm · X

RT @CreCeadac:

Feb 11, 2022 · 1 share · 2,034 followers View post →
Ceadac
@CreCeadac · X

Feb 11, 2022 · 1 like · 1 share · 7,269 followers View post →
curzen
@ncurzen · X

RT @drandrewsharp: @ncurzen @BCIS_uk The paper that changed everything. Note the date. https://t.co/pmGWqhU2VC

Oct 9, 2021 · 1 share · 4,964 followers View post →
Andrew Sharp
@drandrewsharp · X

@ncurzen @BCIS_uk The paper that changed everything. Note the date. https://t.co/pmGWqhU2VC

Oct 9, 2021 · 2 likes · 1 share · 6,892 followers View post →
scottie stob
@ermedale · X

RT @Maclomaclee: @BAZ__17 @Jim1Jas @2351onthelist @RogueCoder250 @Sparky77600125 @WeirderRieces @AyrshireBog @Rab_Ha_Glasgow @J4cobite @erm…

Jun 4, 2021 · 3 shares · 1,008 followers View post →
KatB
@Kat_Bee_123 · X

RT @Maclomaclee: @BAZ__17 @Jim1Jas @2351onthelist @RogueCoder250 @Sparky77600125 @WeirderRieces @AyrshireBog @Rab_Ha_Glasgow @J4cobite @erm…

Jun 3, 2021 · 3 shares · 6,990 followers View post →
bellesareblue
@bellesareblue · X

RT @Maclomaclee: @BAZ__17 @Jim1Jas @2351onthelist @RogueCoder250 @Sparky77600125 @WeirderRieces @AyrshireBog @Rab_Ha_Glasgow @J4cobite @erm…

Jun 3, 2021 · 3 shares · 2,139 followers View post →
Malcolm Macleod #FBPE
@Maclomaclee · X

@BAZ__17 @Jim1Jas @2351onthelist @RogueCoder250 @Sparky77600125 @WeirderRieces @AyrshireBog @Rab_Ha_Glasgow @J4cobite @ermedale @DarkSideoDunoon @Mc40400451David @ChannelUK1 @Amalkadog @daffy5dugs @SensibleScots @ScotDeveloper @bellesareblue @Occamschainsaw2 @carmic3 @pjnichols @ScotReal @SandyRogerson1 @fhirinn @ReginaldBrads10 @Mike_Fox01 @IanDePendence @ZuluAlpha_1 @Artisans17 @MoiraWetherell @dealatrip @Munky12 @Chris4man80 @BillTosh8 @gorbalsgoebbels @StrongbowsPub @scotfax @steveja89368890 @armygrad24 @CDexter05990923 @StewartNial @EnoughScotland @KellyMcSlater @jgoffshore @5DAZ5 @BillGall14 @Aloce84336601 @Pr0jectZeus @JackieMackay17 @GameLandAmazing https://t.co/EPbzED7CBh ... about 400 patients a year treated in England, only a handful in Scotland. We talk the talk, but stroke patients in Scotland deserve better ..

Jun 3, 2021 · 2 likes · 3 shares · 1,921 followers View post →
Patrick Crowley
@PCrowleyDO · X

HOLD UP. Neurologist and neurosurgeons ran a study on endovascular stroke treatment and called it MR CLEAN!?!? https://t.co/EdaFfsS7Yb

Jun 2, 2021 · 595 followers View post →
HARSH SINGH
@Harsh1986Singh · X

RT @ETF_IRtrainees: Part I of important thrombectomy studies: A Randomised Trial of Itraarterial Treatment for Acute Ischemic Stroke (MR CL…

Mar 3, 2021 · 1 share · 1,033 followers View post →
CIRSE European Trainee Forum
@ETF_IRtrainees · X

Part I of important thrombectomy studies: A Randomised Trial of Itraarterial Treatment for Acute Ischemic Stroke (MR CLEAN) https://t.co/KRexqIKOQp #topicofthemonth #neurointervention https://t.co/KmNsjeIIhn

Mar 3, 2021 · 3 likes · 1 share · 1,553 followers View post →
Shibley
@dr_shibley · X

A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke | NEJM https://t.co/Qk3ZLzKjj9

Feb 18, 2021 · 1 like · 27,497 followers View post →
Josh
@josh_scrubs · X

I'm screaming they called the clinical trial for mechanical thrombectomy MR CLEAN https://t.co/dpifWIg92u

Sep 13, 2020 · 1 like · 164 followers View post →
Amara Creed
@EvaAnge70483124 · X

RT @adamcifu: Read this article today in our Critical Appraisal course. It contains the paragraph below. Sounds like something @VPrasadMDMP…

Feb 23, 2020 · 2 shares · 12 followers View post →
Ash Paul
@pash22 · X

RT @adamcifu: Read this article today in our Critical Appraisal course. It contains the paragraph below. Sounds like something @VPrasadMDMP…

Feb 19, 2020 · 2 shares · 32,280 followers View post →
Adam Cifu
@adamcifu · X

Read this article today in our Critical Appraisal course. It contains the paragraph below. Sounds like something @VPrasadMDMPH and I have called for (and something that, I expect, would kill @michelaccad and @anish_koka). https://t.co/5rS1Lve6iK https://t.co/SASAEi6IXp

Feb 19, 2020 · 17 likes · 2 shares · 26,022 followers View post →
André Luis N Albano MD
@AlbanoNeuroVasc · X

RT @NeuroUnited: Did you know ? Mechanical Thrombectomy for Stroke with large-vessel-occlusion was proved effective very recently ! For…

Jan 4, 2020 · 7 shares · 104 followers View post →
Dr.Khadija Alfaqih
@kaf_khadija · X

RT @NeuroUnited: Did you know ? Mechanical Thrombectomy for Stroke with large-vessel-occlusion was proved effective very recently ! For…

Jan 4, 2020 · 7 shares · 1,245 followers View post →
Крестный ёж Андрусь
@Yozhik_Alissa · X

RT @NeuroUnited: Did you know ? Mechanical Thrombectomy for Stroke with large-vessel-occlusion was proved effective very recently ! For…

Jan 3, 2020 · 7 shares · 356 followers View post →
Juan Calleja
@juankalleja · X

RT @NeuroUnited: Did you know ? Mechanical Thrombectomy for Stroke with large-vessel-occlusion was proved effective very recently ! For…

Jan 3, 2020 · 7 shares · 1,678 followers View post →
Pedro Magalhaes
@Neurorradio · X

RT @NeuroUnited: Did you know ? Mechanical Thrombectomy for Stroke with large-vessel-occlusion was proved effective very recently ! For…

Jan 3, 2020 · 7 shares · 1,933 followers View post →
The French Brain Doctor
@GuenegoAdrien · X

RT @NeuroUnited: Did you know ? Mechanical Thrombectomy for Stroke with large-vessel-occlusion was proved effective very recently ! For…

Jan 3, 2020 · 7 shares · 2,908 followers View post →
NeuroVascu lab Brussels
@neurovascu_lab · X

Did you know ? Mechanical Thrombectomy for Stroke with large-vessel-occlusion was proved effective very recently ! For 5 years we can officially recommend and perform it ! Read the first amazing paper published in the NEJM, Mr CLEAN ! https://t.co/TmsJQCRZbM @nejm #stroke https://t.co/btDtxntOh4

Jan 3, 2020 · 20 likes · 7 shares · 3,136 followers View post →
Erasmus MC Public Health
@ErasmusMCPH · X

#CMB has also been involved in the MR CLEAN trial, which showed effectiveness for intraarterial treatment plus usual care would be more effective than usual care alone in #stroke patients with a proximal arterial occlusion. #sectionhighlight https://t.co/fm1zk6aoyP https://t.co/AlJxJN5sKy

Aug 27, 2019 · 2 likes · 775 followers View post →
AT@脳外科専修医
@medic34392444 · X

A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke N Engl J Med 2015; 372: 11-20 （急性虚血性脳卒中に対する発症6時間以内の動脈内治療は有効かつ安全である）

Jun 26, 2019 · 164 followers View post →