June 2016 PMID 25588755

Oxidative stress: a concept in redox biology and medicine.

Helmut Sies

Download social card

Mentions

Peak: 1 in Mar 2021

across 5 sources since Mar 2021

Extended reach

2,019

potential audience

Total likes

Video views

216

Mentions per month

Mar 2021 – Nov 2025

Where it's discussed

X / Twitter4 posts
Facebook4 posts
YouTube3 videos
News3 articles
Blogs2 articles

AI synopsis

What people are saying

The discussions reflect a balanced appreciation of the article's insights, with posts emphasizing molecular mechanisms and health implications, using terminology like 'redox switches' and 'stress response,' which indicates thoughtful engagement but not overwhelming enthusiasm or critique.

AgreementModerate agreement

Most discussions acknowledge the importance of oxidative stress and its scientific relevance, supporting the concepts presented in the publication.

InterestModerate interest

The posts show moderate curiosity, discussing mechanisms like molecular switches and cellular energy balance, indicating a genuine interest in the topic.

EngagementModerate engagement

Participants reference specific biological processes such as phosphorylation and redox signaling, demonstrating an active level of engagement.

ImpactModerate impact

The discussions suggest an appreciation of oxidative stress's significance, especially in aging and health, hinting at its broader impact in biomedical research.

Abstract in brief

Oxidative stress is a key concept in redox biology and medicine, first introduced in 1985, with extensive research and over 138,000 PubMed entries by 2015, highlighting both its importance and challenges.
The concept emphasizes the balance of redox states during aerobic metabolism and the stress responses triggered by disruptions in this balance, with current research focusing on molecular switches and signaling pathways involved.
However, a major challenge is that the detailed molecular mechanisms vary across different cases, leading to potential overgeneralization of the term without always clearly relating it to redox chemistry; antioxidant enzymes play a primary role in defense rather than small molecules.]

Read the full abstract