A double-blind randomized study comparing the association of Retinol and LR2412 with tretinoin 0.025% in photoaged skin.

Anne Bouloc, Andre Luiz Vergnanini, Maria Claudia Issa

March 2015 J Cosmet Dermatol

Synopsis of Social media discussions

The group appears mildly interested, with some posts mentioning the use of topical treatments without expressing strong opinions or detailed analysis, such as comments on the tolerability of different formulations. The tone is neutral, emphasizing factual aspects rather than emotional or provocative language, suggesting a cautious but modest recognition of the study's relevance.

A
Agreement
 Neither agree nor disagree

The discussions do not strongly agree or disagree with the publication; some post neutral or factual comments.

I
Interest
 Moderate level of interest

Participants show moderate curiosity, especially about the clinical implications, but overall engagement remains limited.

E
Engagement
 Neutral engagement

Few posts delve deeply into methodology or long-term impacts, indicating superficial engagement.

I
Impact
 Neutral impact

The discussions are brief and lack indication of significant influence or change in practice.

Social Mentions

YouTube

3 Videos

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1 Posts

News

6 Articles

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3 Posts

Metrics

Video Views

161,903

Total Likes

5,942

Extended Reach

290,842

Social Features

13

Timeline: Posts about article

Top Social Media Posts

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  • 静岡皮膚科(2024年3月開業/静岡駅徒歩3分)院長　江畑慧
    @shizuoka_doctor (Twitter)

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Abstract Synopsis

  • The study compared the effectiveness and tolerance of a combination of Retinol 0.2% and LR2412-2% versus tretinoin 0.025% in women with photoaged skin over 3 months, finding both treatments improved skin features like wrinkles, pigmentation, and pores with no significant differences in clinical outcomes.
  • Retinol 0.2%/LR2412-2% was generally better tolerated, causing milder side effects compared to tretinoin, and women perceived it as equally or more effective.
  • Overall, Retinol 0.2%/LR2412-2% offers a comparable efficacy to tretinoin with improved tolerability and perception, making it a suitable alternative for skin rejuvenation.]