Obes Rev February 2015 PMID 25614203

The role for adipose tissue in weight regain after weight loss.

P S MacLean, J A Higgins, E D Giles, V D Sherk, M R Jackman

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Mentions

169

Peak: 8 in Dec 2023

across 5 sources since Feb 2019

Extended reach

1,066,913

potential audience

Total likes

21,810

Video views

954,966

Mentions per month

Feb 2019 – Jul 2025

Where it's discussed

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AI synopsis

What people are saying

The social discussions reflect a focus on the biological and physiological aspects of weight regain, with comments like 'el rol del adipocito' and notes on metabolic adaptations, showing interest in scientific explanations. The tone suggests curiosity and acknowledgment of complex mechanisms rather than outright disagreement or excitement, with some posts emphasizing the need for proper training and understanding of body processes.

AgreementNeither agree nor disagree

The discussions recognize the importance of adipose tissue in weight regain, but also emphasize other factors like muscle communication and homeostatic balance, indicating a nuanced view.

InterestModerate interest

Participants show some curiosity about the biological mechanisms involved, especially regarding cellular communication and metabolic adaptations, but overall engagement remains moderate.

EngagementModerate engagement

Many posts reference specific concepts from the publication, such as adipose tissue's role and homeostasis, showing a decent level of discussion and thought.

ImpactModerate impact

The discussion highlights the biological basis of weight regain, which could influence future considerations in weight management strategies, suggesting a moderate impact.

Abstract in brief

The article discusses how adipose tissue (fat tissue) plays a key role in why people often regain weight after losing it, especially focusing on changes in white adipose tissue (WAT) that promote overeating and weight regain.
When weight loss occurs, fat cells shrink, which changes their metabolic and inflammatory properties, making the body more likely to store energy and drive feelings of hunger, leading to weight regain.
The authors propose that signals about stored energy and nutrient availability come from changes in adipose tissue cellularity, which are processed in the brain regions responsible for hunger and energy regulation, explaining the persistent biological drive to regain lost weight.]

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TJ Jurkiewicz | Fat Loss Coach

@TheFitnessJurk · X

Jul 22, 2025 · 5,989 followers View post →

Karla Ziegler

@mariposatuitera · X

RT @javierbutra: Y sólo estamos viendo el rol del adipocito, pero si hemos dicho en otros tweet que se comunica con el músculo, ¿Qué creéis…

Jan 7, 2024 · 2 shares · 26,760 followers View post →

Karla Ziegler

@mariposatuitera · X