J Crit Care June 2015 PMID 25669592

A systematic review of extravasation and local tissue injury from administration of vasopressors through peripheral intravenous catheters and central venous catheters.

Osama M Loubani, Robert S Green

Mentions

32
Peak: 9 in Oct 2022
across 7 sources since Jun 2015

Extended reach

23,330
potential audience

Total likes

178

Video views

5,055

Mentions per month

Jun 2015 – Nov 2025

Where it's discussed

  • Reddit10 posts
  • News9 articles
  • Blogs6 articles
  • Bluesky3 posts
  • YouTube2 videos
  • X / Twitter1 posts
  • Facebook1 posts

AI synopsis

What people are saying

The discussions analyze the safety of peripheral vasopressor infusions, with posts citing specific data like infusion durations of around 55 hours, and some participants debating complications and best practices, emphasizing a nuanced understanding of the article's findings through technical language and clinical context.

AgreementModerate agreement

Most users acknowledge the findings, highlighting the balance between peripheral and central line use, with some emphasizing the safety of short-term peripheral administration.

InterestHigh interest

Discussions reflect high curiosity due to clinical relevance, with mentions of infusion durations and complication rates.

EngagementModerate engagement

Posts include specific data points like infusion times and incidents, showing moderate active engagement rather than passive reading.

ImpactModerate impact

The posts discuss practical implications such as earlier use of peripheral lines and safety considerations, indicating a moderate influence on clinical practice.

Abstract in brief

  • This systematic review examined reports of tissue injury or extravasation caused by vasopressor drugs administered through peripheral or central IVs, analyzing data up to January 2014.
  • A total of 85 articles involving 270 patients were included, with most tissue injury events (204 out of 270) resulting from peripheral IV vasopressor infusions, which typically lasted around 24 hours.
  • The review highlights that most injuries occurred at sites distal to major joints, and emphasizes the need for further research to better understand the safety of peripheral vasopressor administration.

Top posts

Most liked on X and Bluesky
Anthony Lau, PharmD BCPS
@alaurx.bsky.social · Bluesky

Before, we've stuck to central lines for pressors to avoid extravasation but waiting for CL isn't an option when profoundly hypotensive. Short-term peripheral admin of pressors is safe. Complications arise after ~55h of infusion #medsky #EMsky #nursesky #pharmsky pubmed.ncbi.nlm.nih.gov/25669592/

Nov 18, 2024 · 23 likes · 11 shares View post →
Vitor Borin P. de Souza
@vitorborin_ · X

@anabenzaprina @miauhelo @camomiwa Olha, casos de extravasamento são bem raros e mesmo assim, necrose local é mais rara ainda. Pra acontecer nos 4 membros? Ou alguém fez algo muito errado ou não foi os vasopressores. https://t.co/FPj012qffa +

Jun 26, 2023 · 1 like · 17,994 followers View post →
Anthony Lau, PharmD BCPS
@alaurx.bsky.social · Bluesky

"There were 204 local tissue injury events from peripheral administration of vasopressors, with an average duration of infusion of 55.9 hours (±68.1), median time of 24 hours, and range of 0.08 to 528 hours." #medsky #EMsky #nursesky #pharmsky pubmed.ncbi.nlm.nih.gov/25669592/

Nov 18, 2024 View post →
Gav
@dentongavin.bsky.social · Bluesky

A systematic review of extravasation and local tissue injury from administration of vasopressors through pvc or cvc http://www.wessexics.com/The_Bottom_Line/Review/index.php?id=6892495633638977747

Jun 27, 2015 View post →

All mentions

Safety of Norepinephrine Infusions in Surgery

This video discusses the safety of using norepinephrine infusions through peripheral IV lines during surgery. With a review of 14,385 patients, the study suggests a very low risk of complications, significantly aiding…

Ta de Clinicagem · Jan 29, 2023 4,898 views
Anthony Lau, PharmD BCPS
@alaurx.bsky.social · Bluesky

"There were 204 local tissue injury events from peripheral administration of vasopressors, with an average duration of infusion of 55.9 hours (±68.1), median time of 24 hours, and range of 0.08 to 528 hours." #medsky #EMsky #nursesky #pharmsky pubmed.ncbi.nlm.nih.gov/25669592/

Nov 18, 2024 View post →
Anthony Lau, PharmD BCPS
@alaurx.bsky.social · Bluesky

Before, we've stuck to central lines for pressors to avoid extravasation but waiting for CL isn't an option when profoundly hypotensive. Short-term peripheral admin of pressors is safe. Complications arise after ~55h of infusion #medsky #EMsky #nursesky #pharmsky pubmed.ncbi.nlm.nih.gov/25669592/

Nov 18, 2024 · 23 likes · 11 shares View post →
Vitor Borin P. de Souza
@vitorborin_ · X

@anabenzaprina @miauhelo @camomiwa Olha, casos de extravasamento são bem raros e mesmo assim, necrose local é mais rara ainda. Pra acontecer nos 4 membros? Ou alguém fez algo muito errado ou não foi os vasopressores. https://t.co/FPj012qffa +

Jun 26, 2023 · 1 like · 17,994 followers View post →
Gav
@dentongavin.bsky.social · Bluesky

A systematic review of extravasation and local tissue injury from administration of vasopressors through pvc or cvc http://www.wessexics.com/The_Bottom_Line/Review/index.php?id=6892495633638977747

Jun 27, 2015 View post →
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