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Discussions reflect positively on the publication, highlighting the combination of dasatinib and quercetin as a notable breakthrough in senolytic research. Phrases such as 'Gold Standard in Senolytic research' and 'transformative potential' convey excitement and optimism regarding the article's implications. Posts also showcase a desire to share additional resources and further their understanding, indicating an enthusiastic response to the original study.
There is a strong consensus among discussions that the research is valuable and significant, with many expressing strong agreement with the findings.
Participants show high levels of interest, as several posts engage with the implications of the research and discuss it further.
While many posts are informative, a few demonstrate deeper engagement by analyzing specific aspects of the study and referencing related discussions.
Users perceive the research as having high potential impact, particularly in informing future treatments targeting aging and senescence.
En este #PaperEn2Min os traigo los últimos avances en terapias contra el #envejecimiento en #ratones, y que no os timen. Una vacuna contra la #senescencia celular, quidicí: células viejitas
@DrJenGunter @NatGeo Hey Jen! I agree that aging isn’t a disease* (probably, it’s an interesting biological/semantic/philosophical discussion!) but I think we can and should cure it. If you’ve got a few minutes to check out a video on why this isn’t as bonkers as it sounds: https://t.co/4JOLVE3fMX
The Achilles' heel of senescent cells: from transcriptome to senolytic drugs In old mice, cardiac function was improved 5 days after a single dose... a single dose led to improved exercise capacity for at least 7 months following drug treatment. https://t.co/yHSRv1HgyO
@waitbutwhy This is the graph that changed my career. I was a physicist, and ended up becoming a computational biologist and writing a book about the biology of aging, using medicine to flatten the curve and tackle the single largest cause of human suffering: https://t.co/4JOLVDLEon
At 75 years, the NHS is now old enough that (if it were a human!) it would likely be suffering from multiple chronic diseases. For it (another other health services) to succeed over the next 75 years, they will need to address ageing: https://t.co/4JOLVE3fMX #NHS75 #NHSBirthday
If you’d like a ten-minute introduction to the ideas in the book, you can find one on my YouTube channel: (in the video, I’m waving around the UK edition which has a different cover!) https://t.co/4JOLVE3fMX
I believe that aging is our greatest humanitarian challenge and that science can help us solve it. This video discusses how targeting senescent cells with senolytic drugs may improve healthspan and suggests promising…
The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs. https://t.co/2VDcUTQZdM
ケルセチンはフラボノイドの一種で,身近な野菜等に含まれ,強い抗酸化作用を有している ‘15年に,老化したヒト内皮細胞およびマウス骨髄由来間葉系幹細胞(BM-MSC)を効果的に死滅させ,老化マウスで抗がん剤ダサチニブとの併用の50mg/kgの単回投与でも老化細胞の減少を確認 https://t.co/Mp9M2EEdTS
This is the paper describing how dasatinib and quercetin combination came to be used as a Gold Standard in Senolytic research.... https://t.co/N5rGRpqYuT
One of the first papers describing the combination of quercetin and dasatinib for killing senescent cells. Selectively killing senescent cells. https://t.co/EVxjUhun4A
@andrewingram @HAJBlack @rauchg @jrysana Haha thanks dude! Yes, this is correct. If you’d like to know more… Short version (12-minute video): https://t.co/i8s1vrmAYR Medium version (lecture): https://t.co/sEwB2Lm5uY Long version (my book!): https://t.co/peONHGw7YE :)
RT @statto: At 75 years, the NHS is now old enough that (if it were a human!) it would likely be suffering from multiple chronic diseases.…
At 75 years, the NHS is now old enough that (if it were a human!) it would likely be suffering from multiple chronic diseases. For it (another other health services) to succeed over the next 75 years, they will need to address ageing: https://youtube.com/watch?v=tNn-2TXzSaA
RT @statto: At 75 years, the NHS is now old enough that (if it were a human!) it would likely be suffering from multiple chronic diseases.…
At 75 years, the NHS is now old enough that (if it were a human!) it would likely be suffering from multiple chronic diseases. For it (another other health services) to succeed over the next 75 years, they will need to address ageing: https://t.co/4JOLVE3fMX #NHS75 #NHSBirthday
DIESES Mittel stoppt das Altern! https://t.co/MQcyzYcvLM via @YouTube
@MinuteEarth Very happy to chat and convince you to make a second follow-up video clarifying the first follow-up. (!) You can find some more details in a video I made about this (or my book!) https://t.co/4JOLVE3fMX
@DrJenGunter @NatGeo Hey Jen! I agree that aging isn’t a disease* (probably, it’s an interesting biological/semantic/philosophical discussion!) but I think we can and should cure it. If you’ve got a few minutes to check out a video on why this isn’t as bonkers as it sounds: https://t.co/4JOLVE3fMX
@tomkinder24 @themonkeycage @ProfBrianCox @robinince @Sarah_Kendall Thanks for listening! Yes, you can see the graph in this video I made: https://t.co/TO35lMtTII (I’ve linked to the moment it appears around 1:20 in…) If you want the nerdy details, here’s they are! https://t.co/rwJf8wutnT
RT @debbieweil: I'm not thoroughly convinced... but I am thoroughly intrigued with @statto's new book, AGELESS. Plus he's a very good write…
I'm not thoroughly convinced... but I am thoroughly intrigued with @statto's new book, AGELESS. Plus he's a very good writer. "How science can reverse aging – and why we’d want to" https://t.co/irUJdusHUQ Maybe he'll come on my [B]OLDER podcast aka @debbiepodcast
@hankgreen And, most excitingly…we can do something about it. https://t.co/4JOLVE3fMX
RT @sherezade_mr: En este #PaperEn2Min os traigo los últimos avances en terapias contra el #envejecimiento en #ratones, y que no os timen.…
RT @sherezade_mr: En este #PaperEn2Min os traigo los últimos avances en terapias contra el #envejecimiento en #ratones, y que no os timen.…
RT @statto: If you’d like a ten-minute video introduction to the science of Ageless before reading the book-length version, I’ve got you co…
RT @statto: If you’d like a ten-minute video introduction to the science of Ageless before reading the book-length version, I’ve got you co…
If you’d like a ten-minute video introduction to the science of Ageless before reading the book-length version, I’ve got you covered: https://t.co/4JOLVE3fMX
RT @sherezade_mr: En este #PaperEn2Min os traigo los últimos avances en terapias contra el #envejecimiento en #ratones, y que no os timen.…
RT @sherezade_mr: En este #PaperEn2Min os traigo los últimos avances en terapias contra el #envejecimiento en #ratones, y que no os timen.…
RT @sherezade_mr: En este #PaperEn2Min os traigo los últimos avances en terapias contra el #envejecimiento en #ratones, y que no os timen.…
RT @sherezade_mr: En este #PaperEn2Min os traigo los últimos avances en terapias contra el #envejecimiento en #ratones, y que no os timen.…
RT @sherezade_mr: En este #PaperEn2Min os traigo los últimos avances en terapias contra el #envejecimiento en #ratones, y que no os timen.…
RT @sherezade_mr: En este #PaperEn2Min os traigo los últimos avances en terapias contra el #envejecimiento en #ratones, y que no os timen.…
En este #PaperEn2Min os traigo los últimos avances en terapias contra el #envejecimiento en #ratones, y que no os timen. Una vacuna contra la #senescencia celular, quidicí: células viejitas
Cure aging?! Yes please. https://t.co/2vyrjt5gR3
RT @statto: If you’d like a ten-minute introduction to the ideas in the book, you can find one on my YouTube channel: (in the video, I’m wa…
@WanderingGaia @TomChivers I’m with Tom on this! :) There are loads of promising avenues, and I’d be genuinely shocked if at least a few of them don’t pan out. If you’d like a short video intro, here’s why I think this is so important: https://t.co/4JOLVE3fMX
https://t.co/Den5ofCILA
For an explanation of why I call ageing our greatest humanitarian challenge, which might sound like a strange (perhaps even hubristic!) statement, this video lays it out: https://t.co/4JOLVE3fMX
@chydorina Kirkland’s group @MayoClinic pioneered this using a bioinformatics approach to ID compounds whose MOA target SCAP network nodes critical for preventing senescent cell apoptosis. The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs https://t.co/VsgDtbjoGN
@HulbertMathew @brit @BritandCo If you’ve not already seen it, this video explains! https://t.co/4JOLVE3fMX
RT @TheMeso: The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs https://t.co/Qe0hB0obtE @sminaev2015 @scil_leuve…
RT @TheMeso: The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs https://t.co/Qe0hB0obtE @sminaev2015 @scil_leuve…
RT @TheMeso: The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs https://t.co/Qe0hB0obtE @sminaev2015 @scil_leuve…
RT @TheMeso: The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs https://t.co/Qe0hB0obtE @sminaev2015 @scil_leuve…
RT @TheMeso: The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs https://t.co/Qe0hB0obtE @sminaev2015 @scil_leuve…
The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs https://t.co/Qe0hB0obtE @sminaev2015 @scil_leuven @scientistbiomed @PepperPell @pugliesemd @_atanas_ @sciencetracker2 @Blagosklonny
@waitbutwhy This is the graph that changed my career. I was a physicist, and ended up becoming a computational biologist and writing a book about the biology of aging, using medicine to flatten the curve and tackle the single largest cause of human suffering: https://t.co/4JOLVDLEon
(I go through how human risk of death varies with age a couple of minutes into this video…) https://t.co/4JOLVE3fMX
RT @statto: If you’d like a ten-minute introduction to the ideas in the book, you can find one on my YouTube channel: (in the video, I’m wa…
If you want to hear a bit more about why I think we should cure aging and how, check out this YouTube video! (With apologies to America that I’m holding the UK edition, and spell ageing with an e…) https://t.co/4JOLVE3fMX
@HulbertMathew @peacockTV I go into a bit more detail in this YouTube video and, of course, my book! https://t.co/4JOLVE3fMX
How can you slow your own ageing, and live long enough to benefit from the first real anti-ageing medicine? Find this out and more in Andrew Steele's (@statto) new audiobook AGELESS, now available: https://t.co/Ety4Ugliow
If you’d like a ten-minute introduction to the ideas in the book, you can find one on my YouTube channel: (in the video, I’m waving around the UK edition which has a different cover!) https://t.co/4JOLVE3fMX
@Jeunessima @behindthewoman1 I think it will be on the @SheffLibraries YouTube channel in the not-too-distant future so you'll be able to catch up! Or here’s a slightly shorter video on my YouTube channel :) https://t.co/4JOLVE3fMX
Archetypal #Senolytic Dasantinib+Quercetin selectively⏫apoptosis of senescent cells in
We all stand to gain from this https://t.co/ja43umtQK9
Fantastic book so far and works great as audiobook! Easy to follow and understand even if you're not an expert in biology. I suspect this become my favorite book on this subject once I've finished it! Make sure to watch the book intro video as well: https://t.co/ETURjlSzTa https://t.co/QnafeyJQRm
If you want to learn a bit more, here is a thread of short videos about the book: a brief intro, a bit more on the science, and a teaser about health advice. There’s also a ten-minute introduction to the book on my YouTube channel: https://t.co/4JOLVE3fMX https://t.co/DtwZMrG9v8
Want an 11-minute video introduction to my book? Check out my new video on YT: why I think we should cure ageing https://t.co/4JOLVE3fMX
RT @statto: NEW VIDEO! Why we should cure ageing: an introduction to my new book, Ageless https://t.co/4JOLVE3fMX
RT @statto: NEW VIDEO! Why we should cure ageing: an introduction to my new book, Ageless https://t.co/4JOLVE3fMX
RT @statto: NEW VIDEO! Why we should cure ageing: an introduction to my new book, Ageless https://t.co/4JOLVE3fMX
NEW VIDEO! Why we should cure ageing: an introduction to my new book, Ageless https://t.co/4JOLVE3fMX
セノリティックドラッグ（老化細胞溶解薬) ダサチニブとケルセチンの組み合わせ https://t.co/BIGey1wj2y
The Achilles' heel of senescent cells: from transcriptome to senolytic drugs In old mice, cardiac function was improved 5 days after a single dose... a single dose led to improved exercise capacity for at least 7 months following drug treatment. https://t.co/yHSRv1HgyO
RT @deoanzai: ケルセチンの論文みつけた。In vitro（試験管実験）だとケルセチンもけっこう行けてる。動物実験は抗がん剤と併用の場合だけ。ということは、単独だとあんまり効かなかった、のかな The Achilles’ heel of senescent cell…
ケルセチンの論文みつけた。In vitro（試験管実験）だとケルセチンもけっこう行けてる。動物実験は抗がん剤と併用の場合だけ。ということは、単独だとあんまり効かなかった、のかな The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs https://t.co/HSoOzkXOQs