Cell April 2015 PMID 25860609

Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis.

Jessica M Yano, Kristie Yu, Gregory P Donaldson, Gauri G Shastri, Phoebe Ann, Liang Ma, Cathryn R Nagler, Rustem F Ismagilov, Sarkis K Mazmanian, Elaine Y Hsiao

Mentions

216
Peak: 2 in Jun 2021
across 6 sources since Feb 2019

Extended reach

84,890
potential audience

Total likes

483

Video views

17,115

Mentions per month

Feb 2019 – Sep 2025

Where it's discussed

  • News93 articles
  • Facebook89 posts
  • Blogs15 articles
  • X / Twitter10 posts
  • YouTube6 videos
  • Reddit3 posts

AI synopsis

What people are saying

Discussions exhibit enthusiasm for the research's implications, with mentions of gut bacteria influencing neurotransmitter levels and overall health. The tone ranges from curiosity to excitement, exemplified by phrases like 'microbiome is how it influences the nervous system' and questions about integrating microbiology into mainstream understanding, showcasing both interest and recognition of the study's potential impact.

AgreementStrong agreement

Most discussions strongly support the idea that gut bacteria influence serotonin biosynthesis, aligning with the article's findings.

InterestHigh interest

The posts demonstrate a high level of curiosity about microbiome research, highlighting neurotransmitter production and gut-brain interactions.

EngagementHigh engagement

The social discussions include references to specific mechanisms, such as bacteria and host cell interactions, and mention notable figures, indicating deep engagement.

ImpactHigh impact

Several posts emphasize the significance of this research for health, neuroscience, and potential therapies, reflecting high perceived impact.

Abstract in brief

  • The GI tract has a lot of a chemical called serotonin, which affects how our body works, but we don't fully understand how it is made there.
  • Researchers found that special bacteria in our gut help create more serotonin by working with specific cells.
  • These bacteria and their byproducts can change how we digest food and how our blood works, showing that our gut and the bacteria living in it are really important for our health.

Top posts

Most liked on X and Bluesky
Marc Chevrette
@wildtypeMC · X

Neuro is cool, I get it, but what is it gunna take to get @MCHammer on the microbiology train? Maybe some gut-brain interface? Post your favorites. Personally, I love this work from @pipethero https://t.co/Eu6m5nHGGU

Aug 24, 2020 · 7 likes · 3,350 followers View post →
APS Division of Biological Physics
@ApsDbio · X

One of the most exciting aspects of the microbiome is how it influences the nervous system. Bacteria in the gut can regulate neurotransmitter production (https://t.co/zehULD0KC9) and directly produce certain human neurotransmitters. Thanks to @thaasophobia for this fact! https://t.co/p944wJXtDm

Jun 3, 2021 · 2 likes · 1,580 followers View post →
Hirokazu
@hirokazupapi · X

EC細胞は、短鎖脂肪酸および二次胆汁酸によっても刺激されセロトニンの合成を促進する。 https://t.co/Eh97jspUor

Aug 7, 2019 · 1 like · 48,080 followers View post →
Francisco P. Chávez
@bioBlogia · X

@GaboTuitero @radiozero977 Did yo know that 90% of the body’s total serotonin and more than 50% of the body’s total dopamine are synthesized in the gut, not in the brain? https://t.co/bGbFNMeRX8

Nov 15, 2019 · 1 like · 6,234 followers View post →
Floré by Sun Genomics
@sungenomics · X

https://t.co/5bO5eOEDS3 https://t.co/R4HOU0pfRy

Feb 21, 2019 · 1 like · 3,509 followers View post →
The GUT CLUB
@club_gut · X

Note: There is 400x more melatonin produced in the gut than the brain. And unlike gut-derived serotonin, it can cross BBB. Serotonin, precursor of melatonin, produced in the gut was shown to be mainly about Clostridia interacting with host cells (Hsaio). https://t.co/Ff2i4QaMOY

Mar 6, 2021 · 2,313 followers View post →

All mentions

おじさん
@r60369820 · X

これが2015年とかの発見らしいんで、まあそうだよね。https://t.co/jyzSTD8Kfj

Sep 6, 2025 · 590 followers View post →
iMichelR
@imichelR · X

RT @nekonoir: Gut feelings: intestinal flora regulate serotonin production http://t.co/8R5twchZPJ http://t.co/PDaSAn6K4f via @garthk and @m…

Sep 26, 2021 · 1 share · 1,077 followers View post →
APS Division of Biological Physics
@ApsDbio · X

One of the most exciting aspects of the microbiome is how it influences the nervous system. Bacteria in the gut can regulate neurotransmitter production (https://t.co/zehULD0KC9) and directly produce certain human neurotransmitters. Thanks to @thaasophobia for this fact! https://t.co/p944wJXtDm

Jun 3, 2021 · 2 likes · 1,580 followers View post →
The GUT CLUB
@club_gut · X

Note: There is 400x more melatonin produced in the gut than the brain. And unlike gut-derived serotonin, it can cross BBB. Serotonin, precursor of melatonin, produced in the gut was shown to be mainly about Clostridia interacting with host cells (Hsaio). https://t.co/Ff2i4QaMOY

Mar 6, 2021 · 2,313 followers View post →
Marc Chevrette
@wildtypeMC · X

Neuro is cool, I get it, but what is it gunna take to get @MCHammer on the microbiology train? Maybe some gut-brain interface? Post your favorites. Personally, I love this work from @pipethero https://t.co/Eu6m5nHGGU

Aug 24, 2020 · 7 likes · 3,350 followers View post →
MK
@hadasitukaeyou · X

https://t.co/lTY7WNfiIr この論文でセロトニンが迷走神経に刺激を与えて、脳に影響を与えているとのこと

May 28, 2020 · 251 followers View post →
omaflinger
@omaflinger · X

Indigenous bacteria from the gut microbiota regulate host serotonin biosynthesis https://t.co/FCICA5aCyS

Dec 7, 2019 · 791 followers View post →
Francisco P. Chávez
@bioBlogia · X

@GaboTuitero @radiozero977 Did yo know that 90% of the body’s total serotonin and more than 50% of the body’s total dopamine are synthesized in the gut, not in the brain? https://t.co/bGbFNMeRX8

Nov 15, 2019 · 1 like · 6,234 followers View post →
Hirokazu
@hirokazupapi · X

EC細胞は、短鎖脂肪酸および二次胆汁酸によっても刺激されセロトニンの合成を促進する。 https://t.co/Eh97jspUor

Aug 7, 2019 · 1 like · 48,080 followers View post →
Floré by Sun Genomics
@sungenomics · X

https://t.co/5bO5eOEDS3 https://t.co/R4HOU0pfRy

Feb 21, 2019 · 1 like · 3,509 followers View post →