The discussions reflect a strong interest in the detailed neurobiological mechanisms behind breathing regulation, exemplified by references to pioneering tools like optogenetics and related studies in different labs. Words such as 'pioneering,' 'manipulate,' and 'significance' reveal enthusiasm and recognition of the research's scientific value, though the tone remains mostly academic and cautious about immediate practical impacts.
AgreementModerate agreement
Most discussions acknowledge the significance of the research, with some references to related works highlighting its importance.
InterestHigh interest
Participants show high curiosity, especially with mentions of gene manipulation techniques and specific neuron types relevant to breathing control.
EngagementModerate engagement
The discourse indicates moderate to deep engagement, with mentions of molecular tools, related studies, and scientific journals.
ImpactModerate impact
While some posts suggest the research could influence future studies, overall impact remains slightly aspirational, emphasizing its potential rather than immediate application.
Abstract in brief
The study identifies two distinct types of sensory neurons in the vagus nerve, P2ry1 and Npy2r, which have opposing effects on breathing in mice.
P2ry1 neurons are fast-conducting fibers that, when activated, cause mice to stop breathing and stay in exhalation, while Npy2r neurons are slow-conducting fibers that induce rapid, shallow breathing when stimulated.
These neurons are anatomically connected to different parts of the brainstem and primarily target the lungs and pulmonary endocrine cells, showing that the vagus nerve contains specialized sensory lines with specific roles in breathing regulation.]
Cell (2015)
Vagal Sensory Neuron Subtypes that Differentially Control Breathing
https://t.co/KV2K2oVP0Y
Aug 15, 2022 · 43 likes · 7 shares · 28,564 followersView post →
YL
Yoav Livneh
@yoavlivneh.bsky.social · Bluesky
I would also add work from Steve Liberles lab pioneering the use of mouse molecular tools (optogenetics etc) to identify, target, and manipulate specific labeled lines of vagal sensory information:
pubmed.ncbi.nlm.nih.gov/27238020/
pubmed.ncbi.nlm.nih.gov/25892222/
This episode explores how perception influences voice production, highlighting mechanical, chemical, and subconscious responses, and their impact on breathing and voice control, based on recent neuroscience findings.
This video introduces the autonomic nervous system and explores its relationship with mindfulness meditation, highlighting its potential to improve physiological stress markers based on recent research.
I would also add work from Steve Liberles lab pioneering the use of mouse molecular tools (optogenetics etc) to identify, target, and manipulate specific labeled lines of vagal sensory information:
pubmed.ncbi.nlm.nih.gov/27238020/
pubmed.ncbi.nlm.nih.gov/25892222/