December 2015 PMID 25947369

The Glymphatic System: A Beginner's Guide.

Nadia Aalling Jessen, Anne Sofie Finmann Munk, Iben Lundgaard, Maiken Nedergaard

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Mentions

315

Peak: 4 in Nov 2022

across 6 sources since Feb 2019

Extended reach

311,003

potential audience

Total likes

2,215

Video views

77,418

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Feb 2019 – Oct 2025

Where it's discussed

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AI synopsis

What people are saying

Discussions predominantly focus on the discovery, mechanisms, and health implications of the glymphatic system, with phrases like 'brain's housekeeper' and 'nighttime washing' conveying its crucial role during sleep. The tone varies from informative to enthusiastic, reflecting both curiosity and acknowledgment of its potential importance in brain health and disease prevention.

AgreementModerate agreement

Most discussions recognize the importance of the glymphatic system, especially its role in waste clearance and sleep, indicating general agreement on its significance.

InterestHigh interest

Many posts express curiosity or highlight new discoveries, showing high interest, particularly emphasizing sleep and brain health implications.

EngagementModerate engagement

Posts range from simple mentions to discussions of mechanisms and health implications, reflecting moderate engagement with some deep insights.

ImpactModerate impact

While the recognition of the system's role in brain health suggests moderate impact, the discussions mainly focus on increasing awareness rather than immediate widespread change.

Abstract in brief

The glymphatic system is a recently discovered waste clearance system in the brain that uses perivascular tunnels formed by astroglial cells to remove waste products like proteins and metabolites, mainly during sleep.
It also helps distribute important compounds such as glucose, lipids, amino acids, and growth factors across the brain, and its activity is significantly reduced during wakefulness.
Poor glymphatic function has been linked to various brain diseases, including neurodegenerative disorders, traumatic brain injury, and stroke, suggesting it plays a crucial role in brain health and disease prevention.

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SUMMER TIME

@summerhasfun · X

The Glymphatic System – A Beginner's Guide - PMC https://t.co/dUy63W5NeY

Oct 11, 2025 · 68 followers View post →

Living Empowered®

@livingempowered · X

The Glymphatic System – A Beginner's Guide - PMC https://t.co/G966ESBhgk

Sep 21, 2025 · 671 followers View post →

nzc

@ngvrnd · X

@St_Rev https://t.co/6i5XKNpcbF

Jan 24, 2025 · 1 like · 1,022 followers View post →

con·sci·en·tious ob·jec·tor

@clevebarb · X

The Glymphatic System – A Beginner's Guide - PMC https://t.co/T3E0ogoHAe

Nov 27, 2024 · 1,711 followers View post →

diana flores

@dianaflores37 · X

RT @photobiogenesis: The Glymphatic System – A Beginner's Guide https://t.co/bdMDyhDbDz

Sep 20, 2024 · 4 shares · 346 followers View post →

Pattibe

@pattiber1 · X

The Glymphatic System – A Beginner's Guide - PMC https://t.co/DXKNOgEORn

Aug 17, 2024 · 773 followers View post →

Roanne Hurley

@interestinpsyc · X

RT @photobiogenesis: The Glymphatic System – A Beginner's Guide https://t.co/bdMDyhDbDz

Aug 13, 2024 · 4 shares · 16 followers View post →

PlanetOptimism

@planetoptimism · X

RT @photobiogenesis: The Glymphatic System – A Beginner's Guide https://t.co/bdMDyhDbDz

Aug 12, 2024 · 4 shares · 92 followers View post →

Bryce Hanna

@photobiogenesis · X

The Glymphatic System – A Beginner's Guide https://t.co/bdMDyhDbDz

Aug 12, 2024 · 23 likes · 4 shares · 34,223 followers View post →

Rebecca Hibbs

@RebeccaHibbs4 · X

The Glymphatic System – A Beginner's Guide - PMC https://t.co/iFkdf9tPDt

Jun 16, 2024 · 224 followers View post →

Clara Romera

@clararomenino · X

18/20

Jun 14, 2024 · 5 likes · 2,833 followers View post →

Raghav Agrawal @impactology@mastodon.social

@impactology.bsky.social · Bluesky

The Glymphatic System – A Beginner's Guide by Nadia Aalling Jessen, Anne Sofie Finmann Munk, Iben Lundgaard and Maiken Nedergaard www.ncbi.nlm.nih.gov/pmc/articles...

Mar 14, 2024 · 5 likes · 4 shares View post →

Raghav Agrawal @impactology@mastodon.social

@impactology.bsky.social · Bluesky

TIL about Glymphatic System (similar to lymphatic system but for clearing waste in central nervous system fluid — brain & spinal cord). Discovered in 2013. en.wikipedia.org/wiki/Glympha... www.ncbi.nlm.nih.gov/pmc/articles...

Mar 14, 2024 · 1 like · 4 shares View post →

Kameshwari-kate

@Kameshwarikate · X

https://t.co/6HoFSQNrye

Oct 5, 2023 · 319 followers View post →

getnurut

@getnurut · X

Fungsi dia adalah untuk membuang sisa protein, lipid, asid amino, neurotransmitter dsb melalui cecair otak yang dipanggil Cerebrospinal Fluid (CSF). The Glymphatic System – A Beginner's Guide https://t.co/MS0QfOxPLu.

Sep 22, 2023 · 1 like · 1,524 followers View post →

Montse

@msdc0502 · X

⚡️ https://t.co/1M1Mtk66pN

Jun 18, 2023 · 859 followers View post →

Tony Nikolic ⚖️ Corinthians 15:58- #Holdtheline™️

@TonyNikolic10 · X

RT @jathorpmfm: The Glymphatic System: A Beginner's Guide Nadia Aalling Jessen et al. Neurochem Res. 2015 Dec. Free PMC article The Glympha…

Apr 9, 2023 · 2 shares · 11,313 followers View post →

James Thorp MD

@jathorpmfm · X

The Glymphatic System: A Beginner's Guide Nadia Aalling Jessen et al. Neurochem Res. 2015 Dec. Free PMC article The Glymphatic System: A Beginner's Guide - PubMed https://t.co/V6zCHL91ko

Apr 9, 2023 · 8 likes · 2 shares · 84,776 followers View post →

Mates of the Alliance

@MatesofAlliance · X

RT @fifty262fifty: Free Sleep 101 Course. Learn about the biology of sleep along with some self-care tips. #sleep #selfcare #healthreliance…

Nov 21, 2022 · 1 share · 26,360 followers View post →

Living with Gadolinium, LLC

@Lambertdebb · X

Going back to this article https://t.co/i5a6jXykpw Gad enters the CSF. 'If' the glymphatic system fails unable to excrete the Gad - would it exasperate 'Inflammation' - damage to the mitochondria? Set off cytokine storms and ? Glymphatic ... Beginners... https://t.co/YUHAdMmZhV https://t.co/LohzX6X0OF

Nov 21, 2022 · 4 likes · 1,437 followers View post →

多情仏心

@jiangminjp · X

The Glymphatic System – A Beginner's Guide - PMC https://t.co/pfYLGMCmTO Glymphatic system - Wikipedia https://t.co/VrbnmUhKJp

Nov 12, 2022 · 1,757 followers View post →

Raghav Agrawal

@impactology · X

The Glymphatic System – A Beginner's Guide by Nadia Aalling Jessen, Anne Sofie Finmann Munk, Iben Lundgaard and Maiken Nedergaard https://t.co/2ST3a4AtQP

Nov 4, 2022 · 3,364 followers View post →

The Holistic Nomad

@ElyagEkalb · X

The Glymphatic System – A Beginner's Guide https://t.co/qo8K65ts9c

Oct 6, 2022 · 48 followers View post →

DwindleProof

@DwindleProof · X

@Rainmaker1973 CSF production occurs 24/7. The real nighttime washing comes through the glymphatic system. https://t.co/5qsMXRQhhM

Sep 10, 2022 · 13 likes · 298 followers View post →

Tara Tobias PT, DPT, NCS

@taramtobias · X

The glymphatic system is 1 mechanism of waste removal from the CNS and distribution of glucose, lipids, amino acids, and neurotransmitters. It is theorized that the glymphatic system is only active while sleeping. #healthyliving #sleephygiene https://t.co/hCsNNTGtEs

May 23, 2022 · 1 like · 654 followers View post →

Henry Watt

@Charlie_Dimmock · X

https://t.co/pFUocxMhyB

May 14, 2022 · 9,517 followers View post →

Henry Watt

@Charlie_Dimmock · X

RT @Charlie_Dimmock: @H2OhTwist https://t.co/pFUocxMhyB

Apr 28, 2022 · 2 shares · 9,517 followers View post →

karenk_____

@karenk_____ · X

RT @Charlie_Dimmock: @H2OhTwist https://t.co/pFUocxMhyB

Apr 27, 2022 · 2 shares · 901 followers View post →

Chris Pierce, ACMHC, NCC

@fifty262fifty · X

Free Sleep 101 Course. Learn about the biology of sleep along with some self-care tips. #sleep #selfcare #healthreliance Go to sleep https://t.co/ilA6r1vQ9T

Mar 16, 2022 · 3 likes · 1 share · 930 followers View post →

Fun Pop Extra

@FunPopExtra · X

The Glymphatic System: A Beginner's Guide - PubMed https://t.co/PCsIfJ8PFo

Mar 5, 2022 · 1 like · 744 followers View post →

Korak Sarkar MD MHDS FAAN

@koraksarkar_M3D · X

The #Glymphatic System – A Beginner's Guide https://t.co/SlOJd90LYw

Feb 6, 2022 · 2 likes · 658 followers View post →

Tom Truett

@truett_tom · X

@RottenInDenmark https://t.co/V3aAawzmjK

Dec 7, 2021 · 144 followers View post →

Junaid Ansari

@juneuromd · X

The Glymphatic System: A Beginner’s Guide | SpringerLink https://t.co/mtpz9gfKu9

Nov 28, 2021 · 8,449 followers View post →

FamilyCaregivers

@FamilyCarersAB · X

Why might sleep and sleep quality be important in preventing dementia? Have a look at some of the knowledge on the Glymphatic System https://t.co/5tnwQVdlTi https://t.co/vTsPcyJREA

Sep 8, 2021 · 1 like · 2,038 followers View post →

Chris Giza

@griz1 · X

Jul 7, 2021 · 5 likes · 4,915 followers View post →

中山晴雄　Haruo Nakayama

@haruwonakayame · X

RT @griz1: Just posting from our @BrainSPORT #JC back in May. Beginners Guide to #GlymphaticSystem! @UCLANsgy @uclachildneuro @UCLANeurolog…

Jun 30, 2021 · 2 shares · 521 followers View post →

Cirelle Rosenblatt

@drcirelle · X

RT @griz1: Just posting from our @BrainSPORT #JC back in May. Beginners Guide to #GlymphaticSystem! @UCLANsgy @uclachildneuro @UCLANeurolog…

Jun 29, 2021 · 2 shares · 129 followers View post →

Chris Giza

@griz1 · X

Jun 29, 2021 · 6 likes · 2 shares · 4,915 followers View post →

Deborah Huang MD MPH

@debhuang_md · X

@mpmesias @UWMedicine Glymphatic (name coined since glial cells involved w/lymphatic system) channel system helps drain CNS waste from brain. Very cool. https://t.co/EeNxmRyXti

May 14, 2021 · 2 likes · 293 followers View post →

Henry Watt

@Charlie_Dimmock · X

@H2OhTwist https://t.co/pFUocxMhyB

Mar 15, 2021 · 2 likes · 2 shares · 9,517 followers View post →

Kat Priddis

@kls_kat · X

@drashleyreece @KieranWalsh8 This was an incredible revelation to me: @TraumaMasters @gsmckenna

Mar 8, 2021 · 1 like · 1,439 followers View post →

Y David Zhu, PhD

@ydavidzhu · X

The Glymphatic [Glial + Lymphatic] System is having its moment. #neuroscience https://t.co/ENLGKnz1xb

Dec 10, 2020 · 1 like · 156 followers View post →

Pete Smith

@ProfPeteSmith · X

@paradoxfloss Yes @paradoxfloss - it is the glymphatic system. We are aware of it. Thnx @DrOliviaLesslar Glial cells are Important - maybe more so with lonstanding ME. We need quality sleep for good function of this system and ME/CFS does not provide refreshing sleep. https://t.co/4KML7I8hdJ

Sep 18, 2020 · 1,579 followers View post →

NUCCA Wellness Clinic of Chicago

@nuccawellness · X

What's really interesting about the #glymphatic system is that it functions mainly during sleep and is largely disengaged during awake. https://t.co/BV9lpAV06h

Sep 8, 2020 · 9 followers View post →

isral Duke

@isralduke · X

Your brain has a collection system which removes waster and distributes nutrients. It only works while you’re in deep sleep. Say hello to the glymphatic system. Sleep really does clear your head and make your better. https://t.co/wLjvSgiV5x

Sep 4, 2020 · 452 followers View post →

Martin Fischmeister

@ulfmm1 · X

Das ist einmal etwas ganz Neues ... https://t.co/EFRWlySd7P

Aug 15, 2020 · 16 followers View post →

Valentino

@Violentino84 · X

RT @drWilliamLordan: The Glymphatic System – A Beginner's Guide. A good read with nice graphics :: #brainhealth #CSF #glymphatic #DCCJP #C…

Feb 14, 2020 · 1 share · 24 followers View post →

Olive Complexion - one has, one hasn't! J'aime Li

@jasirgany · X

The Glymphatic System – A Beginner's Guide https://t.co/ZJtPATkz49

Feb 9, 2020 · 59 followers View post →

Patrice Lamoree

@alkahest · X

Your brain's "housekeeper" - The Glymphatic System: A Beginner's Guide. - PubMed - NCBI https://t.co/vxhFAssv0b

Dec 21, 2019 · 200 followers View post →

Tihana Gorenc

@Tihic57 · X

The Glymphatic System – A Beginner's Guide https://t.co/UpOqpPPS1N

Mar 24, 2019 · 66 followers View post →

Ziba

@ze1981 · X

The Glymphatic System – A Beginner's Guide https://t.co/lFgT8UKKZo

Mar 8, 2019 · 874 followers View post →

John Paul Catanzaro

@catanzarogroup · X

The Glymphatic System – A Beginner's Guide https://t.co/AbrGEzw56b

Feb 16, 2019 · 752 followers View post →

The Glymphatic System: A Beginner's Guide.

Mentions per month

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What people are saying

Abstract in brief

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