Am J Physiol Regul Integr Comp Physiol August 2015 PMID 26041108

Regular postexercise cooling enhances mitochondrial biogenesis through AMPK and p38 MAPK in human skeletal muscle.

Mohammed Ihsan, James F Markworth, Greig Watson, Hui Cheng Choo, Andrew Govus, Toan Pham, Anthony Hickey, David Cameron-Smith, Chris R Abbiss

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Mentions

16
Peak: 3 in Mar 2021
across 4 sources since Aug 2020

Extended reach

391,865
potential audience

Total likes

6,256

Video views

215,786

Mentions per month

Aug 2020 – Dec 2025

Where it's discussed

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  • Facebook1 posts

AI synopsis

What people are saying

Discussions reflect moderate engagement and curiosity, with comments debating the effectiveness of cold exposure before training and mentioning pathways like AMPK, while some posts share related health tips or strategies, using scientific terms and practical suggestions that highlight an interest in applying the research.

AgreementNeither agree nor disagree

The discussions show mixed opinions, with some skepticism about the mechanisms and application, indicating neither strong agreement nor disagreement.

InterestModerate interest

Most posts express curiosity or make related suggestions, suggesting moderate interest in mitochondrial biogenesis and exercise responses.

EngagementModerate engagement

Posts reference specific ideas like satellite cell theory and AMPK pathways, demonstrating some engagement with the scientific details.

ImpactModerate impact

The shared links and mentions of practical applications, like fat burning and weight loss, imply the discussions could influence personal health tactics but not widespread scientific change.

Abstract in brief

  • This study shows that regular cold water immersion after exercise can boost the body's mitochondrial biogenesis in skeletal muscle by activating key signaling pathways like AMPK and p38 MAPK, leading to improved endurance performance.
  • Cold water immersion increases the levels of certain proteins and enzymes related to mitochondrial function and energy production, suggesting enhanced muscle adaptation to training.
  • Despite some increases in mitochondrial activity markers, no significant changes were observed in all respiratory chain complexes, indicating that cold immersion mainly influences specific pathways involved in mitochondrial growth rather than overall complex protein content.

Top posts

Most liked on X and Bluesky
Nick Tiller, Ph.D.
@NBTiller · X

@LG7_luca @hubermanlab @JPhysiol Probably more favorable for endurance training via moderation of AMPk signaling pathways. https://t.co/xTzanslUuP

Sep 5, 2022 · 3 likes · 10,615 followers View post →
Sprint Science
@spikesonly · X

@JoseAntonioPhD @B_Holmer https://t.co/mi6riC3cmG I don’t think the satellite cell theory holds water if you do the cold before training. Also if you train multiple times a day the sequence doesn’t matter either.

Feb 8, 2024 · 1 like · 34,089 followers View post →
Beef Ent.
@BeefEnt · X

https://t.co/EPgrSml2oB

Aug 22, 2020 · 128,409 followers View post →
Traderpros
@Fensterputzer · X

7 Ways to Burn More Fat by Increasing Mitochondria https://t.co/sA6VxVnswP via @YouTube

Mar 28, 2021 · 2,904 followers View post →

All mentions

Sprint Science
@spikesonly · X

@JoseAntonioPhD @B_Holmer https://t.co/mi6riC3cmG I don’t think the satellite cell theory holds water if you do the cold before training. Also if you train multiple times a day the sequence doesn’t matter either.

Feb 8, 2024 · 1 like · 34,089 followers View post →
Nick Tiller, Ph.D.
@NBTiller · X

@LG7_luca @hubermanlab @JPhysiol Probably more favorable for endurance training via moderation of AMPk signaling pathways. https://t.co/xTzanslUuP

Sep 5, 2022 · 3 likes · 10,615 followers View post →
Traderpros
@Fensterputzer · X

7 Ways to Burn More Fat by Increasing Mitochondria https://t.co/sA6VxVnswP via @YouTube

Mar 28, 2021 · 2,904 followers View post →
David Thomas
@davidthomasweb · X

https://t.co/W6RDxWq9VX https://t.co/0jOeCjZW2U How A Metabolism Boosting Coffee Creamer Can Help You Achieve Weight Loss Goals? With more than 400 billion cups consumed every year, coffee has become th

Mar 26, 2021 · 3 followers View post →
Beef Ent.
@BeefEnt · X

https://t.co/EPgrSml2oB

Aug 22, 2020 · 128,409 followers View post →
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