Curr Biol August 2015 PMID 26166778

Modeling the 3D geometry of the cortical surface with genetic ancestry.

Chun Chieh Fan, Hauke Bartsch, Andrew J Schork, Chi-Hua Chen, Yunpeng Wang, Min-Tzu Lo, Timothy T Brown, Joshua M Kuperman, Donald J Hagler, Nicholas J Schork, Terry L Jernigan, Anders M Dale

Mentions

66
Peak: 4 in Jun 2023
across 7 sources since Jul 2015

Extended reach

118,738
potential audience

Total likes

1,421

Video views

28,770

Mentions per month

Jul 2015 – May 2025

Where it's discussed

  • X / Twitter25 posts
  • Blogs14 articles
  • Reddit10 posts
  • Facebook9 posts
  • YouTube4 videos
  • News3 articles
  • Bluesky1 posts

AI synopsis

What people are saying

Discussions reflect a strong curiosity about how brain morphology reveals genetic backgrounds, with posts praising the study's innovative use of 3D cortical modeling and its implications for neuroscience and anthropology. The tone varies from academic appreciation to cautious skepticism about broader applications, demonstrating high engagement and interest in the topic's scientific and societal relevance.

AgreementModerate agreement

Most discussions acknowledge the significance of the study, emphasizing how brain shape can predict genetic ancestry and confirming prior research in neuroanatomy.

InterestHigh interest

The topic of brain shape variations and their relation to genetics appears highly intriguing to the community, with many posts emphasizing its novelty and potential implications.

EngagementHigh engagement

Participants delve into the details, referencing specific findings like cortical geometry predicting ancestry, and some even speculate on fine-grained applications, showing deep involvement.

ImpactModerate impact

While some posts highlight the research's potential to influence understanding of human evolution and reduce biases, others touch on controversies or ethical considerations, indicating a moderate perceived societal impact.

Abstract in brief

  • The study explores how the 3D shape of the brain's surface reflects genetic ancestry across different populations, such as West Africa, Europe, East Asia, and America, showing that cortical surface geometry can predict ancestry even amidst complex migration and mixing events.
  • Unlike traditional methods that rely on skull measurements, this research suggests that the detailed surface folds and shapes of the brain hold more specific information about our genetic background.
  • The findings highlight that brain shape variations linked to ancestry go beyond overall brain size, offering insights into regional brain folding patterns associated with different ancestral lineages, which can improve understanding of human evolution and reduce biases in brain research.]

Top posts

Most liked on X and Bluesky
steve hsu
@hsu_steve · X

Related PING (Pediatric Imaging, Neurocognition, and Genetics) study: ML-classifier detects ancestry based on differences in brain morphology. Modeling the 3D Geometry of the Cortical Surface with Genetic Ancestry Cell https://t.co/uJ58AG6gTG https://t.co/6CJf7GcIao https://t.co/len4wyHXyF

Jun 1, 2023 · 21 likes · 4 shares · 40,190 followers View post →
Cody Moser
@LTF_01 · X

This is absolutely crazy: Modeling the 3D Geometry of the Cortical Surface with Genetic Ancestry. Reminds me of some work by Algee-Hewitt. I wonder how fine-grained you can push this. https://t.co/VAzVFKu11Q https://t.co/OF4HSYek2Z

Apr 15, 2019 · 5 likes · 1 share · 8,198 followers View post →
Holtz
@Biorealism · X

@gcochran99 @blurypie @wyqtor @dwarkesh_sp There have presumably have been some changes over that period as 3D geometry of cortical surface is highly predictive of continental ancestry. https://t.co/KOCcpfxXBT

May 18, 2025 · 3 likes · 1 share · 8,913 followers View post →
Shiro Ishii Jr
@HirohitoTopGuy · X

Diferentes populações humanas mostram variações significativas em estruturas cranianas e cerebrais, reforçando a existência de diferenças biológicas associadas às raças https://t.co/x5Ibx7BUVl

Feb 8, 2025 · 2 likes · 268 followers View post →
FS4420
@FS4420 · X

@JesseKellyDC "human cortical surface robustly predicts an individual’s genetic ancestry" https://t.co/66vt1sQJsb

Jun 3, 2022 · 2 likes · 140 followers View post →
Jewish Guy
@Scorchard14 · X

@eee_electrical @obitosama88 @Kdubtru No you fuckong wont you lying sack of

Dec 23, 2024 · 1 like · 1 share · 803 followers View post →

All mentions

DeimosEidt
@DeimosEidt · X

@Magnus_O_Vermei @happyeleph73600 @roniblackkk E essas já consideram, fenotipicamente, raças diferentes: Diferentes populações humanas mostram variações significativas em estruturas cranianas e cerebrais, reforçando a existência de diferenças biológicas associadas às raças https://t.co/JWmhdW1WkA

May 26, 2025 · 103 followers View post →
Mike Kimel
@MikeKimel · X

RT @Biorealism: @gcochran99 @blurypie @wyqtor @dwarkesh_sp There have presumably have been some changes over that period as 3D geometry of…

May 19, 2025 · 1 share · 282 followers View post →
Holtz
@Biorealism · X

@gcochran99 @blurypie @wyqtor @dwarkesh_sp There have presumably have been some changes over that period as 3D geometry of cortical surface is highly predictive of continental ancestry. https://t.co/KOCcpfxXBT

May 18, 2025 · 3 likes · 1 share · 8,913 followers View post →
Felipe Alvarez de León
@Gorfer47 · X

La neuroanatomía muestra variaciones raciales más allá del tamaño absoluto del cerebro. Los estudios indican que la forma del cerebro puede predecir la ascendencia racial con gran precisión https://t.co/fJqvw63OCM

Apr 23, 2025 · 1 like · 21 followers View post →
DeimosEidt
@DeimosEidt · X

@luca_saldanha10 @iluvhellkitty @Guilherme933689 @BocchiAgiota2 @grok Em um estudo com mais de 27.000 recém-nascidos, brancos e hispânicos tinham circunferência craniana 0,4 cm maior que a de negros, e essa diferença aumentava conforme a idade gestacional https://t.co/JWmhdW1WkA https://t.co/GeqKaLtKMb

Apr 18, 2025 · 103 followers View post →
Shiro Ishii Jr
@HirohitoTopGuy · X

Diferentes populações humanas mostram variações significativas em estruturas cranianas e cerebrais, reforçando a existência de diferenças biológicas associadas às raças https://t.co/x5Ibx7BUVl

Feb 20, 2025 · 268 followers View post →
Shiro Ishii Jr
@HirohitoTopGuy · X

A neuroanatomia apresenta variações raciais além do tamanho absoluto do cérebro. Estudos indicam que a forma cerebral pode prever ancestralidade racial com alta precisão https://t.co/x5Ibx7BUVl

Feb 20, 2025 · 268 followers View post →
Shiro Ishii Jr
@HirohitoTopGuy · X

Diferentes populações humanas mostram variações significativas em estruturas cranianas e cerebrais, reforçando a existência de diferenças biológicas associadas às raças https://t.co/x5Ibx7BUVl

Feb 8, 2025 · 2 likes · 268 followers View post →
Shiro Ishii Jr
@HirohitoTopGuy · X

A neuroanatomia apresenta variações raciais além do tamanho absoluto do cérebro. Estudos indicam que a forma cerebral pode prever ancestralidade racial com alta precisão https://t.co/x5Ibx7BUVl

Feb 4, 2025 · 1 like · 268 followers View post →
Jewish Guy
@Scorchard14 · X

RT @Scorchard14: @eee_electrical @obitosama88 @Kdubtru No you fuckong wont you lying sack of

Dec 23, 2024 · 1 share · 803 followers View post →
Jewish Guy
@Scorchard14 · X

@eee_electrical @obitosama88 @Kdubtru No you fuckong wont you lying sack of

Dec 23, 2024 · 1 like · 1 share · 803 followers View post →
christopher
@chobo641 · X

@circe_acapella @bryandoganoff @dufrianord You mean brain shape? https://t.co/LwEY1PtZjv https://t.co/PnLs8gfLN8

Feb 4, 2024 · 1 like · 32 followers View post →
Darwin la Vengeance
@Darwinvsle15823 · X

@lesgalapagos @EL_PalpitoS @TaRkOTheSparrow @Calnos1 @lavoixdeportici @Psyhodelikus @_Olrik_ 1) Sur les races. Prédiction de l’ascendance génétique des Africains, des Européens et des Asiatiques à partir de la géométrie tridimensionnelle de la surface corticale. Oui, la race n’est pas « que » la couleur de peau. https://t.co/xAkDQMrP9g

Aug 30, 2023 · 28 followers View post →
hbd chick
@hbdchick · X

RT @hsu_steve: Related PING (Pediatric Imaging, Neurocognition, and Genetics) study: ML-classifier detects ancestry based on differences in…

Jun 5, 2023 · 4 shares · 15,696 followers View post →
JayMan
@JayMan471 · X

RT @hsu_steve: Related PING (Pediatric Imaging, Neurocognition, and Genetics) study: ML-classifier detects ancestry based on differences in…

Jun 1, 2023 · 4 shares · 9,238 followers View post →
Falsifier
@PrefFalsifier · X

RT @hsu_steve: Related PING (Pediatric Imaging, Neurocognition, and Genetics) study: ML-classifier detects ancestry based on differences in…

Jun 1, 2023 · 4 shares · 835 followers View post →
steve hsu
@hsu_steve · X

Related PING (Pediatric Imaging, Neurocognition, and Genetics) study: ML-classifier detects ancestry based on differences in brain morphology. Modeling the 3D Geometry of the Cortical Surface with Genetic Ancestry Cell https://t.co/uJ58AG6gTG https://t.co/6CJf7GcIao https://t.co/len4wyHXyF

Jun 1, 2023 · 21 likes · 4 shares · 40,190 followers View post →
FS4420
@FS4420 · X

@JesseKellyDC "human cortical surface robustly predicts an individual’s genetic ancestry" https://t.co/66vt1sQJsb

Jun 3, 2022 · 2 likes · 140 followers View post →
Michael inTheCityPgh
@MichaelPghPA · X

RT @EpektasisJohn: @JesseKellyDC It is factually untrue that average IQ does not vary across races or by pigmentation. There's no real dis…

Jun 3, 2022 · 1 share · 850 followers View post →
Headless Box
@headless_box · X

Modeling the 3D Geometry of the Cortical Surface With Genetic Ancestry - https://t.co/9YVegzAyQH

Nov 11, 2021 · 99 followers View post →
Elephant_Frog
@elephant_ben · X

@tonygill3 @itsbirdemic Also, controversy probably isn't the reason that people refused to touch his work. There was an article published detailing brain differences between those of different ancestries in Current biology. https://t.co/4hPsp65rCC More likely, it is because his work is awful.

Aug 7, 2020 · 1 like · 766 followers View post →
Lycurguien
@MonsieurMartin3 · X

@Monolecte @Uneheuredepeine Par exemple, on peut remonter à la race d'une personne seulement à partir son IRM https://t.co/GkpXUWGcrR https://t.co/szjqyRrbIC https://t.co/h7pVnhDL5j

Jun 24, 2019 · 737 followers View post →
Bottlenecked_Y
@Bottlenecked_Y · X

RT @LTF_01: This is absolutely crazy: Modeling the 3D Geometry of the Cortical Surface with Genetic Ancestry. Reminds me of some work by Al…

Apr 15, 2019 · 1 share · 276 followers View post →
Cody Moser
@LTF_01 · X

This is absolutely crazy: Modeling the 3D Geometry of the Cortical Surface with Genetic Ancestry. Reminds me of some work by Algee-Hewitt. I wonder how fine-grained you can push this. https://t.co/VAzVFKu11Q https://t.co/OF4HSYek2Z

Apr 15, 2019 · 5 likes · 1 share · 8,198 followers View post →
Lycurguien
@MonsieurMartin3 · X

@Thomas41670729 @dr_l_alexandre Les différences cérébrales sont également établies https://t.co/GkpXUWGcrR https://t.co/szjqyRrbIC https://t.co/4Z9OfPXEfq

Mar 31, 2019 · 737 followers View post →
Paleogenomics - María Ávila Arcos
@paleogenomics.bsky.social · Bluesky

Modeling the 3D Geometry of the Cortical Surface with Genetic Ancestry http://www.sciencedirect.com/science/article/pii/S0960982215006715

Jul 16, 2015 View post →