Caffeine has a circadian effect in organisms from humans to funghi. In contrast to humans, where it works on the clock via cAMP (https://t.co/6Ok5rXgCJD), @lflarrondo shows that caffeine affects the #fungalclock independently of PDE-cAMP-PKA signaling: https://t.co/eBInJsfZSw
Effects of caffeine on the human circadian clock in vivo and in vitro.
Mentions
Extended reach
Total likes
Video views
Mentions per month
Aug 2021 – Nov 2024Where it's discussed
-
News134 articles
-
X / Twitter25 posts
-
Facebook23 posts
-
Blogs21 articles
-
YouTube8 videos
-
Reddit2 posts
AI synopsis
What people are saying
Several social discussions highlight the scientific importance of the article, discussing caffeine's delay of melatonin rhythms and its cellular effects, with language emphasizing its relevance and potential impact, such as describing the research as 'scientific' or 'breaking new ground.' This choice of words indicates a strong appreciation of the study's significance and a high level of engagement with its findings.
Most discussions and social discussions support the findings of the publication, emphasizing caffeine's role in delaying circadian rhythms and its biological mechanisms.
The posts demonstrate high interest, with many referencing the research's implications, such as caffeine's effect on sleep and wakefulness, and exploring scientific mechanisms.
The discussions include technical details, such as mechanisms involving adenosine receptors and cyclic AMP, indicating active and thoughtful engagement.
Users recognize the publication's significance, with some describing caffeine's effects as influential or potentially game-changing for understanding sleep regulation.
Abstract in brief
- Caffeine consumption in the evening can delay the human circadian melatonin rhythm by about 40 minutes, which is nearly half the delay caused by exposure to bright light at night.
- In laboratory experiments with cells, caffeine was found to lengthen the internal biological clock cycles through mechanisms involving adenosine receptors and cyclic AMP, a signaling molecule.
- Overall, caffeine influences human circadian timing by affecting core cellular clock components, explaining how this widely consumed drug impacts sleep and alertness regulation.]
Top posts
Most liked on X and Bluesky@prmshra 100%. In humans, looks like caffeine acts on serpentine adenosine receptors, binding competitively with adenosine and, as an inverse agonist, causing excitatory signaling to promote wakefulness. Not sure what this means for optimal use, though. https://t.co/gkYF0RWCS9
寝る前のカフェインとブルーライトで体内時計は狂いまくります。 とのこと・ 今コーヒー飲みながらパソコンでツイートしてます。 私からは以上です。 https://t.co/uqJewI2sjS
カフェインはアデノシン受容体シグナルを介して時計さん®︎の周期を延長する 朝飲むのはどうなんすか https://t.co/XZgOQb5gt1
参考: https://t.co/e3hqB9ZHOz
All mentions
Analyzing the Impact of Caffeine on Sleep Disruption at Different Intervals
This video explores how consuming 400 mg of caffeine at 0, 3, and 6 hours before sleep significantly disrupts sleep quality, supporting guidelines to avoid caffeine at least 6 hours prior to bedtime for optimal rest.
Impact of Caffeine on Human Circadian Rhythm and Cellular Clocks
Caffeine consumption in the evening can delay the human circadian melatonin rhythm by about 40 minutes. Laboratory experiments show caffeine lengthens biological clock cycles through interactions with cellular…
Impact of Caffeine on Human Circadian Rhythms and Sleep Regulation
Caffeine consumption in the evening can delay the human circadian melatonin rhythm by about 40 minutes, affecting sleep and alertness. The effects involve adenosine receptors and cyclic AMP, influencing cellular clock…
Caffeine's Impact on Mental and Brain Health: Benefits and Risks
Small doses of caffeine (0, 50, 150, and 450 mg) produce stimulant effects such as increased alertness, blood pressure, and positive mood in light, nondependent users. It enhances attention but may impair short-term…
Caffeine Metabolism: Genetic and Lifestyle Influences Explained
The study examined how genetic factors related to the CYP1A2 enzyme, along with other factors like sex, age, oral contraceptive use, and smoking status, influence the variability in caffeine metabolism within…
Impact of Caffeine Timing on Sleep Quality and Disruption
This video examines how consuming 400 mg of caffeine at 0, 3, and 6 hours before bed significantly disrupts sleep, emphasizing the importance of avoiding caffeine at least 6 hours prior to sleep for better sleep quality.
Health Benefits of Coffee and Caffeine Explained
Does coffee make you fit and awake? This video discusses the health benefits of coffee, including its rich antioxidant content and connection to improved brain function. We explore caffeine's effects, withdrawal…
Impact of Caffeine on Human Circadian Rhythms and Sleep Regulation
This video discusses how caffeine consumption, especially in the evening, delays the human circadian melatonin rhythm by nearly 40 minutes and affects cellular clock mechanisms, influencing sleep and alertness…
Publications for your reference: 1. Tina M. Burke et al. ,Effects of caffeine on the human circadian clock in vivo and in vitro.Sci. Transl. Med.7,305ra146-305ra146(2015).DOI:10.1126/scitranslmed.aac5125
https://t.co/URP7w6lb2H
参考: https://t.co/e3hqB9ZHOz
Ciemna strona kawy. Badania naukowe. https://t.co/2OSrMy7MOI przez @YouTube
RT @ayushnoori: @prmshra 100%. In humans, looks like caffeine acts on serpentine adenosine receptors, binding competitively with adenosine…
RT @ayushnoori: @prmshra 100%. In humans, looks like caffeine acts on serpentine adenosine receptors, binding competitively with adenosine…
@prmshra 100%. In humans, looks like caffeine acts on serpentine adenosine receptors, binding competitively with adenosine and, as an inverse agonist, causing excitatory signaling to promote wakefulness. Not sure what this means for optimal use, though. https://t.co/gkYF0RWCS9
Ciemna strona kawy. Badania naukowe. https://t.co/5dEkKZSnee przez @YouTube
寝る前のカフェインとブルーライトで体内時計は狂いまくります。 とのこと・ 今コーヒー飲みながらパソコンでツイートしてます。 私からは以上です。 https://t.co/uqJewI2sjS
RT @SRBR_Outreach: Caffeine has a circadian effect in organisms from humans to funghi. In contrast to humans, where it works on the clock v…
RT @SRBR_Outreach: Caffeine has a circadian effect in organisms from humans to funghi. In contrast to humans, where it works on the clock v…
RT @SRBR_Outreach: Caffeine has a circadian effect in organisms from humans to funghi. In contrast to humans, where it works on the clock v…
Caffeine has a circadian effect in organisms from humans to funghi. In contrast to humans, where it works on the clock via cAMP (https://t.co/6Ok5rXgCJD), @lflarrondo shows that caffeine affects the #fungalclock independently of PDE-cAMP-PKA signaling: https://t.co/eBInJsfZSw
Ciemna strona kawy. Badania naukowe. https://t.co/2hIDhYDpdD przez @YouTube
@Forrest__Gum Burke, T. M., Markwald, R. R., McHill, A. W., Chinoy, E. D., Snider, J. A., Bessman, S. C., Jung, C. M., O'Neill, J. S., & Wright, Effects of caffeine on the human circadian clock in vivo and in vitro. Science translational medicine, 7(305), 305ra146. https://t.co/InQI16po5X
Dietitian Tries Bella Hadid’s Model Diet to Stay Lean (HUGE ALMOND MOM F... https://t.co/4GQ5NxgqcJ via @YouTube
Tina M Burke et al. Sci Transl Med. 2015 Effects of caffeine on the human circadian clock in vivo and in vitro
Dietitian Tries Bella Hadid’s Model Diet to Stay Lean (HUGE ALMOND MOM F... https://t.co/4GQ5NxgqcJ via @YouTube
@srsimsr @Marluxia_asm pior q nem é mito https://t.co/Z8wqefUYm3 https://t.co/bXNBAOTGYI
Effects of & use of caffeine in sync with the human circadian clock https://t.co/wH8yuvihJH
@sleeplover16 @michaelgrandner @SleepAndSports @sleepdiplomat @sleepscientist @drcolleencarney Here's a paper showing caffeine delays circadian rhythms (CR) if consumed @ night. Would extrapolate (needs further work) that for AM use it would advance CR =good. Seems caffeine makes you more sensitive to light. Maybe not bad to drink ☕️ in early AM. https://t.co/AMvRIFf9nm
@haidut haidut, love your work; what do you think of caffeine buildup delaying one's circadian rhythms --> drop in sleep quality? https://t.co/VgTuPeOKmN, peat argues that caffeine before bed can improve sleep by lowering estrogen and boosting metabolism
カフェインはアデノシン受容体シグナルを介して時計さん®︎の周期を延長する 朝飲むのはどうなんすか https://t.co/XZgOQb5gt1
Продавцы КОФЕ об этом молчат! Как кофеин влияет на наш ферритин, кальций, железо, кортизол https://t.co/V83wysOYbm через @YouTube
歌万