November 2015 PMID 26378978

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes.

Bernard Zinman, Christoph Wanner, John M Lachin, David Fitchett, Erich Bluhmki, Stefan Hantel, Michaela Mattheus, Theresa Devins, Odd Erik Johansen, Hans J Woerle, Uli C Broedl, Silvio E Inzucchi

Mentions

281
Peak: 21 in Aug 2020
across 7 sources since Sep 2015

Extended reach

1,257,934
potential audience

Total likes

1,735

Video views

36,644

Mentions per month

Sep 2015 – Nov 2025

Where it's discussed

  • X / Twitter131 posts
  • News76 articles
  • Facebook42 posts
  • Blogs23 articles
  • YouTube5 videos
  • Bluesky2 posts
  • Reddit2 posts

AI synopsis

What people are saying

In these discussions, participants often cite the substantial mortality reduction associated with empagliflozin, such as a 32% decrease in death from cardiovascular causes and a 15% reduction in all-cause mortality. Phrases like 'paradigm shifting' and 'setting the bar for new diabetes drugs' reflect the excitement and serious consideration these findings demand. The tone is predominantly optimistic, with a mix of healthy skepticism regarding study funding, showing a deep engagement with the material by discussing both potential benefits and complications.

AgreementModerate agreement

Most discussions show a broad support for the conclusions of the publication, with some nuanced skepticism regarding the funding sources.

InterestHigh interest

The discussions indicate high curiosity about empagliflozin and its implications for cardiovascular health and diabetes management.

EngagementModerate engagement

Participants often reference specific studies, highlight key statistics, and discuss clinical implications, indicating a moderate level of engagement.

ImpactHigh impact

Many participants perceive the findings as highly significant, particularly in how they may influence future treatment protocols.

Abstract in brief

  • Empagliflozin, a medication for type 2 diabetes, was tested to see how it impacts cardiovascular health and mortality when added to standard care for high-risk patients.
  • In a study of 7,020 patients, empagliflozin led to a significant reduction in death from cardiovascular causes and overall mortality compared to a placebo, although myocardial infarction and stroke rates were similar between both groups.
  • While participants taking empagliflozin experienced higher rates of genital infections, the overall safety profile was comparable to those on placebo, highlighting its benefits for cardiovascular outcomes in high-risk diabetic patients.

Top posts

Most liked on X and Bluesky
د.عبدالرحمن جوهرجي
@drjoharji1 · X

مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في منع الجلطات توجد عدة ادوية منها جارديانس متوفر في #وصفتي وجدت دراسة empa reg انه يقلل وفيات القلب بنسبة ٣٨٪وجلطات القلب١٣٪ https://t.co/TC5nV7J68s https://t.co/AjBinTTySF

Aug 25, 2022 · 100 likes · 21 shares · 88,804 followers View post →
DiscoStew
@DiscoStew66 · X

If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.co/CpJfIdLO9c

Aug 29, 2020 · 68 likes · 20 shares · 10,795 followers View post →
Matthew Sparks, MD
@Nephro_Sparks · X

Dr. Braunwald points out the the EMPA-REG trial was one of the most impactful clinical trials performed. Was a safety trial and actually showed benefit SGLT2i now considered the statins of the 21st century Remarkable Braunwald is a #flozinator https://t.co/E3lGFseGHc https://t.co/6xTbRHiMfD

Oct 14, 2021 · 66 likes · 18 shares · 21,182 followers View post →
S
@SsJankauskas · X

I’ll bet the first anti-aging drug will be an SGLT2 inhibitor. 1️⃣ Look at results of the EMPA-REG OUTCOME trial (https://t.co/osz618oJB0 ) In this study SGLT2i reduced mortality of patients with Type 2 Diabetes. But look closely. The drug was ineffective in patients younger than https://t.co/YpilwMyNiH https://t.co/SLBLIbFMR3

Jun 6, 2024 · 43 likes · 9 shares · 1,560 followers View post →
Endocrine dialogues
@EndoDialogues · X

2015: EMPA-REG surprise! The trial was designed to test empagliflozin non-inferiority for CV outcomes in pts with T2DM and high CV risk. Result: empagliflozin was superior to placebo and reduced several MACE, including death from any cause. https://t.co/6VIrn3NksE 9/20

Oct 29, 2022 · 41 likes · 1 share · 6,465 followers View post →
ACCP Cardiology PRN
@accpcardprn · X

"It's almost embarrassing to be this desirable"

Dec 7, 2023 · 38 likes · 5 shares · 9,304 followers View post →

All mentions

Ken Milne MD
@TheSGEM · X

@MichaelEvanson1 @_APWK_ This was an industry-funded RCT. Because it was pharma-funded, does it automatically invalidate the results? I agree it should make us more skeptical, but disagree that it automatically invalidates results. https://t.co/PYjXWEG2oI

Apr 5, 2025 · 28,337 followers View post →
JorgeEdoChava75
@QicenoJorge · X

RT @DrDerekConnolly: @ncurzen That’s why our secondary prevention clinic is so important Nick I’m constantly prescribing evidence based th…

Jul 17, 2024 · 4 shares · 1,002 followers View post →
Warkaa
@warkaa21 · X

RT @DrDerekConnolly: @ncurzen That’s why our secondary prevention clinic is so important Nick I’m constantly prescribing evidence based th…

Jul 17, 2024 · 4 shares · 543 followers View post →
Vinoda Sharma #WIC
@vinoda_sharma · X

RT @DrDerekConnolly: @ncurzen That’s why our secondary prevention clinic is so important Nick I’m constantly prescribing evidence based th…

Jul 17, 2024 · 4 shares · 1,141 followers View post →
Huma Naqvi (on blue sky too)
@doc_hnaqvi · X

RT @DrDerekConnolly: @ncurzen That’s why our secondary prevention clinic is so important Nick I’m constantly prescribing evidence based th…

Jul 14, 2024 · 4 shares · 2,483 followers View post →
Prof Derek Connolly
@DrDerekConnolly · X

@ncurzen That’s why our secondary prevention clinic is so important Nick I’m constantly prescribing evidence based therapies for patients with diabetes. Everyone who made entry criteria for the SGLT2i trials receives one 32% ⬇️ in death @vinoda_sharma https://t.co/r9NwmyMXvV

Jul 14, 2024 · 16 likes · 4 shares · 3,937 followers View post →
Brian
@yep_its_brian1 · X

RT @SsJankauskas: I’ll bet the first anti-aging drug will be an SGLT2 inhibitor. 1️⃣ Look at results of the EMPA-REG OUTCOME trial (https:…

Jun 7, 2024 · 9 shares · 282 followers View post →
Eric
@ericsophia12 · X

RT @SsJankauskas: I’ll bet the first anti-aging drug will be an SGLT2 inhibitor. 1️⃣ Look at results of the EMPA-REG OUTCOME trial (https:…

Jun 7, 2024 · 9 shares · 90 followers View post →
Vince Beltran, Ph.D.
@levin_beltran · X

RT @SsJankauskas: I’ll bet the first anti-aging drug will be an SGLT2 inhibitor. 1️⃣ Look at results of the EMPA-REG OUTCOME trial (https:…

Jun 6, 2024 · 9 shares · 11,733 followers View post →
priya joseph
@ayirpelle · X

RT @SsJankauskas: I’ll bet the first anti-aging drug will be an SGLT2 inhibitor. 1️⃣ Look at results of the EMPA-REG OUTCOME trial (https:…

Jun 6, 2024 · 9 shares · 4,973 followers View post →
Manoj Mayogi Mishra
@mayogisense · X

RT @SsJankauskas: I’ll bet the first anti-aging drug will be an SGLT2 inhibitor. 1️⃣ Look at results of the EMPA-REG OUTCOME trial (https:…

Jun 6, 2024 · 9 shares · 574 followers View post →
John Greene
@Greene_Thoughts · X

RT @SsJankauskas: I’ll bet the first anti-aging drug will be an SGLT2 inhibitor. 1️⃣ Look at results of the EMPA-REG OUTCOME trial (https:…

Jun 6, 2024 · 9 shares · 1,710 followers View post →
Rizki
@rizrasmin · X

RT @SsJankauskas: I’ll bet the first anti-aging drug will be an SGLT2 inhibitor. 1️⃣ Look at results of the EMPA-REG OUTCOME trial (https:…

Jun 6, 2024 · 9 shares · 27 followers View post →
Dr Murphy WeightLoss
@TakeWeightOffMD · X

RT @SsJankauskas: I’ll bet the first anti-aging drug will be an SGLT2 inhibitor. 1️⃣ Look at results of the EMPA-REG OUTCOME trial (https:…

Jun 6, 2024 · 9 shares · 6,893 followers View post →
Hao Yin
@HaoYin20 · X

RT @SsJankauskas: I’ll bet the first anti-aging drug will be an SGLT2 inhibitor. 1️⃣ Look at results of the EMPA-REG OUTCOME trial (https:…

Jun 6, 2024 · 9 shares · 12,425 followers View post →
S
@SsJankauskas · X

I’ll bet the first anti-aging drug will be an SGLT2 inhibitor. 1️⃣ Look at results of the EMPA-REG OUTCOME trial (https://t.co/osz618oJB0 ) In this study SGLT2i reduced mortality of patients with Type 2 Diabetes. But look closely. The drug was ineffective in patients younger than https://t.co/YpilwMyNiH https://t.co/SLBLIbFMR3

Jun 6, 2024 · 43 likes · 9 shares · 1,560 followers View post →
S
@SsJankauskas · X

I’ll bet the first anti-aging drug will be an SGLT2 inhibitor. 1️⃣ Look at results of the EMPA-REG OUTCOME trial (https://t.co/osz618oJB0 ) In this study SGLT2i reduced mortality of patients with Type 2 Diabetes. But look closely. The drug was ineffective in patients younger than https://t.co/pAO5AEktp9 https://t.co/SLBLIbFMR3

Jun 6, 2024 · 1,560 followers View post →
Syed Shahrul Naz
@drshahrul80 · X

RT @EndoDialogues: 2015: EMPA-REG surprise! The trial aimed to test the non-inferiority of empagliflozin for CV outcomes in pts with T2D…

Jun 5, 2024 · 1 share · 6,925 followers View post →
Endocrine dialogues
@EndoDialogues · X

2015: EMPA-REG surprise! The trial aimed to test the non-inferiority of empagliflozin for CV outcomes in pts with T2DM and high CV risk. Result: empagliflozin was superior to placebo and reduced several MACE, including death from any cause. https://t.co/6VIrn3NksE

Jun 4, 2024 · 9 likes · 1 share · 6,465 followers View post →
miseitadameyo
@xtestarossa · X

RT @K212462681: SGLT2阻害薬(飢餓状態模倣)で寿命伸びる系の話はメタボ炎症予防でよく知られていて栄養指導でも話題に上る。 SGLT2阻害によりAMPK 活性化剤のAICAR が増加し老化細胞除去効果を発揮。AMPKは、肥満に伴って増加したPD-L1⁺老化細胞…

May 30, 2024 · 1 share · 12,419 followers View post →
O S
@s_wdy73012 · X

RT @drjoharji1: مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في من…

Jan 18, 2024 · 21 shares · 117 followers View post →
七夕
@K212462681 · X

SGLT2阻害薬(飢餓状態模倣)で寿命伸びる系の話はメタボ炎症予防でよく知られていて栄養指導でも話題に上る。 SGLT2阻害によりAMPK 活性化剤のAICAR が増加し老化細胞除去効果を発揮。AMPKは、肥満に伴って増加したPD-L1⁺老化細胞(Sero -Anergyに関与)も除去する。 https://t.co/W72lRR40tw https://t.co/i9sj93v3Ex

Dec 25, 2023 · 2 likes · 1 share · 258 followers View post →
Shelby Gross, PharmD, BCPS, AAHIVP
@shelbactam · X

RT @accpcardprn: "It's almost embarrassing to be this desirable"

Dec 8, 2023 · 5 shares · 378 followers View post →
Zack
@z4ksb3 · X

RT @accpcardprn: "It's almost embarrassing to be this desirable"

Dec 7, 2023 · 5 shares · 7 followers View post →
Brent C. Beckner PharmD, BCPS, BCCCP
@BCB_PharmD · X

RT @accpcardprn: "It's almost embarrassing to be this desirable"

Dec 7, 2023 · 5 shares · 849 followers View post →
Shan Wang, BS., PharmD., BCCCP, BCPS, FCCM
@shanwangsicurx · X

RT @accpcardprn: "It's almost embarrassing to be this desirable"

Dec 7, 2023 · 5 shares · 386 followers View post →
Kaitlyn Nichols, PharmD
@kaitlynjnichols · X

RT @accpcardprn: "It's almost embarrassing to be this desirable"

Dec 7, 2023 · 5 shares · 1 followers View post →
ACCP Cardiology PRN
@accpcardprn · X

"It's almost embarrassing to be this desirable"

Dec 7, 2023 · 38 likes · 5 shares · 9,304 followers View post →
RPhHiMA
@RPhHiMA · X

RT @drjoharji1: مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في من…

Oct 19, 2023 · 21 shares · 529 followers View post →
فيصل
@v999_x11 · X

RT @drjoharji1: مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في من…

Oct 19, 2023 · 21 shares · 239 followers View post →
Bashar Alnajada
@B_pharm · X

RT @drjoharji1: مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في من…

Oct 19, 2023 · 21 shares · 657 followers View post →
د.عبدالرحمن جوهرجي
@drjoharji1 · X

RT @drjoharji1: مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في من…

Oct 19, 2023 · 21 shares · 88,804 followers View post →
Colleen
@Colleen_Q3537 · X

RT @AAlMohammad87: The strong onset of #SGLT2i story in #CV medicine was in 2015 with #EMPA_REG trial @NEJM @BSHeartFailure @markcpetrie20…

Sep 5, 2023 · 2 shares · 30 followers View post →
Ahmed Dakshi
@AhmedDakshi · X

RT @AAlMohammad87: The strong onset of #SGLT2i story in #CV medicine was in 2015 with #EMPA_REG trial @NEJM @BSHeartFailure @markcpetrie20…

Aug 30, 2023 · 2 shares · 60 followers View post →
Abdallah Al-Mohammad
@AAlMohammad87 · X

The strong onset of #SGLT2i story in #CV medicine was in 2015 with #EMPA_REG trial @NEJM @BSHeartFailure @markcpetrie20 #CardioTwitter https://t.co/jIdFDcyvls

Aug 30, 2023 · 2 likes · 2 shares · 924 followers View post →
Dr Perry V Mayer
@drpvmayer · X

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes — NEJM https://t.co/C5Onu04RNZ

Apr 28, 2023 · 406 followers View post →
د.عبدالرحمن جوهرجي
@drjoharji1 · X

@Fahad90172146 بناء على دراسات علمية اهمها دراسة تدعى empa reg https://t.co/TC5nV80Hx2

Apr 4, 2023 · 1 like · 88,804 followers View post →
Nico Gagelmann
@NicoGagelmann · X

RT @Eddie_Cliff: @NicoGagelmann @nihardesai7 @RahulBanerjeeMD @HadidiSamer @tomam04 @Dr_AmerZeidan @gulderenesra I can’t go past EMPA REG -…

Mar 5, 2023 · 2 shares · 49,318 followers View post →
David Russler-Germain, MD/PhD
@dgermain21 · X

RT @Eddie_Cliff: @NicoGagelmann @nihardesai7 @RahulBanerjeeMD @HadidiSamer @tomam04 @Dr_AmerZeidan @gulderenesra I can’t go past EMPA REG -…

Mar 5, 2023 · 2 shares · 3,691 followers View post →
Eddie Cliff
@Eddie_Cliff · X

@NicoGagelmann @nihardesai7 @RahulBanerjeeMD @HadidiSamer @tomam04 @Dr_AmerZeidan @gulderenesra I can’t go past EMPA REG - paradigm shifting not only in demonstrating the utility of SGLT2is but also in setting the bar for new diabetes & metabolism drugs as mortality / MACE not just HbA1c (and yes, I used to want to do endo!) https://t.co/cgBsUfoLxw https://t.co/KUA5p9ym20

Mar 5, 2023 · 12 likes · 2 shares · 4,674 followers View post →
Elyar Zeynalov
@elyar_zeynalov · X

EMPA-REG OUTCOME Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes | NEJM https://t.co/5bO5alnX8O

Feb 4, 2023 · 256 followers View post →
Matthew Herper
@matthewherper · X

@Pharmaheretic @geochurch 15% reduction in all-cause mortality, driven by CV. https://t.co/ieTBb0LmcQ 32% reduction in death from any cause: https://t.co/uj8Khq6dNw

Feb 1, 2023 · 109,997 followers View post →
Dr Agibus
@Dr_Agibus · X

@tolquen @DocTotoscope c'est sur le total set, parce que c'était ce qui était écrit dans le protocole comme analyse principale et ça, ça n'a pas été modifié. Ca aurait posé plus problème l'analyse ppale était sur chaque sous groupe et que l'total set ait été un critère 2ndr . https://t.co/kcAukiBHUd

Jan 27, 2023 · 8,957 followers View post →
Ahmed Mohsen
@drahmedmohsen85 · X

RT @cardiomet_CE: 8) The first suggestions that #SGLT2i could substantially slow progression of #CKD in people with #T2D appeared in 2015 f…

Jan 1, 2023 · 2 shares · 23,373 followers View post →
Prof Kausik Ray FMedSci
@ProfKausikRay · X

RT @cardiomet_CE: 8) The first suggestions that #SGLT2i could substantially slow progression of #CKD in people with #T2D appeared in 2015 f…

Dec 28, 2022 · 2 shares · 6,013 followers View post →
cardio-met
@cardiomet_CE · X

8) The first suggestions that #SGLT2i could substantially slow progression of #CKD in people with #T2D appeared in 2015 from the seminal EMPA-REG OUTCOME trial of #empagliflozin. See

Dec 28, 2022 · 5 likes · 2 shares · 4,204 followers View post →
DidemTurgut
@didemturgut_ · X

RT @ckd_ce: 8) The first suggestions that #SGLT2i could substantially slow progression of #CKD in people with #T2D appeared in 2015 from th…

Dec 4, 2022 · 1 share · 918 followers View post →
@CKD_ce
@ckd_ce · X

8) The first suggestions that #SGLT2i could substantially slow progression of #CKD in people with #T2D appeared in 2015 from the seminal EMPA-REG OUTCOME trial of #empagliflozin. See

Dec 1, 2022 · 5 likes · 1 share · 2,640 followers View post →
Muhammad Tahir
@tauhair · X

RT @mendesthiagob: 2015: EMPA-REG surprise! The trial was designed to test empagliflozin non-inferiority for CV outcomes in pts with T2DM…

Oct 30, 2022 · 1 share · 239 followers View post →
Endocrine dialogues
@EndoDialogues · X

2015: EMPA-REG surprise! The trial was designed to test empagliflozin non-inferiority for CV outcomes in pts with T2DM and high CV risk. Result: empagliflozin was superior to placebo and reduced several MACE, including death from any cause. https://t.co/6VIrn3NksE 9/20

Oct 29, 2022 · 41 likes · 1 share · 6,465 followers View post →
Dr Perry V Mayer
@drpvmayer · X

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes — NEJM https://t.co/C5Onu04RNZ

Oct 7, 2022 · 406 followers View post →
SciSpace
@scispace · X

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes. Read more here: https://t.co/ecTXb4nCb1 @ChristophWanne4 @woerle_hans @durocherlab @Boehringer @Yale @NEJM #science #medicine #health #research https://t.co/wLT9RhdeGl

Sep 29, 2022 · 84,944 followers View post →
جوزاء
@9Sunset914 · X

RT @drjoharji1: مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في من…

Aug 27, 2022 · 21 shares · 177 followers View post →
SA
@SafyahL · X

RT @drjoharji1: مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في من…

Aug 26, 2022 · 21 shares · 11 followers View post →
سعود الظاهر
@s_fkhry · X

RT @drjoharji1: مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في من…

Aug 25, 2022 · 21 shares · 40 followers View post →
Mr Al
@MrAl70197009 · X

RT @drjoharji1: مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في من…

Aug 25, 2022 · 21 shares · 4 followers View post →
بدر العنزي
@lo9vt6C5OhVAwQB · X

RT @drjoharji1: مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في من…

Aug 25, 2022 · 21 shares · 1,235 followers View post →
Fatimah Alasiri
@alasmyah · X

RT @drjoharji1: مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في من…

Aug 25, 2022 · 21 shares · 353 followers View post →
Jamal Althagafi
@JSCJ2016 · X

RT @drjoharji1: مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في من…

Aug 25, 2022 · 21 shares · 225 followers View post →
khadeeja Al qattan
@byway77 · X

RT @drjoharji1: مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في من…

Aug 25, 2022 · 21 shares · 105 followers View post →
Dr.hassan
@hs8013 · X

RT @drjoharji1: مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في من…

Aug 25, 2022 · 21 shares · 76 followers View post →
ŦA
@talshakh · X

RT @drjoharji1: مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في من…

Aug 25, 2022 · 21 shares · 100 followers View post →
Sultan Aleesi
@sultanaleesi · X

RT @drjoharji1: مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في من…

Aug 25, 2022 · 21 shares · 1,216 followers View post →
Hayoona Humood
@HayoonaHumood · X

RT @drjoharji1: مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في من…

Aug 25, 2022 · 21 shares · 281 followers View post →
N0_0F
@berschuss1 · X

RT @drjoharji1: مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في من…

Aug 25, 2022 · 21 shares · 6,629 followers View post →
د.عبدالرحمن جوهرجي
@drjoharji1 · X

مريض سكري + جلطات قلبية او دماغية او نقص تروية في الاطراف PAD مهم خطته العلاجية تكون محتوية على دواء له ميزة اضافية في منع الجلطات توجد عدة ادوية منها جارديانس متوفر في #وصفتي وجدت دراسة empa reg انه يقلل وفيات القلب بنسبة ٣٨٪وجلطات القلب١٣٪ https://t.co/TC5nV7J68s https://t.co/AjBinTTySF

Aug 25, 2022 · 100 likes · 21 shares · 88,804 followers View post →
Raj Mehta
@raj_mehta · X

@djc795 @DavidLBrownMD @kaulcsmc @VictorDayan1 @gbiondizoccai @MDPIOpenAccess I think SGLT2 should also be included. EMPA-REG RCT https://t.co/b3O7sFVmFi

Aug 2, 2022 · 2 likes · 2,137 followers View post →
Dr. Om Lakhani, MD, DNB (ENDO)
@omlakhani · X

@usambcuba @TheEatRightMonk @aga_pallavi @doc_hormone @parthaskar @NEJM This is some obscure journal . Not @NEJM

Jun 22, 2022 · 13,157 followers View post →
cardio-met
@cardiomet_CE · X

24b) Other #DPP4i, #basal #insulin, and α-GI are neutral but and @GLP1 RAs have modest benefit from meta-analysis. #SGLT2i show consistent and robust benefits. Consider

May 11, 2022 · 3 likes · 4,204 followers View post →
Dr Perry V Mayer
@drpvmayer · X

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes — NEJM https://t.co/C5Onu04RNZ

Mar 14, 2022 · 406 followers View post →
SABOURETCardiologist
@SABOURETCardio · X

#SGLT2i #Empagliflozin The sage started more than 6 years ago. #DT2 #CKD #HF https://t.co/ewCFhmhJFi

Jan 22, 2022 · 6 likes · 1 share · 31,318 followers View post →
DFH
@5salhamid · X

RT @mendesthiagob: The year is 2015 Empagliflozin, a SGLT2i, is the first of the class to show important benefits beyond glucose control:…

Jan 16, 2022 · 2 shares · 127 followers View post →
hanif_gienoy
@hanif_gienoy · X

RT @mendesthiagob: The year is 2015 Empagliflozin, a SGLT2i, is the first of the class to show important benefits beyond glucose control:…

Jan 15, 2022 · 2 shares · 285 followers View post →
Endocrine dialogues
@EndoDialogues · X

The year is 2015 Empagliflozin, a SGLT2i, is the first of the class to show important benefits beyond glucose control: ⬇️ HF admission, ⬇️ death from cardiovascular cause and ⬇️ death from any cause in pts with T2D and ⬆️ CV risk EMPA-REG https://t.co/iQKjxE69UN (6/13)

Jan 15, 2022 · 25 likes · 2 shares · 6,465 followers View post →
MacroFour
@MacroFour · X

@FrogHarmless @Tom_Babington1 @Nickle1011 @OlivePufa EMPAREG-OUTCOME https://t.co/emu8124Ki5

Nov 8, 2021 · 6,056 followers View post →
Aakash Shingada, DNB, MRCP(UK), FASN
@aakashshingada · X

RT @Nephro_Sparks: Dr. Braunwald points out the the EMPA-REG trial was one of the most impactful clinical trials performed. Was a safety t…

Oct 16, 2021 · 18 shares · 3,050 followers View post →
Augusto Cesar S Santos Jr
@acssjr · X

RT @Nephro_Sparks: Dr. Braunwald points out the the EMPA-REG trial was one of the most impactful clinical trials performed. Was a safety t…

Oct 15, 2021 · 18 shares · 879 followers View post →
Sophia Ambruso
@sophia_kidney · X

RT @Nephro_Sparks: Dr. Braunwald points out the the EMPA-REG trial was one of the most impactful clinical trials performed. Was a safety t…

Oct 15, 2021 · 18 shares · 1,986 followers View post →
Lucky Cuenza MD FACC
@luckscuenzamd · X

RT @Nephro_Sparks: Dr. Braunwald points out the the EMPA-REG trial was one of the most impactful clinical trials performed. Was a safety t…

Oct 15, 2021 · 18 shares · 546 followers View post →
Pablo Angeles Tacchino
@pabloange · X

RT @Nephro_Sparks: Dr. Braunwald points out the the EMPA-REG trial was one of the most impactful clinical trials performed. Was a safety t…

Oct 14, 2021 · 18 shares · 758 followers View post →
Bruce Horowitz
@blhorowitz · X

RT @Nephro_Sparks: Dr. Braunwald points out the the EMPA-REG trial was one of the most impactful clinical trials performed. Was a safety t…

Oct 14, 2021 · 18 shares · 80 followers View post →
Mike Martínez Rojas
@MRMike_MD · X

RT @Nephro_Sparks: Dr. Braunwald points out the the EMPA-REG trial was one of the most impactful clinical trials performed. Was a safety t…

Oct 14, 2021 · 18 shares · 361 followers View post →
Ehsan Nobakht
@Ehsan_Nob · X

RT @Nephro_Sparks: Dr. Braunwald points out the the EMPA-REG trial was one of the most impactful clinical trials performed. Was a safety t…

Oct 14, 2021 · 18 shares · 260 followers View post →
juan ramon
@RamonTasmania · X

RT @Nephro_Sparks: Dr. Braunwald points out the the EMPA-REG trial was one of the most impactful clinical trials performed. Was a safety t…

Oct 14, 2021 · 18 shares · 95 followers View post →
Janani Rangaswami
@RangaswJ · X

RT @Nephro_Sparks: Dr. Braunwald points out the the EMPA-REG trial was one of the most impactful clinical trials performed. Was a safety t…

Oct 14, 2021 · 18 shares · 1,293 followers View post →
Carmen Cajina
@CajinaCarmen · X

RT @Nephro_Sparks: Dr. Braunwald points out the the EMPA-REG trial was one of the most impactful clinical trials performed. Was a safety t…

Oct 14, 2021 · 18 shares · 1,177 followers View post →
Dr.Roberto Collazo-Maldonado
@collazor1 · X

RT @Nephro_Sparks: Dr. Braunwald points out the the EMPA-REG trial was one of the most impactful clinical trials performed. Was a safety t…

Oct 14, 2021 · 18 shares · 1,899 followers View post →
natural killer
@manojsomagutta · X

RT @Nephro_Sparks: Dr. Braunwald points out the the EMPA-REG trial was one of the most impactful clinical trials performed. Was a safety t…

Oct 14, 2021 · 18 shares · 71 followers View post →
Wisit Cheungpasitporn MD FACP | FASN | FAST
@wisit661 · X

RT @Nephro_Sparks: Dr. Braunwald points out the the EMPA-REG trial was one of the most impactful clinical trials performed. Was a safety t…

Oct 14, 2021 · 18 shares · 2,746 followers View post →
Henry Han
@HanCardiomd · X

RT @Nephro_Sparks: Dr. Braunwald points out the the EMPA-REG trial was one of the most impactful clinical trials performed. Was a safety t…

Oct 14, 2021 · 18 shares · 16,190 followers View post →
Abraham E. Gracia R.
@Abraham_RMI · X

RT @Nephro_Sparks: Dr. Braunwald points out the the EMPA-REG trial was one of the most impactful clinical trials performed. Was a safety t…

Oct 14, 2021 · 18 shares · 4,680 followers View post →
Matthew Sparks, MD
@Nephro_Sparks · X

Dr. Braunwald points out the the EMPA-REG trial was one of the most impactful clinical trials performed. Was a safety trial and actually showed benefit SGLT2i now considered the statins of the 21st century Remarkable Braunwald is a #flozinator https://t.co/E3lGFseGHc https://t.co/6xTbRHiMfD

Oct 14, 2021 · 66 likes · 18 shares · 21,182 followers View post →
cardio-met
@cardiomet_CE · X

32) Want a

Sep 1, 2021 · 3 likes · 4,204 followers View post →
Dr Perry V Mayer
@drpvmayer · X

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes — NEJM https://t.co/C5Onu04RNZ

Jul 24, 2021 · 406 followers View post →
Endocrine dialogues
@EndoDialogues · X

EMPA-REG was the first trial after 2008 FDA guidance to be converted from noninferiority to superiority as it showed more than safety, it showed benefits! What a landmark! -->35% reduction in HF hospital admissions. https://t.co/iQKjxE69UN

Jul 16, 2021 · 2 likes · 6,465 followers View post →
Linda
@wordfinga · X

RT @cardiomet_CE: 11) In the 4 initial CV outcomes trials, #CV death was subject to the most heterogeneity, and was most evident in EMPA-RE…

May 26, 2021 · 1 share · 4,581 followers View post →
cardio-met
@cardiomet_CE · X

11) In the 4 initial CV outcomes trials, #CV death was subject to the most heterogeneity, and was most evident in EMPA-REG OUTCOME (10.1056/NEJMoa1504720). Less is known about the exact modes of death that #SGLT2i protect against.

May 26, 2021 · 8 likes · 1 share · 4,204 followers View post →
Yasser UMKCRCT
@ymhs92 · X

EMPA-REG: Empagliflozin (SGLT-2I) was associated with lower all-cause and CV death and hospitalizations for HF among patients with type 2 diabetes. Genital infections were higher with Empagliflozin. #UMKCRCT https://t.co/6wUCEQZG9T

Mar 20, 2021 · 10 followers View post →
Endocrine dialogues
@EndoDialogues · X

Since then, RCTs dedicated to assessing CVD outcomes in type 2 diabetes treatment were designed for each new drug. Empagliflozin was the first drug to show not only it was safe for CVD outcomes but protective. https://t.co/iQKjxE69UN

Mar 20, 2021 · 4 likes · 6,465 followers View post →
Juan Senior
@jsenior64 · X

RT @jsenior64: ISGLT-2 y desenlaces cardiovasculares. El que empezó todo. https://t.co/JMVQIySdqK

Mar 1, 2021 · 3 shares · 11,079 followers View post →
Sorpresivo
@hectorgomezdoct · X

RT @jsenior64: ISGLT-2 y desenlaces cardiovasculares. El que empezó todo. https://t.co/JMVQIySdqK

Jan 12, 2021 · 3 shares · 2,896 followers View post →
Dr Carlos Palacio - Diabetes
@PalacioDr · X

RT @jsenior64: ISGLT-2 y desenlaces cardiovasculares. El que empezó todo. https://t.co/JMVQIySdqK

Jan 11, 2021 · 3 shares · 92 followers View post →
Juan Senior
@jsenior64 · X

ISGLT-2 y desenlaces cardiovasculares. El que empezó todo. https://t.co/JMVQIySdqK

Jan 11, 2021 · 7 likes · 3 shares · 11,079 followers View post →
Gustavo Lenci Marques MD, PhD
@LenciMarques · X

2015: Esse ano teve muitos trabalhos relevantes, mas optei por escolher o EMPAREG. Ele trouxe o primeiro antidiabético oral reduzindo mortalidade CV de modo significativo e abriu portas para todos os usos que temos hoje dos iSGLT-2. Ref: https://t.co/cuoO0pJ09A

Dec 26, 2020 · 1 like · 415 followers View post →
Jefferson Internal Medicine Residency Program
@JeffMedChiefs · X

The correct answer is D. Empagliflozin slows progression of CKD (Creedence Trial) and decreases HF Mort. (Empa-Reg). Weirdly enough Dapagliflozin even decreases HF mortality in those without DM (Dapa-HF)! https://t.co/uQgWHBCtOK https://t.co/OXfmH0xdNX https://t.co/ejiDl9xakh https://t.co/kOM3bZIjde

Sep 28, 2020 · 2,111 followers View post →
Prof Derek Connolly
@DrDerekConnolly · X

@drshafikuchay @AmarPut @kamleshkhunti @AbdTahrani @SABOURETCardio @DrMarthaGulati @GiuseppeGalati_ I very much use them [appropriately] on a daily basis and will use them more as the SmPC indications, @NICEComms and @escardio guidance changes so far [since EMPA-REG] I have had no issues https://t.co/ulqAzvBv49 https://t.co/4QQ5GVcCmC

Sep 19, 2020 · 3 likes · 3,937 followers View post →
TheAntiCommuniss
@AntiCommuniss · X

RT @DiscoStew66: If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.c…

Aug 30, 2020 · 20 shares · 45 followers View post →
Leland Sandfort
@leland_sandfort · X

RT @DiscoStew66: If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.c…

Aug 29, 2020 · 20 shares · 1,056 followers View post →
pōhutukawa
@pohutukawa · X

RT @DiscoStew66: If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.c…

Aug 29, 2020 · 20 shares · 576 followers View post →
The Secular Conservative
@RoguePhilosoph · X

RT @DiscoStew66: If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.c…

Aug 29, 2020 · 20 shares · 581 followers View post →
ASCORBIC_CARNIVORE
@cryptowavesurfr · X

RT @DiscoStew66: If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.c…

Aug 29, 2020 · 20 shares · 295 followers View post →
Bahmann
@sanzo0260 · X

RT @DiscoStew66: If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.c…

Aug 29, 2020 · 20 shares · 255 followers View post →
colin sullivan
@colinsatwit · X

RT @DiscoStew66: If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.c…

Aug 29, 2020 · 20 shares · 188 followers View post →
P.D. Mangan Health & Freedom Maximalist
@Mangan150 · X

RT @DiscoStew66: If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.c…

Aug 29, 2020 · 20 shares · 294,050 followers View post →
Eduardo Rico
@EduardoRicoER · X

RT @DiscoStew66: If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.c…

Aug 29, 2020 · 20 shares · 103 followers View post →
Peter Österberg, Ph.D.
@Genlearnman · X

RT @DiscoStew66: If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.c…

Aug 29, 2020 · 20 shares · 1,427 followers View post →
Hold Me Accountable
@KetoAccountabi1 · X

RT @DiscoStew66: If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.c…

Aug 29, 2020 · 20 shares · 1,277 followers View post →
د.دلال أسامة الكاظمي
@Dalal_Alkazemi · X

RT @DiscoStew66: If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.c…

Aug 29, 2020 · 20 shares · 4,566 followers View post →
Keto4Life
@keto4_life · X

RT @DiscoStew66: If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.c…

Aug 29, 2020 · 20 shares · 844 followers View post →
David Wyant
@wyadvd · X

RT @DiscoStew66: If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.c…

Aug 29, 2020 · 20 shares · 2,691 followers View post →
H at large
@gaiashining · X

RT @DiscoStew66: If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.c…

Aug 29, 2020 · 20 shares · 655 followers View post →
ActivatedNutJob
@ActivatedNutJob · X

RT @DiscoStew66: If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.c…

Aug 29, 2020 · 20 shares · 404 followers View post →
Joseph Emmanuel
@CancerRideOct · X

RT @DiscoStew66: If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.c…

Aug 29, 2020 · 20 shares · 919 followers View post →
LowCarbCarla
@LowCarbCarla · X

RT @DiscoStew66: If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.c…

Aug 29, 2020 · 20 shares · 844 followers View post →
DiscoStew
@DiscoStew66 · X

If cardiovascular disease can be REDUCED whilst INCREASING LDL, the Diet-Heart Hypothesis has been falsified. https://t.co/CpJfIdLO9c

Aug 29, 2020 · 68 likes · 20 shares · 10,795 followers View post →
DiscoStew
@DiscoStew66 · X

“Empagliflozin has been associated with an increase in levels of both low-density lipoprotein (LDL)and high-density lipoprotein (HDL) cholesterol. The most common side effects of empagliflozin are urinary tract infection and genital infection”

Aug 27, 2020 · 1 like · 10,795 followers View post →
movedoc
@movedoc · X

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes | NEJM https://t.co/lhAj4kBfXL

Feb 13, 2020 · 487 followers View post →
liyu
@Liyu1036201493 · X

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes | NEJM https://t.co/or2Y2D15xu

Aug 5, 2019 · 71 followers View post →
Vanessa-essa
@VYanza99 · X

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes https://t.co/l58AvoFo3b via @YouTube @mjack2050

Jun 19, 2019 · 241 followers View post →
B. Wagner, M.D.
@Wagner_Nephro · X

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes—cited by Dr. Joel Topf, MD, FACP, St. Clair University @kidney_boy #KidneyCon “It actually saved lives.” https://t.co/Hw6gIuLBqq

Apr 13, 2019 · 3 likes · 3,325 followers View post →
Yolanda Morcillo Muñoz
@yolandamorcill1 · X

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes | NEJM https://t.co/1u4QzHVEQQ

Mar 26, 2019 · 724 followers View post →
Joel Topf
@kidneyboy.bsky.social · Bluesky

#VisualAbstract for EMPA-REG. First take, happy to hear feedback and make changes. http://www.nejm.org/doi/full/10.1056/NEJMoa1504720#t=article

Oct 15, 2017 View post →
Joel Topf
@kidneyboy.bsky.social · Bluesky

First time we have seen a reduction in mortality with oral hypoglycemic? http://www.nejm.org/doi/full/10.1056/NEJMoa1504720?query=featured_home#abstract

Sep 18, 2015 View post →