Nat Neurosci October 2015 PMID 26404710

Mechanisms of stress in the brain.

Bruce S McEwen, Nicole P Bowles, Jason D Gray, Matthew N Hill, Richard G Hunter, Ilia N Karatsoreos, Carla Nasca

Mentions

65
Peak: 9 in Nov 2021
across 6 sources since Sep 2015

Extended reach

210,418
potential audience

Total likes

9,837

Video views

108,245

Mentions per month

Sep 2015 – Feb 2025

Where it's discussed

  • News23 articles
  • X / Twitter21 posts
  • Facebook14 posts
  • Blogs4 articles
  • YouTube2 videos
  • Bluesky1 posts

AI synopsis

What people are saying

Overall, the discussions show a strong consensus on the significance of understanding stress mechanisms, exemplified by phrases like 'very honored to speak' and references to influential scientists such as Bruce McEwen, which demonstrate both respect and interest. The tone varies from admiration to scholarly links, indicating that the publication resonates within the neuroscience community without overwhelming discourse.

AgreementModerate agreement

Most comments express respect, recognition, or general acceptance of the importance of the article, with some explicitly praising the contribution of researchers like Bruce McEwen.

InterestHigh interest

Numerous discussions highlight excitement about the topic, referencing presentations, collaborations, and scientific communities interested in stress mechanisms.

EngagementModerate engagement

Comments range from brief acknowledgments of the research to mentions of personal or academic involvement, indicating moderate depth of engagement.

ImpactModerate impact

The discussions reflect that the article and related research have meaningful influence in neuroscience, especially regarding stress and brain mechanisms, though not universally transformative.

Abstract in brief

  • The brain perceives and adapts to social and physical stressors through complex mechanisms involving changes from cell surface interactions to epigenetic regulation, leading to structural remodeling of neural architecture.
  • Key mediators in these processes include excitatory amino acids, glucocorticoids, endocannabinoids, and BDNF, which influence gene expression via epigenetic modifications like histone changes and DNA methylation.
  • Understanding these mechanisms helps explain brain plasticity and vulnerability, which is crucial for developing treatments for anxiety, depression, and age-related cognitive decline.]

Top posts

Most liked on X and Bluesky
Patricia P. Silveira
@SilveiraPP · X

Very honoured to be speaking at #SfN21 in a session that was put together as a tribute to the giant Bruce McEwen: “Mechanisms of Stress in the Brain and Beyond” minisymposium, on Thursday at 3:30 EST. Check it out! @LudmerCentre @McGillMed @DouglasResearch @IPNMcGill https://t.co/p6yC3hGx3a

Nov 8, 2021 · 31 likes · 8 shares · 395 followers View post →
Raghu Padinjat പടിഞാററ് രഘൂ
@RPadinjat · X

New work by Shona Chattarji and colleagues. Mechanisms of stress in the brain. @NCBS_Bangalore https://t.co/jhFXtb15IC

Dec 18, 2019 · 14 likes · 1,265 followers View post →
CLaE
@leafs_s · X

Nature Neuroscience 25 September 2015 Bruce McEwen Mechanisms of stress in the brain https://t.co/WAbbrRISS4 https://t.co/UE0qnLAOVg

Jan 18, 2020 · 12 likes · 2 shares · 28,486 followers View post →
Curious Lady
@curious_ladyyy · X

• كيف تؤثر الصدمات على وظائف الجسم؟ - اختلال في محور التوتر: يتحكم هذا المحور في إفراز هرمون الكورتيزول المسؤول عن الاستجابة للتوتر. عندما يتعرض الطفل لصدمات، يصبح هذا النظام في حالة اضطراب مستمر، مما يؤدي إلى زيادة مستويات التوتر المزمنة. - المصدر: https://t.co/UtypzmMrfe

Feb 7, 2025 · 7 likes · 20,937 followers View post →
Neuroscience for All
@NeurosciforAll · X

Nov 18, 2024 · 3 likes · 12 followers View post →
cass/della
@cassvivv · X

I have to read and do a 15 minute presentation on a paper and I am terrified why can’t I have something simple and not THE MECHANISMS OF STRESS IN THE BRAIN

Oct 23, 2020 · 1 like · 840 followers View post →

All mentions

Curious Lady
@curious_ladyyy · X

• كيف تؤثر الصدمات على وظائف الجسم؟ - اختلال في محور التوتر: يتحكم هذا المحور في إفراز هرمون الكورتيزول المسؤول عن الاستجابة للتوتر. عندما يتعرض الطفل لصدمات، يصبح هذا النظام في حالة اضطراب مستمر، مما يؤدي إلى زيادة مستويات التوتر المزمنة. - المصدر: https://t.co/UtypzmMrfe

Feb 7, 2025 · 7 likes · 20,937 followers View post →
Neuroscience for All
@NeurosciforAll · X

Nov 18, 2024 · 3 likes · 12 followers View post →
Alice Morgunova
@alice_morgunova · X

RT @SilveiraPP: Very honoured to be speaking at #SfN21 in a session that was put together as a tribute to the giant Bruce McEwen: “Mechanis…

Nov 9, 2021 · 8 shares · 133 followers View post →
Ed the axon whisperer
@ed_ruthazer · X

RT @SilveiraPP: Very honoured to be speaking at #SfN21 in a session that was put together as a tribute to the giant Bruce McEwen: “Mechanis…

Nov 8, 2021 · 8 shares · 1,127 followers View post →
Luciano S. de Fraga
@lsdefraga · X

RT @SilveiraPP: Very honoured to be speaking at #SfN21 in a session that was put together as a tribute to the giant Bruce McEwen: “Mechanis…

Nov 8, 2021 · 8 shares · 260 followers View post →
Dr. M. Natasha Rajah, PhD
@mnrajah · X

RT @SilveiraPP: Very honoured to be speaking at #SfN21 in a session that was put together as a tribute to the giant Bruce McEwen: “Mechanis…

Nov 8, 2021 · 8 shares · 3,004 followers View post →
Eduardo Zimmer
@erzimmer · X

RT @SilveiraPP: Very honoured to be speaking at #SfN21 in a session that was put together as a tribute to the giant Bruce McEwen: “Mechanis…

Nov 8, 2021 · 8 shares · 3,938 followers View post →
CAN ACN
@CAN_ACN · X

RT @SilveiraPP: Very honoured to be speaking at #SfN21 in a session that was put together as a tribute to the giant Bruce McEwen: “Mechanis…

Nov 8, 2021 · 8 shares · 6,820 followers View post →
Douglas Research Centre
@DouglasResearch · X

RT @SilveiraPP: Very honoured to be speaking at #SfN21 in a session that was put together as a tribute to the giant Bruce McEwen: “Mechanis…

Nov 8, 2021 · 8 shares · 1,884 followers View post →
Dr. Angélica Torres-Berrío
@angelica_atb · X

RT @SilveiraPP: Very honoured to be speaking at #SfN21 in a session that was put together as a tribute to the giant Bruce McEwen: “Mechanis…

Nov 8, 2021 · 8 shares · 2,113 followers View post →
Patricia P. Silveira
@SilveiraPP · X

Very honoured to be speaking at #SfN21 in a session that was put together as a tribute to the giant Bruce McEwen: “Mechanisms of Stress in the Brain and Beyond” minisymposium, on Thursday at 3:30 EST. Check it out! @LudmerCentre @McGillMed @DouglasResearch @IPNMcGill https://t.co/p6yC3hGx3a

Nov 8, 2021 · 31 likes · 8 shares · 395 followers View post →
Nattha Saravutanukul
@n3nnnnn · X

RT @n3nnnnn: Mechanisms of #stress in the brain | Nature Neuroscience https://t.co/uPUgjYz8P7

Oct 28, 2020 · 1 share · 366 followers View post →
cass/della
@cassvivv · X

I have to read and do a 15 minute presentation on a paper and I am terrified why can’t I have something simple and not THE MECHANISMS OF STRESS IN THE BRAIN

Oct 23, 2020 · 1 like · 840 followers View post →
Nattha Saravutanukul
@n3nnnnn · X

Mechanisms of #stress in the brain | Nature Neuroscience https://t.co/uPUgjYz8P7

Jan 26, 2020 · 1 like · 1 share · 366 followers View post →
CLaE
@leafs_s · X

RT @leafs_s: Nature Neuroscience 25 September 2015 Bruce McEwen Mechanisms of stress in the brain https://t.co/WAbbrRISS4 https://t.co/…

Jan 20, 2020 · 2 shares · 28,486 followers View post →
wolodya
@wolodya · X

RT @leafs_s: Nature Neuroscience 25 September 2015 Bruce McEwen Mechanisms of stress in the brain https://t.co/WAbbrRISS4 https://t.co/…

Jan 19, 2020 · 2 shares · 1,071 followers View post →
CLaE
@leafs_s · X

Nature Neuroscience 25 September 2015 Bruce McEwen Mechanisms of stress in the brain https://t.co/WAbbrRISS4 https://t.co/UE0qnLAOVg

Jan 18, 2020 · 12 likes · 2 shares · 28,486 followers View post →
Cat Lau
@scicommcat · X

Sad to hear about the passing of #BruceMcEwen - I read so many of his publications during graduate school when I was conducting research on effects of stress in the #hippocampus. Such an influential scientist who helped us better understand mechanisms of #stress in the #brain. https://t.co/xRsCbEmZTS

Jan 16, 2020 · 1 like · 301 followers View post →
Valeri Vasilev
@DiogenesOfSofia · X

"Mechanisms of stress in the brain". https://t.co/UNgyCUVHvr

Jan 5, 2020 · 105 followers View post →
Valeri Vasilev
@DiogenesOfSofia · X

"Mechanisms of stress in the brain" https://t.co/UNgyCUVHvr

Jan 4, 2020 · 105 followers View post →
Raghu Padinjat പടിഞാററ് രഘൂ
@RPadinjat · X

New work by Shona Chattarji and colleagues. Mechanisms of stress in the brain. @NCBS_Bangalore https://t.co/jhFXtb15IC

Dec 18, 2019 · 14 likes · 1,265 followers View post →
Caitlin Vander Weele, PhD
@caitvw.bsky.social · Bluesky

"Mechanisms of stress" in the brain http://go.nature.com/zVMzGE I see you in there @canna_brain

Sep 25, 2015 View post →