The collective discussions reflect a predominantly positive view of the article, with comments emphasizing its safety and efficacy, such as noting that nicotinamide reduces skin cancers by up to 30%, and references to longstanding use and studies, which reveal a tone of cautious optimism centered on health benefits and clinical relevance.
AgreementModerate agreement
Most discussions acknowledge the positive findings and safety of nicotinamide, showing general agreement with the study's conclusions.
InterestHigh interest
Social discussions demonstrate high interest, with mentions of the potential for skin cancer prevention and references to reputable studies.
EngagementModerate engagement
Posts show some depth by referencing specific studies, background information, and health implications, though most are brief responses.
ImpactModerate impact
The discussions suggest some awareness of the potential clinical significance of niacinamide for skin cancer prevention, but widespread adoption or policy impact remains uncertain.
Abstract in brief
This study tested whether nicotinamide (vitamin B3) can help prevent skin cancers caused mainly by UV exposure.
It found that taking nicotinamide twice daily for a year significantly reduced the number of new nonmelanoma skin cancers and actinic keratoses compared to a placebo.
The treatment was also safe, with no major differences in side effects between the nicotinamide and placebo groups.]
@kelseykenney144 @iamjustapeater @MineralChief https://t.co/HvyHpFANZt
https://t.co/R4DZc3NTV7
"..Nicotinamide has been used at pharmacologic doses (up to 3g daily) over MANY YEARS with minimal side effects".
https://t.co/Mcy8MdOMEd
https://t.co/kCI8rLYsfx
"..aspirin..1,300 mg/day...There were no significant adverse effects."
Feb 19, 2025 · 42 likes · 31,866 followersView post →
Feb 10, 2020 · 8 likes · 1 share · 4,606 followersView post →
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Christina Ha MD
@tinahamd · X
George Martin - vitamin B3 500mg twice daily May decrease risk of non-melanoma skin cancer @MauiDerm https://t.co/9iIxYlwxyA learn something new all the time! Should we be recommending to our IBD pts? @GuildConference @MLongMD
Feb 18, 2020 · 8 likes · 3 shares · 2,961 followersView post →
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Will Brink
@WillBrink · X
Easy to find inexpensive supplement may reduce your risk of the most common skin cancers:
"Oral nicotinamide was safe and effective in reducing the rates of new nonmelanoma skin cancers and actinic keratoses in high-risk patients."
https://t.co/HjjTxAtDdw
@NoleMami @DCGreenZone1 @pmcdunnough @BorosBruce @dwmoskowitz You may not need more than adequate doses of #QuercetinZinc for #C19 IF Treated @ Symptom Onset (or prophylaxis). I take most of those for general health, except I've only used Niacinamide (haven't used Flush Niacin yet): https://t.co/jO3EE9kIUT for skin:
https://t.co/xE7wdA1MH1
Aug 30, 2021 · 5 likes · 1 share · 3,493 followersView post →
This video explores whether NAD supplements can increase cancer risk, analyzing recent studies and addressing common misconceptions. Scientific evidence suggests that NAD's role in DNA repair and cellular energy may not…
Discover the benefits of hyaluronic acid and nicotinamide for skin health. This video covers recent studies showing how these compounds can improve skin hydration and prevent skin cancers caused by UV exposure.
With the popularity of NAD in health please include niacinamide / nicotinamide (Vitamin B3) https://t.co/gHRNXvXdnv
https://t.co/hLDZL3DlLR
#x #doctor #health #cancer #oncology #cancertreatment #oncologynews #skin #skincancer #vitamin #vitaminB #vitaminb3 #b3 #nad #nmn #nr https://t.co/OS0CFd7NbC
@kelseykenney144 @iamjustapeater @MineralChief https://t.co/HvyHpFANZt
https://t.co/R4DZc3NTV7
"..Nicotinamide has been used at pharmacologic doses (up to 3g daily) over MANY YEARS with minimal side effects".
https://t.co/Mcy8MdOMEd
https://t.co/kCI8rLYsfx
"..aspirin..1,300 mg/day...There were no significant adverse effects."
Feb 19, 2025 · 42 likes · 31,866 followersView post →
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WeitzSportsChiro
@WeitzSportChiro · X
Niacinamide taken orally (500 mg BID) reduces the risk of skin cancer. https://t.co/9qqhSsKDQd
Mar 31, 2024 · 1 like · 9,374 followersView post →
Easy to find inexpensive supplement may reduce your risk of the most common skin cancers:
"Oral nicotinamide was safe and effective in reducing the rates of new nonmelanoma skin cancers and actinic keratoses in high-risk patients."
https://t.co/HjjTxAtDdw
A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention
Conclusion: Oral nicotinamide safe+ effective in reducing non-melanoma skin cancers and actinic keratoses in high-risk patients. https://t.co/ES9MZpo0ff
Oral nicotinamide a safe and effective method of reducing the rates of new nonmelanoma skin cancers & actinic keratoses in high-risk patients - Phase 3 Randomised Trial of Nicotinamide for Skin-Cancer Chemoprevention | NEJM #skincancer #skin #nicotinamide https://t.co/wr6GcJfjsF
@davidasinclair Many supplements have been subject to clinical trial and are nonetheless still classified as supplements by the FDA. For example, nicotinamide, which was studied in a well known randomized trial: https://t.co/HwCEZOYS08
Dr. Steve Wang is discussing the use of niacinamide for chemoprevention of non-melanoma skin cancer (note that most of the study population was white). Original study in @NEJM: https://t.co/y4mhH5HjcP #IIDFall22 @MedscapeLIVE https://t.co/QhDKkGmUWs
Nov 4, 2022 · 2 likes · 22,068 followersView post →
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Linda Behan
@LindaBehan10 · X
A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention | NEJM https://t.co/kTnEo4XycJ
1. Nicotinamide (vitamin B3) - 500mg twice daily.
Best data overall. Shown in this NEJM article to reduce UV damage by likely by enhancing DNA repair: https://t.co/vXeOH7Mwec
Further reviewed here: https://t.co/VjEoUIdErL
RT @SeekingTruth4us: @NoleMami @DCGreenZone1 @pmcdunnough @BorosBruce @dwmoskowitz You may not need more than adequate doses of #QuercetinZ…
Aug 30, 2021 · 1 share · 3,493 followersView post →
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SeekingTruth4Humanity
@SeekingTruth4us · X
@NoleMami @DCGreenZone1 @pmcdunnough @BorosBruce @dwmoskowitz You may not need more than adequate doses of #QuercetinZinc for #C19 IF Treated @ Symptom Onset (or prophylaxis). I take most of those for general health, except I've only used Niacinamide (haven't used Flush Niacin yet): https://t.co/jO3EE9kIUT for skin:
https://t.co/xE7wdA1MH1
Aug 30, 2021 · 5 likes · 1 share · 3,493 followersView post →
CP
Charles Brenner, PhD
@CharlesMBrenner · X
@TLMe15 @banrecordholder ONTRAC study for example https://t.co/IeRbXic1Mi
Found out about this from my derm today. Thought we should know! Vitamin B3 (Nicotinamide) reduced the development of non melanoma skin cancers in high risk folk by 23%. A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention https://t.co/4jftYJqMkx
learned about nicotinamide (vitamin b3) for skin cancer prevention during derm bootcamp from @MGHPsychAcademy and found relevant @NEJM article https://t.co/OjqPvcECAY
Jan 15, 2021 · 3 likes · 1 share · 1,840 followersView post →
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Nuala Woulfe
@Nuala_Woulfe · X
Niacinamide is a popular skincare ingredient . It helps to heal the #skin_barrier , soothes #eczema & #Rosacea . It may even protect against skin cancer . A Phase 3 Randomised Trial of Nicotinamide (#Niacinamide )for Skin-Cancer Prevention | NEJM #skin https://t.co/csAoDF3LLe
@Simple_Trials @deadoc80 @txi_ber @CRCordeliers @WCM_MeyerCancer @ElementoLab @EngIPM Analogous trial completed here in Australia https://t.co/oxstyrBOqE. @BCTrialsANZ has a long-history of successfully delivering innovative trials to women with all subtypes of #breastcancer @SoozyJSmith #bcsm
Aug 4, 2020 · 3 likes · 1,576 followersView post →
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lemmiwinks
@lemmiwenks · X
@CharlesMBrenner @Blagosklonny @sakiwebo You could make argument that nejm nicotinamide cancer prevention trial is highest clinical level of evidence in field of aging for any drug https://t.co/avLxinCE3t
RT @tinahamd: George Martin - vitamin B3 500mg twice daily May decrease risk of non-melanoma skin cancer @MauiDerm https://t.co/9iIxYlwxyA…
Feb 18, 2020 · 3 shares · 5,256 followersView post →
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Devika Kapuria, MD
@KapuriaMD · X
RT @tinahamd: George Martin - vitamin B3 500mg twice daily May decrease risk of non-melanoma skin cancer @MauiDerm https://t.co/9iIxYlwxyA…
Feb 18, 2020 · 3 shares · 2,683 followersView post →
MD
Maui Derm
@MauiDerm · X
RT @tinahamd: George Martin - vitamin B3 500mg twice daily May decrease risk of non-melanoma skin cancer @MauiDerm https://t.co/9iIxYlwxyA…
Feb 18, 2020 · 3 shares · 1,319 followersView post →
CM
Christina Ha MD
@tinahamd · X
George Martin - vitamin B3 500mg twice daily May decrease risk of non-melanoma skin cancer @MauiDerm https://t.co/9iIxYlwxyA learn something new all the time! Should we be recommending to our IBD pts? @GuildConference @MLongMD
Feb 18, 2020 · 8 likes · 3 shares · 2,961 followersView post →
Feb 10, 2020 · 8 likes · 1 share · 4,606 followersView post →
CP
Charles Brenner, PhD
@CharlesMBrenner · X
@JeffreyMilton10 there's an 80 yr history of the health benefits of supplementing with niacin (NA) and nicotinamide (NAM), the conventional forms of vitamin B3. In an RCT, high dose NAM depressed skin cancer rates in a population at risk for developing skin cancer https://t.co/eA5s7zAuWH
Dec 26, 2019 · 1 like · 57,347 followersView post →
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John Oblong
@JohnOblong · X
RT @MASC_Trials: Dr Diona Damian gave an overview as to the benefits of oral nicotinamide in reducing the risk of developing further non me…
@kharmix NR is protective against development of hepatocellular cancer https://t.co/fRs6IT3SEQ and breast cancer metastasis https://t.co/0sfRoFb88d in both of which are driven by low NAD. NAM is protective against skin cancer in people https://t.co/WQZgf3VDIK /1
Apr 21, 2019 · 1 like · 57,347 followersView post →
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Gary Goldman, MD
@GaryGoldmanMD · X
@Cambria @brettistweeting @markbam @Kaitlin @giisellediaz @MariaRuthM @megbeaudet @JennyPWags Nicotinamide reduces basal and squamous cell skin cancers by 30% per the NEJM. Why isn’t this info routinely shared by every dermatologist? https://t.co/JVd46ax08r
XP Project | PDF | Dna Repair | Molecular Genetics
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doi:10.1056/nejmoa1506197. Choi, J.Y., Yun, H.H. and Lee, C.G. (2016) 'Xeroderma pigmentosum Group A with mutational hot spot (c.390-1G>C in XPA) in South ...
Nicotinamide's Role in Skin Cancer Prevention | PDF | Randomized ...
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doi:10.1056/NEJMoa1506197 collaboration's tool for assessing risk of bias in randomised tri- 11. Chung EYM, Palmer SC, Strippoli GFM. Interventions to als ...
... 10.1056/NEJMoa1506197#t=article has confirmed that over a 12 month period, the incidence of non-melanoma skin cancers were reduced by 23% in the group ...
Melbourne Skin Centre | Sandringham VIC - Facebook
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org/doi/full/10.1056/NEJMoa1506197#t=article has confirmed that over a 12 month period, the incidence of non-melanoma skin cancers were reduced by 23% in ...
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... 10.1056/NEJMoa1506197#t=article [Accessed on 27 November 2016] (2) Anonym. Activity Network Template. You might also like. Clinical Trial Timelines. PDF. No ...
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N Engl J Med. Dr Edward R. Scheffer Cliff: Research funding from Arnold 2015;373(17):1618-1626. doi:10.1056/NEJMoa1506197. Ventures. 14. De Quadros Camargo C ...
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... remedied by taking dairy? A cup of yogurt already has 300mg of phosphate. https://www.nejm.org/doi/full/10.1056/nejmoa1506197 · JoeSanta555. OP ...
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