N Engl J Med November 2015 PMID 26551272

A Randomized Trial of Intensive versus Standard Blood-Pressure Control.

Mentions

553
Peak: 17 in May 2025
across 6 sources since Nov 2015

Extended reach

1,942,697
potential audience

Total likes

27,952

Video views

773,303

Mentions per month

Nov 2015 – Dec 2025

Where it's discussed

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  • Facebook94 posts
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  • Reddit5 posts

AI synopsis

What people are saying

The collection exhibits a strong recognition of the study’s significance, with examples like references to the 25% reduction in cardiovascular events and mortality, and mentions of how the findings challenge prior norms. The tone ranges from supportive to skeptical, using words like 'game changer' and 'misinformation,' which reflect both high engagement and debate about the real-world impact of the research.

AgreementModerate agreement

Most discussions acknowledge the positive findings of the study, especially regarding the benefits of intensive blood pressure control, despite some skepticism or requests for nuance.

InterestHigh interest

The discussions demonstrate high interest, with many references to detailed results, trial specifics, and debate over clinical implications.

EngagementModerate engagement

Participants actively engage by citing studies, quoting specific results, and referencing guidelines, indicating a willingness to explore the topic in depth.

ImpactHigh impact

This collective conversation indicates that the study’s findings are influential, shaping opinions on blood pressure management and possibly affecting future guidelines.

Abstract in brief

  • A study examined the effects of different systolic blood pressure targets (less than 120 mm Hg vs. less than 140 mm Hg) on cardiovascular health in individuals without diabetes who had high cardiovascular risk.
  • After 3.26 years of monitoring, the group with the more intensive treatment (targeting less than 120 mm Hg) experienced significantly fewer major cardiovascular events and deaths compared to those with the standard treatment.
  • However, this intense treatment was associated with higher rates of some serious side effects, like low blood pressure and kidney issues, underscoring a trade-off between benefits and risks.

Top posts

Most liked on X and Bluesky
Riñón Acido
@AcidoRinon · X

@Dr_Reyner_Solis No pa. El estudio SPRINT demostró que, si bien hay un beneficio del control tensional estricto, también hay un aumento de eventos adversos. Por ende, la medicina es personalizada, siempre basada en el juicio clínico y en distintas poblaciones. 10.1056/NEJMoa1511939

Jun 21, 2025 · 93 likes · 1 share · 10,150 followers View post →
takua フリザード
@takua_scientist · X

「高血圧の基準は、どんどん下がっているんですよ」 これは事実 「金儲けのためだ!」 これは陰謀論… 単純すぎるのよ。ゆるゆるなのよ。 ↓↓↓実際(の一部)↓↓↓ 2015年 SPRINT試験「血圧120に厳密管理したほうが良くね?」 https://t.co/i6Qyw4zztD ↓

May 8, 2025 · 69 likes · 13 shares · 8,415 followers View post →
Marko Kovic
@marko_kovic · X

7/ Die Änderung der Bluthochdruck-Grenze basiert auf Daten einer grossen randomisierten Studie mit über 9’000 Proband:innen. Die Änderung gab es also wegen neuer, präziserer Evidenz. Es war nicht einfach eine willkürliche Entscheidung. https://t.co/KSchsk0Et2

May 5, 2024 · 56 likes · 2 shares · 18,400 followers View post →
Bert
@HenryRunamucker · X

Claims of efficacy are extremely dubious. The trial ends with only 34 participants out of more than 100. Most well-conducted modern trials to determine efficacy of medical treatments have thousands of participants. See this trial, for example: https://t.co/5DFGr2jW5V

Nov 11, 2020 · 31 likes · 1 share · 2,125 followers View post →
Tomo Takada
@toroeater · X

Dr Attiaが血圧が高すぎないことが大事だと言っていたことを先日のFOREVER23でシェアしました。 たまたま「血圧は心配しなくていい」と言うある先生のビデオを見て下のリサーチ結果をシェアするべきだと思いました。NEJMに載った物でとても信頼度が高い物です。 https://t.co/zYkQomJOpK #ライブラン https://t.co/hOPqSbLYeV

Apr 5, 2023 · 26 likes · 17,985 followers View post →
Nephrology Journal Club
@NephJC · X

T0c: In the

Jun 8, 2021 · 17 likes · 6 shares · 38,218 followers View post →

All mentions

CourageIsContagious
@SDHeartLed · X

RT @han_francis: @MidwesternDoc This is what you get when you systematically ignore the data you don't like https://t.co/yYAv73LCId

Nov 23, 2025 · 1 share · 269 followers View post →
Frank Han MD
@han_francis · X

@MidwesternDoc This is what you get when you systematically ignore the data you don't like https://t.co/yYAv73LCId

Nov 23, 2025 · 1 like · 1 share · 4,747 followers View post →
zuka
@zuka1973887 · X

@hikegami3 https://t.co/Q9jKaPsRUR

Oct 17, 2025 · 50 followers View post →
no kazumasa|pharmacist
@nokazumasa · X

RT @manabunoda: SPRINT試験って、一般的にはどっちを指すの? A Randomized Trial of Intensive versus Standard Blood-Pressure Control https://t.co/8dgvE4Y05u Fi…

Oct 11, 2025 · 1 share · 444 followers View post →
リンコ
@manabunoda · X

SPRINT試験って、一般的にはどっちを指すの? A Randomized Trial of Intensive versus Standard Blood-Pressure Control https://t.co/8dgvE4Y05u Final Report of a Trial of Intensive versus Standard Blood-Pressure Control https://t.co/ioWyDsPBUT

Oct 11, 2025 · 1 share · 2,793 followers View post →
Kramer Dugan
@krame10250 · X

@Lunatic__Fringe @JasonBardi @ValerieAnne1970 This is a dumb article that ignores any nuance we understand of cardiac pathophysilogy. There is Clear evidence that cardiac remodeling is halted and or reversed with more intensive BP control. https://t.co/UaF12uaylL https://t.co/vcNmTCD8gJ

Oct 5, 2025 · 145 followers View post →
Flávio Vasconcelos
@FlvioVasconce17 · X

SUA PRESSÃO 12x8 Não É Mais Normal? Veja as Novas Diretrizes AGORA! - YouTube https://t.co/RsVdGz5la6

Sep 25, 2025 · 160 followers View post →
Igor
@SDMourao · X

@ducavendish A resposta está nesse artigo https://t.co/EH9xjdHfS0 embora não seja o único, todos são livres para fazerem pesquisas mais amplas e mais confiáveis para mudarem as próximas diretrizes

Sep 19, 2025 · 403 followers View post →
Anna Cruz Johnson
@itsannabanana0 · X

RT @PetersenKe10295: @VigilantFox https://t.co/aAlmUaLmAY

Sep 13, 2025 · 1 share · 491 followers View post →
DocGonzo
@RaulGonzo33 · X

RT @DoctorMeeple: @LoboEstrategia Léete esto, porfa SPRINT Research Group. A Randomized Trial of Intensive versus Standard Blood-Pressure…

Sep 8, 2025 · 1 share · 337 followers View post →
DoctorMeeple
@DoctorMeeple · X

@LoboEstrategia Léete esto, porfa SPRINT Research Group. A Randomized Trial of Intensive versus Standard Blood-Pressure Control. NEJM, 2015;373:2103–16.

Sep 8, 2025 · 1 like · 1 share · 3,639 followers View post →
Tânia Rodrigues
@TniaRod82868724 · X

https://t.co/BiMuB1FYnX

Sep 7, 2025 · 46 followers View post →
OTAVIO
@OTAVIOPENHA · X

https://t.co/4QAg5BLyZr

Sep 5, 2025 · 14 followers View post →
Fourth Line
@fourthlinenhl · X

@ScienceGuy2718 @g74076 @ifixhearts @DrAseemMalhotra https://t.co/4pdWAcw9I9 with risks for cardiovascular disease, a goal of 120 is better than a goal of 140

Aug 31, 2025 · 156 followers View post →
Henrique
@Henrique70279 · X

https://t.co/RBTWFachMQ

Aug 28, 2025 · 488 followers View post →
forchesato
@forchesato · X

https://t.co/ztmeskvAs5

Aug 27, 2025 · 22 followers View post →
­▓╔════╗ MØz@®7 ╔═════╗­░
@m0z4r7 · X

Qual a MELHOR PRESSÃO ARTERIAL para SUA IDADE? https://t.co/qsRYekHRov via @YouTube

Aug 27, 2025 · 368 followers View post →
José Osmar Melo
@jmelo9679 · X

Qual a MELHOR PRESSÃO ARTERIAL para SUA IDADE? https://t.co/is01wDKtHh via @YouTube

Aug 26, 2025 · 48 followers View post →
Maria Gorete Lima Amaral
@MariaGoreteLi10 · X

https://t.co/d0hv5BYTT2

Aug 26, 2025 · 8 followers View post →
André Wambier
@AndreWambier · X

Olá! Assista a nosso vídeo novo que acabou de sair

Aug 26, 2025 · 179 followers View post →
Dr.NefroBoy
@iAlanagc · X

RT @AcidoRinon: @Dr_Reyner_Solis No pa. El estudio SPRINT demostró que, si bien hay un beneficio del control tensional estricto, también ha…

Jun 22, 2025 · 1 share · 68 followers View post →
Riñón Acido
@AcidoRinon · X

@Dr_Reyner_Solis No pa. El estudio SPRINT demostró que, si bien hay un beneficio del control tensional estricto, también hay un aumento de eventos adversos. Por ende, la medicina es personalizada, siempre basada en el juicio clínico y en distintas poblaciones. 10.1056/NEJMoa1511939

Jun 21, 2025 · 93 likes · 1 share · 10,150 followers View post →
Stephen R C
@stephen7778 · X

@grok @randoc3 @MidwesternDoc Hmm. You might want to double check Grok. https://t.co/GbLeEpAbwK

Jun 7, 2025 · 1 like · 246 followers View post →
@CKD_ce
@ckd_ce · X

11) SPRINT: Showed clear #CV benefit ❗ Included #CKD, excluded #T2D

May 28, 2025 · 1 like · 2,636 followers View post →
cardio-met
@cardiomet_CE · X

11) SPRINT: Showed clear #CV benefit ❗ Included #CKD, excluded #T2D

May 28, 2025 · 4,157 followers View post →
よーこ
@YOOCO_223 · X

RT @takua_scientist: 「高血圧の基準は、どんどん下がっているんですよ」 これは事実 「金儲けのためだ!」 これは陰謀論… 単純すぎるのよ。ゆるゆるなのよ。 ↓↓↓実際(の一部)↓↓↓ 2015年 SPRINT試験「血圧120に厳密管理したほうが良くね?…

May 13, 2025 · 13 shares · 748 followers View post →
犬
@toshi_miura · X

RT @takua_scientist: 「高血圧の基準は、どんどん下がっているんですよ」 これは事実 「金儲けのためだ!」 これは陰謀論… 単純すぎるのよ。ゆるゆるなのよ。 ↓↓↓実際(の一部)↓↓↓ 2015年 SPRINT試験「血圧120に厳密管理したほうが良くね?…

May 9, 2025 · 13 shares · 624 followers View post →
みや
@1ch1go1ch1e · X

RT @takua_scientist: 「高血圧の基準は、どんどん下がっているんですよ」 これは事実 「金儲けのためだ!」 これは陰謀論… 単純すぎるのよ。ゆるゆるなのよ。 ↓↓↓実際(の一部)↓↓↓ 2015年 SPRINT試験「血圧120に厳密管理したほうが良くね?…

May 9, 2025 · 13 shares · 3,547 followers View post →
pnanspdx
@pnanspdx95164 · X

RT @takua_scientist: 「高血圧の基準は、どんどん下がっているんですよ」 これは事実 「金儲けのためだ!」 これは陰謀論… 単純すぎるのよ。ゆるゆるなのよ。 ↓↓↓実際(の一部)↓↓↓ 2015年 SPRINT試験「血圧120に厳密管理したほうが良くね?…

May 9, 2025 · 13 shares · 7 followers View post →
avalon1982
@avalon1982 · X

RT @takua_scientist: 「高血圧の基準は、どんどん下がっているんですよ」 これは事実 「金儲けのためだ!」 これは陰謀論… 単純すぎるのよ。ゆるゆるなのよ。 ↓↓↓実際(の一部)↓↓↓ 2015年 SPRINT試験「血圧120に厳密管理したほうが良くね?…

May 9, 2025 · 13 shares · 2,442 followers View post →
海胆の人
@uninohito888 · X

RT @takua_scientist: 「高血圧の基準は、どんどん下がっているんですよ」 これは事実 「金儲けのためだ!」 これは陰謀論… 単純すぎるのよ。ゆるゆるなのよ。 ↓↓↓実際(の一部)↓↓↓ 2015年 SPRINT試験「血圧120に厳密管理したほうが良くね?…

May 9, 2025 · 13 shares · 596 followers View post →
北原 栄(S. Kitahara)
@hLCnTyWQJreYV3G · X

RT @takua_scientist: 「高血圧の基準は、どんどん下がっているんですよ」 これは事実 「金儲けのためだ!」 これは陰謀論… 単純すぎるのよ。ゆるゆるなのよ。 ↓↓↓実際(の一部)↓↓↓ 2015年 SPRINT試験「血圧120に厳密管理したほうが良くね?…

May 9, 2025 · 13 shares · 41 followers View post →
嶋添義久(オタク、薬剤師、危険物取扱者)
@s9Xejr8TFb7gMpz · X

RT @takua_scientist: 「高血圧の基準は、どんどん下がっているんですよ」 これは事実 「金儲けのためだ!」 これは陰謀論… 単純すぎるのよ。ゆるゆるなのよ。 ↓↓↓実際(の一部)↓↓↓ 2015年 SPRINT試験「血圧120に厳密管理したほうが良くね?…

May 9, 2025 · 13 shares · 884 followers View post →
七枝七夏 PPMoPPPMe
@7eda7ca · X

RT @takua_scientist: 「高血圧の基準は、どんどん下がっているんですよ」 これは事実 「金儲けのためだ!」 これは陰謀論… 単純すぎるのよ。ゆるゆるなのよ。 ↓↓↓実際(の一部)↓↓↓ 2015年 SPRINT試験「血圧120に厳密管理したほうが良くね?…

May 9, 2025 · 13 shares · 1,381 followers View post →
Miyuki Chikara
@harugasumi · X

RT @takua_scientist: 「高血圧の基準は、どんどん下がっているんですよ」 これは事実 「金儲けのためだ!」 これは陰謀論… 単純すぎるのよ。ゆるゆるなのよ。 ↓↓↓実際(の一部)↓↓↓ 2015年 SPRINT試験「血圧120に厳密管理したほうが良くね?…

May 8, 2025 · 13 shares · 1,197 followers View post →
血祭謙之介(左党)【愚論極論多事暴論】@エコロジーなエロジジイ
@Eco_Ero_ZZ · X

RT @takua_scientist: 「高血圧の基準は、どんどん下がっているんですよ」 これは事実 「金儲けのためだ!」 これは陰謀論… 単純すぎるのよ。ゆるゆるなのよ。 ↓↓↓実際(の一部)↓↓↓ 2015年 SPRINT試験「血圧120に厳密管理したほうが良くね?…

May 8, 2025 · 13 shares · 910 followers View post →
狢堂主人@富民厚防
@Mujinado · X

RT @takua_scientist: 「高血圧の基準は、どんどん下がっているんですよ」 これは事実 「金儲けのためだ!」 これは陰謀論… 単純すぎるのよ。ゆるゆるなのよ。 ↓↓↓実際(の一部)↓↓↓ 2015年 SPRINT試験「血圧120に厳密管理したほうが良くね?…

May 8, 2025 · 13 shares · 1,038 followers View post →
kazu222z2wka
@kazu222z2wka · X

RT @takua_scientist: 「高血圧の基準は、どんどん下がっているんですよ」 これは事実 「金儲けのためだ!」 これは陰謀論… 単純すぎるのよ。ゆるゆるなのよ。 ↓↓↓実際(の一部)↓↓↓ 2015年 SPRINT試験「血圧120に厳密管理したほうが良くね?…

May 8, 2025 · 13 shares · 2,173 followers View post →
takua フリザード
@takua_scientist · X

「高血圧の基準は、どんどん下がっているんですよ」 これは事実 「金儲けのためだ!」 これは陰謀論… 単純すぎるのよ。ゆるゆるなのよ。 ↓↓↓実際(の一部)↓↓↓ 2015年 SPRINT試験「血圧120に厳密管理したほうが良くね?」 https://t.co/i6Qyw4zztD ↓

May 8, 2025 · 69 likes · 13 shares · 8,415 followers View post →
Kevin Petersen
@PetersenKe10295 · X

@VigilantFox https://t.co/aAlmUaLmAY

Apr 24, 2025 · 1 share · 34 followers View post →
Amy Evan
@Realnea78 · X

RT @Gumby590: @VigilantFox https://t.co/6sWs2To9aE True many measurements are wrong, but there is plenty of evidence that lowering an actu…

Apr 24, 2025 · 1 share · 171 followers View post →
Gumby
@Gumby590 · X

@VigilantFox https://t.co/6sWs2To9aE True many measurements are wrong, but there is plenty of evidence that lowering an actual high blood pressure with meds is associated with fewer CV events, including fatal ones.

Apr 24, 2025 · 3 likes · 1 share · 294 followers View post →
Marc Allard-Ratick
@RatickM · X

@ValerieAnne1970 This was answered in 2015 with a large randomized clinical trial that was funded by the NIH and NOT Big Pharma where lower target BP (120/80) was associated with a reduction in major adverse cardiovascular events. Stop spreading misinformation. https://t.co/zxvfsRPZQf

Mar 16, 2025 · 2 likes · 795 followers View post →
ほどほど
@taka_hiro32 · X

https://t.co/1XqhcYZiQF

Mar 12, 2025 · 858 followers View post →
Riñón Acido
@AcidoRinon · X

@HumMikael @Nefrogeria2024 @galindozip @AryMartnez16 SPRINT-Trial 10.1056/NEJMoa1511939 https://t.co/I7ltAsaYM3

Feb 6, 2025 · 2 likes · 10,150 followers View post →
Oskar
@notoskarisaak · X

@Otonbem Fuente raíz? La mía es https://t.co/MJhsWUhVOm

Jan 31, 2025 · 603 followers View post →
Not Pedro
@notpedropaskal · X

@Otonbem Fuente raíz? La mía es https://t.co/MJhsWUhVOm

Jan 31, 2025 · 639 followers View post →
Deliria Espinosa au Barca
@HijaDLosEspinos · X

RT @notoskarisaak: Concretamente el objetivo <120 disminuyó los eventos CV en un 25% y la mortalidad global en 27%. Así que POR FAVOR dejem…

Jan 31, 2025 · 1 share · 417 followers View post →
Oskar
@notoskarisaak · X

Concretamente el objetivo <120 disminuyó los eventos CV en un 25% y la mortalidad global en 27%. Así que POR FAVOR dejemos de decir a la gente que con PAS 130 mmHg están bien!!! Os dejo el link al estudio SPRINT, que no me lo estoy inventando https://t.co/MJhsWUhVOm

Jan 31, 2025 · 13 likes · 1 share · 603 followers View post →
Not Pedro
@notpedropaskal · X

Concretamente el objetivo <120 disminuyó los eventos CV en un 25% y la mortalidad global en 27%. Así que POR FAVOR dejemos de decir a la gente que con PAS 130 mmHg están bien!!! Os dejo el link al estudio SPRINT, que no me lo estoy inventando https://t.co/MJhsWUhVOm

Jan 31, 2025 · 13 likes · 1 share · 639 followers View post →
Taylor Palfrey
@TaylorPalfrey · X

@svennebananars @JacquiDeevoy1 https://t.co/A6C7aypu79

Jan 30, 2025 · 155 followers View post →
Joe Schmoe
@joeschm80238897 · X

@ValerieAnne1970 Those lousy scientists testing their hypotheses: https://t.co/ANMN03Vwwf

Jan 9, 2025 · 75 followers View post →
Matthew Phares
@pharesFIRE2023 · X

@PierreKory @MidwesternDoc Explain this: https://t.co/9zLsgHzGwX

Nov 26, 2024 · 1 like · 82 followers View post →
Juan Senior
@jsenior64 · X

Lo dijo el SPRINT en pacientes de alto riesgo, según el estudio, en el 2015. https://t.co/cdC8WSJG7Z

Nov 16, 2024 · 11,061 followers View post →
Juan Senior
@jsenior64 · X

@renecardio4 @AHAMeetings Y el que empezó todo y no se le creyó mucho. https://t.co/cdC8WSJG7Z

Nov 16, 2024 · 1 like · 11,061 followers View post →
John P Erwin III MD MBA MACC (#BigPoppy )
@HeartOTXHeartMD · X

RT @SwissHeartDoc: @HeartOTXHeartMD SPRINT trial in the NEJM https://t.co/BJsgLtFOHi

Oct 16, 2024 · 1 share · 39,642 followers View post →
Dr. Sou
@SwissHeartDoc · X

@juneslater17 SPRINT trial in NEJM 2015. Almost 10 years old. https://t.co/BJsgLtFgRK

Oct 16, 2024 · 884 followers View post →
Dr. Sou
@SwissHeartDoc · X

@HeartOTXHeartMD SPRINT trial in the NEJM https://t.co/BJsgLtFOHi

Oct 16, 2024 · 1 like · 1 share · 884 followers View post →
Nephrology Journal Club
@NephJC · X

2/10 What did I miss? Until now studies such as SPRINT (without DM) & ACCORD (with DM), suggested how different populations may benefit differently from intensive BP control. #NephJC SPRINT: https://t.co/isYOAzbIS1 ACCORD: https://t.co/Q3gNS60PxF

Sep 12, 2024 · 38,218 followers View post →
Milagros Flores
@dra_miliflores · X

Recordando SPRINT

Sep 11, 2024 · 1 like · 908 followers View post →
Nephrology Journal Club
@NephJC · X

T0j/

Sep 11, 2024 · 6 likes · 38,218 followers View post →
Nephrology Journal Club
@NephJC · X

T0i/

Sep 11, 2024 · 6 likes · 38,218 followers View post →
Mohamed E. Elrggal
@M_Elraggal · X

RT @NephJC: T0j: #NephJC

Sep 10, 2024 · 1 share · 1,697 followers View post →
Nephrology Journal Club
@NephJC · X

T0j: #NephJC

Sep 10, 2024 · 6 likes · 1 share · 38,218 followers View post →
Swapnil Hiremath @hswapnil.medsky.social
@hswapnil · X

RT @NephJC: T0i/

Sep 10, 2024 · 1 share · 21,703 followers View post →
Nephrology Journal Club
@NephJC · X

T0i/

Sep 10, 2024 · 6 likes · 1 share · 38,218 followers View post →
John Tal
@JohnTal6 · X

RT @JohnTal6: @selberpflegen Empfehlung basiert auf folgender randomisierten Studie: https://t.co/aY76ddyo5x bestätigt übrigens vorherige…

Sep 6, 2024 · 1 share · 675 followers View post →
John Tal
@JohnTal6 · X

@selberpflegen Empfehlung basiert auf folgender randomisierten Studie: https://t.co/aY76ddyo5x bestätigt übrigens vorherige RCT 120 vs 140 mmHg syst https://t.co/qAuS42Q9xK Metaanalyse https://t.co/b6caN0HiUN Sie haben keine Ahnung gute Frau

Sep 6, 2024 · 17 likes · 1 share · 675 followers View post →
Karl Martin Wissing
@kmwissing · X

@JASN_News @gchertow @StanfordNeph @ManjulaKTamura @NMPajewski @PDrawz @taraichang @UofUMedicine The main observation of the original Sprint study was an approximately 25% reduction in MACE and all-cause mortality in the intensive treatment arm (DOI: 10.1056/NEJMoa1511939).

Aug 1, 2024 · 4 followers View post →
Yuri Pride
@yuripridemd · X

@dranulala @m_palsania @DrMarthaGulati @PamTaubMD @ErinMichos @robmentz @QuentinYoumans Haven't we known this for like almost 10 years? https://t.co/JraXS07dHa

Jul 3, 2024 · 3 likes · 3,829 followers View post →
John Tal
@JohnTal6 · X

@TBreitschneider Man muss schon etwas an Verfolgungswahn leiden wenn jegliche wissenschaftliche Erkenntniss sofort in die böse Pharmaecke beschoben wird. Ein niedriger Blutdruck ist nunmal vorteilhaft. Gibt genügend große randomisierte Studien https://t.co/qAuS42Q9xK https://t.co/aY76ddyo5x https://t.co/zWmoeu6s6o

Jun 30, 2024 · 4 likes · 675 followers View post →
HUGO COLOMBO MD
@HCOLOMBO1958 · X

RT @cremieuxrecueil: @EricTopol @TheLancet I don't know what you mean by this being the first trial to target <120 vs <140 mm Hg. ESPRIT st…

Jun 29, 2024 · 1 share · 1,123 followers View post →
Crémieux
@cremieuxrecueil · X

@EricTopol @TheLancet I don't know what you mean by this being the first trial to target <120 vs <140 mm Hg. ESPRIT started years after SPRINT had already targeted <120 vs <140 with practically the same result. https://t.co/KrcOVm3YPe The NHLBI's Expert Panel on a Hypertension Treatment Trial https://t.co/YEi8VQwTi0

Jun 28, 2024 · 10 likes · 1 share · 271,029 followers View post →
Ljubomir Buturovic
@ljbuturovic · X

@EricTopol @TheLancet (for readers not familiar with SPRINT) https://t.co/BlN4Oabk0U

Jun 28, 2024 · 411 followers View post →
Dilushi Wijayaratne
@Dilushiwijay · X

RT @cardiomet_CE: 12c) ... reduces cardiovascular events and mortality in patients with CKD by 25%–30% #VisualGraphic from @Dilushiwijay @N…

May 20, 2024 · 1 share · 1,330 followers View post →
cardio-met
@cardiomet_CE · X

12c) ... reduces cardiovascular events and mortality in patients with CKD by 25%–30% #VisualGraphic from @Dilushiwijay @NephJC #Nephpearls

May 20, 2024 · 3 likes · 1 share · 4,157 followers View post →
Dr. Claudio Moriñigo
@ClaudioMor77620 · X

RT @ckd_ce: 12c) ... reduces cardiovascular events and mortality in patients with CKD by 25%–30% #VisualGraphic from @Dilushiwijay @NephJC…

May 9, 2024 · 1 share · 23 followers View post →
@CKD_ce
@ckd_ce · X

12c) ... reduces cardiovascular events and mortality in patients with CKD by 25%–30% #VisualGraphic from @Dilushiwijay @NephJC #Nephpearls

May 7, 2024 · 4 likes · 1 share · 2,636 followers View post →
HANIBAL'S WORLD OF THE DECEASED
@HupferJan · X

RT @marko_kovic: 7/ Die Änderung der Bluthochdruck-Grenze basiert auf Daten einer grossen randomisierten Studie mit über 9’000 Proband:inne…

May 5, 2024 · 2 shares · 826 followers View post →
Yannik Berger
@YannikBerger2 · X

RT @marko_kovic: 7/ Die Änderung der Bluthochdruck-Grenze basiert auf Daten einer grossen randomisierten Studie mit über 9’000 Proband:inne…

May 5, 2024 · 2 shares · 279 followers View post →
Marko Kovic
@marko_kovic · X

7/ Die Änderung der Bluthochdruck-Grenze basiert auf Daten einer grossen randomisierten Studie mit über 9’000 Proband:innen. Die Änderung gab es also wegen neuer, präziserer Evidenz. Es war nicht einfach eine willkürliche Entscheidung. https://t.co/KSchsk0Et2

May 5, 2024 · 56 likes · 2 shares · 18,400 followers View post →
Revel Peters
@urbanlamb · X

Be Healthier Than 99% of People - Diet principles https://t.co/L0nySkPIxK

Mar 26, 2024 · 109 followers View post →
F. René Pesqueira F.
@rpesquei · X

Estudio reciente: https://t.co/brtyP2ckxj Corrobora que el control estricto de la presión arterial en pacientes hipertensos mejora el pronóstico de complicaciones cardio y cerebrovasculares y ademas el riesgo de padecer demencia.

Nov 13, 2023 · 621 followers View post →
thmonk
@thmonk_pf · X

RT @thmonk_pf: 厳格な収縮期血圧(SBP)降下はGlymphatic system障害を抑制 SPRINT試験(https://t.co/e6RLavmmkt)Sub解析(N=382) SBP<120mmHgの群、Ca拮抗剤服用群はSBP<140mmHgの群と…

Oct 2, 2023 · 1 share · 1,630 followers View post →
thmonk
@thmonk_pf · X

厳格な収縮期血圧(SBP)降下はGlymphatic system障害を抑制 SPRINT試験(https://t.co/e6RLavmmkt)Sub解析(N=382) SBP<120mmHgの群、Ca拮抗剤服用群はSBP<140mmHgの群と比較し4年後のMRIで血管周囲腔体積が有意に減少 Open Access #blood_pressur #glymphatics #papers https://t.co/EZHlEp3dsQ

Oct 2, 2023 · 2 likes · 1 share · 1,630 followers View post →
Farzad Mostashari
@Farzad_MD · X

@ambilinski SPRINT trial was 9,361 patients The intervention was stopped early after a median follow-up of 3.26 years. All-cause mortality was significantly lower in the intensive-blood pressure treatment group (hazard ratio, 0.73; 95% CI, 0.60 to 0.90; P=0.003). https://t.co/N0t6MqBECL

Oct 1, 2023 · 58,250 followers View post →
Paul Forsyth
@PharmacistHF · X

@medicalaxioms It would be great to look at the SPRINT blood pressure trial https://t.co/IKTETGlyfq

Sep 10, 2023 · 3,736 followers View post →
Thomas
@DocteurThomas · X

@Nicolas_C4 @JosephUdeSax @FC_actu https://t.co/CISMsqplDx

Jun 25, 2023 · 3,317 followers View post →
Dr Paddy Barrett
@Paddy_Barrett · X

Some people have very politely (Some not so politely) requested the citations for the video above. For the courteous & curious - happy to share: 1. A Randomized Trial of Intensive versus Standard Blood-Pressure Control. N Engl J Med. 2015 Nov 26;373(22):2103-16. 2. Assessment

Jun 11, 2023 · 11 likes · 55,729 followers View post →
Osmary
@OsmaryAlAr · X

RT @ISNkidneycare: SPRINT study included 40% elderly CKD patients, who had benefitted from strict control of BP? ➡️ More on "A Randomized T…

May 30, 2023 · 3 shares · 359 followers View post →
Jamie Wang
@jamiewang1228 · X

RT @ISNkidneycare: SPRINT study included 40% elderly CKD patients, who had benefitted from strict control of BP? ➡️ More on "A Randomized T…

May 30, 2023 · 3 shares · 9 followers View post →
Baron_Kigume
@KigumeR · X

RT @ISNkidneycare: SPRINT study included 40% elderly CKD patients, who had benefitted from strict control of BP? ➡️ More on "A Randomized T…

May 30, 2023 · 3 shares · 593 followers View post →
Int Society of Nephrology
@ISNkidneycare · X

SPRINT study included 40% elderly CKD patients, who had benefitted from strict control of BP? ➡️ More on "A Randomized Trial of Intensive versus Standard Blood-Pressure Control" at @NEJM https://t.co/rYsiqZfj3K Join us: https://t.co/TOb7gmFwHj

May 30, 2023 · 5 likes · 3 shares · 29,142 followers View post →
Matt Thomas
@DrMattThomas · X

@RichardLehman1 @raj_mehta @sfinnikin @stokemacca Likely every person has their own ideal BP based on their personal circumstances/comorbidities. I wrote a brief presentation on this here: https://t.co/byR6pa7J3o

Apr 24, 2023 · 3 likes · 68 followers View post →
Tomo Takada
@toroeater · X

Dr Attiaが血圧が高すぎないことが大事だと言っていたことを先日のFOREVER23でシェアしました。 たまたま「血圧は心配しなくていい」と言うある先生のビデオを見て下のリサーチ結果をシェアするべきだと思いました。NEJMに載った物でとても信頼度が高い物です。 https://t.co/zYkQomJOpK #ライブラン https://t.co/hOPqSbLYeV

Apr 5, 2023 · 26 likes · 17,985 followers View post →
Abu Shoyeb, MD
@abushoyeb · X

@PeterDiamandis @elonmusk Evidence of SBP >120 is a cumulative slow poisoning effect of excess calories coupled with decreased physical activities ie after homo sapiens abandoned hunter gatherer lifestyle. Agriculture paved the way for mass production of carbs making most modern https://t.co/hDmMnQMFfG https://t.co/ROmsTtvCQA

Mar 29, 2023 · 1 like · 704 followers View post →
Charmaine Aisha Ambatali
@amaineaishaMD · X

RT @uppghnephrology: #VisualAbstract on target blood pressure control among #CKD patients. Learn on the SPRINT

Mar 13, 2023 · 1 share · 563 followers View post →
UP-PGH Nephrology
@uppghnephrology · X

#VisualAbstract on target blood pressure control among #CKD patients. Learn on the SPRINT

Mar 10, 2023 · 1 like · 1 share · 218 followers View post →
.
@AdiG1993 · X

@ImgVasanth @spkalantri https://t.co/3bGF3HKpCw

Dec 6, 2022 · 36,954 followers View post →
Carmen De Miguel, PhD, MS, FAHA
@Carmendemigue12 · X

RT @georgehret: #HYPHIP Q2: Can you remind us of the two treatment groups in #SPRINT https://t.co/gpMHVIYhxV and the main results please?…

Dec 5, 2022 · 4 shares · 3,341 followers View post →
Tanja Dudenbostel, MD, FASH, FAHA
@DrDudenbostel · X

RT @georgehret: #HYPHIP Q2: Can you remind us of the two treatment groups in #SPRINT https://t.co/gpMHVIYhxV and the main results please?…

Dec 5, 2022 · 4 shares · 1,498 followers View post →
Hypertension
@HyperAHA · X

RT @georgehret: #HYPHIP Q2: Can you remind us of the two treatment groups in #SPRINT https://t.co/gpMHVIYhxV and the main results please?…

Dec 5, 2022 · 4 shares · 10,664 followers View post →
Guto Montezano
@guto_montezano · X

RT @georgehret: #HYPHIP Q2: Can you remind us of the two treatment groups in #SPRINT https://t.co/gpMHVIYhxV and the main results please?…

Dec 5, 2022 · 4 shares · 1,312 followers View post →
Georg Ehret, MD FESC FAHA
@georgehret · X

#HYPHIP Q2: Can you remind us of the two treatment groups in #SPRINT https://t.co/gpMHVIYhxV and the main results please? @wccushman @HyperAHA

Dec 5, 2022 · 6 likes · 4 shares · 939 followers View post →
Jahir Rodríguez - Rivera
@j_rdzrivera · X

Referencias: - Jaeger, et al. (2022) JAMA cardiology, DOI: 10.1001/jamacardio.2022.3345 - SPRINT Research Group, (2015). NEJM 373(22), 2103–2116. DOI: 10.1056/NEJMoa1511939 #CardioEd #MedTwitter

Oct 14, 2022 · 41 followers View post →
Florence Healthcare
@FlorenceHCare · X

The SPRINT blood pressure trial provides a great example of how community-based clinical trials can work. Their outreach to community sites allowed them to recruit 15,000 participants, more than their goal, and 50% of those patients were people of color. https://t.co/OfHyrvUKRA

Aug 18, 2022 · 1 like · 921 followers View post →
Landmark Trials
@LandmarkTrials · X

Read the original study here: https://t.co/MBNKkUJtSI

Jul 31, 2022 · 3 likes · 850 followers View post →
Swapnil Hiremath @hswapnil.medsky.social
@hswapnil · X

RT @amjhypertension: Certain groups made that into a big deal, eg https://t.co/JPbCVtNgyp and https://t.co/4g8qT0weoP 3/ https://t.co/6zeX…

Jul 28, 2022 · 1 share · 21,703 followers View post →
Swapnil Hiremath @hswapnil.medsky.social
@hswapnil · X

RT @amjhypertension: Why does this matter? Famously, in the SPRINT trial, BP was *planned* to be measured with the patient being alone http…

Jul 27, 2022 · 1 share · 21,703 followers View post →
American Journal of Hypertension
@amjhypertension · X

Certain groups made that into a big deal, eg https://t.co/JPbCVtNgyp and https://t.co/4g8qT0weoP 3/ https://t.co/6zeXoRD62A

Jul 26, 2022 · 1 like · 1 share · 1,274 followers View post →
American Journal of Hypertension
@amjhypertension · X

Why does this matter? Famously, in the SPRINT trial, BP was *planned* to be measured with the patient being alone https://t.co/EQC6eL0o9D See #NephMadness coverage of this as well https://t.co/RQfPlb0alF 2/

Jul 26, 2022 · 4 likes · 1 share · 1,274 followers View post →
Carmen Cajina
@CajinaCarmen · X

RT @NephJC: T0c: In the

Apr 23, 2022 · 6 shares · 1,175 followers View post →
Igor Parada
@MarangoniMD · X

Available in: https://t.co/FJ4mJSenbt

Mar 7, 2022 · 13 followers View post →
Igor Parada
@MarangoniMD · X

I read this weekend a terrific article from @NEJM, “A Randomized Trial of Intensive versus Standard Blood-Pressure Control.” The conclusion was that an intensive blood pressure reduction decreased adverse cardiovascular outcomes compared with standard blood pressure treatment. https://t.co/lh0o1w1lMc

Mar 7, 2022 · 1 like · 13 followers View post →
Florian Custodis
@floriancustodis · X

RT @gunnar_heine: Zielblutwerte bei Risikopatienten - STEP - Prof. Mann (München) https://t.co/ZyDjHkgqw0 via @YouTube jz online

Nov 12, 2021 · 1 share · 751 followers View post →
Gunnar Henrik Heine
@gunnar_heine · X

Zielblutwerte bei Risikopatienten - STEP - Prof. Mann (München) https://t.co/ZyDjHkgqw0 via @YouTube jz online

Nov 12, 2021 · 1 like · 1 share · 2,325 followers View post →
Florian Custodis
@floriancustodis · X

RT @gunnar_heine: Zielblutwerte bei Risikopatienten - STEP - Prof. Mann (München) https://t.co/ZyDjHkgqw0 via @YouTube Morgen 12.11. 19:30!

Nov 12, 2021 · 1 share · 751 followers View post →
Gunnar Henrik Heine
@gunnar_heine · X

Zielblutwerte bei Risikopatienten - STEP - Prof. Mann (München) https://t.co/ZyDjHkgqw0 via @YouTube Morgen 12.11. 19:30!

Nov 11, 2021 · 2 likes · 1 share · 2,325 followers View post →
GoalsOfHair
@GoalsOfHair · X

@EM_RESUS I’m sorry. Did you say chlorthalidone? https://t.co/NfaxZYDK1d #sprint @nih_nhlbi @NIDDKgov

Oct 16, 2021 · 104 followers View post →
Eric Widera, MD
@EWidera · X

@macesari Hard not to think about SPRINT as it was a game changer and went against a less is more mantra https://t.co/tdewU3tDXK

Oct 2, 2021 · 6 likes · 15,120 followers View post →
cardio-met
@cardiomet_CE · X

This trial was designed to understand the optimal BP targets to reduce CV mortality and morbidity (in those without diabetes)…https://t.co/LA1bb5vZAF

Sep 10, 2021 · 3 likes · 4,157 followers View post →
Paul Forsyth
@PharmacistHF · X

@nuri__karakaya @escardio Builds on the findings of the previous SPRINT trial https://t.co/IKTETGlyfq

Aug 30, 2021 · 3,736 followers View post →
Nephrology Journal Club
@NephJC · X

9:08 T0c: In the

Jun 9, 2021 · 4 likes · 1 share · 38,218 followers View post →
Urmila Anandh
@AnandhUrmila · X

RT @NephJC: T0c: In the

Jun 9, 2021 · 6 shares · 4,012 followers View post →
Abhishek
@aksrulz13 · X

RT @NephJC: T0c: In the

Jun 8, 2021 · 6 shares · 623 followers View post →
John P Erwin III MD MBA MACC (#BigPoppy )
@HeartOTXHeartMD · X

RT @NephJC: T0c: In the

Jun 8, 2021 · 6 shares · 39,642 followers View post →
Fitsum Asnakech Tilahun MD , FASN
@fitse_t · X

RT @NephJC: T0c: In the

Jun 8, 2021 · 6 shares · 21,914 followers View post →
Nephrology Journal Club
@NephJC · X

T0c: In the

Jun 8, 2021 · 17 likes · 6 shares · 38,218 followers View post →
Tá de Clinicagem - TdC
@tadeclinicagem · X

Essas orientações são mais antigas do que o estudo SPRINT, referência para a AHA/ACC. A diretriz de 2017 aponta como ideal PA < 130 x 80 (não foram incluídos diabéticos). Esse alvo diminuiu desfechos cardiovasculares e morte, inclusive no grupo com DRC. https://t.co/xptUOBX1lM

May 21, 2021 · 4 likes · 12,005 followers View post →
Juan Senior
@jsenior64 · X

En el estudio SPRINT se demostró beneficios en lograr metas más estrictas, con impacto en mortalidad, sin embargo el número de eventos no permite establecer diferencias en otros desenlaces individuales. https://t.co/YjjzdJLL6e

Mar 27, 2021 · 2 likes · 11,061 followers View post →
Carlos
@CertainlyCarlos · X

@BaeBielle Measuring improperly is always wrong, but they may be drawing from SPRINT’s writeup here. “Observational studies have shown a progressive increase in cardiovascular risk as systolic blood pressure rises above 115 mm Hg” https://t.co/mPTzFf0iaZ

Feb 13, 2021 · 36 followers View post →
U. Annone
@ABertu6 · X

@carlogubi Quasi nessun trial è open, per diversi motivi anche di privacy; forse l’unico è lo SPRINT (https://t.co/gwMHZp6082). Per questo esiste il sistema di peer review.

Dec 9, 2020 · 1 like · 269 followers View post →
Harmless Frog
@FrogHarmless · X

More intensive hypertension management helps more. https://t.co/8RtfgKwkD3

Nov 20, 2020 · 504 followers View post →
psychetrick
@psychetrick · X

RT @HenryRunamucker: Claims of efficacy are extremely dubious. The trial ends with only 34 participants out of more than 100. Most well-con…

Nov 14, 2020 · 1 share · 1,723 followers View post →
Bert
@HenryRunamucker · X

Claims of efficacy are extremely dubious. The trial ends with only 34 participants out of more than 100. Most well-conducted modern trials to determine efficacy of medical treatments have thousands of participants. See this trial, for example: https://t.co/5DFGr2jW5V

Nov 11, 2020 · 31 likes · 1 share · 2,125 followers View post →
J. Brian Byrd Lab
@thebyrdlab · X

RT @RebeccaEBerger: @thebyrdlab Probably not what you are looking for, but in SPRINT, mean number of BP medications was 2.8 in intensive-tr…

Nov 8, 2020 · 1 share · 4,604 followers View post →
Rebecca Berger
@RebeccaEBerger · X

@thebyrdlab Probably not what you are looking for, but in SPRINT, mean number of BP medications was 2.8 in intensive-treatment group and 1.8 in standard-treatment group https://t.co/sRjsu6fq9H

Nov 8, 2020 · 4 likes · 1 share · 3,669 followers View post →
Gray Wolf
@GreyWol27926578 · X

RT @jwilliamMD: #TullisFC this week! ⁦@marybethhamel⁩, Exec Deputy Editor of ⁦@NEJM⁩ and ⁦@BIDMChealth⁩ PCP, will walk us through the criti…

May 22, 2020 · 3 shares · 164 followers View post →
Damian Fogarty
@DamianFog · X

@emmylou_breslin @clo13 @DrGerryG @CarryduffS @ursulaamason @Drbmcg @fillharmonica @davinacassidy @DrAndreaMurray @nigelhart @mcentee_siobhan @MARIAMONAGHAN9 @PeterBoylan2 @andre_harper @NiamhMcCormick9 @LINDAAGNEW12 @CSHenderson88 @monica_mckillen @WestBelfastGP @GpBelfast @gp_northern @EasternGp @GPTrainingNI @_NIMDTA @gpsouthbelfast @gpfed_derry Meant to include more on blood pressure targets both in general populations & with any signs of CKD. As a starter here’s a great video on the #SPRINT study’s main findings supporting lower targets. 2 minute view. https://t.co/mDoFnxVyE8

May 14, 2020 · 5 likes · 7,963 followers View post →
Bob Smithers MD
@DoctorSkeptical · X

@KurtLass1 @holmanm Sprint trial showed mortality benefit treating to <120 sbp https://t.co/oUe1y3yeT2

Mar 28, 2020 · 469 followers View post →
Michael Dike
@mykel_d · X

Intensive blood pressure control (#SBP target of <120mmHg, compared with 140 mmHg) results in reduced incidence of fatal and non-fatal major adverse cardiovascular events and all-cause mortality. #SPRINT study. https://t.co/ieEfLy8FLZ

Feb 14, 2020 · 3 likes · 87 followers View post →
Apache M
@daktarirubani · X

https://t.co/TITGQqhaQA @zaidkadwa @KursheedBadulla @RONALD41077142 @the_mc_muga @NelsonMweteri Intensive BP control w/ target 120/80mmHg reduced OR 0.75 all-cause mortality and CV related deaths

Jan 26, 2020 · 147 followers View post →
RONALD LUKE
@RONALD41077142 · X

Interesting, those without #Diabetes should have lower #BP goals. #Hypertension. The #SPRINT trial.

Jan 25, 2020 · 16 followers View post →
Rocky Mountain Center for Occ. and Env. Health
@UofUOEH · X

Our first Journal Club of 2020 is today at noon! Drs. Hans Schwertz and Brent Shepherd will be presenting on jugular venous blood flow stasis and thrombosis during spaceflight and a randomized trial of intensive versus standard blood pressure control. https://t.co/OE4DoIdQb0

Jan 10, 2020 · 2 likes · 126 followers View post →
J. Brian Byrd Lab
@thebyrdlab · X

@MWFriedberg @rajesh_mohandas @boback @brzoskos Clinical trials are research experiments & will not look like today's practice in most instances No reason to suspect harm in the opinion of lots of hypertension experts not involved in the study Protocol available since time of publication https://t.co/RBkrWl8YR2

Jan 2, 2020 · 2 likes · 4,604 followers View post →
Bess_Flashner
@bess_flashner · X

RT @jwilliamMD: #TullisFC this week! ⁦@marybethhamel⁩, Exec Deputy Editor of ⁦@NEJM⁩ and ⁦@BIDMChealth⁩ PCP, will walk us through the criti…

Dec 13, 2019 · 3 shares · 269 followers View post →
pinacol
@pinacol · X

A Randomized Trial of Intensive versus Standard Blood-Pressure Control. https://t.co/G5iVHfncMy #jsphcs2019

Nov 3, 2019 · 1 like · 1 share · 1,611 followers View post →
Ricardo Cedeno-Mendoza, MD, AAHIVS
@ricardocedenomd · X

Check out The SPRINT Research Group: A Randomized Trial of Intensive versus Standard Blood-Pressure Control https://t.co/em3MNKugrR

Mar 25, 2019 · 559 followers View post →
Francisca Martínez
@famartinez2001 · X

RT @carprimur: Desde hace unos años, @nejm nos brinda estos excepcionales vídeos resumen de los principales estudios. Aquí tenéis el del e…

Mar 18, 2019 · 1 share · 9,951 followers View post →