Mitohormesis in exercise training.

Abstract in brief

• Mitohormesis is a process where low levels of stress, like during exercise, trigger the mitochondria to send signals to the cell nucleus, promoting adaptive changes that improve how the cell handles future stress.
• The concept suggests that mitochondria can initiate a response to disturbances caused by exercise, leading to both mitochondrial and overall cell improvements, especially through signals like reactive oxygen species (ROS).
• Although direct studies are limited, evidence indicates mitochondrial signals during exercise could activate genes related to mitochondrial growth and function, playing a key role in the beneficial adaptations from exercise training.]