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J Neurogastroenterol Motil April 2016 PMID 26755686

Mast Cells and Irritable Bowel Syndrome: From the Bench to the Bedside.

Lei Zhang, Jun Song, Xiaohua Hou

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Mentions

7
Peak: 2 in Mar 2025
across 4 sources since May 2019

Extended reach

5,972
potential audience

Total likes

54

Video views

1,445

Mentions per month

May 2019 – Mar 2025

Where it's discussed

  • News3 articles
  • YouTube2 videos
  • X / Twitter1 posts
  • Reddit1 posts

AI synopsis

What people are saying

The discussion illustrates an interest in the molecular mechanisms of IBS, highlighted by phrases like 'Listening now to Mast Cell Activation' and questions about symptoms, suggesting curiosity about recent research developments. The tone is reflective and slightly surprised, indicating that new insights may alter previous beliefs or clinical approaches.

AgreementModerate agreement

The poster seems to agree or at least relate to the content, questioning previous assumptions about IBS.

InterestModerate interest

The discussion indicates moderate curiosity about the topic, especially the immediate GI symptoms after eating.

EngagementModerate engagement

There is some engagement with the subject, as the poster reflects on their own understanding and calls out to an expert.

ImpactModerate impact

While the discussion shows relevance, it doesn't suggest a profound change in perspective or extensive influence.

Abstract in brief

  • Mast cells are increasingly linked to irritable bowel syndrome (IBS), a disorder previously thought to lack physical abnormalities, as studies show they can be involved in inflammation, mucosal barrier problems, and hypersensitivity in the gut.
  • Research focuses on how mast cells develop, activate, and affect intestinal functions like secretion, immune response, and nerve signaling, which contribute to IBS symptoms such as pain and irregular bowel movements.
  • Treatments targeting mast cells, including stabilizers and receptor antagonists, have shown some success in easing IBS symptoms, and recent studies aim to connect these scientific findings with better clinical therapies.]
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Top posts

Most liked on X and Bluesky
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@mamagastra · X

Listening now to Mast Cell Activation by Dr Nathan GI Symptoms occur immediately after eating even water It’s not allergy (I hear this all the time) Have I been missing this all along? Calling this IBS @DrDeborahFisher https://t.co/YljxTSGJr5

May 5, 2019 · 4,488 followers View post →

All mentions

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@mamagastra · X

Listening now to Mast Cell Activation by Dr Nathan GI Symptoms occur immediately after eating even water It’s not allergy (I hear this all the time) Have I been missing this all along? Calling this IBS @DrDeborahFisher https://t.co/YljxTSGJr5

May 5, 2019 · 4,488 followers View post →
Mast Cell Stabilizer - Wikipedia | PDF | Allergy | Immunology
News

doi:10.5056/jnm15137 . PMC 4819856 . PMID 26755686 . 7. ^ Nwaru BI, Dhami S, Sheikh A (2017). "Idiopathic Anaphylaxis" . Curr Treat Options Allergy. 4 (3):

Dec 17, 2025 View →
Takeshi Kamiya Irritable Bowel Syndrome 2024 | PDF | Irritable ...
News

https://doi.org/10.5056/jnm15137. PubMed PMID: 26755686; PubMed Central PMCID: PMCPMC4819856. 60. Bischoff SC, Kramer S. Human mast cells, bacteria, and ...

Dec 17, 2025 View →
Irritable Bowel Syndrome With Diarrhea Treatment Is A Work in ...
News

doi:10.5056/jnm15137 symptoms. Dig Dis Sci 2016; 61(2):560–571. 40. Cremon C, Stanghellini V, Barbaro MR, et al. Randomised clinical doi:10.1007/s10620-015 ...

Dec 17, 2025 View →
Cromulyn sodium? : r/EGID
Reddit

Mast Cells and Irritable Bowel Syndrome: From the Bench to the Bedside. J Neurogastroenterol Motil. 2016;22(2):181-192. doi:10.5056/jnm15137.

Oct 8, 2024 View →