March 2016 PMID 26775730

The Wnt signaling pathway in cancer.

Yann Duchartre, Yong-Mi Kim, Michael Kahn

Mentions

11
Peak: 6 in Jul 2019
across 2 sources since Mar 2019

Extended reach

31,075
potential audience

Total likes

22

Video views

408

Mentions per month

Mar 2019 – Sep 2025

Where it's discussed

  • X / Twitter10 posts
  • YouTube1 videos

AI synopsis

What people are saying

The collection reveals a high level of interest and engagement, with mentions of specific studies like Metformin as an inhibitor and discussions on the pathway's role in drug resistance, demonstrating the community's focus on therapeutic advances. The tone varies from informative summaries to speculative optimism about future applications, underpinning the perceived high impact of these developments.

AgreementModerate agreement

Most discussions acknowledge the importance of Wnt signaling in cancer, with some referencing therapeutic potential and recent research advances, indicating general consensus on its significance.

InterestHigh interest

Posts demonstrate high interest, highlighting novel inhibitors like Metformin and potential drug development avenues, reflecting curiosity and engagement with cutting-edge research.

EngagementModerate engagement

Several posts delve into complex topics such as cancer stem cells, drug resistance mechanisms, and specific molecular interactions, suggesting deep engagement.

ImpactHigh impact

The discussions emphasize the promising outlook of targeting the Wnt pathway for treatments and the significance of recent findings for cancer therapy, indicating high perceived impact.

Abstract in brief

  • The Wnt signaling pathway plays a crucial role in tissue development and maintaining normal stem cells, but abnormal Wnt activity is linked to cancer development and progression.
  • Cancer stem cells (CSCs), which are responsible for tumor formation and relapse, often exhibit drug resistance and are influenced by the Wnt pathway, making them a key target for cancer therapy.
  • Developing treatments that effectively target the Wnt pathway in CSCs without harming normal stem cells remains a challenge, but recent therapeutic strategies and clinical applications are promising in the fight against cancer.

Top posts

Most liked on X and Bluesky
SU2Cscience
@SU2Cscience · X

Dr. David Tuveson, a member of the @SU2C Scientific Advisory Committee, published a summary of a Banbury Center meeting in Science Signaling, discussing the future of the role of the Wnt signaling pathway in cancer research https://t.co/KaEdI2X2aj

Jul 17, 2019 · 15 likes · 5 shares · 2,079 followers View post →
Martín Lázaro
@mlazqui · X

Metformin: A New Inhibitor of the Wnt Signaling Pathway in Cancer - PubMed https://t.co/grVb0fuCuV

Sep 8, 2023 · 1 like · 1 share · 4,230 followers View post →
Let's Win Pancreatic Cancer
@letswinpc · X

RT @SU2Cscience: Dr. David Tuveson, a member of the @SU2C Scientific Advisory Committee, published a summary of a Banbury Center meeting in…

Jul 17, 2019 · 5 shares · 8,063 followers View post →
Lustgarten Foundation
@lustgartenfdn · X

RT @SU2Cscience: Dr. David Tuveson, a member of the @SU2C Scientific Advisory Committee, published a summary of a Banbury Center meeting in…

Jul 18, 2019 · 5 shares · 7,962 followers View post →
Carlos
@MarvinHarris76 · X

RT @mlazqui: Metformin: A New Inhibitor of the Wnt Signaling Pathway in Cancer - PubMed https://t.co/grVb0fuCuV

Sep 14, 2023 · 1 share · 4,518 followers View post →
OurWarOnCancer
@OurWarOnCancer · X

RT @SU2Cscience: Dr. David Tuveson, a member of the @SU2C Scientific Advisory Committee, published a summary of a Banbury Center meeting in…

Jul 17, 2019 · 5 shares · 2,219 followers View post →

All mentions

Carlos
@MarvinHarris76 · X

RT @mlazqui: Metformin: A New Inhibitor of the Wnt Signaling Pathway in Cancer - PubMed https://t.co/grVb0fuCuV

Sep 14, 2023 · 1 share · 4,518 followers View post →
Martín Lázaro
@mlazqui · X

Metformin: A New Inhibitor of the Wnt Signaling Pathway in Cancer - PubMed https://t.co/grVb0fuCuV

Sep 8, 2023 · 1 like · 1 share · 4,230 followers View post →
Documents Delivered, LLC
@DocsDel · X

The role of the Wnt signaling pathway in cancer stem cells: prospects for drug development https://t.co/EDdVgoCGoO

Jun 17, 2021 · 175 followers View post →
Lustgarten Foundation
@lustgartenfdn · X

RT @SU2Cscience: Dr. David Tuveson, a member of the @SU2C Scientific Advisory Committee, published a summary of a Banbury Center meeting in…

Jul 18, 2019 · 5 shares · 7,962 followers View post →
OurWarOnCancer
@OurWarOnCancer · X

RT @SU2Cscience: Dr. David Tuveson, a member of the @SU2C Scientific Advisory Committee, published a summary of a Banbury Center meeting in…

Jul 17, 2019 · 5 shares · 2,219 followers View post →
Sunrise Relay
@rflsunrise · X

RT @SU2Cscience: Dr. David Tuveson, a member of the @SU2C Scientific Advisory Committee, published a summary of a Banbury Center meeting in…

Jul 17, 2019 · 5 shares · 170 followers View post →
Let's Win Pancreatic Cancer
@letswinpc · X

RT @SU2Cscience: Dr. David Tuveson, a member of the @SU2C Scientific Advisory Committee, published a summary of a Banbury Center meeting in…

Jul 17, 2019 · 5 shares · 8,063 followers View post →
Kalpana Pandey
@PINKEY1stMAY · X

RT @SU2Cscience: Dr. David Tuveson, a member of the @SU2C Scientific Advisory Committee, published a summary of a Banbury Center meeting in…

Jul 17, 2019 · 5 shares · 1,089 followers View post →
SU2Cscience
@SU2Cscience · X

Dr. David Tuveson, a member of the @SU2C Scientific Advisory Committee, published a summary of a Banbury Center meeting in Science Signaling, discussing the future of the role of the Wnt signaling pathway in cancer research https://t.co/KaEdI2X2aj

Jul 17, 2019 · 15 likes · 5 shares · 2,079 followers View post →
Journals ZJU
@JournalsZju · X

BM-MSCs enhance the chemoresistance of ovarian cancer by releasing miR-1180.The released miR-1180 activates the wnt signaling pathway in cancer cells by targeting SFRP1.The enhanced wnt signaling upregulates the glycolytic level, which reinforces the… https://t.co/KgLL5MohiR https://t.co/Yc97lszRN3

Mar 5, 2019 · 98 followers View post →