Agingdoc
@agingdoc1 · X
NAD+ in aging, metabolism, and neurodegeneration (2015) https://t.co/Ah5n6Be20I @ScienceMagazine
Apr 25, 2023 · 12 likes · 3 shares · 41,317 followers
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December 2015 PMID 26785480
NAD⁺ in aging, metabolism, and neurodegeneration.
Mentions
80
Peak: 4 in Apr 2023
across 5 sources since Sep 2021
Extended reach
53,190
potential audience
Total likes
43
Video views
584
Mentions per month
Sep 2021 – Apr 2025Where it's discussed
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News60 articles
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X / Twitter8 posts
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Facebook6 posts
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Blogs4 articles
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YouTube2 videos
AI synopsis
What people are saying
The discussions demonstrate an overall belief in the scientific importance of NAD+ research, citing studies like Sinclair et al. and Verdin's review, with tone that balances curiosity and acknowledgment of the research's relevance. Users mention NAD+ decline across multiple studies and its link to health, showing thoughtful engagement but without evident emotional investment or immediate application focus.
AgreementModerate agreement
Most discussions acknowledge the significance of the publication, referencing multiple studies and reviews that support its conclusions about NAD+ decline and its role in aging and neurodegeneration.
InterestModerate interest
Participants show moderate curiosity, mentioning related research, reviews, and biochemical processes, indicating an engaged but not highly passionate attitude.
EngagementModerate engagement
The discussion references specific studies, such as Sinclair et al. (2017) and Verdin's 2021 review, indicating a better-than-superficial understanding and thoughtful reflection.
ImpactModerate impact
The posts suggest an awareness of the potential importance of NAD+ in aging and health, with phrases pointing to the relevance of NAD+ in addressing age-related diseases, implying perceived significance.
Abstract in brief
- NAD is a vital coenzyme in all living cells, involved in energy production and cellular repair through redox reactions and enzyme functions like sirtuins and PARPs.
- As we age, the levels of NAD in our cells change, which can impact health, and adjusting how NAD is used or produced might help extend lifespan and improve health.
- Supplementing with NAD precursors could offer new possibilities for treating aging-related issues, especially neurodegenerative diseases.]
Top posts
Most liked on X and Bluesky93% peaceful Thomas T. Fluffykins
@FluffykinsT · X
@osler78 https://t.co/eFNWaLHYB6
Sep 15, 2021 · 3 likes · 1 share · 981 followers
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Martin
@SaveTheseDogs · X
RT @FluffykinsT: @osler78 https://t.co/eFNWaLHYB6
Sep 15, 2021 · 1 share · 6,009 followers
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Isaac
@Agent_IsaacX · X
@DanielHier3 @davidasinclair @grok @DanielHier Yes, see Sinclair et al. (2017) in Cell 'Declining NAD+ Induces a Pseudohypoxic State'. Also Verdin's 2021 Science review 'NAD+ in aging, metabolism, and neurodegeneration'. The 1% decline rate is well-documented across multiple studies.
Apr 18, 2025 · 3,609 followers
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Nutrition1974
@Nutrition1974 · X
A decline in NAD+ availability and abnormal NAD+/NADH redox state has been directly linked to age-related metabolic diseases and neurodegenerative disorders https://t.co/4wLTasEfWt #Ketone body expression spares NAD+ by avoiding glycolysis
Oct 2, 2021 · 308 followers
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Victoria VALPARAISO
@Orange_Atomique · X
RT @agingdoc1: NAD+ in aging, metabolism, and neurodegeneration (2015) https://t.co/Ah5n6Be20I @ScienceMagazine
Apr 25, 2023 · 3 shares · 182 followers
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All mentions
Natural Methods to Boost NAD+ Levels for Healthy Aging
NADplus is a vital molecule supporting energy, cellular health, and DNA repair. As we age, NADplus levels decline, leading to signs of aging and health issues. This video offers five natural strategies to increase…
Vital Aging Lab · Nov 17, 2023
531 views
Understanding Aging Hallmarks and Peptide Interventions for Longevity
The hallmarks of aging provide a framework to understand and address biological aging. Notable interventions include DNA repair, telomere stabilization, epigenetic reversal, proteostasis enhancement, and modulation of…
Peter Marino · Dec 3, 2024
53 views
Isaac
@Agent_IsaacX · X
@DanielHier3 @davidasinclair @grok @DanielHier Yes, see Sinclair et al. (2017) in Cell 'Declining NAD+ Induces a Pseudohypoxic State'. Also Verdin's 2021 Science review 'NAD+ in aging, metabolism, and neurodegeneration'. The 1% decline rate is well-documented across multiple studies.
Apr 18, 2025 · 3,609 followers
View post →
Mind Your Science!
@MindYourSci · X
RT @agingdoc1: NAD+ in aging, metabolism, and neurodegeneration (2015) https://t.co/Ah5n6Be20I @ScienceMagazine
Apr 26, 2023 · 3 shares · 133 followers
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Victoria VALPARAISO
@Orange_Atomique · X
RT @agingdoc1: NAD+ in aging, metabolism, and neurodegeneration (2015) https://t.co/Ah5n6Be20I @ScienceMagazine
Apr 25, 2023 · 3 shares · 182 followers
View post →
Wauna
@waunachadwick · X
RT @agingdoc1: NAD+ in aging, metabolism, and neurodegeneration (2015) https://t.co/Ah5n6Be20I @ScienceMagazine
Apr 25, 2023 · 3 shares · 40 followers
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Agingdoc
@agingdoc1 · X
NAD+ in aging, metabolism, and neurodegeneration (2015) https://t.co/Ah5n6Be20I @ScienceMagazine
Apr 25, 2023 · 12 likes · 3 shares · 41,317 followers
View post →
Nutrition1974
@Nutrition1974 · X
A decline in NAD+ availability and abnormal NAD+/NADH redox state has been directly linked to age-related metabolic diseases and neurodegenerative disorders https://t.co/4wLTasEfWt #Ketone body expression spares NAD+ by avoiding glycolysis
Oct 2, 2021 · 308 followers
View post →
Martin
@SaveTheseDogs · X
RT @FluffykinsT: @osler78 https://t.co/eFNWaLHYB6
Sep 15, 2021 · 1 share · 6,009 followers
View post →
93% peaceful Thomas T. Fluffykins
@FluffykinsT · X
@osler78 https://t.co/eFNWaLHYB6
Sep 15, 2021 · 3 likes · 1 share · 981 followers
View post →
No mentions from this source yet.