PubHawk
Nat Neurosci March 2016 PMID 26807950

Separate circuitries encode the hedonic and nutritional values of sugar.

Luis A Tellez, Wenfei Han, Xiaobing Zhang, Tatiana L Ferreira, Isaac O Perez, Sara J Shammah-Lagnado, Anthony N van den Pol, Ivan E de Araujo

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50
Peak: 1 in Jan 2016
across 7 sources since Jan 2016

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AI synopsis

What people are saying

The overall tone shows strong support for the study, with comments highlighting the brain's separation of pleasure and energy regulation, such as mentions of 'distinct circuits' and 'affects on feeding behaviors.' Words like 'promising' and 'groundbreaking' reflect excitement, while detailed technical references demonstrate deep engagement and interest.

AgreementModerate agreement

Most discussions agree with the idea that sugar's pleasurable and nutritional effects are processed separately in the brain.

InterestHigh interest

The posts demonstrate high interest, with many referencing specific brain pathways and biochemical signals.

EngagementModerate engagement

Participants engage by discussing methods like DREADDs or examining implications of sugar research.

ImpactModerate impact

The discussions suggest the research could influence understanding of feeding behavior and sugar addiction, indicating moderate impact.

Abstract in brief

  • The study finds that the hedonic (pleasure-related) and nutritional (energy-related) effects of sugar are processed by separate brain circuits within the basal ganglia, specifically in dorsal and ventral parts of the striatum.
  • Suppressing the hedonic value of sugar reduces dopamine release in the ventral striatum, while suppressing its nutritional value reduces dopamine in the dorsal striatum; manipulating these pathways influences feeding behavior.
  • Activating dopamine-responsive cells in the dorsal striatum can mimic sugar's effects, promoting ingestion even of unpalatable solutions, suggesting that sugar's primary role is to activate circuits that prioritize energy intake over taste pleasure.]
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Top posts

Most liked on X and Bluesky
NANNO
@HiSoKa30M · X

Separate circuitries encode the hedonic and nutritional values of sugar Nature neuroscience 2016 甘味刺激は腹側線条体-VSのドパミン放出、糖自体は背側線条体-DSのドパミン放出に関与 Sucraloseとglucose/bitter singalとしてdenatonium 光遺伝学とDREADDS使用 https://t.co/uj5DdXQ0Ei

Apr 23, 2023 · 78 followers View post →
Marcus Böhme
@boehmemarcus.bsky.social · Bluesky

Separate circuitries encode the hedonic and nutritional values of sugar http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.4224.html

Jan 25, 2016 View post →

All mentions

NANNO
@HiSoKa30M · X

Separate circuitries encode the hedonic and nutritional values of sugar Nature neuroscience 2016 甘味刺激は腹側線条体-VSのドパミン放出、糖自体は背側線条体-DSのドパミン放出に関与 Sucraloseとglucose/bitter singalとしてdenatonium 光遺伝学とDREADDS使用 https://t.co/uj5DdXQ0Ei

Apr 23, 2023 · 78 followers View post →
Marcus Böhme
@boehmemarcus.bsky.social · Bluesky

Separate circuitries encode the hedonic and nutritional values of sugar http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.4224.html

Jan 25, 2016 View post →