Oral Dis September 2016 PMID 26808119

Vitamin C: the known and the unknown and Goldilocks.

S J Padayatty, M Levine

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Mentions

37
Peak: 8 in Nov 2020
across 5 sources since Mar 2020

Extended reach

4,054,569
potential audience

Total likes

101,053

Video views

3,780,228

Mentions per month

Mar 2020 – Apr 2025

Where it's discussed

  • X / Twitter19 posts
  • News8 articles
  • YouTube6 videos
  • Facebook2 posts
  • Blogs2 articles

AI synopsis

What people are saying

Several posts explore the biochemical role of vitamin C as an electron donor and enzyme cofactor, illustrating interest in its physiological functions. Others debate the effectiveness of high-dose supplements, referencing bioavailability data and encouraging focus on food sources, which demonstrates a balanced yet inquisitive engagement with the research findings.

AgreementModerate agreement

Most discussions acknowledge the scientific information about vitamin C's biological functions, though some question its efficacy in high doses.

InterestModerate interest

Participants show moderate interest, engaging in detailed explanations about bioavailability and dietary sources rather than superficial mentions.

EngagementModerate engagement

Posts include technical details, references to research studies, and debates over supplement effectiveness, indicating meaningful involvement.

ImpactNeutral impact

The discussions influence opinions on supplement usage and nutrition, but do not suggest a transformative shift in health practices or policies.

Abstract in brief

  • Vitamin C (ascorbic acid) is an essential nutrient for humans and some primates because they cannot produce it themselves, so it must be obtained through diet.
  • It acts as an electron donor and a cofactor for various enzymes, with its transport and levels in the body influenced by diet, absorption, and excretion, and understanding its physiological concentrations is key for research and clinical studies.
  • The article reviews current knowledge about vitamin C’s roles, highlights areas where understanding is limited, and suggests future research directions to better understand its functions and importance.]

Top posts

Most liked on X and Bluesky
L ❤ V E
@drkohilathas · X

Vitamin C functions as an electron donor in a variety of catalytic redox processes as an important cofactor of iron- and copper-dependent enzymes. https://t.co/XEymqxIMW6

Mar 17, 2023 · 29 likes · 7 shares · 48,095 followers View post →
金森重樹@ダイエットonlineサロン
@ShigekiKanamori · X

@orpelas 昨日読みました ビタミンCの箇所は間違いありそうです アスコルビン酸AAの輸送は ナトリウム依存性VCトランスポーター(SVCT1&2)で デヒドロアスコルビン酸DHAの輸送がGLUTだとおもうのですが 全部GLUTだと書いてましたね https://t.co/iWafygaHgP

Nov 7, 2021 · 16 likes · 1 share · 125,396 followers View post →
Catherine Collins
@RD_Catherine · X

A1: When it comes to nutritional options to boost immunity – focus on food. Supplements have a role, but they’re not always utilised like the nutrients from food. 30mg Vitamin C from an orange is likely to be 100% absorbed. https://t.co/MicoAoSTKx #RDUK #immunity

Nov 30, 2020 · 11 likes · 7,767 followers View post →
Catherine Collins
@RD_Catherine · X

A1: Bioavailability of vitamin C from supplements diminishes as dose increases. More isn’t better. That 1g #VitaminC supplement providing the equivalent of 4 litres of orange juice? Doesn’t pack a better immune punch https://t.co/MicoAoSTKx #RDUK #immunity

Nov 30, 2020 · 8 likes · 3 shares · 7,767 followers View post →
Catherine Collins
@RD_Catherine · X

A1: When it comes to vitamin supplements, more ≠ better. A low dose of 30mg Vitamin C is totally absorbed. But as dose increases, bioavailability reduces, with plasma levels remaining constant at 200-250mg/d. https://t.co/5mg3vRRAbd #RDUK #immunity https://t.co/LdmZe7xrPf

Nov 30, 2020 · 6 likes · 4 shares · 7,767 followers View post →
Medicinal Endobiome
@EndoMedChem · X

https://t.co/LSVpfmfKBc

Aug 23, 2024 · 3 likes · 947 followers View post →

All mentions

L ❤ V E
@drkohilathas · X

RT @drkohilathas: Vitamin C functions as an electron donor in a variety of catalytic redox processes as an important cofactor of iron- and…

Apr 19, 2025 · 7 shares · 48,095 followers View post →
Medicinal Endobiome
@EndoMedChem · X

https://t.co/LSVpfmfKBc

Aug 23, 2024 · 3 likes · 947 followers View post →
Flourish
@orimokor29 · X

RT @drkohilathas: Vitamin C functions as an electron donor in a variety of catalytic redox processes as an important cofactor of iron- and…

Sep 30, 2023 · 7 shares · 203 followers View post →
ZA
@LaikCumhuriyett · X

RT @drkohilathas: Vitamin C functions as an electron donor in a variety of catalytic redox processes as an important cofactor of iron- and…

Sep 29, 2023 · 7 shares · 7,097 followers View post →
Popeye ⚓
@Homecomputer19 · X

RT @drkohilathas: Vitamin C functions as an electron donor in a variety of catalytic redox processes as an important cofactor of iron- and…

Mar 17, 2023 · 7 shares · 1,622 followers View post →
Angel
@alineans3 · X

RT @drkohilathas: Vitamin C functions as an electron donor in a variety of catalytic redox processes as an important cofactor of iron- and…

Mar 17, 2023 · 7 shares · 29 followers View post →
L ❤ V E
@drkohilathas · X

Vitamin C functions as an electron donor in a variety of catalytic redox processes as an important cofactor of iron- and copper-dependent enzymes. https://t.co/XEymqxIMW6

Mar 17, 2023 · 29 likes · 7 shares · 48,095 followers View post →
金森重樹@ダイエットonlineサロン
@ShigekiKanamori · X

@orpelas 昨日読みました ビタミンCの箇所は間違いありそうです アスコルビン酸AAの輸送は ナトリウム依存性VCトランスポーター(SVCT1&2)で デヒドロアスコルビン酸DHAの輸送がGLUTだとおもうのですが 全部GLUTだと書いてましたね https://t.co/iWafygaHgP

Nov 7, 2021 · 16 likes · 1 share · 125,396 followers View post →
Fusion Prog Guy @ fusionprogguy.bsky.social
@FusionProgGuy · X

RT @RD_Catherine: A1: When it comes to vitamin supplements, more ≠ better. A low dose of 30mg Vitamin C is totally absorbed. But as dose in…

Dec 6, 2020 · 4 shares · 1,580 followers View post →
MSc Nutrition Glasgow
@MSc_Nutri_GLA · X

RT @RD_Catherine: A1: When it comes to vitamin supplements, more ≠ better. A low dose of 30mg Vitamin C is totally absorbed. But as dose in…

Dec 2, 2020 · 4 shares · 458 followers View post →
Pissed Off PT
@PissedOff_PT · X

RT @RD_Catherine: A1: When it comes to vitamin supplements, more ≠ better. A low dose of 30mg Vitamin C is totally absorbed. But as dose in…

Nov 30, 2020 · 4 shares · 1,254 followers View post →
Dr Frankie Phillips RD
@drfrankiep · X

RT @RD_Catherine: A1: When it comes to vitamin supplements, more ≠ better. A low dose of 30mg Vitamin C is totally absorbed. But as dose in…

Nov 30, 2020 · 4 shares · 1,671 followers View post →
Catherine Collins
@RD_Catherine · X

A1: When it comes to vitamin supplements, more ≠ better. A low dose of 30mg Vitamin C is totally absorbed. But as dose increases, bioavailability reduces, with plasma levels remaining constant at 200-250mg/d. https://t.co/5mg3vRRAbd #RDUK #immunity https://t.co/LdmZe7xrPf

Nov 30, 2020 · 6 likes · 4 shares · 7,767 followers View post →
Dr Frankie Phillips RD
@drfrankiep · X

RT @RD_Catherine: A1: Bioavailability of vitamin C from supplements diminishes as dose increases. More isn’t better. That 1g #VitaminC supp…

Nov 30, 2020 · 3 shares · 1,671 followers View post →
Caroline Bovey BEM
@CarolineBoveyRD · X

RT @RD_Catherine: A1: Bioavailability of vitamin C from supplements diminishes as dose increases. More isn’t better. That 1g #VitaminC supp…

Nov 30, 2020 · 3 shares · 4,853 followers View post →
Emma Carder
@EmmaCarderRD · X

RT @RD_Catherine: A1: Bioavailability of vitamin C from supplements diminishes as dose increases. More isn’t better. That 1g #VitaminC supp…

Nov 30, 2020 · 3 shares · 7,328 followers View post →
Catherine Collins
@RD_Catherine · X

A1: Bioavailability of vitamin C from supplements diminishes as dose increases. More isn’t better. That 1g #VitaminC supplement providing the equivalent of 4 litres of orange juice? Doesn’t pack a better immune punch https://t.co/MicoAoSTKx #RDUK #immunity

Nov 30, 2020 · 8 likes · 3 shares · 7,767 followers View post →
Catherine Collins
@RD_Catherine · X

A1: When it comes to nutritional options to boost immunity – focus on food. Supplements have a role, but they’re not always utilised like the nutrients from food. 30mg Vitamin C from an orange is likely to be 100% absorbed. https://t.co/MicoAoSTKx #RDUK #immunity

Nov 30, 2020 · 11 likes · 7,767 followers View post →
Kyle Victor Jose
@Smartteaser192 · X

@Jetlax @PhRheumaJr @endocrine_witch @S_erestepenem "Vitamin C bioavailability declines rapidly with dose. When 1250 mg of vitamin C is administered orally to healthy young men at steady state for that dose, bioavailability is 46%" (Padayatty & Levine, 2016). https://t.co/llbQTSpsxg

Mar 19, 2020 · 3 likes · 594 followers View post →