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Discussions highlight the innovative nature of replacing benzene with cubane, with posts mentioning the increased bioactivity in certain molecules and suggesting potential benefits for drug development. The tone reflects curiosity and optimism, emphasizing the scientific importance and possible applications of the findings.
Most discussions express support or interest in the research, recognizing its potential significance.
The topic of cubane as a benzene bioisostere sparks high interest due to its novelty and potential applications.
Participants reference specific aspects of the study, such as bioactivity results and implications for drug development, indicating moderate engagement.
While some see it as a promising scientific advancement, the perceived immediate impact remains moderate.
＠化学or薬学強い人 系統名か許容名教えてください 引用元:“Validating Eaton’s Hypothesis: Cubane as a Benzene Bioisostere” Williams, C. M. et al. Angew. Chem. Int. Ed. 2016，DOI: 10.1002/ange.201510675 https://t.co/y1BpdZpF1X
RT @HotPaperTweet: 【薬学】【有機合成化学】キュバンは医薬開発上有望なベンゼンの有望な生物学的等価体だと、類縁体合成による薬理活性の比較で確かめられた。映画、スター・ウォーズ／フォースの覚醒と同規模の注目と活躍が期待される。まさにキュバンの覚醒か。 https…
Cubanes are a unique class of molecules explored for their potential in medicinal chemistry. In this video, we discuss their use as a substitute for Benzene rings in new drug candidates and highlight various Cubane…
Cubane is a highly strained but stable hydrocarbon molecule gaining interest in medicinal chemistry because of its unique structure and low toxicity. This video discusses its synthesis, applications in drug development…
RT @HotPaperTweet: 【薬学】【有機合成化学】キュバンは医薬開発上有望なベンゼンの有望な生物学的等価体だと、類縁体合成による薬理活性の比較で確かめられた。映画、スター・ウォーズ／フォースの覚醒と同規模の注目と活躍が期待される。まさにキュバンの覚醒か。 https…
＠化学or薬学強い人 系統名か許容名教えてください 引用元:“Validating Eaton’s Hypothesis: Cubane as a Benzene Bioisostere” Williams, C. M. et al. Angew. Chem. Int. Ed. 2016，DOI: 10.1002/ange.201510675 https://t.co/y1BpdZpF1X
RT @HotPaperTweet: 【薬学】【有機合成化学】キュバンは医薬開発上有望なベンゼンの有望な生物学的等価体だと、類縁体合成による薬理活性の比較で確かめられた。映画、スター・ウォーズ／フォースの覚醒と同規模の注目と活躍が期待される。まさにキュバンの覚醒か。 https…
doi:10.1002/ange.201510675]. doi:10.1002/ANIE. R. S. McCredie, J. T. Pinhey, R. H. Prager, M. Rasmussen, E. Ritchie, 201510675 W. Taylor, Aust. J. Chem ...
2016, DOI: 10.1002/anie.201510675). MacMillan's team used the new methods to make cubane analogs of two drug molecules, including for a ...
Williams já demonstrou que os cubanos podem ser bioisósteros de benzeno eficazes (Angew. Chem., Int. Ed. 2016, DOI: 10.1002/anie.201510675). A ...
2016, DOI: 10.1002/anie.201510675)। मैक मिलन की टीम ने नए तरीकों का इस्तेमाल करके दो दवा ...
2016, DOI : 10.1002/anie.201510675). L'équipe de MacMillan a utilisé les nouvelles méthodes pour fabriquer des analogues de cubane de deux ...
Williams hat zuvor gezeigt, dass Cubane wirksame Benzol-Bioisostere sein können (Angew. Chem., Int. Ed. 2016, DOI: 10.1002/anie.201510675).
2016, DOI: 10.1002/anie.201510675). ทีมของ MacMillan ใช้เทคนิคใหม่ในการสร้าง cubane analogs ของโมเลกุลยา 2 ชนิด รวมถึงการรักษา cystic ...
2016, DOI: 10.1002/anie.201510675). MacMillan's team used the new methods to make cubane analogs of two drug molecules, including for a ...
... 10.1002/anie.201510675?casa_token=ID-ZpZBEetIAAAAA%3An1h83rheooNrodU_iR4jeqBDFSRFJG_P8wVw79EvxNYFv3DsfgaO2p5PUhpzz9oE6jyAwQha7zKHq24. If you ...
... 基溴，我猜你喜欢被烷基化. [已删除]. • 5年前 · https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201510675?casa_token=ID-ZpZBEetIAAAAA ...
... 10.1002/anie.201510675?casa_token=ID-ZpZBEetIAAAAA%3An1h83rheooNrodU_iR4jeqBDFSRFJG_P8wVw79EvxNYFv3DsfgaO2p5PUhpzz9oE6jyAwQha7zKHq24. Jos ...
... 10.1002/anie.201510675?casa_token=ID-ZpZBEetIAAAAA%3An1h83rheooNrodU_iR4jeqBDFSRFJG_P8wVw79EvxNYFv3DsfgaO2p5PUhpzz9oE6jyAwQha7zKHq24. Если ...
2016，DOI: 10.1002/ange.201510675. 関連リンク. Platonic Hydrocarbon (PDF, Baran's Group); Platonic Hydrocarbon – Wikipedia · 分子の多面体（有機 ...
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