PubHawk
April 2016 PMID 26908540

Key cost drivers of pharmaceutical clinical trials in the United States.

Aylin Sertkaya, Hui-Hsing Wong, Amber Jessup, Trinidad Beleche

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Mentions

46
Peak: 7 in Nov 2023
across 6 sources since Mar 2019

Extended reach

1,087,820
potential audience

Total likes

22,348

Video views

996,734

Mentions per month

Mar 2019 – Jun 2025

Where it's discussed

  • X / Twitter22 posts
  • News15 articles
  • Blogs4 articles
  • YouTube2 videos
  • Facebook2 posts
  • Bluesky1 posts

AI synopsis

What people are saying

The discussions reflect strong interest and engagement, with examples such as citing specific trial costs, mentioning research sources, and recommending videos to better understand the financial and scientific aspects. The tone combines curiosity and analytical reflection, highlighting how the article's focus on cost drivers informs broader conversations on drug development and healthcare costs.

AgreementModerate agreement

Most discussions acknowledge the significance of the article's insights into cost drivers and clinical trial expenses, indicating general agreement.

InterestHigh interest

Many participants show high interest by referencing specific cost figures, related videos, and the importance of understanding pharmaceutical research finances.

EngagementHigh engagement

Posts involve detailed references to research sources, videos, and conceptual discussions, demonstrating deep engagement with the topic.

ImpactModerate impact

While some posts suggest the information can influence decision-making or raise awareness, overall impact appears moderate due to the technical nature of the data.

Abstract in brief

  • The study highlights that the main factors influencing the high costs of pharmaceutical clinical trials in the US are clinical procedure expenses, administrative staff, and site monitoring costs, with costs varying significantly depending on the therapeutic area and trial phase.
  • Clinical trial costs increase notably with the phase, with Phase 1 costs starting around $1.4 million and rising to as much as nearly $5.3 million in Phase 3, depending on the therapeutic area.
  • Understanding these key cost drivers is essential because the rising costs can discourage drug companies from conducting trials, which may limit patient access to new treatments and impact public health.
Read the full abstract

Top posts

Most liked on X and Bluesky
Triall
@triallofficial · X

The average cost of a single phase 3 clinical trial is $19,9M

Jul 30, 2021 · 10 likes · 5 shares · 22,525 followers View post →
Nitya Sridhar
@nityasnotes · X

Inflation + depending on the specific case, these numbers can be even higher. Sources here: https://t.co/AgyZgH8xlX https://t.co/hvEt5UWZL4

Jan 3, 2025 · 9 likes · 5,852 followers View post →
Dr. Juliette
@FerryDanini · X

Philosophers of medicine, can you please react to this video https://t.co/Q1NoOx9Ik8

Nov 10, 2023 · 5 likes · 21,853 followers View post →
heyMAKWA
@heyMAKWA · X

a highly useful look on why so few high quality cosmetic clinical trials exist, and how you can critically examine related evidence to reach a conclusion even without them. https://t.co/kUKZ6PzlSm

Nov 20, 2023 · 5 likes · 1 share · 3,469 followers View post →
Caitlin Austin
@mizunocaitlin · X

@RaraSensei https://t.co/Myim6fbzZ6 I highly recommend watching this woman's video on the topic. It gives you a brief rundown on the chemical mechanism behind retinol skin care and the various forms you can get it in and the pros and cons of each. Only protip from me: you can't do it daily

Jan 10, 2024 · 4 likes · 1,939 followers View post →
Bruno Boni de Oliveira
@brunoboni · X

@gabrieln___ @hbredda @andregordon73 @jlbraga @fernandocluiz @cesaralpaiva @femisapien_z Se tiver curiosidade de mergulhar mais fundo nos custos e probs pharma: 1) custos: Key cost drivers of pharmaceutical clinical trials in the United States (Sertakya et al. 2016) 2) probabilidades: Clinical development success rates for investigational drugs (Hay et al. 2014)

Mar 5, 2019 · 2 likes · 8,051 followers View post →

All mentions

ⓘ we/her unity
@xmasiar · X

bahan #sebwapengingat https://t.co/IGyKRvl0zp

Jun 17, 2025 · 17 followers View post →
Nitya Sridhar
@nityasnotes · X

Inflation + depending on the specific case, these numbers can be even higher. Sources here: https://t.co/AgyZgH8xlX https://t.co/hvEt5UWZL4

Jan 3, 2025 · 9 likes · 5,852 followers View post →
exilade do navio
@Dragenye · X

@elmarkbgk @vlucasrocha Na verdade, cosméticos requerem menos estudos científicos para serem liberados. Isso quer dizer que não funcionam? Não necessariamente. Todos funcionam? Também não. Lab Muffin no Youtube tem um vídeo muito bom explicando sobre. https://t.co/TKWbtcBnyP

Oct 30, 2024 · 55 followers View post →
shark mami
@PapiCVMforme69 · X

https://t.co/VspSSlPLH0 คนไทยมานั่งเถียงกันเรื่องเรตินอลฟอร์มสกินแคร์ มาฟังจากคนรู้จริงๆแบบจิงๆดีกว่าค่า not หมอ not อินฟลู

Sep 30, 2024 · 134 followers View post →
neuto
@esoneuto · X

Bu ablanın konu üzerine vidyosu güzelmiş https://t.co/sZqwRQ75VJ

Mar 8, 2024 · 1 like · 315 followers View post →
Caitlin Austin
@mizunocaitlin · X

@RaraSensei https://t.co/Myim6fbzZ6 I highly recommend watching this woman's video on the topic. It gives you a brief rundown on the chemical mechanism behind retinol skin care and the various forms you can get it in and the pros and cons of each. Only protip from me: you can't do it daily

Jan 10, 2024 · 4 likes · 1,939 followers View post →
fée de la skincare
@HOELANl · X

y’a pleins de facteurs qui expliquent pourquoi les marques font pas + d’efforts (légaux, financiers, etc) de ce côté là labmuffin a fait une excellente vidéo dessus en partant de l’exemple de notre sacro-saint Rétinol : https://t.co/ZWnDWBjxkx

Jan 2, 2024 · 1 like · 14,253 followers View post →
heyMAKWA
@heyMAKWA · X

a highly useful look on why so few high quality cosmetic clinical trials exist, and how you can critically examine related evidence to reach a conclusion even without them. https://t.co/kUKZ6PzlSm

Nov 20, 2023 · 5 likes · 1 share · 3,469 followers View post →
✨
@FebriliaPramest · X

Niat dengerin ini biar cepet ngantuk, taunya menarik malah bikin mikir

Nov 17, 2023 · 354 followers View post →
Claudio Hidalgo
@chidalgo · X

muy interesante: Does retinol in skincare even work? https://t.co/7V48o3kGnb

Nov 15, 2023 · 1,591 followers View post →
Dr. Juliette
@FerryDanini · X

Philosophers of medicine, can you please react to this video https://t.co/Q1NoOx9Ik8

Nov 10, 2023 · 5 likes · 21,853 followers View post →
Dr Juliette
@ferrydanini.bsky.social · Bluesky

I think philosophers of medicine should watch and react to this video youtu.be/e6Z5Vr7uSiA?...

Nov 10, 2023 · 1 share View post →
Anandamide⚗️
@CyQuilp · X

If you have any interest in skin care, watch this. She's probably the best skinfluencer and an actual PhD cosmetic chemist. https://t.co/MRdIR1zKi8

Nov 6, 2023 · 1,853 followers View post →
Sue Sisley, MD
@suesisleymd · X

@kevinpayneLD21 @willhumble_az @utilityreporter @AZDHS @JenLongdon @TJShopeforAZ https://t.co/AaYvsVsMJ1 In a report submitted to the U.S. Department of Health and Human Services the AVERAGE cost of phase 1, 2, and 3 clinical trials is around $4, $13, and $20 million respectively. Some phase 3 trials were up to $59 million.

Jan 23, 2023 · 2,043 followers View post →
Mindaugas Galvosas, MD
@MGalvosas · X

These costs shared above were estimated in the analysis published by Dr. Aylin Sertkaya and colleagues in 2016. https://t.co/P1BRTSNc0w

Apr 1, 2022 · 1 like · 4,127 followers View post →
Nicholas Nolan
@NicholasNolan64 · X

@alyssamvance Check out https://t.co/T2vrr2F8sW and https://t.co/CwNNCyJU3d for the grinding minutiae (the infographic has a separate source). https://t.co/4ZCBlQCfHd

Nov 17, 2021 · 15 followers View post →
Carni
@carnivault · X

RT @triallofficial: The average cost of a single phase 3 clinical trial is $19,9M

Jul 30, 2021 · 5 shares · 149 followers View post →
KingNin84144407
@KingNin84144407 · X

RT @triallofficial: The average cost of a single phase 3 clinical trial is $19,9M

Jul 30, 2021 · 5 shares · 9 followers View post →
Triall
@triallofficial · X

The average cost of a single phase 3 clinical trial is $19,9M

Jul 30, 2021 · 10 likes · 5 shares · 22,525 followers View post →
off with the nazis heads
@fuckers2100 · X

@TomiHaataja @joonahermanni (Ja muut sen synteesin luvut eri vaiheille ilmeisesti tästä https://t.co/QkBdH7lGeU)

Jan 24, 2021 · 1 like · 716 followers View post →
William Hu
@williamhu43 · X

@ASlavitt https://t.co/qJIjAncEqA

Jul 3, 2020 · 1,622 followers View post →
moligotech
@moligotech · X

The heavy cost burden of #clinicalresearch can play a big role in the choice of #pharmaceutical companies to move forward with new drug innovations. Moligo Technologies has opened new possibilities through it's cost-effective way to #synthesize pure #DNA. https://t.co/rFd1AMwgDr https://t.co/ufrjy3GVHx

May 8, 2019 · 2 likes · 111 followers View post →
Bruno Boni de Oliveira
@brunoboni · X

@gabrieln___ @hbredda @andregordon73 @jlbraga @fernandocluiz @cesaralpaiva @femisapien_z Se tiver curiosidade de mergulhar mais fundo nos custos e probs pharma: 1) custos: Key cost drivers of pharmaceutical clinical trials in the United States (Sertakya et al. 2016) 2) probabilidades: Clinical development success rates for investigational drugs (Hay et al. 2014)

Mar 5, 2019 · 2 likes · 8,051 followers View post →