ITT解析の奥深さを学ぶのに最適な論文です。 https://t.co/lfPR7mfHGL
Randomized Trial of Introduction of Allergenic Foods in Breast-Fed Infants.
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Jan 2019 – Sep 2025Where it's discussed
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What people are saying
The discussions reflect a thoughtful engagement with the article, citing examples like the importance of early allergenic food introduction and referencing previous studies like LEAP and observational cohort data. Words like 'convincing,' 'real-world,' and references to specific figures and analyses reveal an interest in the study's depth, while careful tone indicates recognition of its potential impact without overstating it.
Many discussions acknowledge the findings and implications of the study, showing general support or recognition of its value.
The discussions indicate high curiosity about the research, with references to specific data points and related studies.
Participants refer to detailed aspects such as analysis types and observational data, demonstrating moderate engagement.
There is an understanding that the research might influence future guidelines, but the overall tone suggests cautious optimism rather than outright revolution.
Abstract in brief
- The study tested whether giving breastfed infants allergenic foods like peanuts, eggs, milk, sesame, fish, and wheat early in life can prevent food allergies, comparing early introduction to the typical practice of exclusive breastfeeding until 6 months.
- Results showed that while the initial intention-to-treat analysis did not prove early introduction effective, a per-protocol analysis (which considers only those who actually followed the plan) found a significantly lower rate of food allergies, especially peanut and egg allergies, in the early introduction group.
- The findings suggest that introducing certain allergenic foods early might help reduce the risk of developing some food allergies, but implementing this strategy is challenging and requires careful consideration of safety and adherence.
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Most liked on X and Bluesky自分がアレルギーマーチの権化ですからね。早期からピーナッツを摂取した方がアレルギーが減る可能性を示した論文を読んだ時はそういうことだったのか!と感動を覚えました(primary endpointは達成できていませんが)https://t.co/a8aPp1U26y 。
Interesting, seemingly convincing OBSERVATIONAL data from 3 cohorts. But is there hidden confounding as within a RCT (https://t.co/uqfc4rIieS) of early introduction of solids, duration of breast feeding in the intervention group was not reduced. #EAT https://t.co/ul6VQNJQaS
References: https://t.co/nT3f9m9oCY & https://t.co/hoyy3PaOhP https://t.co/22qN1aBc9y
Amrol: EAT trial added allergenic foods at 3mos of age https://t.co/9qeY5FeEAl #scaap23
It looks like not too early, but not delayed introduction of foodstuffs (= before approx. 6 months of age) may have some preventative effect, but again, more research is needed to work out the details. https://t.co/v1eTfiNa9b https://t.co/71WN9bf9KI
All mentions
Introducing Food Allergens to Babies: A Scientific Approach for Prevention
Welcome to part 2 of the allergen introduction series. This video discusses strategies for introducing the big 9 food allergens safely to infants, emphasizing early exposure to prevent food allergy development based on…
Preventing Food Allergies in Babies Using Scientific Strategies
This video covers science-based methods for introducing allergens to your baby, focusing on prevention of food allergies and early interventions to promote immune tolerance.
Введение аллергенов в прикорм #прикорм #самоприкорм #консультантпоприкорму
RT @SC_AAP: Amrol: EAT trial added allergenic foods at 3mos of age https://t.co/9qeY5FeEAl #scaap23
RT @SC_AAP: Amrol: EAT trial added allergenic foods at 3mos of age https://t.co/9qeY5FeEAl #scaap23
Amrol: EAT trial added allergenic foods at 3mos of age https://t.co/9qeY5FeEAl #scaap23
@adamsonjon @ian_wac @DrSeanMon Yep we had LEAP and then EAT Studies as well https://t.co/bRO9y7Eg7S https://t.co/p6XOxig2TL
In this study published in NEJM we can see a real world example of a drastic difference between ITT and PP analysis. Ultimately the ITT analysis is what was used to make the conclusion. https://t.co/VQxwDRLgri https://t.co/89xPFUbR3G
RT @syuichiao89: ITT解析の奥深さを学ぶのに最適な論文です。 https://t.co/lfPR7mfHGL
RT @syuichiao89: ITT解析の奥深さを学ぶのに最適な論文です。 https://t.co/lfPR7mfHGL
RT @syuichiao89: ITT解析の奥深さを学ぶのに最適な論文です。 https://t.co/lfPR7mfHGL
ITT解析の奥深さを学ぶのに最適な論文です。 https://t.co/lfPR7mfHGL
RT @ProfGRoberts: References: https://t.co/nT3f9m9oCY & https://t.co/hoyy3PaOhP
References: https://t.co/nT3f9m9oCY & https://t.co/hoyy3PaOhP https://t.co/22qN1aBc9y
RT @realscientists: It looks like not too early, but not delayed introduction of foodstuffs (= before approx. 6 months of age) may have som…
It looks like not too early, but not delayed introduction of foodstuffs (= before approx. 6 months of age) may have some preventative effect, but again, more research is needed to work out the details. https://t.co/v1eTfiNa9b https://t.co/71WN9bf9KI
自分がアレルギーマーチの権化ですからね。早期からピーナッツを摂取した方がアレルギーが減る可能性を示した論文を読んだ時はそういうことだったのか!と感動を覚えました(primary endpointは達成できていませんが)https://t.co/a8aPp1U26y 。
RT @janeway_tlr2: 伊藤隼也氏がRTした下記、原文 https://t.co/7rVDgQu7RV を読むと、「結果はアレルゲンの早期導入群と通常導入群との間で、食物アレルギーの発症率には、有意な差は認められませんでした」とある。 無知、無責任だろう! http…
@PeanutRD yes - See figure 3 B in the paper – that is where it shows 2 g of boiled egg per week is needed. https://t.co/hE3Qkb42Yl
RT @ProfGRoberts: Interesting, seemingly convincing OBSERVATIONAL data from 3 cohorts. But is there hidden confounding as within a RCT (htt…
RT @ProfGRoberts: Interesting, seemingly convincing OBSERVATIONAL data from 3 cohorts. But is there hidden confounding as within a RCT (htt…
Interesting, seemingly convincing OBSERVATIONAL data from 3 cohorts. But is there hidden confounding as within a RCT (https://t.co/uqfc4rIieS) of early introduction of solids, duration of breast feeding in the intervention group was not reduced. #EAT https://t.co/ul6VQNJQaS
@JacobGudiol @aliciapetra Det finns en annan interventionsstudie, där man undersökte hur tidig introduktion av 6 olika allergena födoämnen (jordnöt, tillagat ägg, komjölk, sesam, vit fisk och vete) påverkade födoämnesallergi, se https://t.co/x6rM02WsNg Här finns ännu ingen rapport om hur detta...
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