بعضی مقالات پزشکی قدیمی ادعا کردهاند مثلاً مصرف متعادل شراب با طول عمر بیشتر همبستگی دارد، ولی معلوم شده آن مقالات مشکل متدولوژی داشتهاند. این مقاله نشان داده با تصحیح متدولوژی، میشود دید که هرچه بیشتر الکل مصرف کنید عمرتان کوتاهتر میشود: https://t.co/2RmqsalQYL
Do "Moderate" Drinkers Have Reduced Mortality Risk? A Systematic Review and Meta-Analysis of Alcohol Consumption and All-Cause Mortality.
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Jan 2019 – Oct 2025Where it's discussed
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Several discussions emphasize the study's clarity on the lack of protective health benefits of low-volume drinking and the biases involved in previous analyses. For example, users referenced the 'abstainer bias' where former drinkers were incorrectly categorized, highlighting phrases like 'no net mortality benefit' and 'every dose harms,' which reflect a strong critical stance towards the perceived advantages of alcohol.
Most discussions express general agreement with the article's findings, questioning the supposed health benefits of low-volume alcohol consumption.
The topic has generated strong curiosity and engagement as people trace research methodologies and implications.
While some participants delve into details of other studies and biases, there are multiple discussions that reflect a lack of deep engagement overall.
Many contributors believe this publication will significantly influence public perception and discussions surrounding alcohol consumption and health.
Abstract in brief
- The study aimed to clarify the health benefits often associated with low-volume alcohol consumption by examining biases in previous research that categorized former and occasional drinkers as abstainers, which might distort mortality risk comparisons.
- A systematic review of studies involving nearly 4 million individuals found that while low-volume drinkers initially showed a reduced mortality risk, these benefits disappeared after accounting for biases and study quality characteristics.
- Ultimately, the research indicates that low-volume alcohol consumption does not significantly lower mortality risk when better study design and adjustments are applied, challenging the previously held view of a protective health effect.
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Most liked on X and BlueskyBuat yg mungkin awam, meta-analysis salah satu tipe studi yg paling susah & paling insightful. Dia bukan kumpulin data sendiri, tapi menganalisis puluhan/ratusan studi lain demi liat pola besar. Contoh meta-analysis soal alkohol: https://t.co/DznrT1EXid https://t.co/ogxCmZkhF4
"Meta-analyses adjusting for these factors find that low-volume alcohol consumption has no net mortality benefit compared with lifetime abstention or occasional drinking." El alcohol solo es beneficioso para la salud de quien lo vende. https://t.co/01yMVeodKV
Of the reviews that excluded former drinkers from the reference group, only one review (@UVic_CISUR, 2016) was considered at low risk of bias, and found that risk of death increases with increasing alcohol intake, with no evidence of protective effects: https://t.co/3lilo8WmMN
@foundmyfitness @BStulberg ”However, low-volume drinkers may appear healthy only because the "abstainers" with whom they are compared are biased toward ill health.” https://t.co/VWz9XzsTN7 Some researchers argue that among ‘abstainers’ there are many who have had serious alcohol addiction in the past.
En 2016, quand Tim Stockwell @UVic_CISUR avait publié son article sur la courbe en J, il avait été contacté par les viticulteurs français
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@ded_ruckus type 2 diabetics. https://t.co/5OyAp3qZiU This paper, which was a meta-analysis that attempted to correct for study design and patient variables found that - at best - low drinkers had no worse mortality risk than abstainers. https://t.co/hPjJsSrbm8
@Granville1977 @BrunoTertrais @le_Parisien Puis 2016 https://t.co/CHDxUiPBrp
RT @PeteSarich: Of the reviews that excluded former drinkers from the reference group, only one review (@UVic_CISUR, 2016) was considered a…
RT @roozbehp: بعضی مقالات پزشکی قدیمی ادعا کردهاند مثلاً مصرف متعادل شراب با طول عمر بیشتر همبستگی دارد، ولی معلوم شده آن مقالات مشکل متدو…
RT @roozbehp: بعضی مقالات پزشکی قدیمی ادعا کردهاند مثلاً مصرف متعادل شراب با طول عمر بیشتر همبستگی دارد، ولی معلوم شده آن مقالات مشکل متدو…
RT @roozbehp: بعضی مقالات پزشکی قدیمی ادعا کردهاند مثلاً مصرف متعادل شراب با طول عمر بیشتر همبستگی دارد، ولی معلوم شده آن مقالات مشکل متدو…
بعضی مقالات پزشکی قدیمی ادعا کردهاند مثلاً مصرف متعادل شراب با طول عمر بیشتر همبستگی دارد، ولی معلوم شده آن مقالات مشکل متدولوژی داشتهاند. این مقاله نشان داده با تصحیح متدولوژی، میشود دید که هرچه بیشتر الکل مصرف کنید عمرتان کوتاهتر میشود: https://t.co/2RmqsalQYL
@Kubalongozny @PolskiKociarz @pawilon21 Proszę uprzejmie, dwa przeglądy i metaanalizy 694 baz i 87 badań, które łącznie pokazują, że każda dawka alkoholu szkodzi, wraz z wyjaśnieniem, jak zły dobór prób w ogóle doprowadził do wyników z dobrymi skutkami alkoholu https://t.co/uiOWRoNpOG https://t.co/q6mWuwU0Tg
@GeRoQu77 @Chm1elka @wojcis @Bartolomeoz37 @pawilon21 Ta hipoteza padła. Analiza ryzyka wskazuje, że alkohol zawsze czyni znacznie więcej szkód niż pożytku https://t.co/uiOWRoNpOG Dobre skutki wychodziły dlatego, że w badaniach za abstynentów brano ludzi, którzy z przyczyn zdrowotnych nie mogli pić https://t.co/q6mWuwU0Tg
@foundmyfitness @BStulberg ”However, low-volume drinkers may appear healthy only because the "abstainers" with whom they are compared are biased toward ill health.” https://t.co/VWz9XzsTN7 Some researchers argue that among ‘abstainers’ there are many who have had serious alcohol addiction in the past.
@CoralieBorel @SaiyanBio Celle-là ? C'est justement d'elle qu'on parle. https://t.co/YaOsXGfoJE
@GuigoDalphinus @SaiyanBio https://t.co/S7zYDEHjRv https://t.co/KmmrROR4ST? https://t.co/lfnLzxrl85 https://t.co/VAGVXJcOb7 https://t.co/8jIi30tksU
@JuhanaHarju @HenriAlen Tässä on yksi esimerkki siitä, kuinka kompleksinen asia on. Stockwell et al. J Stud Alcohol Drugs 2016 Mar;77(2):185-98. doi: 10.15288/jsad.2016.77.185.
Of the reviews that excluded former drinkers from the reference group, only one review (@UVic_CISUR, 2016) was considered at low risk of bias, and found that risk of death increases with increasing alcohol intake, with no evidence of protective effects: https://t.co/3lilo8WmMN
飲酒にメリットは無いよ〜 https://t.co/kihUfkUsHR
@OssAlcol @SubstackInc Come perchè ? Perchè è un bias, una distorsione agevolmente modificabile se si controlla per le variabili che NON sono prese adeguatamente in considerazione. Lo dicono le metanalisi , non risulta? Chissà perchè … https://t.co/DWbun8ooyF https://t.co/KYcHRAyRDk
Source: https://t.co/mpxiTtNaz2
This article is an update of a very large systematic review published in 2016: https://t.co/3lilo8WmMN
@ProfMBassetti Con grande stima
@emanuelecat @GerardoDAmico @LaStampa @AntonellaViolaX @ChiediLeProve https://t.co/5Z4GGgfczI https://t.co/O7EwKOPiZ1
@ramella_f qui un'altra sulla mortalità generale: no significant reduction in mortality risk https://t.co/uDqXeTLDUr fra l'altro anche nel suo articolo sottolineano problemi come abstainer bias, rischio di oltrepassare le basse dosi, cancri non mortali anche per chi pare guadagnare 1 anno +
@drquinngyn @TraumaSoapBoxes @Rummy26 https://t.co/fZd9bbFZk4
@GeekNfit Parmis les 3 meta plus citées sur scholar, deux concluent à une courbe en J même avec ajustement, l'autre à un seuil à partir duquel il y a un effet nocif; aucune des trois à un effet nocif à petite dose. https://t.co/zlRr8PdgsD https://t.co/SoSgQq9wSZ https://t.co/stW466TizA
@jessbreathes @hubermanlab https://t.co/Ul9bjB9o4B
@mike_lustgarten @AhmedMa43780221 Sorry, here is the active link: https://t.co/K8W4VTURnO
@mike_lustgarten @AhmedMa43780221 Here is one fairly definitive one: Stockwell T, Zhao J, Panwar S, Roemer A, Naimi T, Chikritzhs T. Do "moderate" drinkers have reduced mortality risk? A systematic review and meta-analysis of alcohol consumption and all-cause mortality. J Stud Alcohol Drugs. 2016;77(2):185-198.
With the new study about alcohol’s health benefits making the news, remember: when accounting for abstainer bias (former drinkers included in multiple academic studies as absolute abstainers), there is no health benefit derived from drinking a carcinogen. https://t.co/HXBM47Na9j
@ffenp0cken @Don_Promillo_ @M_f_G_Pit @ARD_BaB Was ein Schwachsinn. Hier mal ein paar Studien die belegen das auch geringer Alkoholkonsum nicht gesund ist: https://t.co/2368xRs7t0 - https://t.co/GaFgdMNE0P - https://t.co/oC20M9ErNQ
@DPeich @RadiactivoMan @julia_otero No es "mi" ciencia. Afortunadamente, la ciencia no soy yo, ni tú, sino que la hacen los investigadores de forma independiente, como en estos artículos de aquí: DOI: 10.15288/jsad.2016.77.185 DOI: 10.1016/S0140-6736(18)30134-X ¿Algún paper que diga lo contrario? https://t.co/aiUcz8Ocva
However, a SR & meta regression analysis (Stockwell et al 2016) of studies investigating alcohol use and mortality risk after controlling for quality-related study characteristics was conducted in a population of 3,998,626 individuals https://t.co/SJLsBVpMCe
@ACNewman You might want to read this study, or at least the abstract: https://t.co/Ni5j1uvWPZ
@DuraMauricia @osbserver @nikamonina @anvaltej Ni yo ni estos: https://t.co/saAIkBXymh Si lees el estudio, de la misma fecha que el tuyo (2016) que es un metaanálisis, verás que el consumo moderado (<25g/día) no tiene efectos ni positivos ni negativos. Ciertas personas tienen genéticamente problemas para metabolizar (+)
@jamiegoode @areniglobal @ProfDavidNutt The J-curve can be explained as an artifact or a misforced interpretation. Read this meta analysis: https://t.co/2K1T0XqUON. I am into the wine, but we need to discuss without prejudices
@satyalumesh I think this is misleading. I don’t think there is any evidence for “रक्सी थोरै खाए औषधि हुन्छ।” Original study: https://t.co/JJCJ37Hg56
@jerryteixeira @ScepticalDoctor "Our findings provide further strong evidence for the involvement of the alcohol dehydrogenase 1B gene (ADH1B) gene in the pathogenesis of alcohol dependence and abuse..." https://t.co/ETuiFwztNS Mendelian randomization study from previous comment: https://t.co/iq1AJLQoM2
@cjsnowdon @AndyTowersNZ It isn't such an outlier, just a very good example. For example, there's several systematic reviews that found that the relationship is largely or totally attenuated when controlling for confounding factors https://t.co/bn1J4o8ek2
RT @PabloRichly: "Meta-analyses adjusting for these factors find that low-volume alcohol consumption has no net mortality benefit compared…
RT @PabloRichly: "Meta-analyses adjusting for these factors find that low-volume alcohol consumption has no net mortality benefit compared…
"Meta-analyses adjusting for these factors find that low-volume alcohol consumption has no net mortality benefit compared with lifetime abstention or occasional drinking." El alcohol solo es beneficioso para la salud de quien lo vende. https://t.co/01yMVeodKV
@DirkNetter @Filtermag_org @speele5 A decent summary of the evidence on alcohol use and longevity with important questions. Unfortunately, the author seem to have overlooked some important papers on this matter, including this one: https://t.co/U1CmmLdnLT https://t.co/5SZZQkHiC6
@glenhartman11 @keccers It's generally best to avoid pop culture sites when it comes to booze related science. "After adjustment for abstainer biases and quality-related study characteristics, no significant reduction in mortality risk was observed for low-volume drinkers“ https://t.co/qhFhWeMvHd
完全に消え 酒をまったく飲まない 飲んでも週に1杯以下 という人が最も長生きするみたい 1日2〜3杯までなら健康リスクはないって結論のよう https://t.co/p6VaEYo8fI #自分用メモ
RT @addict38: En 2016, quand Tim Stockwell @UVic_CISUR avait publié son article sur la courbe en J, il avait été contacté par les viticulte…
RT @addict38: En 2016, quand Tim Stockwell @UVic_CISUR avait publié son article sur la courbe en J, il avait été contacté par les viticulte…
En 2016, quand Tim Stockwell @UVic_CISUR avait publié son article sur la courbe en J, il avait été contacté par les viticulteurs français
RT @nathanaeldotid: Buat yg mungkin awam, meta-analysis salah satu tipe studi yg paling susah & paling insightful. Dia bukan kumpulin data…
RT @nathanaeldotid: Buat yg mungkin awam, meta-analysis salah satu tipe studi yg paling susah & paling insightful. Dia bukan kumpulin data…
RT @nathanaeldotid: Buat yg mungkin awam, meta-analysis salah satu tipe studi yg paling susah & paling insightful. Dia bukan kumpulin data…
RT @nathanaeldotid: Buat yg mungkin awam, meta-analysis salah satu tipe studi yg paling susah & paling insightful. Dia bukan kumpulin data…
RT @nathanaeldotid: Buat yg mungkin awam, meta-analysis salah satu tipe studi yg paling susah & paling insightful. Dia bukan kumpulin data…
RT @nathanaeldotid: Buat yg mungkin awam, meta-analysis salah satu tipe studi yg paling susah & paling insightful. Dia bukan kumpulin data…
RT @nathanaeldotid: Buat yg mungkin awam, meta-analysis salah satu tipe studi yg paling susah & paling insightful. Dia bukan kumpulin data…
RT @nathanaeldotid: Buat yg mungkin awam, meta-analysis salah satu tipe studi yg paling susah & paling insightful. Dia bukan kumpulin data…
RT @nathanaeldotid: Buat yg mungkin awam, meta-analysis salah satu tipe studi yg paling susah & paling insightful. Dia bukan kumpulin data…
RT @nathanaeldotid: Buat yg mungkin awam, meta-analysis salah satu tipe studi yg paling susah & paling insightful. Dia bukan kumpulin data…
RT @nathanaeldotid: Buat yg mungkin awam, meta-analysis salah satu tipe studi yg paling susah & paling insightful. Dia bukan kumpulin data…
Buat yg mungkin awam, meta-analysis salah satu tipe studi yg paling susah & paling insightful. Dia bukan kumpulin data sendiri, tapi menganalisis puluhan/ratusan studi lain demi liat pola besar. Contoh meta-analysis soal alkohol: https://t.co/DznrT1EXid https://t.co/ogxCmZkhF4
High analysis non_free study found there is no low mortality related to low volume alcohol drinker #humanos #AlcoholBan #addiction https://t.co/Ra42Y3uG1p
@Kaorin_n0613 https://t.co/8GVYv3NGhk ちょっとでも飲んだら悪影響だそうです。いや、今でも飲みたいですよ
@brianmackinney https://t.co/Zz0ne13H9a
@MuffinScript @fishinatree @RoqueMatuslll @lexfridman You describe a case-control study. But there is no way you would get the ethic commission to agree to such a study over many years. Usually, these studies are done as a longitudinal study that asks the test persons how much they drink. Example: https://t.co/ej7CQZYaF1
Peccato che non sia l’unica dimostrazione ma vi siano metanalisi che dimostrano che i riportati effetti positivi del bere moderato siano assolutamente “imperfetti”, fallaci,errati. In effetti non potrà mai tornare che un tossico e cancerogeno possa giovare.https://t.co/7yLg12csKX https://t.co/u6hgE4Bp4U
@OssAlcol Peccato che non sia l’unica dimostrazione ma vi siano metanalisi che dimostrano che i riportati effetti positivi del bere moderato siano assolutamente “imperfetti”, fallaci,errati. In effetti non potrà mai tornare che un tossico e cancerogeno possa giovare.https://t.co/KwNBF7k5aP
@TreDiMediolanum @joerogan @arieljones411 @UCRiverside @EurekAlert @TIME "Moderate Drinking Has No Health Benefits, Large Review of Studies Concludes"https://t.co/DSJ4bW6aPp Stockwell T et al "Do 'Moderate' Drinkers Have Reduced Mortality Risk? A Systematic Review and Meta-Analysis of Alcohol Consumption and All-Cause Mortality"https://t.co/KMinDhOAUZ
@JaneStanley64 @MichaelNey19 @JSG_54 @wilsanborn777 @Angelsgal02 @soofriends @Deeenst @CTSuboxone @LadyAg72 @SueBreen6 @StopBadDocs @MrPetesonality @Dsntslp @eullrich11 @Irishbrat1966 @CContrarus @jlrmackay @Jdserrano1976 @HeatherLinda11 @Faithgirlee @process_x @Bozo21inc @LizYoun58386941 @AMERICANTRUMP2 @LelenaPeacock @minxy99 @DawsonInga @Rosesdaughter61 @JudyOsburn8 @dirtydawgjp @ramseypeacock @Talkeetna101 @Txsconstitution @urbanfatbiker @painadvocateAR @keesaroo @DanitaJMD @mlvanbrit @DiaryGods @SparlingAngela @pechilvr @NitaGhei @RollinsLynda @dashdashdotdas1 @KGTheAscent @donnelsonguy @jmkillingnyc @puppyluvr312 @RogueWolf2001 @BostonBubbalooo Alcohol companies actually fund most of these studies. https://t.co/ebmXv0l5ea https://t.co/41hoc2NlIY
今まで適量の酒は体に良いと言われていましたが、これからは「百害あって一理なし」が新常識であるといえます。 【ソース】 https://t.co/ZhtBJ70hN3
Do “Moderate” Drinkers Have Reduced Mortality Risk? A Systematic Review and Meta-Analysis of Alcohol Consumption and All-Cause Mortality: Journal of Studies on Alcohol and Drugs: Vol 77, No 2 https://t.co/A1gmKOpG4o
RT @hataboSAN: Do "Moderate" Drinkers Have Reduced Mortality Risk? A Systematic Review and Meta-Analysis of Alcohol Consumption and All-Cau…
RT @hataboSAN: Do "Moderate" Drinkers Have Reduced Mortality Risk? A Systematic Review and Meta-Analysis of Alcohol Consumption and All-Cau…
Do "Moderate" Drinkers Have Reduced Mortality Risk? A Systematic Review and Meta-Analysis of Alcohol Consumption and All-Cause Mortality. https://t.co/wxGy7NQjxV
@Pourquoidocteur Quand Tim Stockwell (https://t.co/TReUD1NH9s) avait publié sa méta-analyse en 2016 https://t.co/Nfjq0moGKF, il avait été rapidement contacté par le lobby viticole français contestant l'absence d'effet bénéfique des faibles doses....
@kouki53531 研究では1日あたり純アルコール量1.3〜24.9gまでであれば毎日飲んでも、死亡危険率は上がらないという論文があります! 判断材料にしてみて下さい☺️ ちなみ、24.9gは 40度のお酒だと約79mlです! 英語論文なんですけど一応貼っておきます! https://t.co/Odtey994Ad