1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have some truth. What we see here is cellular damage caused as a “DIRECT EFFECT” of using a cell toxin - Statin to Artificially lower cholesterol.
Statin-Associated Side Effects.
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Jul 2022 – Aug 2025Where it's discussed
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X / Twitter114 posts
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AI synopsis
What people are saying
Discussions often highlight specific concerns, such as the mention of women being underrepresented in clinical trials and how this affects their risk estimates. One poster notes statins as 'brain poisons' leading to severe neurological side effects, while another emphasizes that up to 90% of reported side effects may be due to the nocebo effect. These choices of words showcase strong emotions about the topic and indicate a belief that the risks of statins may be underestimated.
Many discussions express concerns about the side effects associated with statin use, indicating a general consensus on their potential negative impacts.
The variety of topics and specific issues raised in the discussions reflect a high level of interest in the implications of statin use and associated side effects.
Posters engage at different depths, with some sharing personal anecdotes while others refer to specific studies, suggesting moderate engagement overall.
A significant number of users assert that statin-associated side effects can deter patients from adhering to their medication regimes, demonstrating a belief in their considerable impact on health outcomes.
Abstract in brief
- Statins, also known as HMG-CoA reductase inhibitors, are generally well tolerated but can cause various side effects, collectively known as statin-associated symptoms (SAS), which include muscle pain, diabetes, and neurological issues.
- Statin-associated muscle symptoms (SAMS) are the most common, affecting 5-10% of users, while more severe muscle conditions like rhabdomyolysis and statin-induced necrotizing autoimmune myopathy (SINAM) are much rarer.
- While there's strong evidence linking statins to diabetes, the connection to other SAS is mainly based on anecdotal reports, and managing these symptoms often involves adjusting the treatment or switching to alternative medications.
Top posts
Most liked on X and BlueskyBempedoic Acid in Secondary Prevention, Is It Effective? Bempedoic acid is an oral adenosine triphosphate citrate lyase inhibitor that was shown to reduce the risk of major adverse cardiovascular events in patients unable to take statins due to statin-associated side effects who https://t.co/yhiorkTtLU
Women More Likely To Have 1️⃣ Under-representation in Lipid and CV clinical trials 2️⃣ CV risk under-estimated 3️⃣ Delays in initiation of statin therapy 4️⃣ More statin associated side effects 5️⃣ Fluctuations in lipid levels due to hormonal changes 6️⃣ Lower achievement of https://t.co/ijLhGPWqbL
@CartlandDavid These drugs are another brain poisons... CNS adverse effects are real My relative died of Parkinson's due to Statins .. @CartlandDavid https://t.co/DzkND0TU4e https://t.co/SaKiGk0FIY
6/7 Statin users. Particularly those receiving Atorvastatin, with a similar clinical, biochemical, and histological pattern as non–drug- induced autoimmune hepatitis. One of THE main Statin-associated side effects is drug induced liver injury.
Most frequent reasons for non-use were statin associated side effects (41%) and general intolerance (20%) ⭐️NLP extraction of data improved identification of reasons for pts not being on high intensity statins
All mentions
Understanding Statin Side Effects and Mitochondrial Mechanisms
Statin adverse effects mostly involve muscle problems, linked to mitochondrial dysfunction. Higher doses, drug interactions, and genetic factors increase risks. Awareness of nonmuscle side effects is low, emphasizing…
Atorvastatin Side Effects: Key Risks and Research Findings
Millions take atorvastatin daily, but are you aware of the 15 documented side effects that can impact your health? This video covers concerns like muscle pain, liver enzyme elevations, and a higher risk of diabetes…
Understanding Statin-Associated Muscle Symptoms and Their Mechanisms
Muscle pain is a common side effect of statins. This video explains the science behind statin-associated muscle symptoms (SAMS), discussing how statins may disrupt CoQ10 production and mitochondrial function, and their…
Understanding Statins: Benefits and Side Effects Explained
This video discusses statins, medications commonly used to control cholesterol levels. We explore their benefits, the side effects known as statin-associated symptoms, and how to manage them effectively.
eg. what ChatGPT says about the test results and the symptoms you mentioned
#DYK? A small number of patients experience #statin-associated side effects such as:
RT @MohammedAlo: Women More Likely To Have 1️⃣ Under-representation in Lipid and CV clinical trials 2️⃣ CV risk under-estimated 3️⃣ Delays…
@DuaneBiggs Complications: https://t.co/GwF94LvQ2M , https://t.co/Qfierx7CbV , They also cause Diabetes, Autoimmune diseases, and lots of Neuromuscular issues!
RT @MohammedAlo: Women More Likely To Have 1️⃣ Under-representation in Lipid and CV clinical trials 2️⃣ CV risk under-estimated 3️⃣ Delays…
RT @MohammedAlo: Women More Likely To Have 1️⃣ Under-representation in Lipid and CV clinical trials 2️⃣ CV risk under-estimated 3️⃣ Delays…
RT @MohammedAlo: Women More Likely To Have 1️⃣ Under-representation in Lipid and CV clinical trials 2️⃣ CV risk under-estimated 3️⃣ Delays…
RT @MohammedAlo: Women More Likely To Have 1️⃣ Under-representation in Lipid and CV clinical trials 2️⃣ CV risk under-estimated 3️⃣ Delays…
RT @MohammedAlo: Women More Likely To Have 1️⃣ Under-representation in Lipid and CV clinical trials 2️⃣ CV risk under-estimated 3️⃣ Delays…
RT @MohammedAlo: Women More Likely To Have 1️⃣ Under-representation in Lipid and CV clinical trials 2️⃣ CV risk under-estimated 3️⃣ Delays…
RT @MohammedAlo: Women More Likely To Have 1️⃣ Under-representation in Lipid and CV clinical trials 2️⃣ CV risk under-estimated 3️⃣ Delays…
RT @MohammedAlo: Women More Likely To Have 1️⃣ Under-representation in Lipid and CV clinical trials 2️⃣ CV risk under-estimated 3️⃣ Delays…
RT @MohammedAlo: Women More Likely To Have 1️⃣ Under-representation in Lipid and CV clinical trials 2️⃣ CV risk under-estimated 3️⃣ Delays…
RT @MohammedAlo: Women More Likely To Have 1️⃣ Under-representation in Lipid and CV clinical trials 2️⃣ CV risk under-estimated 3️⃣ Delays…
RT @MohammedAlo: Women More Likely To Have 1️⃣ Under-representation in Lipid and CV clinical trials 2️⃣ CV risk under-estimated 3️⃣ Delays…
RT @MohammedAlo: Women More Likely To Have 1️⃣ Under-representation in Lipid and CV clinical trials 2️⃣ CV risk under-estimated 3️⃣ Delays…
RT @MohammedAlo: Women More Likely To Have 1️⃣ Under-representation in Lipid and CV clinical trials 2️⃣ CV risk under-estimated 3️⃣ Delays…
RT @MohammedAlo: Women More Likely To Have 1️⃣ Under-representation in Lipid and CV clinical trials 2️⃣ CV risk under-estimated 3️⃣ Delays…
RT @MohammedAlo: Women More Likely To Have 1️⃣ Under-representation in Lipid and CV clinical trials 2️⃣ CV risk under-estimated 3️⃣ Delays…
Women More Likely To Have 1️⃣ Under-representation in Lipid and CV clinical trials 2️⃣ CV risk under-estimated 3️⃣ Delays in initiation of statin therapy 4️⃣ More statin associated side effects 5️⃣ Fluctuations in lipid levels due to hormonal changes 6️⃣ Lower achievement of https://t.co/ijLhGPWqbL
statin関連副作用 https://t.co/9lwxaHVUjX SAMS(statin関連筋症状):筋肉痛,横紋筋融解症,statin誘発壊死性自己免疫性myopathy https://t.co/3dXx1uZMjG cho⬆️→糖尿risk⬇️ 中枢神経影響:認知機能⬇️ 腎機能⬇️ 腱断裂 https://t.co/7eVrd43fh3 cho⬇️→出血性脳卒中⬆️ 虚血性脳卒中既往で出血性脳卒中⬆️
Clarithromycin has an interaction with atorvastatin leading to an increased risk of statin-associated side effects.
RT @Marion436842126: 6/7 Statin users. Particularly those receiving Atorvastatin, with a similar clinical, biochemical, and histological…
6/7 Statin users. Particularly those receiving Atorvastatin, with a similar clinical, biochemical, and histological pattern as non–drug- induced autoimmune hepatitis. One of THE main Statin-associated side effects is drug induced liver injury.
RT @GastricpH: @CartlandDavid These drugs are another brain poisons... CNS adverse effects are real My relative died of Parkinson's due to…
RT @GastricpH: @CartlandDavid These drugs are another brain poisons... CNS adverse effects are real My relative died of Parkinson's due to…
RT @GastricpH: @CartlandDavid These drugs are another brain poisons... CNS adverse effects are real My relative died of Parkinson's due to…
RT @GastricpH: @CartlandDavid These drugs are another brain poisons... CNS adverse effects are real My relative died of Parkinson's due to…
RT @GastricpH: @CartlandDavid These drugs are another brain poisons... CNS adverse effects are real My relative died of Parkinson's due to…
RT @GastricpH: @CartlandDavid These drugs are another brain poisons... CNS adverse effects are real My relative died of Parkinson's due to…
RT @GastricpH: @CartlandDavid These drugs are another brain poisons... CNS adverse effects are real My relative died of Parkinson's due to…
@CartlandDavid These drugs are another brain poisons... CNS adverse effects are real My relative died of Parkinson's due to Statins .. @CartlandDavid https://t.co/DzkND0TU4e https://t.co/SaKiGk0FIY
RT @MohammedAlo: Bempedoic Acid in Secondary Prevention, Is It Effective? Bempedoic acid is an oral adenosine triphosphate citrate lyase i…
RT @MohammedAlo: Bempedoic Acid in Secondary Prevention, Is It Effective? Bempedoic acid is an oral adenosine triphosphate citrate lyase i…
RT @MohammedAlo: Bempedoic Acid in Secondary Prevention, Is It Effective? Bempedoic acid is an oral adenosine triphosphate citrate lyase i…
RT @MohammedAlo: Bempedoic Acid in Secondary Prevention, Is It Effective? Bempedoic acid is an oral adenosine triphosphate citrate lyase i…
RT @MohammedAlo: Bempedoic Acid in Secondary Prevention, Is It Effective? Bempedoic acid is an oral adenosine triphosphate citrate lyase i…
RT @MohammedAlo: Bempedoic Acid in Secondary Prevention, Is It Effective? Bempedoic acid is an oral adenosine triphosphate citrate lyase i…
RT @MohammedAlo: Bempedoic Acid in Secondary Prevention, Is It Effective? Bempedoic acid is an oral adenosine triphosphate citrate lyase i…
RT @MohammedAlo: Bempedoic Acid in Secondary Prevention, Is It Effective? Bempedoic acid is an oral adenosine triphosphate citrate lyase i…
Bempedoic Acid in Secondary Prevention, Is It Effective? Bempedoic acid is an oral adenosine triphosphate citrate lyase inhibitor that was shown to reduce the risk of major adverse cardiovascular events in patients unable to take statins due to statin-associated side effects who https://t.co/yhiorkTtLU
@shashiiyengar @jasongordo626 @arunkumar3112 @jasmeet481 https://t.co/DzkND0TmeG Reference : statin induced diabetes mellitus https://t.co/1PEyYHMsGy
@pcny_nyc @PierreKory @MidwesternDoc https://t.co/DzkND0TmeG Atleast we need to agree with the fact Statins cause diabetes mellitus & have CNS side effects...
RT @GastricpH: https://t.co/52wqxZ0MU7 @TheDrMAWZ @MaxGulhaneMD https://t.co/IbhKlRQ57c
https://t.co/52wqxZ0MU7 @TheDrMAWZ @MaxGulhaneMD https://t.co/IbhKlRQ57c
RT @atherosociety: DYK? Patients can experience statin-associated side effects, which can lead to medication non-adherence and result in ad…
RT @MutazAlsabah: Statin associated side effects . IAS Regional Federation ( MENA and Africa ).
RT @atherosociety: DYK? Patients can experience statin-associated side effects, which can lead to medication non-adherence and result in ad…
Statin associated side effects . IAS Regional Federation ( MENA and Africa ). https://t.co/56iShtEZlt
RT @atherosociety: DYK? Patients can experience statin-associated side effects, which can lead to medication non-adherence and result in ad…
DYK? Patients can experience statin-associated side effects, which can lead to medication non-adherence and result in adverse health outcomes. Learn more about factors that can affect patients' use of statins in IAS' infographic ▶️ https://t.co/tCyIFWXjDJ https://t.co/r670iSasqY
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
RT @holmanm: 1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have som…
1/2 These aren’t pesky little Statin associated “Side Effects” Let’s call them what they REALLY ARE shall we ? Let’s have some truth. What we see here is cellular damage caused as a “DIRECT EFFECT” of using a cell toxin - Statin to Artificially lower cholesterol.
@holmanm in this article, however, it is uncertain whether statins have a negative effect on the cns. there are probably studies that show that dementia develops as well as studies that see a protective effect of statins. https://t.co/LVFGi8kDaE
RT @Gurleen_Kaur96: Most frequent reasons for non-use were statin associated side effects (41%) and general intolerance (20%) ⭐️NLP extrac…
RT @Gurleen_Kaur96: Most frequent reasons for non-use were statin associated side effects (41%) and general intolerance (20%) ⭐️NLP extrac…
RT @Gurleen_Kaur96: Most frequent reasons for non-use were statin associated side effects (41%) and general intolerance (20%) ⭐️NLP extrac…
RT @Gurleen_Kaur96: Most frequent reasons for non-use were statin associated side effects (41%) and general intolerance (20%) ⭐️NLP extrac…
Most frequent reasons for non-use were statin associated side effects (41%) and general intolerance (20%) ⭐️NLP extraction of data improved identification of reasons for pts not being on high intensity statins
@MDinCanada @holmanm A milk toast paper. First, do no harm https://t.co/JhnCrhehC6
13. PCDS Statin: Patients w/ ASCVD were significantly more likely to be prescribed guideline-recommended high-intensity statin therapy if their clinician was sent an automated reminder with information about their CVD hx, prior statin use and hx of statin associated side effects
@mki3190 @PACEcme @cpcannon @FrancescoPaneni @DrPenson @JohnKastelein @ehjopen @GaronGenevieve @SABOURETCardio @pabeda1 @DrMarthaGulati @society_eas @ESCAdvocacy @IraqiLipid @ehj_ed SI = SAMS, due to the fact that about 95% of all statin-associated side effects are muscle related.
@maciejbanach @PACEcme @cpcannon @FrancescoPaneni @DrPenson @JohnKastelein @ehjopen @GaronGenevieve @SABOURETCardio @pabeda1 @DrMarthaGulati @society_eas @ESCAdvocacy @IraqiLipid @ehj_ed Unfortunately, you replace SI with SAMS which again are just statin associated side effects. Why the special name? Are there any head-to-head study which would support your closing statement of most-effective? 1/
Open label studies have found more prevalence of statin associated side effects implying nocebo effects. Drucebo effect is nocebo effect associated with a drug. Data has shown that drucebo effects contributed to between 38% and 78% of muscle pain. https://t.co/heG6RG8jae
Nocebo effects in cardiology. #CardioTwitter #MedTwitter Sharing an old article coz one prominent account talked about statin associated Side effects. https://t.co/ReFMNud6X0
In adults with possible statin associated side effects, trial at least 2 statins, with one at the lowest approved dose AND a trial of alternative dosing regimens BEFORE reaching for non-statin therapies
RT @cardiomet_CE: 13) The #SAMSON trial suggests as much as 90% of reported #statin associated side effects are due to the #nocebo effect
RT @cardiomet_CE: 13) The #SAMSON trial suggests as much as 90% of reported #statin associated side effects are due to the #nocebo effect
RT @cardiomet_CE: 7) Before introducing the new definition, let’s revisit some basics. Patients generally recognize the benefits of #stati…
13) The #SAMSON trial suggests as much as 90% of reported #statin associated side effects are due to the #nocebo effect
7) Before introducing the new definition, let’s revisit some basics. Patients generally recognize the benefits of #statin therapy but are also very concerned with statin-associated side effects.